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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SYBU Gene

protein-coding   GIFtS: 50
GCID: GC08M110586

syntabulin (syntaxin-interacting)
 Explore 6 diseases affiliated with
SYBU via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SYBU    

Aliases
for SYBU gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Syntabulin (Syntaxin-Interacting)1 2     Golgi-Localized Protein2
GOLSYN1 2 3 5     GOLSYN A Protein2
KIAA14721 3 5     GOLSYN B Protein2
OCSYN1 2     GOLSYN C Protein2
SNPHL1 2     Implicated In Syntaxin Trafficking In Neurons2
Golgi-Localized Syntaphilin-Related Protein2 3     Microtubule-Associated Protein2
Syntaxin-1-Binding Protein2 3     Syntabulin1
FLJ203661     

External Ids:    HGNC: 260111   Entrez Gene: 556382   Ensembl: ENSG000001476427   OMIM: 6115685   UniProtKB: Q9NX953   

Export aliases for SYBU gene to outside databases

Previous GC identifer: GC08M105908


Summaries
for SYBU gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SYBU:
Syntabulin/GOLSYN is part of a kinesin motor-adaptor complex that is critical for the anterograde axonal transport of
active zone components and contributes to activity-dependent presynaptic assembly during neuronal development (Cai et
al., 2007 (PubMed 17611281)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: SYBU_HUMAN, Q9NX95
Function: Part of a kinesin motor-adapter complex that is critical for the anterograde axonal transport of active zone
components and contributes to activity-dependent presynaptic assembly during neuronal development (By similarity)

Gene Wiki entry for SYBU (GOLSYN)


Genomic Views
for SYBU gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.1  NT_008046.16  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for SYBU
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SYBU promoter sequence
   Search SABiosciences Chromatin IP Primers for SYBU

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SYBU


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q23.2   Ensembl cytogenetic band:  8q23.2   HGNC cytogenetic band: 8q23.2

SYBU Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SYBU gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M110586:  view genomic region     (about GC identifiers)

Start:
 110,586,207 bp from pter      End:
 110,704,020 bp from pter
Size:
 117,814 bases      Orientation:
 minus strand

Proteins
for SYBU gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SYBU_HUMAN, Q9NX95 (See protein sequence)
Recommended Name: Syntabulin  
Size: 663 amino acids; 72388 Da
Subunit: Interacts with STX1A and KIF5B
Subcellular location: Isoform 1: Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Note=Colocalizes with syntaxin vesicles
along microtubules in neuronal processes
Subcellular location: Isoform 3: Golgi apparatus membrane; Single-pass membrane protein
Subcellular location: Isoform 4: Golgi apparatus membrane; Single-pass membrane protein
Subcellular location: Isoform 5: Golgi apparatus membrane; Single-pass membrane protein
Secondary accessions: A8K354 B3KQX3 B3KU61 Q5R1T1 Q5R1T2 Q5R1T3 Q5Y2M6 Q8ND49 Q8TCR6 Q96D80 Q9P256
Alternative splicing: 5 isoforms:  Q9NX95-1   Q9NX95-2   Q9NX95-3   Q9NX95-4   Q9NX95-5   

Explore the universe of human proteins at neXtProt for SYBU: NX_Q9NX95

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NX95

    • SYBU Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (15 alternative transcripts): 
    NP_001093213.1  NP_001093214.1  NP_001093215.1  NP_001093216.1  NP_001093217.1  NP_001093218.1  NP_001093219.1  NP_001093220.1  
    NP_001093221.1  NP_001093222.1  NP_001093223.1  NP_001093224.1  NP_001093225.1  NP_001093226.1  NP_060256.3  

