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Aliases for SURF2 Gene

Aliases for SURF2 Gene

  • Surfeit 2 2 3
  • Surfeit Locus Protein 2 2 3
  • SURF-2 3 4

External Ids for SURF2 Gene

Previous GeneCards Identifiers for SURF2 Gene

  • GC09P127313
  • GC09P127780
  • GC09P129577
  • GC09P131499
  • GC09P133252
  • GC09P135213
  • GC09P136223
  • GC09P105723

Summaries for SURF2 Gene

Entrez Gene Summary for SURF2 Gene

  • This gene shares a bidirectional promoter with surfeit 1 (SURF1; GeneID: 6834), which is located on the opposite strand. It encodes a conserved protein that is expressed in a variety of tissues. [provided by RefSeq, Jul 2013]

GeneCards Summary for SURF2 Gene

SURF2 (Surfeit 2) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SURF2 Gene

Genomics for SURF2 Gene

Regulatory Elements for SURF2 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SURF2 Gene

133,356,545 bp from pter
133,361,169 bp from pter
4,625 bases
Plus strand

Genomic View for SURF2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SURF2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SURF2 Gene

Proteins for SURF2 Gene

  • Protein details for SURF2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Surfeit locus protein 2
    Protein Accession:
    Secondary Accessions:
    • Q6IBP9
    • Q96CD1

    Protein attributes for SURF2 Gene

    256 amino acids
    Molecular mass:
    29648 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SURF2 Gene

Proteomics data for SURF2 Gene at MOPED

Post-translational modifications for SURF2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SURF2 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for SURF2 Gene

Domains for SURF2 Gene

Protein Domains for SURF2 Gene


Suggested Antigen Peptide Sequences for SURF2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SURF2 family.
  • Belongs to the SURF2 family.
genes like me logo Genes that share domains with SURF2: view

No data available for Gene Families for SURF2 Gene

Function for SURF2 Gene

Molecular function for SURF2 Gene

GENATLAS Biochemistry:
surfeit 2 (see SURF@)

Gene Ontology (GO) - Molecular Function for SURF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with SURF2: view

Animal Model Products

miRNA for SURF2 Gene

miRTarBase miRNAs that target SURF2

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SURF2

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for SURF2 Gene

Localization for SURF2 Gene

Subcellular locations from

Jensen Localization Image for SURF2 Gene COMPARTMENTS Subcellular localization image for SURF2 gene
Compartment Confidence
nucleus 3
extracellular 2
cytosol 1

Gene Ontology (GO) - Cellular Components for SURF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
GO:0005886 plasma membrane IDA --
genes like me logo Genes that share ontologies with SURF2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SURF2 Gene

Pathways for SURF2 Gene

SuperPathways for SURF2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SURF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with SURF2: view

No data available for Pathways by source for SURF2 Gene

Transcripts for SURF2 Gene

mRNA/cDNA for SURF2 Gene

Unigene Clusters for SURF2 Gene

Surfeit 2:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SURF2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SURF2 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7
SP1: - - - -
SP2: - - -
SP3: - - - - - -
SP4: - - - - - - - -
SP5: - -
SP6: -

Relevant External Links for SURF2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SURF2 Gene

mRNA expression in normal human tissues for SURF2 Gene

mRNA differential expression in normal tissues according to GTEx for SURF2 Gene

This gene is overexpressed in Testis (4.8).

Protein differential expression in normal tissues for SURF2 Gene

This gene is overexpressed in Lung (62.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SURF2 Gene

SOURCE GeneReport for Unigene cluster for SURF2 Gene Hs.159448

genes like me logo Genes that share expressions with SURF2: view

Expression partners for SURF2 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SURF2 Gene

Orthologs for SURF2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SURF2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SURF2 35
  • 80.08 (n)
  • 77.34 (a)
SURF2 36
  • 78 (a)
(Canis familiaris)
Mammalia SURF2 35
  • 79.58 (n)
  • 76.68 (a)
SURF2 36
  • 74 (a)
(Mus musculus)
Mammalia Surf2 35
  • 73.59 (n)
  • 69.8 (a)
Surf2 16
Surf2 36
  • 69 (a)
(Pan troglodytes)
Mammalia SURF2 35
  • 92.43 (n)
  • 91.63 (a)
SURF2 36
  • 95 (a)
(Monodelphis domestica)
Mammalia SURF2 36
  • 60 (a)
(Gallus gallus)
Aves SURF2 35
  • 65.98 (n)
  • 62.55 (a)
SURF2 36
  • 55 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.10001 35
surf2 35
  • 60.29 (n)
  • 57.83 (a)
African clawed frog
(Xenopus laevis)
Amphibia surf2-prov 35
(Danio rerio)
Actinopterygii zgc:101084 35
  • 55.36 (n)
  • 46.26 (a)
SURF2 36
  • 42 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9263 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2405 36
  • 33 (a)
Species with no ortholog for SURF2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SURF2 Gene

Gene Tree for SURF2 (if available)
Gene Tree for SURF2 (if available)

Paralogs for SURF2 Gene

No data available for Paralogs for SURF2 Gene

Variants for SURF2 Gene

Sequence variations from dbSNP and Humsavar for SURF2 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs12763 - 133,360,384(+) ATGAG(A/G)GCAGG missense, reference
rs1057411 -- 133,360,375(+) AGGCC(A/C)CTGAT reference, missense
rs1179032 -- 133,360,709(+) TGTGG(C/T)GTGTT intron-variant
rs1620024 -- 133,359,917(+) GTGTG(A/G)AAGTA intron-variant
rs1620025 -- 133,359,919(+) GTGAA(A/G)GTACC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SURF2 Gene

Variant ID Type Subtype PubMed ID
esv2739138 CNV Deletion 23290073
nsv894057 CNV Gain 21882294
dgv8325n71 CNV Loss 21882294
nsv894076 CNV Loss 21882294
nsv894079 CNV Loss 21882294
nsv894080 CNV Loss 21882294
nsv894081 CNV Loss 21882294

Relevant External Links for SURF2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SURF2 Gene

Disorders for SURF2 Gene

Relevant External Links for SURF2

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for SURF2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for SURF2 Gene

Publications for SURF2 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48
  3. The Surf-1 and Surf-2 genes and their essential bidirectional promoter elements are conserved between mouse and human. (PMID: 7702754) Lennard A. … Fried M. (DNA Cell Biol. 1994) 3 4
  4. The organization and conservation of the human Surfeit gene cluster and its localization telomeric to the c-abl and can proto-oncogenes at chromosome band 9q34.1. (PMID: 8499913) Yon J. … Fried M. (Hum. Mol. Genet. 1993) 3
  5. The human Surfeit locus. (PMID: 9740673) Duhig T. … Fried M. (Genomics 1998) 3

Products for SURF2 Gene

Sources for SURF2 Gene

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