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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SURF4 Gene

protein-coding   GIFtS: 53
GCID: GC09M136228

Surfeit 4

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Surfeit 41 2
Surface 4 Integral Membrane Protein1 2
Surfeit Locus Protein 41 2
ERV292
SURF-43

External Ids:    HGNC: 114761   Entrez Gene: 68362   Ensembl: ENSG000001482487   OMIM: 1856605   UniProtKB: O152603   

Export aliases for SURF4 gene to outside databases

Previous GC identifers: GC09M127318 GC09M127785 GC09M129582 GC09M131504 GC09M133257 GC09M135206 GC09M135218 GC09M105728


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SURF4 Gene:
This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes
that do not share sequence similarity. The encoded protein is a conserved integral membrane protein that
interacts with endoplasmic reticulum-Golgi intermediate compartment proteins. Disruption of this gene results in
reduced numbers of endoplasmic reticulum-Golgi intermediate compartment clusters and redistribution of coat
protein I to the cytosol. Alternate splicing results in multiple transcript variants. (provided by RefSeq, Jul
2013)

GeneCards Summary for SURF4 Gene: 
SURF4 (surfeit 4) is a protein-coding gene. Diseases associated with SURF4 include paraplegia. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: SURF4_HUMAN, O15260
Function: May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate
compartment and of the Golgi

Gene Wiki entry for SURF4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NT_035014.4  NC_018920.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SURF4 gene promoter:
         AML1a   Lmo2   STAT5A   Nkx2-5   C/EBPalpha   HEN1   CHOP-10   ZID   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSURF4 promoter sequence
   Search SABiosciences Chromatin IP Primers for SURF4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SURF4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.2   Ensembl cytogenetic band:  9q34.2   HGNC cytogenetic band: 9q33-q34

SURF4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SURF4 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M136228:  view genomic region     (about GC identifiers)

Start:
136,228,325 bp from pter      End:
136,242,970 bp from pter
Size:
14,646 bases      Orientation:
minus strand

1 alternative location:
Chr9-,NW_003315925 187,558-202,193     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SURF4_HUMAN, O15260 (See protein sequence)
Recommended Name: Surfeit locus protein 4  
Size: 269 amino acids; 30394 Da
Subunit: Found in a complex composed at least of SURF4, TMED2 and TMED10. May interact with LMAN1
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi
intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane
protein. Note=Cycles between the endoplasmic reticulum and the Golgi
Secondary accessions: O60923 Q5T8U6 Q9UNZ0 Q9UNZ1
Alternative splicing: 2 isoforms:  O15260-1   O15260-2   

Explore the universe of human proteins at neXtProt for SURF4: NX_O15260

Explore proteomics data for SURF4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O15260

  • SURF4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SURF4 Protein Expression
    REFSEQ proteins (7 alternative transcripts): 
    NP_001267717.1  NP_001267718.1  NP_001267719.1  NP_001267720.1  NP_001267721.1  NP_001267722.1  NP_149351.1  

    ENSEMBL proteins: 
     ENSP00000361057   ENSP00000419853   ENSP00000361059   ENSP00000446061  

    Human Recombinant Protein Products for SURF4: 
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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for SURF4 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0005793endoplasmic reticulum-Golgi intermediate compartment IDA15308636
    GO:0016021integral to membrane IEA--
    GO:0033116endoplasmic reticulum-Golgi intermediate compartment membrane IEA--

    SURF4 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR002995 Surf4

    Graphical View of Domain Structure for InterPro Entry O15260

    ProtoNet protein and cluster: O15260

    2 Blocks protein domains:
    IPB002995 Surf4 protein
    IPB011592 Surfeit locus 4-related


    UniProtKB/Swiss-Prot: SURF4_HUMAN, O15260
    Domain: The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins
    Similarity: Belongs to the SURF4 family


    SURF4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SURF4_HUMAN, O15260
    Function: May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate
    compartment and of the Golgi

         Genatlas biochemistry entry for SURF4:
    surfeit 4 (see SURF@),putative integral membrane protein of the endoplasmic reticulum,30kDa

