External Ids for SVIP Gene
Previous GeneCards Identifiers for SVIP Gene
Endoplasmic reticulum-associated degradation (ERAD) is the pathway by which misfolded proteins in the endoplasmic reticulum are targeted to the proteasome for degradation. Multiple specialized proteins interact with one another during ERAD to complete this process. The protein encoded by this gene is an inhibitor of ERAD, functioning to disrupt the interaction of these protein components. This downregulation of ERAD may be needed to protect the cell from overactive protein degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
GeneCards Summary for SVIP Gene
SVIP (Small VCP Interacting Protein) is a Protein Coding gene. Among its related pathways are Innate Immune System and Protein processing in endoplasmic reticulum. Gene Ontology (GO) annotations related to this gene include protein self-association.