    ENSEMBL proteins: 
     ENSP00000433446   ENSP00000415654   ENSP00000436266   ENSP00000382019   ENSP00000414748  
     ENSP00000436041   ENSP00000434871   ENSP00000276646   ENSP00000432501   ENSP00000432962  
     ENSP00000433941   ENSP00000434679   ENSP00000431492   ENSP00000436850   ENSP00000436797  
     ENSP00000432835   ENSP00000434074   ENSP00000436908   ENSP00000431469   ENSP00000435433  
     ENSP00000434158   ENSP00000434840   ENSP00000435224   ENSP00000432291   ENSP00000436520  
     ENSP00000434061   ENSP00000431895   ENSP00000434612   ENSP00000407118   ENSP00000402652  
     ENSP00000403544   ENSP00000386154   ENSP00000404369   ENSP00000386196  

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    Uscn Proteins for SYBU

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005856cytoskeleton IEA--
    GO:0016021integral to membrane IEA--
    GO:0016023cytoplasmic membrane-bounded vesicle IEA--


    SYBU for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for SYBU gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SYBU for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR026198 Syntabulin

    Graphical View of Domain Structure for InterPro Entry Q9NX95

    ProtoNet protein and cluster: Q9NX95


    Function
    for SYBU gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SYBU_HUMAN, Q9NX95
    Function: Part of a kinesin motor-adapter complex that is critical for the anterograde axonal transport of active zone
    components and contributes to activity-dependent presynaptic assembly during neuronal development (By similarity)

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYBU
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate SYBU (see all 18):
    hsa-miR-3673 hsa-miR-3194-5p hsa-miR-301a hsa-miR-499-5p hsa-miR-1276 hsa-miR-3658 hsa-miR-130b hsa-miR-31*
    SwitchGear 3'UTR luciferase reporter plasmid: SYBU 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYBU
    OriGene shRNA RFP: SYBU
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16713569
    GO:0017075syntaxin-1 binding IEA--
    GO:0019894kinesin binding IEA--


    SYBU for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SYBU:
     Increased G1 DNA content 


    Pathways & Interactions
    for SYBU gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SYBU

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/7 Interacting proteins for SYBU (Q9NX951, 2, 3 ENSP000002766464) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN1P542531, 2, 3, ENSP000002447694EBI-1019860,EBI-930964 MINT-2874423 MINT-2874442 MINT-2874461 I2D: score=3 STRING: ENSP00000244769
    RPL29P479142, 3, ENSP000002941894MINT-63765 I2D: score=5 STRING: ENSP00000294189
    DTNBP1Q96EV83, ENSP000003416804I2D: score=2 STRING: ENSP00000341680
    KIF5BP331763, ENSP000003070784I2D: score=1 STRING: ENSP00000307078
    EXOC1Q9NV703, ENSP000003265144I2D: score=1 STRING: ENSP00000326514
    About this table

    Drugs & Compounds
    for SYBU gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SYBU
    Search CenterWatch for drugs/clinical trials and news about SYBU 

    Transcripts
    for SYBU gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SYBU gene (15 alternative transcripts): 
    NM_001099743.1  NM_001099744.1  NM_001099745.1  NM_001099746.1  NM_001099747.1  NM_001099748.1  NM_001099749.1  NM_001099750.1  
    NM_001099751.1  NM_001099752.1  NM_001099753.1  NM_001099754.1  NM_001099755.1  NM_001099756.1  NM_017786.5  

    Unigene Cluster for SYBU:

    Syntabulin (syntaxin-interacting)
    Hs.390738  [show with all ESTs]
    Unigene Representative Sequence: AB195679
    18/39 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 39):
    ENST00000533895 ENST00000424158(uc010mct.3) ENST00000532779(uc011lhw.2)
    ENST00000399066(uc003yni.4) ENST00000446070 ENST00000528331 ENST00000529175(uc003ynh.4)
    ENST00000276646(uc003ynk.4 uc003ynj.4 uc010mco.3) ENST00000528647
    ENST00000533065 ENST00000529690 ENST00000533171 ENST00000527707 ENST00000533394
    ENST00000532594 ENST00000528045 ENST00000527664 ENST00000528735

