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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SUSD4 Gene

protein-coding   GIFtS: 49
GCID: GC01M223394

Sushi Domain Containing 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Sushi Domain Containing 41 2
PRO2222
YHGM1962
Sushi Domain-Containing Protein 42

External Ids:    HGNC: 254701   Entrez Gene: 550612   Ensembl: ENSG000001435027   UniProtKB: Q5VX713   

Export aliases for SUSD4 gene to outside databases

Previous GC identifers: GC01M219767 GC01M221460 GC01M194069


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SUSD4 Gene: 
SUSD4 (sushi domain containing 4) is a protein-coding gene. Diseases associated with SUSD4 include fryns syndrome, and hepatitis b. An important paralog of this gene is KIAA0247.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_167186.1  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SUSD4 gene promoter:
         SRF   STAT1   AML1a   GATA-3   SRF (504 AA)   STAT1beta   STAT1alpha   GATA-1   GATA-2   Msx-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSUSD4 promoter sequence
   Search SABiosciences Chromatin IP Primers for SUSD4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUSD4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q41   Ensembl cytogenetic band:  1q41   HGNC cytogenetic band: 1q41

SUSD4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SUSD4 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M223394:  view genomic region     (about GC identifiers)

Start:
223,394,161 bp from pter      End:
223,537,544 bp from pter
Size:
143,384 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SUSD4_HUMAN, Q5VX71 (See protein sequence)
Recommended Name: Sushi domain-containing protein 4 precursor  
Size: 490 amino acids; 53778 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Secondary accessions: D3DTB9 Q6UX62 Q9BSR0 Q9NWG0
Alternative splicing: 4 isoforms:  Q5VX71-1   Q5VX71-2   Q5VX71-3   Q5VX71-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SUSD4: NX_Q5VX71

Explore proteomics data for SUSD4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5VX71

  • SUSD4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SUSD4 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001032252.1  NP_060452.3  

    ENSEMBL proteins: 
     ENSP00000344219   ENSP00000339926   ENSP00000340917   ENSP00000355843   ENSP00000399288  
     ENSP00000355842  

    Human Recombinant Protein Products for SUSD4: 
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    OriGene Protein Over-expression Lysate for SUSD4
    OriGene MassSpec for SUSD4 
    OriGene Custom Protein Services for SUSD4
    GenScript Custom Purified and Recombinant Proteins Services for SUSD4
    Novus Biologicals SUSD4 Protein
    Novus Biologicals SUSD4 Lysates
    Sino Biological Recombinant Protein for SUSD4
    Sino Biological Cell Lysate for SUSD4 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SUSD4 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--

    SUSD4 for ontologies           About GeneDecksing



    SUSD4 Antibody Products: 
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    Novus Biologicals SUSD4 Antibodies
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    ThermoFisher Antibodies for SUSD4
    LSBio Antibodies in human, mouse, rat for SUSD4 

    Assay Products for SUSD4: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for SUSD4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SUSD4 
    Cloud-Clone Corp. CLIAs for SUSD4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR000436 Sushi_SCR_CCP

    Graphical View of Domain Structure for InterPro Entry Q5VX71

    ProtoNet protein and cluster: Q5VX71

    1 Blocks protein domain: IPB000436 Sushi domain/SCR domain/CCP module

    UniProtKB/Swiss-Prot: SUSD4_HUMAN, Q5VX71
    Similarity: Contains 4 Sushi (CCP/SCR) domains


    SUSD4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Phenotypes:
         1 GenomeRNAi human phenotype for SUSD4:
     Elongated cells 

         1 MGI phenotypic allele for Susd4 (no phenotypes)

    SUSD4 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Susd4tm1Lex for SUSD4

       inGenious Targeting Laboratory - Custom generated mouse model solutions for SUSD4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SUSD4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SUSD4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SUSD4 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SUSD4
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate SUSD4:
    hsa-miR-622 hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidSUSD4 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SUSD4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SUSD4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SUSD4
    Sirion Biotech Customized adenovirus for overexpression of SUSD4

