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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SYCP3 Gene

protein-coding   GIFtS: 60
GCID: GC12M102105

synaptonemal complex protein 3
 Explore 11 diseases affiliated with
SYCP3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SYCP3    

Aliases
for SYCP3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Synaptonemal Complex Protein 31 2
SCP32 3 5
COR12 5
SPGF42
SCP-33

External Ids:    HGNC: 181301   Entrez Gene: 505112   Ensembl: ENSG000001393517   OMIM: 6047595   UniProtKB: Q8IZU33   

Export aliases for SYCP3 gene to outside databases

Previous GC identifers: GC12U990147 GC12M100624 GC12M099182


Summaries
for SYCP3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SYCP3:
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis,
recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males
and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that
encode the same protein. (provided by RefSeq, May 2010)

UniProtKB/Swiss-Prot: SYCP3_HUMAN, Q8IZU3
Function: Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes
during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis
development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity)

Gene Wiki entry for SYCP3


Genomic Views
for SYCP3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SYCP3 gene promoter:
         AML1a   Nkx2-2   FOXD3   Nkx2-5   STAT5A   NF-YB   Ik-2   IRF-7A   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SYCP3 promoter sequence
   Search SABiosciences Chromatin IP Primers for SYCP3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYCP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q   Ensembl cytogenetic band:  12q23.2   HGNC cytogenetic band: 12q23.2

SYCP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYCP3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M102105:  view genomic region     (about GC identifiers)

Start:
 102,122,426 bp from pter      End:
 102,133,250 bp from pter
Size:
 10,825 bases      Orientation:
 minus strand

Proteins
for SYCP3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SYCP3_HUMAN, Q8IZU3 (See protein sequence)
Recommended Name: Synaptonemal complex protein 3  
Size: 236 amino acids; 27729 Da
Subunit: Interacts with SYCP2 (By similarity)
Subcellular location: Nucleus (By similarity). Chromosome (By similarity). Note=In tripartite segments of synaptonemal
complexes, irrespective of whether these are synapsed or unsynapsed (By similarity)

Explore the universe of human proteins at neXtProt for SYCP3: NX_Q8IZU3

Post-translational modifications:

  • Phosphorylated (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8IZU3

    • SYCP3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001171419.1  NP_001171420.1  NP_710161.1  

    ENSEMBL proteins: 
     ENSP00000266743   ENSP00000376658   ENSP00000376655  
    Reactome Protein details: Q8IZU3
    Human Recombinant Protein Products: 
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    Novus Biologicals SYCP3 Proteins
    Novus Biologicals SYCP3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SYCP3

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005694chromosome IEA--


    SYCP3 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for SYCP3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SYCP3 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR006888 Cor1/Xlr/Xmr

    Graphical View of Domain Structure for InterPro Entry Q8IZU3

    ProtoNet protein and cluster: Q8IZU3

    1 Blocks protein family: IPB006888 Cor1/Xlr/Xmr conserved region

    UniProtKB/Swiss-Prot: SYCP3_HUMAN, Q8IZU3
    Similarity: Belongs to the XLR/SYCP3 family


    Function
    for SYCP3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SYCP3_HUMAN, Q8IZU3
    Function: Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes
    during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis
    development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity)

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmid: SYCP3 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYCP3 (see all 7)
    OriGene shRNA RFP: SYCP3
    OriGene siRNA: SYCP3
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for SYCP3

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--


    SYCP3 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Sycp3tm1Hoog for SYCP3
         2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Sycp3):
     endocrine/exocrine gland  reproductive system 

    SYCP3 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for SYCP3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Meiotic Synapsis
    		Meiotic Synapsis1.00
    		Meiosis0.70
    		Telomere clustering at the nuclear membrane0.82
    		Chromosome Maintenance0.56
    2Synapsis
    		Synapsis1.00
    		Formation of Axial/Lateral Elements of Synaptonemal Complex0.56
    3Meiosis
    		Meiosis1.00
    4Cell Cycle
    		Cell Cycle1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for SYCP3
        Meiosis


    5/7        Reactome Pathways for SYCP3 (see all 7)
        Synapsis
    Meiotic Synapsis
    Cell Cycle
    Meiosis
    Chromosome Maintenance



    SYCP3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SYCP3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/28 Interacting proteins for SYCP3 (Q8IZU32, 3 ENSP000002667434) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BRCA2P515872, ENSP000003694974MINT-8303514 MINT-8303444 STRING: ENSP00000369497
    PABPC1P119403, ENSP000003130074I2D: score=1 STRING: ENSP00000313007
    SMC1AQ146833, ENSP000003234214I2D: score=1 STRING: ENSP00000323421
    SMC3Q9UQE73, ENSP000003547204I2D: score=1 STRING: ENSP00000354720
    SYCP2Q9BX263, ENSP000003501624I2D: score=1 STRING: ENSP00000350162
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007141male meiosis I NAS15218256
    GO:0035093spermatogenesis, exchange of chromosomal proteins IMP14643120
    GO:0051301cell division IEA--


