SUV420H1 Gene
protein-coding GIFtS: 53
GCID: GC11M067922
|
|
suppressor of variegation 4-20 homolog 1 (Drosophila)
| |
Aliases
for SUV420H1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Suppressor Of Variegation 4-20 Homolog 1 (Drosophila)1 2 | | C630029K18Rik2 | | KMT5B1 2 3 | | Histone-Lysine N-Methyltransferase SUV420H12 | | Lysine N-Methyltransferase 5B2 3 | | Suv4-20h13 | | Su(Var)4-20 Homolog 12 3 | | EC 2.1.1.433 | | CGI852 5 | | Suv4-20h13 | | CGI-851 | | Suppressor Of Variegation 4-20 Homolog 13 |
Export aliases for SUV420H1 gene to outside databasesPrevious GC identifers: GC11M067680 GC11M064258 |
Summaries
for SUV420H1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SUV420H1:
This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domainsthat mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases(dsPTPases). The function of this gene has not been determined. Two alternatively spliced transcript variants havebeen found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: SV421_HUMAN, Q4FZB7Function: Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylationrepresents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatinregions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions.SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity)
Gene Wiki entry for SUV420H1
|
Genomic Views
for SUV420H1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SUV420H1 gene promoter:
NRSF form 1 Chx10 NRSF form 2
Other transcription factors
Search SABiosciences Chromatin IP Primers for SUV420H1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUV420H1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13.2 Ensembl cytogenetic band: 11q13.2 HGNC cytogenetic band: 11q13.2SUV420H1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M067922: view genomic region
(about GC identifiers)
Start:
|
67,922,330 bp from pter |
End:
|
67,981,295 bp from pter |
Size:
|
58,966 bases |
Orientation:
|
minus strand |
|
Proteins
for SUV420H1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SV421_HUMAN, Q4FZB7 (See
protein sequence)Recommended Name: Histone-lysine N-methyltransferase SUV420H1 Size: 885 amino acids; 99187 Da
Subunit: Interacts with HP1 proteins CBX1, CBX3 and CBX5. Interacts with RB1 family proteins RB1, RBL1 and RBL2 (Bysimilarity)
Subcellular location: Nucleus. Chromosome (By similarity). Note=Associated with pericentric heterochromatin. CBX1 andCBX5 are required for the localization to pericentric heterochromatin (By similarity)
Sequence caution: Sequence=AAD34080.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=AAG36937.1; Type=Frameshift; Positions=233, 249, 254, 272; Sequence=AAH98121.1; Type=Erroneous translation;Note=Wrong choice of frame; Sequence=AAI04484.1; Type=Frameshift; Positions=396; Sequence=BAA90905.1; Type=Erroneousinitiation; Note=Translation N-terminally extended;
1 PDB 3D structure from  and Proteopedia  for SUV420H1:3S8P (3D)
Secondary accessions: B7WNX7 Q3SX56 Q4V775 Q6P150 Q96E44 Q9BUL0 Q9H022 Q9H2K3 Q9NXV3 Q9Y393Alternative splicing: 3 isoforms: Q4FZB7-1 Q4FZB7-2 Q4FZB7-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SUV420H1: NX_Q4FZB7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q4FZB7
SUV420H1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_057112.3 NP_060105.3
ENSEMBL proteins: ENSP00000305899 ENSP00000411146 ENSP00000387685 ENSP00000385965 ENSP00000385640 ENSP00000385005 ENSP00000384724 ENSP00000313027 ENSP00000433589 ENSP00000406377 ENSP00000403233 ENSP00000402921
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000780 | condensed nuclear chromosome, centromeric region |
IEA | -- |
SUV420H1 for ontologies About GeneDecksing
SUV420H1 Antibody Products:
Assay Products for SUV420H1: |
Protein
Domains /
Families
for SUV420H1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SUV420H1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q4FZB7ProtoNet protein and cluster: Q4FZB7 UniProtKB/Swiss-Prot: SV421_HUMAN, Q4FZB7Similarity: Belongs to the histone-lysine methyltransferase family. Suvar4-20 subfamilySimilarity: Contains 1 SET domain |
Function
for SUV420H1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SV421_HUMAN, Q4FZB7Function: Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylationrepresents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatinregions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions.SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity)Catalytic activity: S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine +N(6)-methyl-L-lysine-[histone]Induction: Strongly down-regulated in breast cancer cellsEnzyme Number (IUBMB): EC 2.1.1.431
