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SYCE2 Gene

protein-coding   GIFtS: 47
GCID: GC19M013010

Synaptonemal Complex Central Element Protein 2

  Search for SYCE2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Synaptonemal Complex Central Element Protein 21 2
CESC12 3 5
Central Element Synaptonemal Complex 11
Central Element Synaptonemal Complex Protein 13

External Ids:    HGNC: 274111   Entrez Gene: 2561262   Ensembl: ENSG000001618607   OMIM: 6114875   UniProtKB: Q6PIF23   

Export aliases for SYCE2 gene to outside databases

Previous GC identifers: GC19M012872 GC19U900619 GC19M012581


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SYCE2 Gene:
The protein encoded by this gene is part of the synaptonemal complex formed between homologous chromosomes during
meiotic prophase. The encoded protein associates with SYCP1 and SYCE1 and is found only where chromosome cores
are synapsed. (provided by RefSeq, Dec 2012)

GeneCards Summary for SYCE2 Gene:
SYCE2 (synaptonemal complex central element protein 2) is a protein-coding gene.

UniProtKB/Swiss-Prot: SYCE2_HUMAN, Q6PIF2
Function: Major component of the transverse central element of synaptonemal complexes (SCS), formed between
homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central
element. May have a role in the synaptonemal complex assembly, stabilization and recombination (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011295.12  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SYCE2 gene promoter:
         AP-1   CUTL1   Nkx2-5   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SYCE2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SYCE2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.13

SYCE2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYCE2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M013010:  view genomic region     (about GC identifiers)

Start:
13,009,600 bp from pter      End:
13,030,090 bp from pter
Size:
20,491 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SYCE2_HUMAN, Q6PIF2 (See protein sequence)
Recommended Name: Synaptonemal complex central element protein 2  
Size: 218 amino acids; 24690 Da
Subunit: Homodimer. Found in a complex with SYCP1 and SYCE1. Interacts with SYCP1, SYCE1 and SYCE3 (By similarity)
Secondary accessions: B4DYD3

Explore the universe of human proteins at neXtProt for SYCE2: NX_Q6PIF2

Explore proteomics data for SYCE2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SYCE2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001099048.1  
    ENSEMBL proteins: 
     ENSP00000293695   ENSP00000466359  
    Reactome Protein details: Q6PIF2

    SYCE2 Human Recombinant Protein Products:

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    Novus Biologicals SYCE2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for SYCE2

     
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    SYCE2 Antibody Products:

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    Cloud-Clone Corp. ELISAs for SYCE2
    Cloud-Clone Corp. CLIAs for SYCE2
    Search eBioscience for ELISAs for SYCE2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q6PIF2

    UniProtKB/Swiss-Prot: SYCE2_HUMAN, Q6PIF2
    Similarity: Belongs to the SYCE family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYCE2_HUMAN, Q6PIF2
    Function: Major component of the transverse central element of synaptonemal complexes (SCS), formed between
    homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central
    element. May have a role in the synaptonemal complex assembly, stabilization and recombination (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with SYCE2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SYCE2:
     Synthetic lethal with c-Myc af 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Syce2):
     endocrine/exocrine gland  reproductive system 

    Find genes that share phenotypes with SYCE2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SYCE2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SYCE2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SYCE2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SYCE2

    miRNA
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    Block miRNA regulation of human, mouse, rat SYCE2 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate SYCE2:
    hsa-miR-551b*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SYCE2
    Predesigned siRNA for gene silencing in human, mouse, rat SYCE2

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    Clone
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    GenScript: all cDNA clones in your preferred vector: SYCE2 (NM_001105578)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYCE2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SYCE2

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYCE2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SYCE2_HUMAN, Q6PIF2: Nucleus. Note=Associates with chromatin. In prophase I stage of meiosis, localizes in the
    transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found
    only where the chromosome cores are synapsed. Colocalizes with SYCE1 in the central elements (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    extracellular1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000801central element ISS--

    Find genes that share ontologies with SYCE2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SYCE2 About    
    See pathways by source

    SuperPathContained pathways About
    1Packaging Of Telomere Ends
    Meiotic Synapsis0.66
    Chromosome Maintenance0.62
    2Cell Cycle, Mitotic
    Cell Cycle0.90
    3Meiosis (REACTOME)
    Meiosis0.74


    Find genes that share SuperPaths with SYCE2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for SYCE2
        Meiotic synapsis


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SYCE2
    Interactions:

        Search GeneGlobe Interaction Network for SYCE2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    Selected Interacting proteins for SYCE2 (ENSP000002936954) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HSPA2ENSP000002472074STRING: ENSP00000247207
    LMNB1ENSP000002613664STRING: ENSP00000261366
    RAD21ENSP000002973384STRING: ENSP00000297338
    SMC1BENSP000003500364STRING: ENSP00000350036
    SMC3ENSP000003547204STRING: ENSP00000354720
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007130synaptonemal complex assembly IC15944401
    GO:0051301cell division ----

    Find genes that share ontologies with SYCE2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SYCE2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SYCE2 gene: 
    NM_001105578.1  

