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SUPT7L Gene

protein-coding   GIFtS: 50
GCID: GC02M027873

Suppressor Of Ty 7 (S. Cerevisiae)-Like

  See SUPT7L-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Suppressor Of Ty 7 (S. Cerevisiae)-Like1 2     KIAA07643 5
Adenocarcinoma Antigen ART12 3     SPT7L2
Suppressor Of Ty 7-Like2 3     STAF652
STAF65gamma2 3     STAF65(gamma)2
SPTF-Associated Factor 65 Gamma2 3     STAGA Complex 65 Gamma Subunit2
STAF65G2 5     STAGA Complex 65 Subunit Gamma2
SUPT7H2 5     SPT7l5

External Ids:    HGNC: 306321   Entrez Gene: 99132   Ensembl: ENSG000001197607   OMIM: 6127625   UniProtKB: O948643   

Export aliases for SUPT7L gene to outside databases

Previous GC identifers: GC02M027786 GC02M027727 GC02M027614


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SUPT7L Gene:
SUPT7L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301)
acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 (PubMed
11564863)).(supplied by OMIM, Apr 2009)

GeneCards Summary for SUPT7L Gene:
SUPT7L (suppressor of Ty 7 (S. cerevisiae)-like) is a protein-coding gene. Diseases associated with SUPT7L include adenocarcinoma. GO annotations related to this gene include transcription coactivator activity and histone acetyltransferase activity.

Gene Wiki entry for SUPT7L Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_022184.16  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SUPT7L gene promoter:
         TBP   IRF-2   Elk-1   p300   TFIID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSUPT7L promoter sequence
   Search Chromatin IP Primers for SUPT7L

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SUPT7L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p23.3   Ensembl cytogenetic band:  2p23.3   HGNC cytogenetic band: 2p23.3

SUPT7L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SUPT7L gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M027873:  view genomic region     (about GC identifiers)

Start:
27,873,679 bp from pter      End:
27,886,676 bp from pter
Size:
12,998 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ST65G_HUMAN, O94864 (See protein sequence)
Recommended Name: STAGA complex 65 subunit gamma  
Size: 414 amino acids; 46193 Da
Subunit: Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, SUPT7L,
GCN5L2, TAF5L, TAF6L, TADA3L, TAD1L, TAF10, TAF12 and TAF9
Sequence caution: Sequence=BAA34484.2; Type=Erroneous initiation;
Secondary accessions: Q6IB21 Q9H2T6
Alternative splicing: 2 isoforms:  O94864-1   O94864-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SUPT7L: NX_O94864

Explore proteomics data for SUPT7L at MOPED

Post-translational modifications: 

  • Sumoylated1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SUPT7L Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001269658.1  NP_001269659.1  NP_001269660.1  NP_001269661.1  NP_055675.1  

    ENSEMBL proteins: 
     ENSP00000336750   ENSP00000385436   ENSP00000384469   ENSP00000441110   ENSP00000385218  
    Reactome Protein details: O94864

    SUPT7L Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for SUPT7L

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR006565 BTP

    Graphical View of Domain Structure for InterPro Entry O94864

    ProtoNet protein and cluster: O94864


    Find genes that share domains with SUPT7L           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003713transcription coactivator activity IDA11564863
    GO:0004402contributes to histone acetyltransferase activity IDA11564863
    GO:0005515protein binding IPI15870280
         
    Find genes that share ontologies with SUPT7L           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Supt7l):
     mortality/aging 

    Find genes that share phenotypes with SUPT7L           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SUPT7L
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SUPT7L
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SUPT7L

    miRNA
    Products:
        
    miRTarBase miRNAs that target SUPT7L:
    hsa-mir-23b-3p (MIRT046328), hsa-mir-18a-5p (MIRT031345), hsa-mir-128-3p (MIRT021909)

    Block miRNA regulation of human, mouse, rat SUPT7L using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SUPT7L (see all 26):
    hsa-miR-3164 hsa-miR-3149 hsa-miR-320a hsa-miR-548j hsa-miR-548i hsa-miR-138-2* hsa-miR-890 hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidSUPT7L 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SUPT7L

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    GenScript: all cDNA clones in your preferred vector: SUPT7L (NM_014860)
    Sino Biological Human cDNA Clone for SUPT7L
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUPT7L

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUPT7L


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ST65G_HUMAN, O94864: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    cytoskeleton1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus NAS10987294
    GO:0030914STAGA complex IDA11564863

    Find genes that share ontologies with SUPT7L           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SUPT7L About    
    See pathways by source

    SuperPathContained pathways About
    1RNA Polymerase I Promoter Opening
    HATs acetylate histones0.34
    Chromatin organization0.34
    Chromatin modifying enzymes0.34
    2Validated targets of C-MYC transcriptional activation
    Validated targets of C-MYC transcriptional activation
    3C-MYC pathway
    C-MYC pathway


