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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SUN3 Gene

protein-coding   GIFtS: 48
GCID: GC07M048026

Sad1 And UNC84 Domain Containing 3

(Previous name: Sad1 and UNC84 domain containing 1)
(Previous symbol: SUNC1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Sad1 And UNC84 Domain Containing 31 2
SUNC11 2 3
Sad1 And UNC84 Domain Containing 11 2
Sad1/Unc-84 Domain-Containing Protein 12 3
Hypothetical Protein MGC333292
SUN Domain-Containing Protein 32

External Ids:    HGNC: 224291   Entrez Gene: 2569792   Ensembl: ENSG000001647447   UniProtKB: Q8TAQ93   

Export aliases for SUN3 gene to outside databases

Previous GC identifer: GC07M047912


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SUN3 Gene: 
SUN3 (Sad1 and UNC84 domain containing 3) is a protein-coding gene. Diseases associated with SUN3 include lateral sclerosis, and amyotrophic lateral sclerosis. An important paralog of this gene is SPAG4.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007819.17  NC_018918.2  NT_079592.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for SUN3
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSUN3 promoter sequence
   Search SABiosciences Chromatin IP Primers for SUN3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p12.3   Ensembl cytogenetic band:  7p12.3   HGNC cytogenetic band: 7p12.3

SUN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SUN3 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M048026:  view genomic region     (about GC identifiers)

Start:
48,026,745 bp from pter      End:
48,068,716 bp from pter
Size:
41,972 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 48,066,697-48,108,669     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SUN3_HUMAN, Q8TAQ9 (See protein sequence)
Recommended Name: SUN domain-containing protein 3  
Size: 357 amino acids; 40503 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Sequence caution: Sequence=AAP97300.1; Type=Frameshift; Positions=233, 242; Sequence=EAL23808.1; Type=Erroneous
gene model prediction;
Secondary accessions: A4D2F3 D3DVM3 Q4F965 Q7Z4U8
Alternative splicing: 2 isoforms:  Q8TAQ9-1   Q8TAQ9-2   

Explore the universe of human proteins at neXtProt for SUN3: NX_Q8TAQ9

Explore proteomics data for SUN3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8TAQ9

  • SUN3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SUN3 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001025190.1  NP_001271279.1  NP_689995.3  

    ENSEMBL proteins: 
     ENSP00000388627   ENSP00000297325   ENSP00000406887   ENSP00000378939   ENSP00000395392  
     ENSP00000409077   ENSP00000387525   ENSP00000410204  

    Human Recombinant Protein Products for SUN3: 
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    OriGene Purified Proteins for SUN3
    OriGene Protein Over-expression Lysate for SUN3
    OriGene MassSpec for SUN3 
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    Novus Biologicals SUN3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SUN3 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--
    GO:0034993SUN-KASH complex IEA--

    SUN3 for ontologies           About GeneDecksing



    SUN3 Antibody Products: 
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    Novus Biologicals SUN3 Antibodies
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    LSBio Antibodies in human, mouse, rat for SUN3 

    Assay Products for SUN3: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for SUN3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SUN3 
    Cloud-Clone Corp. CLIAs for SUN3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR012919 Sad1_UNC_C

    Graphical View of Domain Structure for InterPro Entry Q8TAQ9

    ProtoNet protein and cluster: Q8TAQ9

    1 Blocks protein domain: IPB012919 Sad1/UNC-like

    UniProtKB/Swiss-Prot: SUN3_HUMAN, Q8TAQ9
    Similarity: Contains 1 SUN domain


    SUN3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    SUN3 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SUN3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SUN3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SUN3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SUN3 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SUN3
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate SUN3
    SwitchGear 3'UTR luciferase reporter plasmidSUN3 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SUN3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SUN3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SUN3
    Sirion Biotech Customized adenovirus for overexpression of SUN3

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for SUN3 (see all 11)
    OriGene ORF clones in mouse, rat for SUN3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SUN3 (NM_022072)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SUN3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUN3
    Sirion Biotech Customized lentivirus for stable overexpression of SUN3 
                         Customized lentivirus expression plasmids for stable overexpression of SUN3 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for SUN3
    Search LifeMap BioReagents cell lines for SUN3
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUN3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SUN3

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for SUN3 (ENSP000002973254) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SUN1ENSP000003840154STRING: ENSP00000384015
    SUN2ENSP000002160644STRING: ENSP00000216064
    SYNE1ENSP000002653684STRING: ENSP00000265368
    SYNE2ENSP000003507194STRING: ENSP00000350719
    SYNE3ENSP000003343084STRING: ENSP00000334308
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SUN3

