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SUPT20H Gene

protein-coding   GIFtS: 48
GCID: GC13M037584

Suppressor Of Ty 20 Homolog (S. Cerevisiae)

(Previous names: chromosome 13 open reading frame 19, family with sequence...)
(Previous symbols: C13orf19, FAM48A)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Suppressor Of Ty 20 Homolog (S. Cerevisiae)1 2     C132
C13orf191 2 3 5     SPT202
FAM48A1 2 3 5     Protein FAM48A2
Family With Sequence Similarity 48, Member A1 2     Transcription Factor SPT20 Homolog2
Transcription Factor (P38 Interacting Protein)1 2     Tumor Rejection Antigen2
P38IP2 5     P38-Interacting Protein3
Chromosome 13 Open Reading Frame 191     p38IP3
P38 Interacting Protein1     

External Ids:    HGNC: 205961   Entrez Gene: 555782   Ensembl: ENSG000001027107   OMIM: 6134175   UniProtKB: Q8NEM73   

Export aliases for SUPT20H gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SUPT20H Gene:
SUPT20H (suppressor of Ty 20 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with SUPT20H include ataxia, and retinitis. GO annotations related to this gene include transcription cofactor activity.

UniProtKB/Swiss-Prot: SP20H_HUMAN, Q8NEM7
Function: Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation.
Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream
from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail
(By similarity). Required for starvation-induced ATG9A trafficking during autophagy

Gene Wiki entry for SUPT20H (FAM48A) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000013.11  NT_024524.15  NC_018924.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for SUPT20H
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSUPT20H promoter sequence
   Search Chromatin IP Primers for SUPT20H

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SUPT20H


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q13.3   Ensembl cytogenetic band:  13q13.3   HGNC cytogenetic band: 13q13

SUPT20H Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SUPT20H gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M037584:  view genomic region     (about GC identifiers)

Start:
37,583,449 bp from pter      End:
37,633,850 bp from pter
Size:
50,402 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SP20H_HUMAN, Q8NEM7 (See protein sequence)
Recommended Name: Transcription factor SPT20 homolog  
Size: 779 amino acids; 85789 Da
Subunit: Interacts with MAPK14. Interacts with ATG9A
Sequence caution: Sequence=AAQ15220.1; Type=Frameshift; Positions=562; Sequence=AAQ15220.1; Type=Miscellaneous
discrepancy; Note=Intron retention;
Secondary accessions: Q71RF3 Q9Y6A6
Alternative splicing: 2 isoforms:  Q8NEM7-1   Q8NEM7-2   

Explore the universe of human proteins at neXtProt for SUPT20H: NX_Q8NEM7

Explore proteomics data for SUPT20H at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys155, Lys269, Lys351, Lys418
  • Modification sites at PhosphoSitePlus

  • See SUPT20H Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001014308.2  NP_001265409.1  NP_001265410.1  NP_001265411.1  NP_060039.1  

    ENSEMBL proteins: 
     ENSP00000473592   ENSP00000473416   ENSP00000353388   ENSP00000417510   ENSP00000419787  
     ENSP00000348512   ENSP00000218894   ENSP00000419754   ENSP00000420170   ENSP00000439000  
    Reactome Protein details: Q8NEM7

    SUPT20H Human Recombinant Protein Products:

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    Novus Biologicals SUPT20H Lysate
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

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    SUPT20H Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR021950 Spt20

    Graphical View of Domain Structure for InterPro Entry Q8NEM7

    ProtoNet protein and cluster: Q8NEM7

    UniProtKB/Swiss-Prot: SP20H_HUMAN, Q8NEM7
    Similarity: Belongs to the SPT20 family


    SUPT20H for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SP20H_HUMAN, Q8NEM7
    Function: Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation.
    Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream
    from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail
    (By similarity). Required for starvation-induced ATG9A trafficking during autophagy

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003712transcription cofactor activity IEA--
    GO:0005515protein binding IPI16751104
         
    SUPT20H for ontologies           About GeneDecksing


    Phenotypes:
         8 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Supt20):
     cardiovascular system  cellular  embryogenesis  growth/size/body  mortality/aging 
     nervous system  pigmentation  vision/eye 

    SUPT20H for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SUPT20H
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SUPT20H

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SUPT20H
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SUPT20H

    miRNA
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    miRTarBase miRNAs that target SUPT20H:
    hsa-mir-615-3p (MIRT039729), hsa-let-7b-5p (MIRT052010)

    Block miRNA regulation of human, mouse, rat SUPT20H using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate SUPT20H
    SwitchGear 3'UTR luciferase reporter plasmidSUPT20H 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SUPT20H

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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUPT20H

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUPT20H


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SP20H_HUMAN, Q8NEM7: Nucleus