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for SUSD4 (see all 15)
    OriGene ORF clones in mouse, rat for SUSD4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SUSD4 (NM_017982)
    Sino Biological Human cDNA Clone for SUSD4
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SUSD4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUSD4
    Sirion Biotech Customized lentivirus for stable overexpression of SUSD4 
                         Customized lentivirus expression plasmids for stable overexpression of SUSD4 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SUSD4
    Search LifeMap BioReagents cell lines for SUSD4
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUSD4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SUSD4

    5/8 Interacting proteins for SUSD4 (Q5VX712, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK6Q166592, 3MINT-8277455 I2D: score=1 
    ENSG00000230463P794833I2D: score=1 
    ENSG00000231679P794833I2D: score=1 
    HLA-DRB3P794833I2D: score=1 
    COPS6Q7L5N13I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SUSD4

    Search CenterWatch for drugs/clinical trials and news about SUSD4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SUSD4 gene (2 alternative transcripts): 
    NM_001037175.2  NM_017982.3  

    Unigene Cluster for SUSD4:

    Sushi domain containing 4
    Hs.497841  [show with all ESTs]
    Unigene Representative Sequence: AK096265
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000343846(uc001hnx.3) ENST00000494793 ENST00000478605 ENST00000483818
    ENST00000484503 ENST00000470249 ENST00000484758 ENST00000344029(uc001hnz.2)
    ENST00000497669 ENST00000342943 ENST00000366878(uc001hny.4 uc010puw.2 uc010pux.1)
    ENST00000454695 ENST00000366877
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SUSD4
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate SUSD4:
    hsa-miR-622 hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidSUSD4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SUSD4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SUSD4
    Clone
    Products:
         
    OriGene clones in human, mouse for SUSD4 (see all 15)
    OriGene ORF clones in mouse, rat for SUSD4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SUSD4 (NM_017982)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SUSD4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUSD4
    Sirion Biotech Customized lentivirus for stable overexpression of SUSD4 
                         Customized lentivirus expression plasmids for stable overexpression of SUSD4 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SUSD4
    OriGene qSTAR qPCR primer pairs in human, mouse for SUSD4
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SUSD4
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUSD4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUSD4

    Additional mRNA sequence: 

    AK000914.1 AK096265.1 AK295553.1 AK296923.1 AY358495.1 BC004888.2 EF560748.1 

    12 DOTS entries:

    DT.100749746  DT.40127876  DT.411506  DT.40127212  DT.100675234  DT.91713619  DT.91888592  DT.97796827 
    DT.121337348  DT.91661507  DT.92051348  DT.99933510 

    24/99 AceView cDNA sequences (see all 99):

    BE744704 AI628101 BQ045203 BE644888 BQ614040 AW204351 AK000914 BE503579 
    BQ128216 AI090524 AI701529 BM840961 AI984400 NM_017982 AA335726 AA988038 
    CA942864 F12032 AI538781 AI417581 BE671439 BP360736 BM849437 BC004888 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SUSD4 expression in normal human tissues (normalized intensities)      SUSD4 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGATCTGTG
    SUSD4 Expression
    About this image


    SUSD4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Ovary (Reproductive System)
             Granulosa Cells Primary Follicle
     
     Liver (Hepatobiliary System)
             Perivenous Hepatocytes Liver Lobule
     
     Epithelium (Uncategorized)
             gingival epithelium   
     
     Brain (Nervous System)
             Oligodendrocyte Precursor Cells Forebrain White Matter
     