    Search CenterWatch for drugs/clinical trials and news about SUN3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SUN3 gene (3 alternative transcripts): 
    NM_001030019.1  NM_001284350.1  NM_152782.3  

    Unigene Cluster for SUN3:

    Sad1 and UNC84 domain containing 3
    Hs.406741  [show with all ESTs]
    Unigene Representative Sequence: AK302011
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000461953 ENST00000473723 ENST00000453071 ENST00000297325(uc003tog.3)
    ENST00000412371 ENST00000395572 ENST00000449896 ENST00000438771 ENST00000453192(uc011kcf.2)
    ENST00000412142(uc010kyq.3 uc003tof.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SUN3
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate SUN3
    SwitchGear 3'UTR luciferase reporter plasmidSUN3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SUN3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SUN3
    Clone
    Products:
         
    OriGene clones in human, mouse for SUN3 (see all 11)
    OriGene ORF clones in mouse, rat for SUN3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SUN3 (NM_022072)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SUN3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUN3
    Sirion Biotech Customized lentivirus for stable overexpression of SUN3 
                         Customized lentivirus expression plasmids for stable overexpression of SUN3 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SUN3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SUN3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUN3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUN3

    Additional mRNA sequence: 

    AF429967.1 AK302011.1 BC026189.2 DQ099386.1 

    4 DOTS entries:

    DT.92417580  DT.309219  DT.100743422  DT.99970208 

    24/28 AceView cDNA sequences (see all 28):

    BG184281 BX119032 AA813611 BP369275 BU623138 BI829140 BI825617 NM_152782 
    BC026189 AA883877 AA973064 AI017490 BI827929 BG772576 AI917508 BM554058 
    BI829985 AF429967 AI688144 BG720666 BP369413 AI208514 AW182987 AI222206 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SUN3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
    SP1:                    -                                             
    SP2:                                                                  
    SP3:                                                                  


    ECgene alternative splicing isoforms for SUN3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SUN3 expression in normal human tissues (normalized intensities)      SUN3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCAGAATAT
    SUN3 Expression
    About this image


    SUN3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Testis (Reproductive System)
             sperm   
     
     Trophoblast (Extraembryonic Tissues)
             Mural Trophectoderm Cells Mural Trophectoderm

    See SUN3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SUN3

    SOURCE GeneReport for Unigene cluster: Hs.406741
        SABiosciences Custom PCR Arrays for SUN3
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for SUN3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SUN3
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUN3
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUN3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUN3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SUN3 gene from 5/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sun31 , 5 Sad1 and UNC84 domain containing 31, 5 83.27(n)1
    82.35(a)1
      11 (5.77 cM)5
    1949741  NM_177576.31  NP_808244.11 
     90160545 
    chicken
    (Gallus gallus)
    Aves LOC7704051 SUN domain-containing protein 3-like 57.85(n)
    43.92(a)
      770405  XM_001233743.2  XP_001233744.2 
    zebrafish
    (Danio rerio)
    Actinopterygii SUN56
    Sad1 and UNC84 domain containing 5
    18(a)
    1 → many
    6(47982348-47999334)
    fruit fly
    (Drosophila melanogaster)
    Insecta spag46
    koi6
    klaroid
    20(a)
    15(a)
    possible ortholog
    1 ↔ many
    2L(11610510-11611772)
    2R(2702565-2705704)
    worm
    (Caenorhabditis elegans)
    Secernentea unc-846
    Nuclear migration and anchoring protein unc-84
    6(a)
    possible ortholog
    X(13584775-13589827)


    ENSEMBL Gene Tree for SUN3 (if available)
    TreeFam Gene Tree for SUN3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SUN3 gene
    SPAG42  SUN22  SUN12  SUN52  
    18/62 SIMAP similar genes for SUN3 using alignment to 5 protein entries:     SUN3_HUMAN (see all proteins) (see all similar genes):
    LGALS3    FAM3A    BUB1B    GNPTAB    NSRP1    THADA
    ZNF23    ARV1    ATL2    C12orf23    COX7A2    DAPK2
    LAMA5    LRTOMT    MKRN1    TMEM67    UTY    ZNF480

