SUSD5 Gene
protein-coding GIFtS : 41
GCID: GC03 M033167
sushi domain containing 5
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Aliasesfor SUSD5 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Sushi Domain Containing 5 1 2 KIAA05271 3 Sushi Domain-Containing Protein 52
Export aliases for SUSD5 gene to outside databases
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Summariesfor SUSD5 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor SUSD5 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000003.11 NC_018914.1 NT_022517.18 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SUSD5 gene promoter: E2F-3a E2F-4 Egr-3 E2F-5 p53 Evi-1 YY1 POU2F1 POU2F1a ZID Other transcription factors Search SABiosciences Chromatin IP Primers for SUSD5 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat SUSD5
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 3p22.3 Ensembl cytogenetic band: 3p22.3 HGNC cytogenetic band: 3p23 SUSD5 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 3 GeneLoc Exon Structure
GeneLoc location for GC03M033167: view genomic region
(about GC identifiers )
Start:
33,191,537 bp from pter
End:
33,260,707 bp from pter
Size:
69,171 bases
Orientation:
minus strand
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Proteinsfor SUSD5 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: SUSD5_HUMAN, O60279 (See
protein sequence )Recommended Name: Sushi domain-containing protein 5 precursor Size : 629 amino acids; 68021 Da
Subcellular location : Membrane; Single-pass type I membrane protein
Sequence caution : Sequence=BAA25453.1; Type=Erroneous initiation;Explore the universe of human proteins at neXtProt for SUSD5: NX_O60279 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_O60279 SUSD5 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_056366.1 ENSEMBL proteins: ENSP00000308727 ENSP00000406475 Human Recombinant Protein Products: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0016021 integral to membrane
IEA --
SUSD5 for ontologies About GeneDecksing SUSD5 Antibody Products: Assay Products for SUSD5:
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Protein
Domains / Familiesfor SUSD5 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
SUSD5 for domains About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry O60279 ProtoNet protein and cluster: O60279
2 Blocks protein families : IPB000436 Sushi domain/SCR domain/CCP module IPB000538 Link domain UniProtKB/Swiss-Prot: SUSD5_HUMAN, O60279 Similarity : Contains 1 Link domainSimilarity : Contains 1 Sushi (CCP/SCR) domain
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Functionfor SUSD5 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for SUSD5 (see all 2 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for SUSD5 (see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: SUSD5 (NM_015551 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SUSD5 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SUSD5
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUSD5
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005540 hyaluronic acid binding
IEA --
SUSD5 for ontologies About GeneDecksing
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Pathways & Interactionsfor SUSD5 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SUSD5 Gene Ontology (GO): 1 biological process term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0007155 cell adhesion
IEA --
SUSD5 for ontologies About GeneDecksing
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Drugs & Compoundsfor SUSD5 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for SUSD5 1 HMDB Compound for SUSD5 About this table Search CenterWatch for drugs/clinical trials and news about SUSD5
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Transcriptsfor SUSD5 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for SUSD5 gene: NM_015551.1 Unigene Cluster for SUSD5:
Sushi domain containing 5 Hs.196647 [show with all ESTs ] Unigene Representative Sequence: NM_015551 2 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000309558 (uc003cfo.1 ) ENST00000412539 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for SUSD5 (see all 2 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for SUSD5 (see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: SUSD5 (NM_015551 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SUSD5 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SUSD5
Additional cDNA sequence: AB011099.1 AK295869.1
1 DOTS entry : DT.100663935
24 AceView cDNA sequences :
CA412022 AI246355 AI356230 BQ003608 AI754284 BE327664 BX480913 BF195978 BX955611 CA436892 BG927695 AB011099 CD517021 CB963861 CB962537 BU193575 CA436560 BM806374 H84796 D63053 BM986927 CD250384 AW450421 BF977837 GeneLoc Exon Structure 2 Alternative Splicing Database (ASD) splice patterns (SP) for SUSD5 About this scheme ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b SP1 :               SP2 :         -      
ECgene alternative splicing isoforms for SUSD5
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Expression for SUSD5 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section SUSD5 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AAAATTGGGG
About this image SUSD5 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See SUSD5 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SUSD5 SOURCE GeneReport for Unigene cluster: Hs.196647 SABiosciences Custom PCR Arrays for SUSD5 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for SUSD5Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat SUSD5 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat SUSD5 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat SUSD5 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUSD5
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Orthologsfor SUSD5 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for SUSD5 gene from 3/9 species (see all 9 ) About this table
ENSEMBL Gene Tree for SUSD5 (if available)TreeFam Gene Tree for SUSD5 (if available)
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Paralogsfor SUSD5 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor SUSD5 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 3 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for SUSD5 (33191537 - 33260707 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for SUSD5: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing SUSD5
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Disorders
/ Diseasesfor SUSD5 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
SUSD5 for disorders About GeneDecksing 1 disease for SUSD5 : About MalaCards bone cancer Export disorders for SUSD5 gene to outside databases
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Publicationsfor SUSD5 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for SUSD5 gene integrated from 9 sources : (articles sorted by number of sources associating them with SUSD5) Utopia : connect your pdf to the dynamic world of online information
The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997) 1 , 2 Muzny D.M....Gibbs R.A. (2006) Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581) 1 , 2 Nagase T....Ohara O. (1998) Initial characterization of the human central proteome. (PubMed id 21269460) 2 Burkard T.R.... Colinge J. (2011)
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External Searches for SUSD5 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing SUSD5 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing SUSD5 gene
(According to HUGE )
About This Section
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Specialized Databases showing SUSD5 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for SUSD5 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for SUSD5 gene: Search GeneIP for patents involving SUSD5 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor SUSD5 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for SUSD5 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for SUSD5 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for SUSD5 OriGene Protein Over-expression Lysate for SUSD5 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for SUSD5 OriGene 3'-UTR Clone for SUSD5 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for SUSD5 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for SUSD5 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for SUSD5 OriGene Custom Protein Services for SUSD5 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SUSD5 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing SUSD5 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat SUSD5 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat SUSD5 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat SUSD5 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat SUSD5
Search Tocris compounds for SUSD5
SUSD5 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUSD5
Search ThermoFisher Antibodies for SUSD5
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SUSD5
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