Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SUSD4 Gene

protein-coding   GIFtS: 49
GCID: GC01M223394

Sushi Domain Containing 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Sushi Domain Containing 41 2
PRO2222
YHGM1962
Sushi Domain-Containing Protein 42

External Ids:    HGNC: 254701   Entrez Gene: 550612   Ensembl: ENSG000001435027   UniProtKB: Q5VX713   

Export aliases for SUSD4 gene to outside databases

Previous GC identifers: GC01M219767 GC01M221460 GC01M194069


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for SUSD4 Gene:
SUSD4 (sushi domain containing 4) is a protein-coding gene. Diseases associated with SUSD4 include fryns syndrome, and gingivitis. An important paralog of this gene is KIAA0247.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000001.11  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SUSD4 gene promoter:
         SRF   STAT1   AML1a   GATA-3   SRF (504 AA)   STAT1beta   STAT1alpha   GATA-1   GATA-2   Msx-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSUSD4 promoter sequence
   Search Chromatin IP Primers for SUSD4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SUSD4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q41   Ensembl cytogenetic band:  1q41   HGNC cytogenetic band: 1q41

SUSD4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SUSD4 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M223394:  view genomic region     (about GC identifiers)

Start:
223,394,161 bp from pter      End:
223,537,544 bp from pter
Size:
143,384 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SUSD4_HUMAN, Q5VX71 (See protein sequence)
Recommended Name: Sushi domain-containing protein 4 precursor  
Size: 490 amino acids; 53778 Da
Secondary accessions: D3DTB9 Q6UX62 Q9BSR0 Q9NWG0
Alternative splicing: 4 isoforms:  Q5VX71-1   Q5VX71-2   Q5VX71-3   Q5VX71-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SUSD4: NX_Q5VX71

Explore proteomics data for SUSD4 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn104, Asn134, Asn192

  • See SUSD4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001032252.1  NP_060452.3  

    ENSEMBL proteins: 
     ENSP00000344219   ENSP00000477374   ENSP00000476954   ENSP00000477432   ENSP00000339926  
     ENSP00000355843   ENSP00000399288   ENSP00000355842  

    SUSD4 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for SUSD4
    OriGene Protein Over-expression Lysate for SUSD4
    OriGene MassSpec for SUSD4
    OriGene Custom Protein Services for SUSD4
    GenScript Custom Purified and Recombinant Proteins Services for SUSD4
    Novus Biologicals SUSD4 Protein
    Novus Biologicals SUSD4 Lysates
    Sino Biological Recombinant Protein for SUSD4
    Sino Biological Cell Lysate for SUSD4
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SUSD4

    SUSD4 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SUSD4
    Novus Biologicals SUSD4 Antibodies
    Abcam antibodies for SUSD4
    Cloud-Clone Corp. Antibodies for SUSD4
    ThermoFisher Antibodies for SUSD4
    LSBio Antibodies in human, mouse, rat for SUSD4

    SUSD4 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SUSD4
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SUSD4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SUSD4
    Cloud-Clone Corp. CLIAs for SUSD4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR000436 Sushi_SCR_CCP

    Graphical View of Domain Structure for InterPro Entry Q5VX71

    ProtoNet protein and cluster: Q5VX71

    1 Blocks protein domain: IPB000436 Sushi domain/SCR domain/CCP module

    UniProtKB/Swiss-Prot: SUSD4_HUMAN, Q5VX71
    Similarity: Contains 4 Sushi (CCP/SCR) domains


    SUSD4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Phenotypes:
         1 GenomeRNAi human phenotype for SUSD4:
     Elongated cells 

         1 MGI phenotypic allele for Susd4 (no phenotypes)

    SUSD4 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Susd4tm1Lex for SUSD4

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SUSD4
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SUSD4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SUSD4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SUSD4

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SUSD4 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate SUSD4:
    hsa-miR-622 hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidSUSD4 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SUSD4
    Predesigned siRNA for gene silencing in human, mouse, rat SUSD4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SUSD4

    Clone
    Products:
         
    OriGene clones in human, mouse for SUSD4 (see all 14)
    OriGene ORF clones in mouse, rat for SUSD4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SUSD4 (NM_017982)
    Sino Biological Human cDNA Clone for SUSD4
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SUSD4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUSD4

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SUSD4
    Browse ESI BIO Cell Lines and PureStem Progenitors for SUSD4 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUSD4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    SUSD4_HUMAN, Q5VX71: Membrane; Single-pass type I membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    SUSD4 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SUSD4
    Interactions:

        Search GeneGlobe Interaction Network for SUSD4

    Selected Interacting proteins for SUSD4 (Q5VX712, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK6Q166592, 3MINT-8277455 I2D: score=1 
    ENSG00000196101P794833I2D: score=1 
    HLA-DRB3P794833I2D: score=1 
    COPS6Q7L5N13I2D: score=1 
    NAT6Q930153I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SUSD4



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SUSD4 gene (2 alternative transcripts): 
    NM_001037175.2  NM_017982.3  

    Unigene Cluster for SUSD4:

    Sushi domain containing 4
    Hs.497841  [show with all ESTs]
    Unigene Representative Sequence: AK096265
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000343846(uc001hnx.3) ENST00000484758 ENST00000494793 ENST00000478605
    ENST00000608996 ENST00000483818 ENST00000484503 ENST00000470249 ENST00000344029(uc001hnz.2)
    ENST00000497669 ENST00000342943 ENST00000366878(uc001hny.4 uc010puw.2 uc010pux.1)
    ENST00000454695 ENST00000366877
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SUSD4 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate SUSD4:
    hsa-miR-622 hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidSUSD4 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SUSD4
    Predesigned siRNA for gene silencing in human, mouse, rat SUSD4
    Clone
    Products:
         
    OriGene clones in human, mouse for SUSD4 (see all 14)
    OriGene ORF clones in mouse, rat for SUSD4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SUSD4 (NM_017982)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SUSD4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUSD4
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SUSD4
    OriGene qSTAR qPCR primer pairs in human, mouse for SUSD4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SUSD4
      QuantiTect SYBR Green Assays in human, mouse, rat SUSD4
      QuantiFast Probe-based Assays in human, mouse, rat SUSD4

    Additional mRNA sequence: 

    AK000914.1 AK096265.1 AK295553.1 AK296923.1 AY358495.1 BC004888.2 EF560748.1 

    12 DOTS entries:

    DT.100749746  DT.40127876  DT.411506  DT.40127212  DT.100675234  DT.91713619  DT.91888592  DT.97796827 
    DT.121337348  DT.91661507  DT.92051348  DT.99933510 

    Selected AceView cDNA sequences (see all 99):

    AA418002 BF447665 BQ128216 AW204351 BE744704 AI538781 BC004888 AA335726 
    BP360736 AA988038 BQ614040 NM_017982 BX372016 AK000914 AI417581 AI628101 
    BM311465 BE671439 AI701529 BE644888 BQ045203 AI090524 CA942864 F12032 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SUSD4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGATCTGTG
    SUSD4 Expression
    About this image


    SUSD4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Ovary (Reproductive System)
             Granulosa Cells Primary Follicle
     
     Testis (Reproductive System)
             Sertoli cells Seminiferous Tubules
     
     Liver (Hepatobiliary System)
             Perivenous Hepatocytes Liver Lobule
     
     Brain (Nervous System)
             Oligodendrocyte Precursor Cells Forebrain White Matter
    SUSD4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SUSD4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.497841
        Custom PCR Arrays for SUSD4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for SUSD4
    OriGene qSTAR qPCR primer pairs in human, mouse for SUSD4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SUSD4
    QuantiTect SYBR Green Assays in human, mouse, rat SUSD4
    QuantiFast Probe-based Assays in human, mouse, rat SUSD4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUSD4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for SUSD4 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Susd41 , 5 sushi domain containing 41, 5 88.71(n)1
    91.22(a)1
      1 (85.94 cM)5
    969351  NM_144796.41  NP_659045.21 
     1827638605 
    chicken
    (Gallus gallus)
    Aves SUSD41 sushi domain containing 4 73.26(n)
    73.64(a)
      770442  XM_001233776.3  XP_001233777.3 
    lizard
    (Anolis carolinensis)
    Reptilia SUSD46
    sushi domain containing 4
    72(a)
    1 ↔ 1
    1(244765838-244943118)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tlr51 toll-like receptor 5 68.57(n)
    63.3(a)
      779812  NM_001078891.1  NP_001072359.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5603041 sushi domain-containing protein 4-like 63.27(n)
    59.72(a)
      560304  XM_683701.3  XP_688793.1 


    ENSEMBL Gene Tree for SUSD4 (if available)
    TreeFam Gene Tree for SUSD4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for SUSD4 gene
    KIAA02472  
    1 SIMAP similar gene for SUSD4 using alignment to 7 protein entries:     SUSD4_HUMAN (see all proteins):
    KIAA0247