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000124SAGA complex IEA--
    GO:0070461SAGA-type complex IDA18838386

    SUPT20H for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SUPT20H About    
    See pathways by source

    SuperPathContained pathways About
    1RNA Polymerase I Promoter Opening
    HATs acetylate histones0.34
    Chromatin organization0.34
    Chromatin modifying enzymes0.34

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for SUPT20H
        HATs acetylate histones



    SUPT20H for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SUPT20H
    Interactions:

        Search GeneGlobe Interaction Network for SUPT20H

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SUPT20H (Q8NEM71, 2, 3 ENSP000002188944) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATG9AQ7Z3C61, 2, ENSP000003551734EBI-7568679,EBI-727146 MINT-7557407 MINT-7557250 MINT-7557367 MINT-7557337 MINT-7557381 MINT-7557272 MINT-7557312 MINT-7557352 STRING: ENSP00000355173
    ATXN1P542532, 3, ENSP000002447694MINT-2874351 I2D: score=3 STRING: ENSP00000244769
    MAPK14Q165391, 2, 3, ENSP000002297944EBI-946984,EBI-73946 MINT-7557407 I2D: score=5 STRING: ENSP00000229794
    UBQLN4Q9NRR52, 3, ENSP000003572924MINT-2874332 I2D: score=3 STRING: ENSP00000357292
    KAT2AQ928303, ENSP000002259164I2D: score=1 STRING: ENSP00000225916
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006325chromatin organization TAS--
    GO:0006914autophagy IEA--
    GO:0007369gastrulation IEA--

    SUPT20H for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SUPT20H (SP20H)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SUPT20H gene (5 alternative transcripts): 
    NM_001014286.2  NM_001278480.1  NM_001278481.1  NM_001278482.1  NM_017569.3  

    Unigene Cluster for SUPT20H:

    Suppressor of Ty 20 homolog (S. cerevisiae)
    Hs.435815  [show with all ESTs]
    Unigene Representative Sequence: AJ130894
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24):
    ENST00000484078(uc001uwe.3) ENST00000490716(uc001uwd.3 uc001uwf.3 uc010abt.3 uc001uwk.3)
    ENST00000495071 ENST00000360252(uc001uwg.3 uc001uwh.3 uc001uwi.3 uc001uwj.3)
    ENST00000475892 ENST00000472948 ENST00000469488 ENST00000356185 ENST00000350612
    ENST00000473871 ENST00000464744 ENST00000466563 ENST00000493537(uc001uwl.1)
    ENST00000476539 ENST00000490602 ENST00000478911 ENST00000464572 ENST00000483241

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidSUPT20H 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SUPT20H
    Clone
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat SUPT20H
      QuantiFast Probe-based Assays in human, mouse, rat SUPT20H

    Additional mRNA sequence: 

    AF093250.1 AF445026.1 AJ130894.1 AK021457.1 AK026091.1 AK027554.1 AK056121.1 AK225376.1 
    AK292376.1 AK304227.1 BC001145.1 BC030686.2 Y13897.1 

    Selected DOTS entries (see all 36):

    DT.100828881  DT.86998283  DT.95200281  DT.100801738  DT.95131357  DT.75163990  DT.100828891  DT.97862754 
    DT.100828884  DT.100039725  DT.100828865  DT.91852302  DT.91985875  DT.87079126  DT.120794504  DT.97770871 
    DT.120794396  DT.92454826  DT.319420  DT.100780681  DT.120794477  DT.120794516  DT.91786662  DT.92454813 

    Selected AceView cDNA sequences (see all 239):

    BM460220 BP351477 BM853217 CB134412 BQ720121 AK027554 BM982033 BM724554 
    AL526315 AJ312119 AI983720 AI784313 BQ642028 CR625667 AL043075 R16194 
    AL044978 BQ058622 Z40072 BI792464 BM504674 AI656349 AI590991 AK056121 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SUPT20H (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17
    SP1:              -                                   -                                                                                       
    SP2:              -                                   -                                                                                       
    SP3:                                                                                                                                          
    SP4:                                                                                                                                          
    SP5:                                                                          -                                                               


    ECgene alternative splicing isoforms for SUPT20H

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SUPT20H expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SUPT20H Expression
    About this image


    SUPT20H expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Gonad
             Primary Oocyte Primary Follicle
     
     Testis (Reproductive System)
             XY Germ Cells Testis Cord
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Ovary (Reproductive System)
             Primary Oocyte Primary Follicle
     
     Eye (Sensory Organs)
             Retina
    SUPT20H Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SUPT20H Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.435815

    UniProtKB/Swiss-Prot: SP20H_HUMAN, Q8NEM7
    Tissue specificity: Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several
    fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate
    tissues

