SUMO3 Gene
protein-coding GIFtS: 61
GCID: GC21M046191
|
|
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)(Previous names: SMT3 (suppressor of mif two 3, yeast) homolog 1, SMT3 suppressor...) (Previous symbol: SMT3H1)
| |
Aliases for SUMO3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| SMT3 Suppressor Of Mif Two 3 Homolog 3 (S. Cerevisiae)1 2 | | SMT3 Homolog 12 3 | | SMT3H11 2 3 5 | | SMT3 (Suppressor Of Mif Two 3, Yeast) Homolog 11 | | SMT3A1 2 | | SMT3 Suppressor Of Mif Two 3 Homolog 3 (Yeast)1 | | Ubiquitin-Like Protein SMT3B2 3 | | Small Ubiquitin-Related Modifier 32 | | SUMO-22 3 | | SMT3 Suppressor Of Mif Two 3 Homolog 12 | | SUMO-32 3 | | Ubiquitin-Like Protein SMT3A2 | | Smt3B2 3 | | SMT3B3 |
Export aliases for SUMO3 gene to outside databasesPrevious GC identifers: GC21M045083 GC21M045049 GC21M031598 |
Summaries for SUMO3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for SUMO3: SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins andaffect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation,sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation,apoptosis, and protein stability (Su and Li, 2002 (PubMed 12383504)).(supplied by OMIM, Mar 2008) UniProtKB/Swiss-Prot: SUMO3_HUMAN, P55854Function: Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as alysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist ofubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNAreplication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prioractivation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such asPIAS1-4, RANBP2 or CBX4 Gene Wiki entry for SUMO3
|
Genomic Views for SUMO3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000021.8 NC_018932.1 NT_011515.12
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SUMO3 gene promoter: p53 AML1a AP-1 ATF-2 MEF-2A c-Jun aMEF-2 ATF6 Other transcription factors
Search SABiosciences Chromatin IP Primers for SUMO3
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUMO3 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 21q22.3 Ensembl cytogenetic band: 21q22.3 HGNC cytogenetic band: 21q22.3SUMO3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 21 GeneLoc Exon Structure GeneLoc location for GC21M046191: view genomic region
(about GC identifiers)
Start:
|
46,191,374 bp from pter |
End:
|
46,238,694 bp from pter |
Size:
|
47,321 bases |
Orientation:
|
minus strand |
|
Proteins for SUMO3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SUMO3_HUMAN, P55854 (See
protein sequence)Recommended Name: Small ubiquitin-related modifier 3 precursor Size: 103 amino acids; 11637 Da
Subunit: Covalently attached to a number of proteins (By similarity). Interacts with USP25 (via ts SIM domain); theinteraction sumoylates USP25 and inhibits its ubiquitin hydrolyzing activity. Interacts with SAE2 and UBE2I
Subcellular location: Cytoplasm
Caution: Frequently wrongly assigned as SMT3A in many databases and publications. However, according to initialnomenclature, SUMO3 corresponds to SMT3B (PubMed:10692421)
2 PDB 3D structures from and Proteopedia for SUMO3:1U4A (3D)
  2IO1 (3D)
 
Secondary accessions: B2R5X4 Q53HI9 Q6FGD4 Q9BWR4Explore the universe of human proteins at neXtProt for SUMO3: NX_P55854
Post-translational modifications:
Polymeric chains can be formed through Lys-11 cross-linking1
Cleavage of precursor form by SENP1, SENP2 or SENP5 is necessary for function1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P55854 SUMO3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_008867.2 ENSEMBL proteins: ENSP00000395184 ENSP00000412358 ENSP00000380995 ENSP00000330343 ENSP00000380990 ENSP00000409666 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
SUMO3 for ontologies About GeneDecksing
SUMO3 Antibody Products: Assay Products for SUMO3: |
Protein
Domains / Families for SUMO3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SUMO3 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P55854ProtoNet protein and cluster: P55854 1 Blocks protein family: IPB000626 Ubiquitin domain
UniProtKB/Swiss-Prot: SUMO3_HUMAN, P55854Similarity: Belongs to the ubiquitin family. SUMO subfamilySimilarity: Contains 1 ubiquitin-like domain |
Function for SUMO3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: SUMO3_HUMAN, P55854Function: Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as alysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist ofubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNAreplication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prioractivation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such asPIAS1-4, RANBP2 or CBX4
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUMO3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUMO3 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SUMO3 (NM_006936) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SUMO3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUMO3  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUMO3 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