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SYBU
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate SYBU (see all 18):
    hsa-miR-3673 hsa-miR-3194-5p hsa-miR-301a hsa-miR-499-5p hsa-miR-1276 hsa-miR-3658 hsa-miR-130b hsa-miR-31*
    SwitchGear 3'UTR luciferase reporter plasmid: SYBU 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SYBU
    OriGene shRNA RFP: SYBU
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SYBU
    Clone
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    Additional cDNA sequence: 

    AB040905.1 AB195676.1 AB195677.1 AB195678.1 AB195679.1 AK000373.1 AK055246.1 AK090559.1 
    AK093952.1 AK096558.1 AK290469.1 AK297182.1 AL713645.1 AL834406.1 AY705385.1 BC012082.1 

    20 DOTS entries:

    DT.444579  DT.120642776  DT.95269030  DT.100754966  DT.95269032  DT.120642737  DT.101956548  DT.95269031 
    DT.120642768  DT.100754964  DT.91720083  DT.120642684  DT.100754968  DT.97822923  DT.99927828  DT.120642765 
    DT.120642682  DT.120642696  DT.120642744  DT.120642754 

    24/124 AceView cDNA sequences (see all 124):

    CD702811 AL713645 AK091374 AA878208 BM695876 AI004340 AA864514 AW005782 
    T08208 AA255630 AI861965 BM921662 Z38812 BX094310 BQ016438 AK096558 
    BC012082 AL834406 AA937104 BM666954 AK090559 AI889021 AW517294 BU607867 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for SYBU (see all 9)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c · 5d · 5e ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d · 7e
    SP1:                    -     -           -     -     -                                                                           
    SP2:                          -           -     -     -                                                                           
    SP3:        -     -     -     -           -     -     -                                                                           
    SP4:                    -     -           -     -     -                 -     -     -                                             
    SP5:                    -     -                 -     -                                                                           


    ECgene alternative splicing isoforms for SYBU

    Expression
    for SYBU gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SYBU expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATGAAAATAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SYBU expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainCerebral CortexBrain
    BrainStriatumBrain
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    PureStem™ mesenchymal progenitor MEL2 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ progenitor Z1 (Embryonic Progenitor Cell)

    See SYBU Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SYBU

    SOURCE GeneReport for Unigene cluster: Hs.390738

    UniProtKB/Swiss-Prot: SYBU_HUMAN, Q9NX95
    Tissue specificity: Isoform 3, isoform 4 and isoform 5 are expressed in HeLa cell line (at protein level). Isoform 3 is
    expressed in fetal and adult brain. Isoform 4 is expressed in numerous fetal tissues (brain, kidney, liver, lung, and
    thymus) and in adult brain, kidney, liver, lung, pancreas, colon, prostate, small intestine, testis and thymus.
    Isoform 5 is expressed in fetal brain, brain and small intestine

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    In Situ
    Assay Products:     
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    Orthologs
    for SYBU gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for SYBU gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Sybu1 , 5 syntabulin (syntaxin-interacting)1, 5 83.96(n)1
    85.78(a)1    		   15 (16.91 cM)5
    3196131  NM_176998.41  NP_795972.21 
     446718595 
    chicken
    (Gallus gallus)    		 Aves SYBU1 syntabulin (syntaxin-interacting) 68.21(n)
    67.13(a)    		   420277  XM_418389.3  XP_418389.3 
    lizard
    (Anolis carolinensis)    		 Reptilia SYBU6
    		 --
    		 62(a)
    		 1 ↔ 1
    		 4(10672726-10738992)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.84412 Xenopus laevis transcribed sequence with weak similarity more 77.58(n)    CD361419.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii sybu1 syntabulin (syntaxin-interacting) 53.76(n)
    47.71(a)    		   568207  NM_001077173.1  NP_001070641.1 


    ENSEMBL Gene Tree for SYBU (if available)
    TreeFam Gene Tree for SYBU (if available) 