    SYCP3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SYCP3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SYCP3
    Search CenterWatch for drugs/clinical trials and news about SYCP3 

    Transcripts
    for SYCP3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SYCP3 gene (3 alternative transcripts): 
    NM_001177948.1  NM_001177949.1  NM_153694.4  

    Unigene Cluster for SYCP3:

    Synaptonemal complex protein 3
    Hs.506504  [show with all ESTs]
    Unigene Representative Sequence: BC062662
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000478238 ENST00000266743 ENST00000478139(uc001tis.3) ENST00000392927(uc001tir.3 uc001tiq.3)
    ENST00000392924

    miRNA
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    Inhib. RNA
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    Clone
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SYCP3

    Additional cDNA sequence: 

    AF492003.1 AF517774.1 BC062662.1 

    10 DOTS entries:

    DT.95258155  DT.440957  DT.121178796  DT.40240243  DT.40264019  DT.456021  DT.91716996  DT.100818423 
    DT.121178791  DT.91823852 

    24/32 AceView cDNA sequences (see all 32):

    AF517774 BC062662 AF492003 AA971665 AW972555 AK125930 BU852431 AI214984 
    NM_153694 BU165769 BG207820 AI075991 AL045184 AI285929 BG202454 BU568927 
    BQ428625 BU568620 BG215085 BG212523 BG202574 BG189124 BG201028 BE972623 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SYCP3    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8
    SP1:                                -                                                   
    SP2:                    -           -                                                   
    SP3:                                -                                                   
    SP4:                    -           -                                                   
    SP5:                    -                                                               


    ECgene alternative splicing isoforms for SYCP3

    Expression
    for SYCP3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SYCP3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTATTCTGAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SYCP3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    OvaryOvigerous CordXX Germ CellsFemale Gametocytes, Germ Cells
    Reproductive SystemEarly GonadPrimordial Germ CellsGerm Cells
    TestisSeminiferous TubulesPrimary SpermatocyteGerm Cells, Male Gametocytes
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 7 LifeMap Cells 
    NameCategory
    Ovarian tissue-dissociated cells (human) (Primary Cell)Ovary, Reproductive System
    ES-J1 (Embryonic Stem Cell)Early Embryo, Inner Cell Mass
    Long-time differentiated EBs (Derivation of embryo...)
    Oocytes (Oocyte formation by ...)
    Human oogonial stem cells (Oocyte formation by ...)
    Human oogonial stem cells (Oocyte formation by ...)
    Oocytes (Oocyte formation by ...)

    See SYCP3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SYCP3

    SOURCE GeneReport for Unigene cluster: Hs.506504

    UniProtKB/Swiss-Prot: SYCP3_HUMAN, Q8IZU3
    Tissue specificity: Testis-specific

        SABiosciences Expression via Pathway-Focused PCR Array including SYCP3: 
              Embryonic Stem Cells in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for SYCP3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for SYCP3 gene from 4/12 species (see all 12)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Sycp31 , 5 synaptonemal complex protein 31, 5 84.05(n)1
    72.65(a)1    		   10 (43.94 cM)5
    209621  NM_011517.21  NP_035647.21 
     884595695 
    chicken
    (Gallus gallus)    		 Aves SYCP31 synaptonemal complex protein 3 78.44(n)
    77.02(a)    		   418097  XM_416330.3  XP_416330.1 
    lizard
    (Anolis carolinensis)    		 Reptilia SYCP36
    		 --
    		 71(a)
    		 1 ↔ 1
    		 5(17375036-17381668)
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.154742 Transcribed sequence with weak similarity to protein more 77.93(n)    BQ074134.1 


    ENSEMBL Gene Tree for SYCP3 (if available)
    TreeFam Gene Tree for SYCP3 (if available) 

    Paralogs
    for SYCP3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SYCP3 gene

    SYCP3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SYCP3
    PGOHUM00000244626