SUMO3 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SUMO3:
|
Pathways & Interactions for SUMO3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Protein Stability | | | 2 | RNA transport | | | 3 | Diurnally regulated genes with circadian orthologs | |
Pathway sources See GeneCards unified pathways Show all pathways
1
Cell Signaling Technology (CST) Pathway for SUMO3 1 BioSystems Pathway for SUMO3 
1
Kegg Pathway (Kegg details for SUMO3):
SUMO3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SUMO3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/238 Interacting proteins for SUMO3 (P558541, 2, 3 ENSP000003303434) via UniProtKB, MINT, STRING, and/or I2D (see all 238)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016925 | protein sumoylation |
IDA | 17696781 | | GO:0034504 | protein localization to nucleus |
IEA | -- | | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
IEA | -- |
SUMO3 for ontologies About GeneDecksing
|
Drugs & Compounds for SUMO3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for SUMO3 Search CenterWatch for drugs/clinical trials and news about SUMO3 
|
Transcripts for SUMO3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SUMO3 gene: NM_006936.2 Unigene Cluster for SUMO3: SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) Hs.474005 [show with all ESTs]Unigene Representative Sequence: NM_0069368 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000457036 ENST00000427597 ENST00000397898 ENST00000332859(uc002zfz.1 uc011afi.1) ENST00000479153 ENST00000397893 ENST00000466861 ENST00000411651
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUMO3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUMO3 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SUMO3 (NM_006936) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SUMO3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUMO3  |
Additional cDNA sequence: AK222591.1 AK300822.1 AK312350.1 BC000036.2 BC008420.1 BT007008.1 CR542173.1 CR542188.1 X99584.1 19 DOTS entries: DT.75108414 DT.453336 DT.97855480 DT.100846321 DT.95266529 DT.95266510 DT.95266528 DT.100680969 DT.100846306 DT.100846308 DT.100846312 DT.100846313 DT.121136741 DT.121136760 DT.91958452 DT.92456619 DT.92456622 DT.95266508 DT.121136725 24/677 AceView cDNA sequences (see all 677): AA428999 BT007008 BM839975 AA160893 BM784660 BM904363 BM981833 BG767771 CA868421 CA306164 BM989120 BU145945 CR590916 BM683252 BU632464 AI582523 BU535636 BQ918932 AI754040 BI710873 BU684804 AA654096 BM854386 CB110547 GeneLoc Exon Structure
5/14 Alternative Splicing Database (ASD) splice patterns (SP) for SUMO3 (see all 14) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | · | 2f | · | 2g | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | · | 10c | · | 10d | · | 10e | · | |
| SP1: | |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 10f | · | 10g | |
| SP1: | |   | |   | |
| SP2: | |   | |   | |
| SP3: | |   | |   | |
| SP4: | |   | |   | |
| SP5: | |   | |   |
ECgene alternative splicing isoforms for SUMO3
|
Expression for SUMO3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SUMO3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TTCTTCTCGT
About this image See SUMO3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SUMO3
SOURCE GeneReport for Unigene cluster: Hs.474005 UniProtKB/Swiss-Prot: SUMO3_HUMAN, P55854Tissue specificity: Expressed predominantly in liver SABiosciences Custom PCR Arrays for SUMO3
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SUMO3 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SUMO3 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUMO3 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUMO3 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUMO3 |
Orthologs for SUMO3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SUMO3 gene from 7/23 species (see all 23) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
SUMO31 |
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) |
90.32(n) 97.85(a) |
  |
770553 NM_001079498.1 NP_001072966.1 |
lizard (Anolis carolinensis) |
Reptilia |
SUMO36 |
-- |
98(a) |
1 ↔ 1 |
3(33862883-33876067) |
African clawed frog (Xenopus laevis) |
Amphibia |
MGC642972 |
hypothetical protein MGC64297 |
82.5(n) |
  |
BC043947.1 |
zebrafish (Danio rerio) |
Actinopterygii |
wufa94a112 |
Danio rerio cDNA clone MGC65847 IMAGE6797324, complete more |
89.18(n) |
  |
BC058303.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
smt31 |
CG4494-PA |
75.56(n) 74.44(a) |
  |
33981 NM_058063.3 NP_477411.1 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
SUM16SUMO 26(see all 7) |
small ubiquitin-related modifier 2(see all 7) |
47(a)43(a)(see all 7) |
many ↔ manymany ↔ many(see all 7) |
4(13497326-13498730) 5(22383560-22384925) |
rice (Oryza sativa) |
Liliopsida |