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUV420H1 (see all 11)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUV420H1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SUV420H1 (NM_017635) | |  | Sino Biological Human cDNA Clone for SUV420H1 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SUV420H1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUV420H1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUV420H1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0018024 | histone-lysine N-methyltransferase activity |
IDA | 17707234 | | GO:0042799 | histone methyltransferase activity (H4-K20 specific) |
IEA | -- |
SUV420H1 for ontologies About GeneDecksing
6 GenomeRNAi human phenotypes for SUV420H1:
Animal Models:
Mouse knock-out Suv420h1tm1.1Jnw for SUV420H1
10 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Suv420h1):
SUV420H1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SUV420H1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Glucocorticoid receptor regulatory network | | | 2 | Lysine degradation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for SUV420H1
1 
Kegg Pathway (Kegg details for SUV420H1):
SUV420H1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SUV420H1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/24 Interacting proteins for SUV420H1 (Q4FZB73 ENSP000003058994) via UniProtKB, MINT, STRING, and/or I2D (see all 24)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | | GO:0016571 | histone methylation |
-- | -- | | GO:0034770 | histone H4-K20 methylation |
-- | -- | | GO:0034773 | histone H4-K20 trimethylation |
IEA | -- |
SUV420H1 for ontologies About GeneDecksing
|
Drugs & Compounds
for SUV420H1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SUV420H1
2 HMDB Compounds for SUV420H1 About this table
Search CenterWatch for drugs/clinical trials and news about SUV420H1 / SV421
|
Transcripts
for SUV420H1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SUV420H1 gene (2 alternative transcripts): NM_016028.4 NM_017635.3 Unigene Cluster for SUV420H1: Suppressor of variegation 4-20 homolog 1 (Drosophila) Hs.632120 [show with all ESTs]Unigene Representative Sequence: NM_01763514 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000304363(uc009yse.1 uc001onm.1 uc001onn.1 uc009ysf.2)
ENST00000441488 ENST00000427752 ENST00000401547(uc001ono.1) ENST00000405515(uc010rqa.1)
ENST00000402789 ENST00000402185 ENST00000323599 ENST00000533271 ENST00000524672
ENST00000453170 ENST00000458496 ENST00000434573 ENST00000466295
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUV420H1 (see all 11)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUV420H1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): SUV420H1 (NM_017635) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SUV420H1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUV420H1 |
Additional cDNA sequence: AF151843.1 AF264782.1 AK000046.1 AK025183.1 AK025461.1 AK026428.1 AK225203.1 AK299201.1 AK314336.1 AL512763.1 BC002522.2 BC012933.1 BC065287.1 BC087834.1 BC098121.1 BC099714.1 BC103498.1 BC104483.1 BC108304.1 17 DOTS entries: DT.316911 DT.441923 DT.95343552 DT.455671 DT.100792656 DT.95280252 DT.95280254 DT.120711047 DT.100792650 DT.100792651 DT.120711049 DT.95149014 DT.100723574 DT.120711032 DT.86999879 DT.91866722 DT.100884527 24/362 AceView cDNA sequences (see all 362): BQ722638 BG152414 BM725783 CD519572 BC065287 AI569322 Z45174 Z42360 T34199 BM680069 AI624933 BQ269751 BF222131 BM723915 BM714970 BM452371 AA252005 NM_017635 AA702946 AA233933 CB853681 AA810205 AL512763 BE888222
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for SUV420H1 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | · | 13c | ^ | 14 | ^ | 15 | ^ | 16 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | | | | | | | | | | | | | | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | - | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SUV420H1
|
Expression
for SUV420H1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SUV420H1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATTCCTGAA
About this image
See SUV420H1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SUV420H1
SOURCE GeneReport for Unigene cluster: Hs.632120
SABiosciences Expression via Pathway-Focused PCR Array including SUV420H1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SUV420H1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SUV420H1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUV420H1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUV420H1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUV420H1 |
Orthologs
for SUV420H1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SUV420H1 gene from 6/24 species (see all 24) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SUV420H11 |
suppressor of variegation 4-20 homolog 1 (Drosophila) |
82.15(n)
85.12(a) |
|