    SUSD4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SUSD4 (see all 2581)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1843349861,2
    --223393694(+) AAACAC/TCCTAA 1 -- int10--------
    rs1510715141,2
    --223393804(+) GATATG/TCTATA 1 -- int10--------
    rs8511531,2
    C,F,H--223393826(-) tcttaG/Ctccac 1 -- int117Minor allele frequency- C:0.03NS EA NA WA 2016
    rs1409230011,2
    C--223393861(+) TGCTGC/TGGGCT 1 -- int10--------
    rs1159478951,2
    C,F--223393870(+) CTGGAG/TAGGCA 1 -- int11Minor allele frequency- T:0.01NA 120
    rs1889239281,2
    --223393891(+) TGGTCC/TGCCAG 1 -- int10--------
    rs8511521,2
    C,F,H--223394018(-) TGGAGG/ATTGTC 1 -- int123Minor allele frequency- A:0.02NS EA NA WA 2230
    rs1820084271,2
    --223394068(+) TCTCTA/TGTTCT 1 -- int10--------
    rs1147375941,2
    F--223394119(+) CACCCC/TACTCC 1 -- int11Minor allele frequency- T:0.02WA 118
    rs798359641,2
    F--223394134(+) CACCCG/AACTCT 1 -- int11Minor allele frequency- A:0.01WA 118

    HapMap Linkage Disequilibrium report for SUSD4 (223394161 - 223537544 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for SUSD4:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv826809CNV Gain20364138
    nsv518979CNV Gain19592680
    nsv516810CNV Gain19592680
    nsv832659CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SUSD4
    DNA2.0 Custom Variant and Variant Library Synthesis for SUSD4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    4 diseases for SUSD4:    
    About MalaCards
    fryns syndrome    gingivitis    hepatitis b    hepatitis


    SUSD4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SUSD4
    Human Genome Epidemiology (HuGE) Navigator: SUSD4 (1 document)

    Export disorders for SUSD4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SUSD4 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with SUSD4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    4. Sushi domain-containing protein 4 (SUSD4) inhibits complement by disrupting the formation of the classical C3 convertase. (PubMed id 23482636)1 Holmquist E....Blom A.M. (FASEB J. 2013)
    5. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)
    6. Tissue distribution and functional analysis of Sushi domain-containing protein 4. (PubMed id 20348246)1 Tu Z....Lin F. (Am. J. Pathol. 2010)
    7. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    8. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PubMed id 17903293)4 Benjamin E.J....Vasan R.S. (BMC Med. Genet. 2007)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 55061 HGNC: 25470 AceView: FLJ10052 Ensembl:ENSG00000143502 euGenes: HUgn55061
    ECgene: SUSD4 H-InvDB: SUSD4

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SUSD4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SUSD4 gene:
    Search GeneIP for patents involving SUSD4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SUSD4  
     OriGene qPCR primer pairs and template standards for SUSD4   OriGene Protein Over-expression Lysate for SUSD4  
     OriGene MassSpec something-or-other for SUSD4   OriGene clones in human, mouse for SUSD4  
     OriGene qSTAR qPCR primer pairs in human, mouse for SUSD4   OriGene Purified Protein for SUSD4  
     OriGene ORF clones in mouse, rat for SUSD4   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SUSD4   OriGene Custom Protein Services for SUSD4  

     
     
     Block miRNA regulation of human, mouse, rat SUSD4 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SUSD4
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SUSD4 Predesigned siRNA for gene silencing in human, mouse, rat SUSD4
     QuantiFast Probe-based Assays in human, mouse, rat SUSD4 QuantiTect SYBR Green Assays in human, mouse, rat SUSD4
     Custom PCR Arrays for SUSD4 Search Chromatin IP Primers for SUSD4
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SUSD4  Search GeneGlobe Interaction Network for SUSD4
     Regulatory tfbs in SUSD4 promoter
     GenScript Custom Purified and Recombinant Proteins Services for SUSD4 GenScript cDNA clones with any tag delivered in your preferred vector for SUSD4
     GenScript Custom Assay Services for SUSD4 GenScript Custom overexpressing Cell Line Services for SUSD4
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SUSD4
     Proteins for SUSD4
     Cell Lysates for SUSD4
     cDNA Clones for SUSD4
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SUSD4 antibodies
     SUSD4 proteins
     SUSD4 lysates
     Antibodies for SUSD4
     See all of Abcam's Antibodies, Kits and Proteins for SUSD4
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SUSD4
     Antibodies for SUSD4
     ELISAs for SUSD4
     CLIAs for SUSD4



     Browse ESI BIO Cell Lines and PureStem Progenitors for SUSD4
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUSD4
     SwitchGear 3'UTR luciferase reporter plasmids for SUSD4
     SwitchGear Promoter luciferase reporter plasmids for SUSD4
     ThermoFisher Antibodies for SUSD4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUSD4
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SUSD4
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SUSD4
     LSBio Antibodies in human, mouse, rat for SUSD4
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SUSD4 gene at Home site.
    Version: 3.12.142 28 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4