    Genomic Variants
    for SYCP3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/215 NCBI SNPs in SYCP3 are shown (see all 215)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 12 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs772881921,2
    		C,--99181765(+) ACATAT/GTCACA 3 -- ds50012Minor allele frequency- G:0.20WA 120
    rs177238331,2
    		C,F,--99182109(+) GAAAGC/TTTAAT 3 -- ut315Minor allele frequency- T:0.01NA 146
    rs1150134751,2
    		C,F,--99182131(+) AGGAAT/CAGTTG 3 -- ut311Minor allele frequency- C:0.02WA 118
    rs733924231,2
    		C,F,--99183748(+) TAACAT/CTTAGA 3 -- int13Minor allele frequency- C:0.07WA 122
    rs733924251,2
    		C,F,--99183813(+) TCAGAG/CCATTG 3 -- int13Minor allele frequency- C:0.07WA 122
    rs124236351,2
    		H--99183899(+) tttttA/Ttgagg 3 -- int1 trp30--------
    rs762733691,2
    		F,--99184047(+) AGCTAT/CTTTTG 3 -- int11Minor allele frequency- C:0.03EA 120
    rs1116860461,2
    		--99184133(+) GATCTC/TGCCTT 3 -- int11Minor allele frequency- T:0.50CSA 2
    rs802917871,2
    		C,F,--99184256(+) GTTATT/CTTAAC 3 -- int12Minor allele frequency- C:0.06WA NA 238
    rs775822091,2
    		F,--99184269(+) GTATTT/CGCACA 3 -- int11Minor allele frequency- C:0.02WA 118

    HapMap Linkage Disequilibrium report for SYCP3 (102122426 - 102133250 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for SYCP3
         1 CNV: 35032
    Human Gene Mutation Database (HGMD): SYCP3

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for SYCP3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SYCP3 for disorders           About GeneDecksing

    OMIM gene information: 604759   
    OMIM disorders: 270960  
    UniProtKB/Swiss-Prot: SYCP3_HUMAN, Q8IZU3
  • Defects in SYCP3 are the cause of spermatogenic failure type 4 (SPGF4) [MIM:270960]. An infertility disorder
    • characterized by azoospermia, a condition of having no sperm present in the ejaculate. Testicular histology shows
    arrest of spermatogenesis at the pachytene stage of primary spermatocytes

    11 diseases for SYCP3:    About MalaCards
    azoospermia    azoospermia due to perturbations of meiosis    beta-mannosidosis    reflex sympathetic dystrophy
    gemistocytic astrocytoma    ataxia telangiectasia    spontaneous abortion    mannosidosis
    infertility    ataxia    astrocytoma

    4 diseases from the University of Copenhagen DISEASES database for SYCP3:
    Azoospermia     beta-mannosidosis     Gemistocytic astrocytoma     Infertility

    3 Novoseek disease relationships for SYCP3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    azoospermia 80.4 11 14643120 (3), 16824523 (2), 16520322 (1), 16227348 (1) (see all 5)
    ataxia telangiectasia 47.9 2 15218256 (1)
    infertility 40.1 1 16520322 (1)

    Genetic Association Database (GAD): SYCP3
    Human Genome Epidemiology (HuGE) Navigator: SYCP3 (5 documents)

    Export disorders for SYCP3 gene to outside databases

    Publications
    for SYCP3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SYCP3 gene, integrated from 9 sources (see all 41):
    (articles sorted by number of sources associating them with SYCP3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Azoospermia in patients heterozygous for a mutation in SYCP3. (PubMed id 14643120)1, 2, 4, 9 Miyamoto T.... Lamb D.J. (2003)
    2. A new gene family (FAM9) of low-copy repeats in Xp22.3 expressed exclusively in testis: implications for recombinations in this region. (PubMed id 12213195)1, 2, 3 Martinez-Garay I....Kutsche K. (2002)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Comparative genome sequence analysis of the Bpa/Str region in mouse and man. (PubMed id 10854409)1, 3 Mallon A.-M....Brown S.D.M. (2000)
    5. Testicular expression of synaptonemal complex protein 3 (SYCP3) messenger ribonucleic acid in 110 patients with nonobstructive azoospermia. (PubMed id 16824523)1, 9 Aarabi M....Akhondi M.M. (2006)
    6. Mutations of the SYCP3 gene in women with recurrent pregnancy loss. (PubMed id 19110213)1, 9 Bolor H....Kurahashi H. (2009)
    7. Ectopic expression of X-linked lymphocyte-regulated p rotein pM1 renders tumor cells resistant to antitumor immunity. (PubMed id 20395201)1, 9 Kang T.H....Kim T.W. (2010)
    8. Mammalian neo-oogenesis and expression of meiosis-specific protein SCP3 in adult human and monkey ovaries. (PubMed id 18256545)1, 9 Bukovsky A....Dominguez R. (2008)
    9. Kinetics of meiosis in azoospermic males: a joint histological and cytological approach. (PubMed id 15218256)1, 9 de Boer P....te Velde E.R. (2004)
    10. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)

    External Searches for SYCP3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SYCP3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 50511 HGNC: 18130 AceView: SYCP3 Ensembl:ENSG00000139351 euGenes: HUgn50511
    ECgene: SYCP3 H-InvDB: SYCP3

    Other Databases showing SYCP3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SYCP3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SYCP3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SYCP3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SYCP3 gene:
    Search GeneIP for patents involving SYCP3

    GeneCards and IP:
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