    Find genes that share SuperPaths with SUPT7L           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for SUPT7L
        C-MYC pathway
    Validated targets of C-MYC transcriptional activation


    1 Reactome Pathway for SUPT7L
        HATs acetylate histones


        Pathway & Disease-focused RT2 Profiler PCR Arrays including SUPT7L: 
              Epigenetic Chromatin Modification Enzymes in human mouse rat
              Prostate Cancer in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for SUPT7L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SUPT7L (O948642, 3 ENSP000003367504) via UniProtKB, MINT, STRING, and/or I2D (see all 43)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PTNP212462, 3MINT-63241 I2D: score=5 
    TAF9Q165943, ENSP000002178934I2D: score=1 STRING: ENSP00000370201 STRING: ENSP00000217893
    KAT2AQ928303, ENSP000002259164I2D: score=2 STRING: ENSP00000225916
    CDCA4Q9BXL83, ENSP000003372264I2D: score=1 STRING: ENSP00000337226
    MED1Q156483, ENSP000003006514I2D: score=1 STRING: ENSP00000300651
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006325chromatin organization TAS--
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0043966histone H3 acetylation IDA11564863
    GO:0051457maintenance of protein location in nucleus IDA15870280

    Find genes that share ontologies with SUPT7L           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SUPT7L (ST65G)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SUPT7L gene (5 alternative transcripts): 
    NM_001282729.1  NM_001282730.1  NM_001282731.1  NM_001282732.1  NM_014860.2  

    Unigene Cluster for SUPT7L:

    Suppressor of Ty 7 (S. cerevisiae)-like
    Hs.6232  [show with all ESTs]
    Unigene Representative Sequence: AB018307
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000337768(uc002rlh.1 uc002rli.1 uc010ymf.1 uc010ezh.1 uc002rlj.1)
    ENST00000406540 ENST00000405491 ENST00000464789 ENST00000404798
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SUPT7L (see all 26):
    hsa-miR-3164 hsa-miR-3149 hsa-miR-320a hsa-miR-548j hsa-miR-548i hsa-miR-138-2* hsa-miR-890 hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidSUPT7L 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Predesigned siRNA for gene silencing in human, mouse, rat SUPT7L
    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUPT7L
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SUPT7L
      QuantiTect SYBR Green Assays in human, mouse, rat SUPT7L
      QuantiFast Probe-based Assays in human, mouse, rat SUPT7L

    Additional mRNA sequence: 

    AB018307.1 AF197954.1 AF224759.1 AK000329.1 AK000616.1 AK304889.1 BC045638.1 BC074000.1 
    CR456983.1 

    23 DOTS entries:

    DT.100802471  DT.100826887  DT.100703335  DT.100675496  DT.95149029  DT.121010706  DT.448385  DT.100705742 
    DT.100802465  DT.121010754  DT.121010765  DT.100826886  DT.121010692  DT.100675893  DT.411112  DT.95114895 
    DT.121010716  DT.100802467  DT.100802468  DT.121010697  DT.40106916  DT.99981108  DT.95114894 

    Selected AceView cDNA sequences (see all 368):

    AW513082 BQ000397 BM817448 BM661976 AW612224 AI339320 BX363918 AF197954 
    AA130334 AA683150 BX338203 AI678839 CA428867 AA678716 AA825187 NM_014860 
    AA082254 AA929051 AA742838 BQ007534 BX343124 AA625952 AK000329 BE504593 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SUPT7L (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b · 3c · 3d · 3e · 3f · 3g ^ 4a · 4b ^ 5 ^ 6
    SP1:                          -     -     -     -     -                                                   
    SP2:                          -     -                                                                     
    SP3:                          -     -     -     -     -                                                   
    SP4:                          -     -     -     -                                                         
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for SUPT7L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SUPT7L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTATACAGCC
    SUPT7L Expression
    About this image

    SUPT7L Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SUPT7L Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.6232

    UniProtKB/Swiss-Prot: ST65G_HUMAN, O94864
    Tissue specificity: Expressed at high levels in adenocarcinomas and gliomas and low in esophageal cancers and
    malignant hematological disease. Also expressed at high level in the thymus, low in peripheral blood mononuclear
    cells, and lowest in the stomach, small intestine, and skeletal muscle

