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Aliases for SWT1 Gene

Aliases for SWT1 Gene

  • SWT1 RNA Endoribonuclease Homolog (S. Cerevisiae) 2 3
  • C1orf26 3 4
  • Chromosome 1 Open Reading Frame 26 2
  • Transcriptional Protein SWT1 3
  • HsSwt1 3

External Ids for SWT1 Gene

Previous HGNC Symbols for SWT1 Gene

  • C1orf26

Summaries for SWT1 Gene

GeneCards Summary for SWT1 Gene

SWT1 (SWT1 RNA Endoribonuclease Homolog (S. Cerevisiae)) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SWT1 Gene

Genomics for SWT1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SWT1 Gene

Start:
185,150,872 bp from pter
End:
185,291,781 bp from pter
Size:
140,910 bases
Orientation:
Plus strand

Genomic View for SWT1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SWT1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SWT1 Gene

No data available for Regulatory Elements for SWT1 Gene

Proteins for SWT1 Gene

  • Protein details for SWT1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T5J6-SWT1_HUMAN
    Recommended name:
    Transcriptional protein SWT1
    Protein Accession:
    Q5T5J6
    Secondary Accessions:
    • Q8NEK9
    • Q9BZQ7
    • Q9NXQ0

    Protein attributes for SWT1 Gene

    Size:
    900 amino acids
    Molecular mass:
    103222 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA90960.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for SWT1 Gene

Proteomics data for SWT1 Gene at MOPED

Post-translational modifications for SWT1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SWT1 Gene

No data available for DME Specific Peptides for SWT1 Gene

Domains for SWT1 Gene

Protein Domains for SWT1 Gene

Suggested Antigen Peptide Sequences for SWT1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5T5J6

UniProtKB/Swiss-Prot:

SWT1_HUMAN :
  • Q5T5J6
Domain:
  • Contains 1 PINc domain.
Family:
  • Belongs to the SWT1 family.
genes like me logo Genes that share domains with SWT1: view

No data available for Gene Families for SWT1 Gene

Function for SWT1 Gene

Animal Model Products

CRISPR Products

miRNA for SWT1 Gene

miRTarBase miRNAs that target SWT1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SWT1 Gene

Localization for SWT1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SWT1 Gene

Pathways for SWT1 Gene

SuperPathways for SWT1 Gene

No Data Available

Interacting Proteins for SWT1 Gene

Gene Ontology (GO) - Biological Process for SWT1 Gene

None

No data available for Pathways by source for SWT1 Gene

Transcripts for SWT1 Gene

Unigene Clusters for SWT1 Gene

SWT1 RNA endoribonuclease homolog (S. cerevisiae):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SWT1

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for SWT1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SWT1 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b
SP1: -
SP2:
SP3: - -

Relevant External Links for SWT1 Gene

GeneLoc Exon Structure for
SWT1
ECgene alternative splicing isoforms for
SWT1

Expression for SWT1 Gene

mRNA expression in normal human tissues for SWT1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SWT1 Gene

This gene is overexpressed in Testis (5.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SWT1 Gene

SOURCE GeneReport for Unigene cluster for SWT1 Gene Hs.134183

mRNA Expression by UniProt/SwissProt for SWT1 Gene

Q5T5J6-SWT1_HUMAN
Tissue specificity: Expressed weakly in testis.
genes like me logo Genes that share expressions with SWT1: view

In Situ Assay Products

Orthologs for SWT1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SWT1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SWT1 35
  • 99.56 (n)
  • 99.11 (a)
SWT1 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C16H1ORF26 36
  • 78 (a)
OneToOne
SWT1 35
  • 87.51 (n)
  • 80.09 (a)
dog
(Canis familiaris)
Mammalia SWT1 35
  • 87.65 (n)
  • 81.14 (a)
SWT1 36
  • 79 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Swt1 35
  • 81.87 (n)
  • 71.9 (a)
Swt1 16
Swt1 36
  • 70 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SWT1 36
  • 59 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SWT1 36
  • 56 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Swt1 35
  • 83.35 (n)
  • 74.97 (a)
chicken
(Gallus gallus)
Aves SWT1 35
  • 59.97 (n)
  • 47.57 (a)
SWT1 36
  • 40 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SWT1 36
  • 37 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii swt1 36
  • 26 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG7206 36
  • 23 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SWT1 38
Species with no ortholog for SWT1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SWT1 Gene

ENSEMBL:
Gene Tree for SWT1 (if available)
TreeFam:
Gene Tree for SWT1 (if available)

Paralogs for SWT1 Gene

No data available for Paralogs for SWT1 Gene

Variants for SWT1 Gene

Sequence variations from dbSNP and Humsavar for SWT1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs883753 -- 185,261,718(+) TTGGG(G/T)TAGTA intron-variant
rs950327 -- 185,166,613(+) AGTTC(A/G)TCTTC reference, synonymous-codon
rs951428 -- 185,239,449(-) ATACC(A/G)ACAAC intron-variant
rs953701 -- 185,246,357(-) gaggt(C/T)gcagt intron-variant
rs953702 -- 185,246,347(-) tgagc(C/T)atgat intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SWT1 Gene

Variant ID Type Subtype PubMed ID
nsv521613 CNV Loss 19592680
nsv3855 CNV Insertion 18451855

Relevant External Links for SWT1 Gene

HapMap Linkage Disequilibrium report
SWT1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SWT1 Gene

Disorders for SWT1 Gene

No disorders were found for SWT1 Gene.

No data available for UniProtKB/Swiss-Prot for SWT1 Gene

Publications for SWT1 Gene

  1. Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus. (PMID: 11318611) Sood R. … Carpten J.D. (Genomics 2001) 2 3 4
  2. Comprehensive analysis of the HEPN superfamily: identification of novel roles in intra-genomic conflicts, defense, pathogenesis and RNA processing. (PMID: 23768067) Anantharaman V. … Aravind L. (Biol. Direct 2013) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4

Products for SWT1 Gene

Sources for SWT1 Gene

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