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Aliases for SUSD1 Gene

Aliases for SUSD1 Gene

  • Sushi Domain Containing 1 2 3

External Ids for SUSD1 Gene

Summaries for SUSD1 Gene

GeneCards Summary for SUSD1 Gene

SUSD1 (Sushi Domain Containing 1) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SUSD1 Gene

Genomics for SUSD1 Gene

Genomic Location for SUSD1 Gene

Start:
112,040,781 bp from pter
End:
112,175,408 bp from pter
Size:
134,628 bases
Orientation:
Minus strand

Genomic View for SUSD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SUSD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SUSD1 Gene

Regulatory Elements for SUSD1 Gene

Proteins for SUSD1 Gene

  • Protein details for SUSD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UWL2-SUSD1_HUMAN
    Recommended name:
    Sushi domain-containing protein 1
    Protein Accession:
    Q6UWL2
    Secondary Accessions:
    • A1A4C5
    • A8KA03
    • Q5T8V6
    • Q5T8V7
    • Q6P9G7
    • Q8WU83
    • Q96DM9
    • Q9H6V2
    • Q9NTA7

    Protein attributes for SUSD1 Gene

    Size:
    747 amino acids
    Molecular mass:
    82710 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB15149.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB71259.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAI12348.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI95300.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for SUSD1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SUSD1 Gene

Proteomics data for SUSD1 Gene at MOPED

Post-translational modifications for SUSD1 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys686
  • Glycosylation at Asn87, Asn112, Asn193, Asn253, Asn308, Asn348, Asn367, and Asn563

No data available for DME Specific Peptides for SUSD1 Gene

Domains for SUSD1 Gene

Suggested Antigen Peptide Sequences for SUSD1 Gene

Graphical View of Domain Structure for InterPro Entry

Q6UWL2

UniProtKB/Swiss-Prot:

SUSD1_HUMAN
Domain:
  • Contains 3 EGF-like domains.:
    • Q6UWL2
  • Contains 2 Sushi (CCP/SCR) domains.:
    • Q6UWL2
genes like me logo Genes that share domains with SUSD1: view

No data available for Gene Families for SUSD1 Gene

Function for SUSD1 Gene

Gene Ontology (GO) - Molecular Function for SUSD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005509 calcium ion binding IEA --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with SUSD1: view

miRNA for SUSD1 Gene

miRTarBase miRNAs that target SUSD1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SUSD1 Gene

Localization for SUSD1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SUSD1 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SUSD1 Gene COMPARTMENTS Subcellular localization image for SUSD1 gene
Compartment Confidence
plasma membrane 3
cytoskeleton 1
endoplasmic reticulum 1
extracellular 1
golgi apparatus 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for SUSD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SUSD1: view

Pathways for SUSD1 Gene

SuperPathways for SUSD1 Gene

No Data Available

Interacting Proteins for SUSD1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000363388%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000275493%0d%0a
Selected Interacting proteins: Q6UWL2-SUSD1_HUMAN ENSP00000363388 for SUSD1 Gene via MINT STRING I2D

Gene Ontology (GO) - Biological Process for SUSD1 Gene

None

No data available for Pathways by source for SUSD1 Gene

Transcripts for SUSD1 Gene

Unigene Clusters for SUSD1 Gene

Sushi domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SUSD1 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b
SP1: - - - -
SP2: - - - - -
SP3: - - - - - -
SP4: - -
SP5: -
SP6:
SP7: - -

Relevant External Links for SUSD1 Gene

GeneLoc Exon Structure for
SUSD1
ECgene alternative splicing isoforms for
SUSD1

Expression for SUSD1 Gene

mRNA expression in normal human tissues for SUSD1 Gene

mRNA differential expression in normal tissues according to GTEx for SUSD1 Gene

This gene is overexpressed in Whole Blood (5.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SUSD1 Gene

SOURCE GeneReport for Unigene cluster for SUSD1 Gene Hs.494827

genes like me logo Genes that share expressions with SUSD1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SUSD1 Gene

Orthologs for SUSD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SUSD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SUSD1 35
  • 94.42 (n)
  • 93.51 (a)
SUSD1 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SUSD1 35
  • 85.5 (n)
  • 80.72 (a)
SUSD1 36
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SUSD1 35
  • 84.39 (n)
  • 80.41 (a)
SUSD1 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Susd1 35
  • 80.95 (n)
  • 74.93 (a)
Susd1 16
Susd1 36
  • 74 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SUSD1 36
  • 57 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 65 (a)
OneToMany
-- 36
  • 65 (a)
OneToMany
-- 36
  • 49 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Susd1 35
  • 76.24 (n)
  • 67.09 (a)
chicken
(Gallus gallus)
Aves SUSD1 35
  • 58.67 (n)
  • 50.82 (a)
SUSD1 36
  • 46 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SUSD1 36
  • 42 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia MGC75573 35
susd1 35
  • 49.36 (n)
  • 34.9 (a)
zebrafish
(Danio rerio)
Actinopterygii SUSD1 (1 of 3) 36
  • 33 (a)
OneToMany
SUSD1 (2 of 3) 36
  • 33 (a)
OneToMany
SUSD1 (3 of 3) 36
  • 29 (a)
OneToMany
Species with no ortholog for SUSD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SUSD1 Gene

ENSEMBL:
Gene Tree for SUSD1 (if available)
TreeFam:
Gene Tree for SUSD1 (if available)

Paralogs for SUSD1 Gene

Selected SIMAP similar genes for SUSD1 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with SUSD1: view

No data available for Paralogs for SUSD1 Gene

Variants for SUSD1 Gene

Sequence variations from dbSNP and Humsavar for SUSD1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs700097 -- 112,146,879(+) gatcc(C/T)ccagc intron-variant
rs700098 -- 112,144,851(-) TATAC(C/T)TGCTG intron-variant
rs700100 -- 112,129,862(-) ATATC(A/G)TAGCA intron-variant
rs700101 -- 112,132,497(+) AAGTC(A/T)CTAGC intron-variant
rs700102 -- 112,132,980(+) GTTAT(A/G)Cagca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SUSD1 Gene

Variant ID Type Subtype PubMed ID
nsv893731 CNV Gain 21882294
esv2555427 CNV Insertion 19546169
esv268057 CNV Insertion 20981092
esv272517 CNV Insertion 20981092
esv1083675 CNV Insertion 17803354
esv2552622 CNV Deletion 19546169
esv2180224 CNV Deletion 18987734
esv2738945 CNV Deletion 23290073
esv2675703 CNV Deletion 23128226
nsv415911 CNV Loss 16902084

Relevant External Links for SUSD1 Gene

HapMap Linkage Disequilibrium report
SUSD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SUSD1 Gene

Disorders for SUSD1 Gene

Relevant External Links for SUSD1

Genetic Association Database (GAD)
SUSD1
Human Genome Epidemiology (HuGE) Navigator
SUSD1
genes like me logo Genes that share disorders with SUSD1: view

No data available for UniProtKB/Swiss-Prot for SUSD1 Gene

Publications for SUSD1 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach. (PMID: 16263699) Lewandrowski U. … Sickmann A. (Mol. Cell. Proteomics 2006) 3 4

Products for SUSD1 Gene

Sources for SUSD1 Gene

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