        Pathway & Disease-focused RT2 Profiler PCR Arrays including SUPT7L: 
              Epigenetic Chromatin Modification Enzymes in human mouse rat
              Prostate Cancer in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for SUPT7L
    OriGene qSTAR qPCR primer pairs in human, mouse for SUPT7L
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SUPT7L
    QuantiTect SYBR Green Assays in human, mouse, rat SUPT7L
    QuantiFast Probe-based Assays in human, mouse, rat SUPT7L
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUPT7L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SUPT7L gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Supt7l1 , 5 suppressor of Ty 7 (S. cerevisiae)-like5
    suppressor of Ty 7-like1
    90.86(n)1
    95.87(a)1
      5 (17.27 cM)5
    721951  NM_028150.21  NP_082426.11 
     315145695 
    chicken
    (Gallus gallus)
    Aves SUPT7L1 suppressor of Ty 7 (S. cerevisiae)-like 78.88(n)
    87.14(a)
      421421  XM_419474.3  XP_419474.2 
    lizard
    (Anolis carolinensis)
    Reptilia SUPT7L6
    suppressor of Ty 7 (S. cerevisiae)-like
    85(a)
    1 ↔ 1
    2(125195445-125214238)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.61492 Xenopus laevis transcribed sequence with moderate similarity more 75.2(n)    BJ618022.1 
    zebrafish
    (Danio rerio)
    Actinopterygii supt7l1 suppressor of Ty 7 (S. cerevisiae)-like 67.65(n)
    72.73(a)
      503605  NM_001013292.2  NP_001013310.1 


    ENSEMBL Gene Tree for SUPT7L (if available)
    TreeFam Gene Tree for SUPT7L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SUPT7L (see all 317)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1472380881,2
    --27795950(+) AGAAGA/CCCCTT 1 -- ds50010--------
    rs1397713851,2
    C--27796028(+) TGAGCC/TGATAC 1 -- ds50010--------
    rs87311,2
    C,F,O,A,H--27796035(+) ATACTC/GTTCCA 1 -- ds500125Minor allele frequency- G:0.41MN EA NA NS WA CSA 3164
    rs73821,2
    C,F,A,H--27796124(+) CTGGTG/AACCAC 1 -- ds500123Minor allele frequency- A:0.36MN NA NS EA WA 2854
    rs153381,2
    H--27796225(+) CAGCCA/TAGGAA 1 -- ds50015Minor allele frequency- T:0.01MN NS EA 604
    rs1900279271,2
    --27796283(+) ATCAAA/CCAACG 1 -- ds50010--------
    rs1499471051,2
    C--27796326(+) CATTAC/TAGGAC 1 -- ds50010--------
    rs1441345911,2
    C--27796340(+) AGGTTG/TGTTGA 1 -- ds50010--------
    rs1811045611,2
    C--27796414(+) CTTTTA/TAATTT 1 -- ut310--------
    rs133989271,2
    C,F,A,H--27796517(+) GGCCAG/CATGTC 1 -- ut3119Minor allele frequency- C:0.09NS EA NA CSA WA 2278

    HapMap Linkage Disequilibrium report for SUPT7L (27873679 - 27886676 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for SUPT7L: --
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing SUPT7L
    DNA2.0 Custom Variant and Variant Library Synthesis for SUPT7L

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612762    OMIM disorders: --

    1 disease for SUPT7L:    
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    adenocarcinoma


    Find genes that share disorders with SUPT7L           About GenesLikeMe


    Export disorders for SUPT7L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SUPT7L gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with SUPT7L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo. (PubMed id 11564863)1, 2, 3 Martinez E.... Roeder R.G. (Mol. Cell. Biol. 2001)
    2. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1998)
    3. Identification of a small TAF complex and its role in the assembly of TAF-containing complexes. (PubMed id 17375202)1, 2 Demeny M.A.... Tora L. (PLoS ONE 2007)
    4. Systematic identification and analysis of mammalian small ubiquitin- like modifier substrates. (PubMed id 15561718)1, 2 Gocke C.B.... Kang J. (J. Biol. Chem. 2005)
    5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. A new tumor-rejection antigen recognized by cytotoxic T lymphocytes infiltrating into a lung adenocarcinoma. (PubMed id 10987294)1, 2 Nishizaka S.... Shichijo S. (Cancer Res. 2000)
    8. A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex. (PubMed id 23382074)1 Armour S.M....Sinclair D.A. (Mol. Cell. Biol. 2013)
    9. GCN5 acetylates and regulates the stability of the oncoprotein E2A-PBX1 in acute lymphoblastic leukemia. (PubMed id 23044487)1 Holmlund T....Wallberg A.E. (Leukemia 2013)
    10. Comparative proteomic analysis identifies a role for SUMO in protein quality control. (PubMed id 21693764)1 Tatham M.H....Hay R.T. (Sci Signal 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9913 HGNC: 30632 AceView: STAF65(gamma) Ensembl:ENSG00000119760 euGenes: HUgn9913
    ECgene: SUPT7L H-InvDB: SUPT7L

    (According to HUGE)
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    HUGE: KIAA0764

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SUPT7L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for SUPT7L gene:
    Search GeneIP for patents involving SUPT7L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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