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18287528
         
    SURF4 for ontologies           About GeneDecksing


    Animal Models:
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    miRTarBase miRNAs that target SURF4:
    hsa-mir-124 (MIRT001831)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SURF4
    8/71 QIAGEN miScript miRNA Assays for microRNAs that regulate SURF4 (see all 71):
    hsa-miR-607 hsa-miR-1321 hsa-miR-1260b hsa-miR-128 hsa-miR-30d hsa-miR-371-5p hsa-miR-1244 hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidSURF4 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SURF4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/87 Interacting proteins for SURF4 (O152601, 3 ENSP000003610574) via UniProtKB, MINT, STRING, and/or I2D (see all 87)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TMEM173Q86WV61, 3, ENSP000003312884EBI-1044848,EBI-2800345 I2D: score=1 STRING: ENSP00000331288
    SEC61A1P616193, ENSP000002432534I2D: score=4 STRING: ENSP00000243253
    C20orf24Q9BUV83, ENSP000003412134I2D: score=2 STRING: ENSP00000341213
    DDOSTP396563, ENSP000003641884I2D: score=2 STRING: ENSP00000364188
    SERINC3Q135303, ENSP000002551754I2D: score=2 STRING: ENSP00000255175
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007030Golgi organization IMP18287528
    GO:0010638positive regulation of organelle organization IMP18287528
    GO:0032527NOT protein exit from endoplasmic reticulum IMP18287528
    GO:0034498NOT early endosome to Golgi transport IMP18287528

    SURF4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SURF4

    Search CenterWatch for drugs/clinical trials and news about SURF4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SURF4 gene (7 alternative transcripts): 
    NM_001280788.1  NM_001280789.1  NM_001280790.1  NM_001280791.1  NM_001280792.1  NM_001280793.1  NM_033161.3  

    Unigene Cluster for SURF4:

    Surfeit 4
    Hs.512465  [show with all ESTs]
    Unigene Representative Sequence: NM_033161
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371989(uc011mda.2 uc010nal.3 uc004cdj.3 uc011mdb.2 uc011mdc.2 uc011mdd.2)
    ENST00000485435 ENST00000465565 ENST00000467910 ENST00000371991 ENST00000371982
    ENST00000545297
    miRNA
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    8/71 QIAGEN miScript miRNA Assays for microRNAs that regulate SURF4 (see all 71):
    hsa-miR-607 hsa-miR-1321 hsa-miR-1260b hsa-miR-128 hsa-miR-30d hsa-miR-371-5p hsa-miR-1244 hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidSURF4 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AF078866.1 AF078867.1 AK026646.1 AK293434.1 AK295435.1 AK299656.1 AK300004.1 AK301737.1 
    AK303309.1 AK310333.1 AK315488.1 AK316480.1 BC018741.1 BC111023.1 BX647961.1 Y14820.1 

    24/60 DOTS entries (see all 60):

    DT.100753828  DT.100881736  DT.121151916  DT.100881739  DT.100881723  DT.121152226  DT.70101700  DT.95301849 
    DT.100881734  DT.95276102  DT.100881719  DT.121152066  DT.121152231  DT.100881716  DT.121151967  DT.100881738 
    DT.100881724  DT.95276105  DT.121151697  DT.100881708  DT.100881733  DT.121152095  DT.121151952  DT.95276119 

    24/1147 AceView cDNA sequences (see all 1147):

    AI783753 BM679581 BQ682491 AA458960 BM670271 AA313854 BU182777 CR610130 
    CA942044 BM553421 CD724142 BM754979 BQ028596 BI670332 CB140774 AW183550 
    AW009543 BG329697 BM556601 BM783666 BU552608 BM771551 AA490557 BC018741 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for SURF4 (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12a · 12b
    SP1:        -     -     -     -     -     -     -     -           -                       -                 -               
    SP2:                    -     -     -     -     -     -           -                       -                 -               
    SP3:                    -     -     -     -     -     -           -                       -                                 
    SP4:                                -           -     -           -                       -                                 
    SP5:                    -     -     -     -     -     -           -                                                         


    ECgene alternative splicing isoforms for SURF4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SURF4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGACTGGCT
    SURF4 Expression
    About this image