Os.247292 |
Transcribed sequence with weak similarity to protein more |
70.81(n) |
  |
CA762495.1 |
ENSEMBL Gene Tree for SUMO3 (if available) TreeFam Gene Tree for SUMO3 (if available)  |
Paralogs for SUMO3 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for SUMO3 gene
- SUMO22 ENSG000002285322 SUMO42 SUMO12
6 SIMAP similar genes for SUMO3 using alignment to 4 protein entries: SUMO3_HUMAN (see all proteins):SUMO2 SUMO4 OK/SW-cl.41 X-linked retinopathy protein NFATC2IP SUMO1
SUMO3 for paralogs About GeneDecksing
5/8 Pseudogenes.org Pseudogenes for SUMO3 (see all 8) PGOHUM00000248128 PGOHUM00000248228 PGOHUM00000248812 PGOHUM00000248815 PGOHUM00000245294
|
Genomic Variants for SUMO3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 21 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for SUMO3 (46191374 - 46238694 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for SUMO3: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SUMO3 |
|
Disorders
/ Diseases for SUMO3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SUMO3 for disorders About GeneDecksing
OMIM gene information: 602231
OMIM disorders: --
14 diseases for SUMO3: About MalaCardsnevoid basal cell carcinoma syndrome transient cerebral ischemia basal cell carcinoma herpes simplex huntington's disease liver disease pancreatic cancer ischemia pancreatitis carcinoma cerebritis immunodeficiency malaria leukemia Human Genome Epidemiology (HuGE) Navigator: SUMO3 (2 documents) Export disorders for SUMO3 gene to outside databases
|
Publications for SUMO3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SUMO3 gene, integrated from 9 sources (see all 127): (articles sorted by number of sources associating them with SUMO3) | |  | Utopia: connect your pdf to the dynamic world of online information |
- SMT3A, a human homologue of the S. cerevisiae SMT3 gene, maps to chromosome 21qter and defines a novel gene family. (PubMed id 9119407)1, 2, 3, 9 Lapenta V....Brahe C. (1997)
- Molecular features of human ubiquitin-like SUMO genes and their encoded proteins. (PubMed id 12383504)1, 2, 9 Su H.-L. and Li S.S.-L. (2002)
- A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex. (PubMed id 15296745)1, 2, 9 Reverter D. and Lima C.D. (2004)
- Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25. (PubMed id 18538659)1, 2 Meulmeester E....Melchior F. (2008)
- Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3. (PubMed id 16608850)1, 2 Gong L. and Yeh E.T.H. (2006)
- The structure of SENP1-SUMO-2 complex suggests a structural basis for discrimination between SUMO paralogues during processing. (PubMed id 16553580)1, 2 Shen L.N.... Hay R.T. (2006)
- Solution structure of human SUMO-3 C47S and its binding surface for Ubc9. (PubMed id 15723523)1, 2 Ding H.... Shi Y. (2005)
- Mapping residues of SUMO precursors essential in differential maturation by SUMO-specific protease, SENP1. (PubMed id 15487983)1, 2 Xu Z. and Au S.W.N. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation. (PubMed id 12924945)1, 2 Tatham M.H.... Chen Y. (2003)
|
External Searches for SUMO3 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SUMO3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SUMO3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SUMO3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SUMO3 | Pharmacogenomics, SNPs, Pathways | | Wikipedia | http://en.wikipedia.org/wiki/SUMO_protein |
|
| | |
About This Section
| Patent Information for SUMO3 gene: Search GeneIP for patents involving SUMO3
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for SUMO3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for SUMO3 | | OriGene shRNA RFP for SUMO3 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SUMO3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SUMO3 | | OriGene Protein Over-expression Lysate for SUMO3 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SUMO3 | | OriGene 3'-UTR Clone for SUMO3 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUMO3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUMO3 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for SUMO3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SUMO3 | | OriGene Custom Protein Services for SUMO3 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SUMO3 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SUMO3 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUMO3 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SUMO3 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUMO3 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUMO3 |
| |
 |  |  |  | |
| Antibodies & Assays for SUMO3  |
| | | Search Tocris compounds for SUMO3 |
| |  |  |  |  | | | | | Recombinant Protein for SUMO3 |
|
 |
 |
 |
 | | SUMO3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUMO3 |
|  |  |  | | | ThermoFisher Antibody for SUMO3 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUMO3 |
|
|
|
|