    SUN3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1002 SNPs in SUN3 are shown (see all 1002)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs107132641,2
    C,F--48026253(+) TGGGA-/TTTTTT 2 -- ds50013Minor allele frequency- T:0.33NA CSA 6
    rs1891737811,2
    --48026430(+) AAATAG/TACTCT 2 -- ds50010--------
    rs1393709651,2
    --48026472(+) GCAAAG/TGGTCA 2 -- ds50010--------
    rs1809093231,2
    --48026478(+) GGTCAC/TGGTCA 2 -- ds50010--------
    rs1849690651,2
    --48026579(+) ATAGTA/GGTGAT 2 -- ds50010--------
    rs1913091221,2
    --48026709(+) CAACAG/TGAAGC 2 -- ds50010--------
    rs1128404941,2
    C,F--48026725(+) TAAAGA/GCTAAA 2 -- ds50011Minor allele frequency- G:0.02NA 120
    rs1431751151,2
    C--48026742(+) CAAGGA/TTATTT 2 -- ds50010--------
    rs1475127861,2
    C--48026760(+) TTCCAC/TATTTT 2 -- ut310--------
    rs15544931,2
    C,A--48026823(+) GTTTTC/TTTCCC 2 -- ut31 trp35Minor allele frequency- T:0.00NA EA MN 438

    HapMap Linkage Disequilibrium report for SUN3 (48026745 - 48068716 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for SUN3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2665988CNV Deletion23128226
    nsv888004CNV Loss21882294
    nsv470221CNV Gain18288195
    nsv464442CNV Gain19166990

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SUN3
    DNA2.0 Custom Variant and Variant Library Synthesis for SUN3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for SUN3:    About MalaCards
    lateral sclerosis    amyotrophic lateral sclerosis


    SUN3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SUN3
    Human Genome Epidemiology (HuGE) Navigator: SUN3 (0 documents)

    Export disorders for SUN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SUN3 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with SUN3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    3. A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. (PubMed id 19193627)1 ChiA^ A....Traynor B.J. (2009)
    4. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    7. Cynomolgus monkey testicular cDNAs for discovery of novel human genes in the human genome sequence. (PubMed id 12498619)1 Osada N....Hashimoto K. (2002)
    8. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 256979 HGNC: 22429 AceView: SUNC1 Ensembl:ENSG00000164744 euGenes: HUgn256979
    ECgene: SUN3 H-InvDB: SUN3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SUN3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SUN3 gene:
    Search GeneIP for patents involving SUN3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
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     Browse Antibodies   Browse Cell Culture Products  
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     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
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     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SUN3  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for SUN3  
     OriGene MassSpec something-or-other for SUN3   OriGene clones in human, mouse for SUN3  
     OriGene qSTAR qPCR primer pairs in human, mouse for SUN3   OriGene Purified Protein for SUN3  
     OriGene ORF clones in mouse, rat for SUN3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SUN3   OriGene Custom Protein Services for SUN3  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SUN3
     QIAGEN SeqTarget long-range PCR primers for resequencing SUN3
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUN3
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SUN3
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUN3
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUN3
     GenScript Custom Purified and Recombinant Proteins Services for SUN3 GenScript cDNA clones with any tag delivered in your preferred vector for SUN3
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     Custom Peptide Services
     Search for Antibodies & Assays

     Search Regulatory tfbs for SUN3
     Search Chromatin IP Primers for SUN3
     RT2 qPCR Primer Assay in human, mouse, rat SUN3
     Search GNC Networks for SUN3
     SABiosciences Custom PCR Arrays for SUN3
     Search Tocris compounds for SUN3
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
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     Search Sino Biological for antibodies, proteins & pathways
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
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     See all of Abcam's Antibodies, Kits and Proteins for SUN3
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     Browse ProSpec Recombinant Proteins




     Proteins for SUN3
     Antibodies for SUN3
     ELISAs for SUN3
     CLIAs for SUN3
     Search LifeMap BioReagents cell lines for SUN3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUN3
     SwitchGear 3'UTR luciferase reporter plasmids for SUN3
     SwitchGear Promoter luciferase reporter plasmids for SUN3
     ThermoFisher Antibodies for SUN3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUN3
     inGenious Targeting Laboratory - Custom generated mouse model solutions for SUN3
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SUN3
    Customized:
     lentivirus for stable overexpression of SUN3
     lentivirus expression plasmids for stable overexpression of SUN3
     adenovirus for overexpression of SUN3
     LSBio Antibodies in human, mouse, rat for SUN3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
    transforming growth factor, beta 1
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    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


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