     Oral Cavity (Gastrointestinal Tract)
             gingival epithelium   

    See SUSD4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SUSD4

    SOURCE GeneReport for Unigene cluster: Hs.497841
        SABiosciences Custom PCR Arrays for SUSD4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for SUSD4
    OriGene qSTAR qPCR primer pairs in human, mouse for SUSD4
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SUSD4
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUSD4
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUSD4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUSD4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for SUSD4 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Susd41 , 5 sushi domain containing 41, 5 88.71(n)1
    91.22(a)1
      1 (85.94 cM)5
    969351  NM_144796.41  NP_659045.21 
     1827638605 
    chicken
    (Gallus gallus)
    Aves SUSD41 sushi domain containing 4 73.32(n)
    73.7(a)
      770442  XM_001233776.2  XP_001233777.2 
    lizard
    (Anolis carolinensis)
    Reptilia SUSD46
    sushi domain containing 4
    73(a)
    1 ↔ 1
    1(244765838-244943118)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5603041 sushi domain-containing protein 4-like 63.3(n)
    58.92(a)
      560304  XM_683701.2  XP_688793.1 


    ENSEMBL Gene Tree for SUSD4 (if available)
    TreeFam Gene Tree for SUSD4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SUSD4 gene
    KIAA02472  
    1 SIMAP similar gene for SUSD4 using alignment to 4 protein entries:     SUSD4_HUMAN (see all proteins):
    KIAA0247

    SUSD4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2581 SNPs in SUSD4 are shown (see all 2581)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1843349861,2
    --223393694(+) AAACAC/TCCTAA 1 -- int10--------
    rs1510715141,2
    --223393804(+) GATATG/TCTATA 1 -- int10--------
    rs8511531,2
    C,F,H--223393826(-) tcttaG/Ctccac 1 -- int117Minor allele frequency- C:0.03NS EA NA WA 2016
    rs1409230011,2
    C--223393861(+) TGCTGC/TGGGCT 1 -- int10--------
    rs1159478951,2
    C,F--223393870(+) CTGGAG/TAGGCA 1 -- int11Minor allele frequency- T:0.01NA 120
    rs1889239281,2
    --223393891(+) TGGTCC/TGCCAG 1 -- int10--------
    rs8511521,2
    C,F,H--223394018(-) TGGAGG/ATTGTC 1 -- int123Minor allele frequency- A:0.02NS EA NA WA 2230
    rs1820084271,2
    --223394068(+) TCTCTA/TGTTCT 1 -- int10--------
    rs1147375941,2
    F--223394119(+) CACCCC/TACTCC 1 -- int11Minor allele frequency- T:0.02WA 118
    rs798359641,2
    F--223394134(+) CACCCG/AACTCT 1 -- int11Minor allele frequency- A:0.01WA 118

    HapMap Linkage Disequilibrium report for SUSD4 (223394161 - 223537544 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for SUSD4:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv826809CNV Gain20364138
    nsv518979CNV Gain19592680
    nsv516810CNV Gain19592680
    nsv832659CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SUSD4
    DNA2.0 Custom Variant and Variant Library Synthesis for SUSD4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    3 diseases for SUSD4:    About MalaCards
    fryns syndrome    hepatitis b    hepatitis


    SUSD4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SUSD4
    Human Genome Epidemiology (HuGE) Navigator: SUSD4 (1 document)

    Export disorders for SUSD4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SUSD4 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with SUSD4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    4. Sushi domain-containing protein 4 (SUSD4) inhibits com plement by disrupting the formation of the classical C3 convertase. (PubMed id 23482636)1 Holmquist E....Blom A.M. (2013)
    5. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
    6. Tissue distribution and functional analysis of Sushi domain-containing protein 4. (PubMed id 20348246)1 Tu Z....Lin F. (2010)
    7. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (2007)
    8. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PubMed id 17903293)4 Benjamin E.J....Vasan R.S. (2007)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55061 HGNC: 25470 AceView: FLJ10052 Ensembl:ENSG00000143502 euGenes: HUgn55061
    ECgene: SUSD4 H-InvDB: SUSD4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SUSD4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SUSD4 gene:
    Search GeneIP for patents involving SUSD4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Regulatory tfbs in SUSD4 promoter
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     Proteins for SUSD4
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     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUSD4
     inGenious Targeting Laboratory - Custom generated mouse model solutions for SUSD4
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
    transforming growth factor, beta 1
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