    See SURF4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SURF4

    SOURCE GeneReport for Unigene cluster: Hs.512465
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SURF4 gene from 8/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Surf41 , 5 surfeit gene 41, 5 90.21(n)1
    99.26(a)1
      2 (19.10 cM)5
    209321  NM_011512.31  NP_035642.11 
     269200405 
    chicken
    (Gallus gallus)
    Aves SURF41 surfeit 4 81.04(n)
    93.31(a)
      374273  NM_204355.1  NP_989686.1 
    lizard
    (Anolis carolinensis)
    Reptilia SURF46
    Uncharacterized protein
    80(a)
    1 ↔ 1
    2(28996709-29017143)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.334202 Xenopus laevis transcribed sequence with strong similarity more 79.4(n)    BU909982.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc658062 similar to surfeit 4 80.12(n)   394102  BC056295.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Surf41 , 3 Surfeit 41 59(a)3
    64.41(n)1
    59.77(a)1
      88F13
    418641  NM_057874.41  NP_477222.11 
    worm
    (Caenorhabditis elegans)
    Secernentea sft-41 , 3 Protein SFT-41 58(a)
    (best of 2)3
    60.07(n)1
    58.96(a)1
      X(5814578-5815981)3
    1808431  NM_076569.71  NP_508970.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ERV29(YGR284C)4
    ERV291
    Protein localized to COPII-coated vesicles, involved more4
    Erv29p1
    45.83(n)1
    37.08(a)1
      7(1061590-1060658)4
    8532011, 4  NP_011800.31  NP_011800.14 


    ENSEMBL Gene Tree for SURF4 (if available)
    TreeFam Gene Tree for SURF4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/323 SNPs in SURF4 are shown (see all 323)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1413355451,2
    --136228606(+) CTGGTA/GCAGAA 1 -- ut310--------
    rs21073681,2
    C,F,A,H--136228609(+) GTGCAG/AAACTG 1 -- ut31 ese312Minor allele frequency- A:0.01EA NA MN NS 1132
    rs413067241,2
    C,F--136228665(+) CCAATC/TAGCCA 1 -- ut312Minor allele frequency- T:0.02WA NA 238
    rs111011,2
    F--136228732(+) TCATAC/TGGCAC 1 -- ut31 ese31Minor allele frequency- T:0.00MN 184
    rs1920537651,2
    --136228749(+) GGAGCA/GAGGTG 1 -- ut310--------
    rs22401721,2
    C,F,H--136228795(+) TGAGAC/TAAGCC 1 -- ut3110Minor allele frequency- T:0.20EA NA NS 2152
    rs1468675341,2
    C--136228836(+) GGAGA-/AGAGAGA 1 -- ut310--------
    rs413099561,2
    C--136228862(+) AGCCAC/TTGCTC 1 -- ut310--------
    rs10597731,2
    C,F,A,H--136228865(-) ATCGAC/G/TCAATG 2 -- ut3130EA MN NA NS WA CSA 4513
    rs1494253011,2
    --136228867(+) TTGCTC/TGATCT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SURF4 (136228325 - 136242970 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for SURF4:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2739138CNV Deletion23290073
    nsv894081CNV Loss21882294
    nsv894076CNV Loss21882294
    dgv8325n71CNV Loss21882294
    nsv894080CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 185660    OMIM disorders: --

    2 diseases for SURF4:    About MalaCards
    paraplegia    


    SURF4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SURF4
    Human Genome Epidemiology (HuGE) Navigator: SURF4 (4 documents)

    Export disorders for SURF4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SURF4 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with SURF4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The surf-4 gene encodes a novel 30 kDa integral membrane protein. (PubMed id 7540914)1, 2, 3 Reeves J.E. and Fried M. (1995)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    4. The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi. (PubMed id 18287528)1, 2 Mitrovic S.... Hauri H.-P. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46. (PubMed id 15308636)1, 2 Breuza L....Hauri H.P. (2004)
    7. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
    8. The human Surfeit locus. (PubMed id 9740673)1, 2 Duhig T.... Fried M. (1998)
    9. The organization and conservation of the human Surfeit gene cluster and its localization telomeric to the c-abl and can proto-oncogenes at chromosome band 9q34.1. (PubMed id 8499913)1, 3 Yon J....Fried M. (1993)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6836 HGNC: 11476 AceView: SURF1andSURF4 Ensembl:ENSG00000148248 euGenes: HUgn6836
    ECgene: SURF4 H-InvDB: SURF4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SURF4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SURF4 gene:
    Search GeneIP for patents involving SURF4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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