        Custom PCR Arrays for SUPT20H
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUPT20H

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SUPT20H gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Supt205 family with sequence similarity 48, member A   --   3 (25.59 cM) 54693105 
    chicken
    (Gallus gallus)
    Aves FAM48A1 family with sequence similarity 48, member A 81.53(n)
    84.5(a)
      418896  NM_001006275.1  NP_001006275.1 
    lizard
    (Anolis carolinensis)
    Reptilia SUPT20H6
    suppressor of Ty 20 homolog (S. cerevisiae)
    76(a)
    1 ↔ 1
    2(82488529-82532883)
    African clawed frog
    (Xenopus laevis)
    Amphibia BI349358.12   -- 75.43(n)    BI349358.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.199252 Transcribed sequence with weak similarity to protein more 74.36(n)    BU710497.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Spt206
    --
    9(a)
    1 ↔ 1
    3L(13495807-13504386)


    ENSEMBL Gene Tree for SUPT20H (if available)
    TreeFam Gene Tree for SUPT20H (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SUPT20H gene
    3 SIMAP similar genes for SUPT20H using alignment to 6 protein entries:     SP20H_HUMAN (see all proteins):
    FAM48A    SUPT20HL2    SUPT20HL1

    SUPT20H for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for SUPT20H
    PGOHUM00000241211 PGOHUM00000241666


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SUPT20H (see all 944)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1413767951,2
    C--18527778(+) TGTAGA/CTGAAA 2 -- int10--------
    rs1903776941,2
    --18527897(+) GGTATA/GTGTCA 2 -- int10--------
    rs2005345841,2
    C--18528056(+) ATAACT/CGAGAT 2 -- int11Minor allele frequency- C:0.00EU 593
    rs1999560731,2
    --18528064(+) GATTAA/CAAGTA 2 -- int10--------
    rs1477303961,2
    C--18528161(+) AAGTTA/TAAAAA 2 -- int11Minor allele frequency- T:0.00NA 4508
    rs360272201,2
    C,F--18528189(+) TAAGAG/CTATGA 2 -- int13Minor allele frequency- C:0.00NA EU 5825
    rs1173400341,2
    C,F--18528247(+) TGTATT/GTGTTA 2 -- ut311Minor allele frequency- G:0.03EA 120
    rs1855864581,2
    --18528420(+) CCCTGG/TTTTTA 2 -- ut310--------
    rs2019862331,2
    C--18528570(+) AGTAAT/CGCAAG 2 -- ut311Minor allele frequency- C:0.00EU 1323
    rs95941851,2
    C,F--18528581(+) ACTCAA/GAATTT 3 F syn1 ut313Minor allele frequency- G:0.01NA EU 5993

    HapMap Linkage Disequilibrium report for SUPT20H (37583449 - 37633850 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for SUPT20H: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SUPT20H
    DNA2.0 Custom Variant and Variant Library Synthesis for SUPT20H

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613417    OMIM disorders: --

    5 diseases for SUPT20H:    
    About MalaCards
    ataxia    retinitis    malaria    prostatitis
    breast cancer


    SUPT20H for disorders           About GeneDecksing


    Export disorders for SUPT20H gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SUPT20H gene, integrated from 10 sources (see all 25):
    (articles sorted by number of sources associating them with SUPT20H)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Functional analyses of C13orf19/P38IP in prostate cell lines. (PubMed id 16685401)1, 3, 9 Kunze D....Schmidt U. (Oncol. Rep. 2006)
    2. Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP. (PubMed id 19893488)1, 2 Webber J.L. and Tooze S.A. (EMBO J. 2010)
    3. p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation. (PubMed id 16751104)1, 2 Zohn I.E.... Niswander L. (Cell 2006)
    4. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (Nature 2004)
    5. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Identification of a novel gene on chromosome 13 between BRCA2 and Rb1. (PubMed id 11340631)1, 2 Schmidt U.... Wirth M.P. (Prostate 2001)
    8. Quantification of C13orf19/P38IP mRNA expression by quantitative real-time PCR in patients with urological malignancies. (PubMed id 15978328)1, 9 Schmidt U....Wirth M.P. (Cancer Lett. 2005)
    9. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PubMed id 24163370)1 Lu L....Zhang L. (J. Biol. Chem. 2013)
    10. The p38-interacting protein (p38IP) regulates G2/M progression by promoting I+-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5. (PubMed id 24220028)1 Liu X....Li Y. (J. Biol. Chem. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55578 HGNC: 20596 AceView: FAM48A Ensembl:ENSG00000102710 euGenes: HUgn55578
    ECgene: SUPT20H H-InvDB: SUPT20H

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SUPT20H Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for SUPT20H gene:
    Search GeneIP for patents involving SUPT20H

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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