    Unigene Cluster for SYCE2:

    Synaptonemal complex central element protein 2
    Hs.655173  [show with all ESTs]
    Unigene Representative Sequence: AK097443
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000293695(uc002mvr.2) ENST00000592819 ENST00000591229
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SYCE2 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate SYCE2:
    hsa-miR-551b*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SYCE2
    Predesigned siRNA for gene silencing in human, mouse, rat SYCE2
    Clone
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    OriGene clones in human, mouse for SYCE2 (see all 7)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SYCE2 (NM_001105578)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SYCE2
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat SYCE2
      QuantiFast Probe-based Assays in human, mouse, rat SYCE2

    Additional mRNA sequence: 

    AK097443.1 AK302373.1 BC035819.2 

    3 DOTS entries:

    DT.100008994  DT.40240601  DT.100725587 

    18 AceView cDNA sequences:

    BM804415 CR620067 BC035819 AK097443 T19174 BX098301 AI001057 AI750568 
    AW628765 BX337823 AW102741 AA813484 AA565544 AA931303 T99722 T99723 
    BG676366 BX414042 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SYCE2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTTCTATAAT
    SYCE2 Expression
    About this image


    SYCE2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
     
     Testis (Reproductive System)
    SYCE2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SYCE2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655173
        Custom PCR Arrays for SYCE2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SYCE2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SYCE2 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Syce21 , 5 synaptonemal complex central element protein 21, 5 78.34(n)1
    73.89(a)1
      8 (41.25 cM)5
    718461  NM_001168246.11  NP_001161718.11 
     848721115 
    chicken
    (Gallus gallus)
    Aves SYCE21 synaptonemal complex central element protein 2 64.24(n)
    53.64(a)
      100859541  XM_003643385.2  XP_003643433.1 
    lizard
    (Anolis carolinensis)
    Reptilia SYCE26
    synaptonemal complex central element protein 2
    48(a)
    1 ↔ 1
    2(27703741-27705606)


    ENSEMBL Gene Tree for SYCE2 (if available)
    TreeFam Gene Tree for SYCE2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SYCE2 gene

    Find genes that share paralogs with SYCE2           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for SYCE2
    PGOHUM00000239571


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SYCE2 (see all 456)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs342868191,2
    C--12590956(+) TGGGC-/TTTTTT 1 -- int11Minor allele frequency- T:0.00NA 2
    rs1395468481,2
    --12946370(+) AGAAGG/TGATGA 1 -- ds50010--------
    rs1450738111,2
    C--12946400(+) GGGCTC/TGGCGC 1 -- ds50010--------
    rs1927261141,2
    --12946403(+) CTCGGC/TGCAGT 1 -- ds50010--------
    rs735053291,2
    C--12946597(+) TAAAAC/AGGAGG 1 -- ds50011Minor allele frequency- A:0.50WA 2
    rs1475561131,2
    C--12946704(+) TGGGCA/GGAGGT 1 -- ds50010--------
    rs1156813371,2
    C,F--12946709(+) AGAGGT/ACAGCT 1 -- ds50011Minor allele frequency- A:0.11WA 118
    rs1491205501,2
    --12946736(+) CTTCCA/GATGTG 1 -- ds50010--------
    rs1431663291,2
    C--12946878(+) TGGGGC/GTGGGG 1 -- ut310--------
    rs1179848911,2
    C,F--12946922(+) GGCCTA/GTGGCA 1 -- ut311Minor allele frequency- G:0.01NA 120

    HapMap Linkage Disequilibrium report for SYCE2 (13009600 - 13030090 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SYCE2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2668234CNV Deletion23128226
    nsv911082CNV Loss21882294
    nsv833754CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SYCE2
    DNA2.0 Custom Variant and Variant Library Synthesis for SYCE2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611487    OMIM disorders: --


    Find genes that share disorders with SYCE2           About GenesLikeMe

    Genetic Association Database (GAD): SYCE2
    Human Genome Epidemiology (HuGE) Navigator: SYCE2 (3 documents)

    Export disorders for SYCE2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SYCE2 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with SYCE2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    2. Two novel proteins recruited by synaptonemal complex protein 1 (SYCP1) are at the centre of meiosis. (PubMed id 15944401)1, 3 Costa Y....Cooke H.J. (J. Cell. Sci. 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (Nature 2004)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. Seventy-five genetic loci influencing the human red blood cell. (PubMed id 23222517)1 van der Harst P....Chambers J.C. (Nature 2012)
    8. Structural analysis of the human SYCE2-TEX12 complex provides molecular insights into synaptonemal complex assembly. (PubMed id 22870393)1 Davies O.R....Pellegrini L. (Open Biol 2012)
    9. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    10. SYCE2 is required for synaptonemal complex assembly, double strand break repair, and homologous recombination. (PubMed id 17339376)1 Bolcun-Filas E....Cooke H.J. (J. Cell Biol. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 256126 HGNC: 27411 AceView: LOC256126 Ensembl:ENSG00000161860 euGenes: HUgn256126
    ECgene: SYCE2 H-InvDB: SYCE2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SYCE2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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