    Paralogs
    for SYBU gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SYBU gene
    SNPH2  
    1 SIMAP similar gene for SYBU using alignment to 17 protein entries:     SYBU_HUMAN (see all proteins):
    SNPH

    SYBU for paralogs           About GeneDecksing



    Genomic Variants
    for SYBU gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2038 NCBI SNPs in SYBU are shown (see all 2038)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 8 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1118614371,2
    		C,--105976362(+) ACATGG/AATGAA 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1138554221,2
    		C,--105976422(+) ATACCG/ACATGT 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs792599951,2
    		C,F,--105976647(+) AATAAA/TACAAA 1 -- us2k11Minor allele frequency- T:0.06WA 118
    rs733192001,2
    		C,--105976693(+) CATTCG/AAAATT 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs733192021,2
    		C,--105976763(+) AAACTG/TCTGTG 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs768398881,2
    		C,--105977370(+) ACACAT/CATACA 1 -- us2k12Minor allele frequency- C:0.15CSA WA 120
    rs746470411,2
    		F,--105977851(+) CCCTGC/GCATTT 1 -- us2k11Minor allele frequency- G:0.09WA 118
    rs119955091,2
    		H--105977985(+) AATGTC/TCCTAT 1 -- us2k10--------
    rs771094241,2
    		F,--105978305(+) AATTGA/GAGGGT 1 -- us2k11Minor allele frequency- G:0.05EA 120
    rs78177731,2
    		C,--105978363(+) ACCCGG/TGGGCC 1 -- nc-transcript-variant3Minor allele frequency- T:0.10CSA WA EA 239

    HapMap Linkage Disequilibrium report for SYBU (110586207 - 110704020 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SYBU: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SYBU
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    Disorders / Diseases
    for SYBU gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SYBU for disorders           About GeneDecksing

    OMIM gene information: 611568    OMIM disorders: --

    6 diseases for SYBU:    About MalaCards
    neuronitis    glaucoma    choroiditis    ataxia
    schizophrenia    prostatitis

    Human Genome Epidemiology (HuGE) Navigator: SYBU (1 document)

    Export disorders for SYBU gene to outside databases

    Publications
    for SYBU gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SYBU gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with SYBU)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of gene for Golgi-localized syntaphilin-related protein on human chromosome 8q23. (PubMed id 15656992)1, 2, 3 Funakoshi E.... Ito F. (2005)
    2. Syntabulin is a microtubule-associated protein implicated in syntaxin transport in neurons. (PubMed id 15459722)1, 2, 3 Su Q.... Sheng Z.-H. (2004)
    3. Syntabulin-kinesin-1 family member 5B-mediated axonal transport contributes to activity-dependent presynaptic assembly. (PubMed id 17611281)1, 3 Cai Q....Sheng Z.H. (2007)
    4. Expression of m-Golsyn/Syntabulin gene during mouse brain development. (PubMed id 16750881)1, 3 Funakoshi E....Ito F. (2006)
    5. Syntabulin-mediated anterograde transport of mitochondria along neuronal processes. (PubMed id 16157705)1, 3 Cai Q....Sheng Z.H. (2005)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2 Nagase T.... Ohara O. (2000)
    8. The microtubule associated protein syntabulin is requi red for glucose-stimulated and cAMP-potentiated insulin secretion. (PubMed id 22975310)1 Ying Y....Ma X. (2012)
    9. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    10. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PubMed id 17043677)1 Camargo L.M....Brandon N.J. (2007)

    External Searches for SYBU gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing SYBU gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55638 HGNC: 26011 AceView: FLJ20366 Ensembl:ENSG00000147642 euGenes: HUgn55638
    ECgene: SYBU H-InvDB: SYBU

    Other Databases showing SYBU gene

    (According to HUGE)
    About This Section
    HUGE: KIAA1472

    Specialized Databases showing SYBU gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SYBU Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SYBU gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SYBU gene:
    Search GeneIP for patents involving SYBU

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
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