425119 XM_422910.3 XP_422910.3 |
lizard
(Anolis carolinensis) |
Reptilia |
SUV420H16 |
-- |
81(a) |
1 ↔ 1 |
1(75144119-75159898) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.17542 |
Xenopus laevis transcribed sequence with moderate similarity more |
79.17(n) |
|
BX848518.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
suv420h11 |
suppressor of variegation 4-20 homolog 1 (Drosophila) |
60.5(n)
60.88(a) |
|
572849 NM_001007337.1 NP_001007338.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Hmt4-206 |
Histone methyltransferase 4-20 |
19(a) |
1 → many |
X(542516-550075) |
worm
(Caenorhabditis elegans) |
Secernentea |
set-41 |
Protein SET-4 |
51.04(n)
47.27(a) |
|
174045 NM_062871.3 NP_495272.1 |
ENSEMBL Gene Tree for SUV420H1 (if available)
TreeFam Gene Tree for SUV420H1 (if available) |
Paralogs
for SUV420H1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SUV420H1 gene
- SUV420H22
18/26 SIMAP similar genes for SUV420H1 using alignment to 9 protein entries: SV421_HUMAN (see all proteins)
(see all similar genes):EEF1E1 RHOA ABI2 MST132 LSM12 SH2B3
ZNF180 C12orf76 GALK2 NLN RQCD1 TUBA1C
COQ5 FLJ00047 NCKAP1L ARIH1 CDK10 HINFP
SUV420H1 for paralogs About GeneDecksing
|
Genomic Variants
for SUV420H1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SUV420H1 (67922330 - 67981295 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SUV420H1: --
Human Gene Mutation Database (HGMD): SUV420H1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SUV420H1 |
|
Disorders
/ Diseases
for SUV420H1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SUV420H1 for disorders About GeneDecksing
OMIM gene information: 610881
OMIM disorders: --
2  diseases for SUV420H1: About MalaCardshomocysteine breast cancer
Human Genome Epidemiology (HuGE) Navigator: SUV420H1 (1 document)
Export disorders for SUV420H1 gene to outside databases
|
Publications
for SUV420H1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SUV420H1 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with SUV420H1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The sequence and gene characterization of a 400-kb candidate region for IDDM4 on chromosome 11q13. (PubMed id 11401438)1, 2, 3 Twells R.C....Hess J.F. (2001)
- Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.H....Lin W. (2000)
- Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins. (PubMed id 16322686)1, 2 Tryndyak V.P.... Pogribny I.P. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Comparative analyses of SUV420H1 isoforms and SUV420H 2 reveal differences in their cellular localization and effects on myogenic dif ferentiation. (PubMed id 21206904)1 Tsang L.W....Underhill D.A. (2010)
- Preferential dimethylation of histone H4 lysine 20 by Suv4-20. (PubMed id 18296440)1 Yang H....Mizzen C.A. (2008)
- GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression. (PubMed id 19074285)1 Chinenov Y....Rogatsky I. (2008)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M.... Figeys D. (2007)
|
External Searches for SUV420H1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SUV420H1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SUV420H1 gene
(According to HUGE)
About This Section
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Specialized Databases showing SUV420H1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for SUV420H1 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for SUV420H1 gene:
Search GeneIP for patents involving SUV420H1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SUV420H1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SUV420H1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SUV420H1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SUV420H1 | | | OriGene Protein Over-expression Lysate for SUV420H1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SUV420H1 | | OriGene 3'-UTR Clone for SUV420H1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUV420H1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUV420H1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SUV420H1 | | OriGene Custom Protein Services for SUV420H1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SUV420H1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SUV420H1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUV420H1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SUV420H1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUV420H1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUV420H1 |
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 | | | SUV420H1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUV420H1 |
|  |  |  | | | | Search ThermoFisher Antibodies for SUV420H1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUV420H1 |
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