Aliases for SUPV3L1 Gene
External Ids for SUPV3L1 Gene
Previous GeneCards Identifiers for SUPV3L1 Gene
GeneCards Summary for SUPV3L1 Gene
SUPV3L1 (Suppressor Of Var1, 3-Like 1 (S. Cerevisiae)) is a Protein Coding gene. GO annotations related to this gene include RNA binding and helicase activity.
UniProtKB/Swiss-Prot for SUPV3L1 Gene
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3 overhang double-stranded RNA with a 3-to-5 directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5-to-3 direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.