SUMF2 Gene
protein-coding GIFtS: 52
GCID: GC07P056135
|
|
sulfatase modifying factor 2
| |
Aliases
for SUMF2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Sulfatase Modifying Factor 21 2 | | PFGE1 | | C-Alpha-Formylglycine-Generating Enzyme 22 3 | | Paralog Of The Formylglycine-Generating Enzyme2 | | DKFZp566I10241 | | Sulfatase-Modifying Factor 22 | | C-Alpha-Formyglycine-Generating Enzyme 22 | | |
Export aliases for SUMF2 gene to outside databasesPrevious GC identifers: GC07P055839 GC07P055873 GC07P055906 GC07P056099 GC07P056132 GC07P055946 |
Summaries
for SUMF2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SUMF2:
The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly).The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The genedescribed in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generatingactivity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity.Alternate transcriptional splice variants, encoding different isoforms, have been characterized. (provided by RefSeq,Jul 2008)
UniProtKB/Swiss-Prot: SUMF2_HUMAN, Q8NBJ7Function: Lacks formyl-glycine generating activity and is unable to convert newly synthesized inactive sulfatases totheir active form. Inhibits the activation of sulfatases by SUMF1
Gene Wiki entry for SUMF2
|
Genomic Views
for SUMF2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_033968.6 NT_079592.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SUMF2 gene promoter:
AREB6 GR CREB p53 deltaCREB SEF-1 (1) GR-alpha Nkx2-5
Other transcription factors
Search SABiosciences Chromatin IP Primers for SUMF2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUMF2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q11.1 Ensembl cytogenetic band: 7p11.2 HGNC cytogenetic band: 7q11.1SUMF2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P056135: view genomic region
(about GC identifiers)
Start:
|
56,131,695 bp from pter |
End:
|
56,148,365 bp from pter |
Size:
|
16,671 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 56,136,164-56,152,612 |
|
Proteins
for SUMF2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SUMF2_HUMAN, Q8NBJ7 (See
protein sequence)Recommended Name: Sulfatase-modifying factor 2 precursor Size: 301 amino acids; 33843 Da
Subunit: Homodimer and heterodimer with SUMF1
Subcellular location: Endoplasmic reticulum lumen
Sequence caution: Sequence=AAH00224.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=CAB43247.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=CAB43247.1;Type=Frameshift; Positions=150, 187;
1 PDB 3D structure from  and Proteopedia  for SUMF2:1Y4J (3D)
Secondary accessions: B4DU41 B4DWQ0 Q14DW5 Q53ZE3 Q96BH2 Q9BRN3 Q9BWI1 Q9Y405Alternative splicing: 5 isoforms: Q8NBJ7-1 Q8NBJ7-2 Q8NBJ7-3 Q8NBJ7-5 Q8NBJ7-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SUMF2: NX_Q8NBJ7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NBJ7
SUMF2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001035934.2 NP_001035935.2 NP_001123541.1 NP_001139805.1 NP_056226.2
ENSEMBL proteins: ENSP00000378824 ENSP00000400922 ENSP00000378823 ENSP00000414434 ENSP00000341938 ENSP00000415322 ENSP00000407954 ENSP00000415989 ENSP00000406445 ENSP00000407832 ENSP00000393423 ENSP00000395554 ENSP00000410796 ENSP00000275607 Reactome Protein details: Q8NBJ7
Human Recombinant Protein Products for SUMF2:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005783 | endoplasmic reticulum |
-- | -- | | GO:0005788 | endoplasmic reticulum lumen |
TAS | -- |
SUMF2 for ontologies About GeneDecksing
SUMF2 Antibody Products:
Assay Products for SUMF2: |
Protein
Domains /
Families
for SUMF2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SUMF2 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NBJ7ProtoNet protein and cluster: Q8NBJ7 UniProtKB/Swiss-Prot: SUMF2_HUMAN, Q8NBJ7Similarity: Belongs to the sulfatase-modifying factor family |
Function
for SUMF2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: SUMF2_HUMAN, Q8NBJ7Function: Lacks formyl-glycine generating activity and is unable to convert newly synthesized inactive sulfatases totheir active form. Inhibits the activation of sulfatases by SUMF1 Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
-- | -- | | GO:0042803 | protein homodimerization activity |
-- | -- | | GO:0046872 | metal ion binding |
IEA | -- |
SUMF2 for ontologies About GeneDecksing
Phenotypes:
1 MGI phenotypic allele  for Sumf2 (no phenotypes)
SUMF2 for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUMF2 (see all 9)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUMF2 (see all 6)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 5): SUMF2 (NM_001130069) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SUMF2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUMF2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUMF2 |
|
Pathways & Interactions
for SUMF2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | PTM: gamma carboxylation, hypusine formation and arylsulfatase activation | | | 2 | Asparagine N-linked glycosylation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
4 
Reactome Pathways for SUMF2
SUMF2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SUMF2
4 Interacting proteins for SUMF2 (Q8NBJ72, 3) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0043687 | post-translational protein modification |
TAS | -- | | GO:0044267 | cellular protein metabolic process |
TAS | -- |
SUMF2 for ontologies About GeneDecksing
|
Drugs & Compounds
for SUMF2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SUMF2
Search CenterWatch for drugs/clinical trials and news about SUMF2
|
Transcripts
for SUMF2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SUMF2 gene (7 alternative transcripts): NM_001042469.1 NM_001042470.1 NM_001130069.2 NM_001146333.1 NM_015411.2 NM_001042468.1 NM_001130070.1 Unigene Cluster for SUMF2: Sulfatase modifying factor 2 Hs.279696 [show with all ESTs]Unigene Representative Sequence: CR93675718/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19): ENST00000395436 ENST00000434526(uc011kcw.2 uc003trt.3 uc003trv.3 uc011kcy.2 uc011kcz.2 uc003trx.3 uc011kda.2 uc011kcx.2)
ENST00000395435 ENST00000413952 ENST00000342190 ENST00000452216 ENST00000436782
ENST00000437307 ENST00000413756 ENST00000483327 ENST00000423763 ENST00000498777
ENST00000438133 ENST00000447501(uc011kcv.2) ENST00000451338 ENST00000529457
ENST00000461912 ENST00000531229
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUMF2 (see all 9)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUMF2 (see all 6)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 5): SUMF2 (NM_001130069) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SUMF2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUMF2 |
Additional cDNA sequence: AF075046.1 AK075477.1 AK297042.1 AK297793.1 AK298605.1 AK300488.1 AK301627.1 AY323911.1 AY359103.1 BC006159.1 BC015600.2 BC084539.1 BC111092.1 CR936749.1 CR936757.1 24/44 DOTS entries (see all 44): DT.456309 DT.121122412 DT.95155302 DT.100798368 DT.100798365 DT.100798366 DT.100757357 DT.99965394 DT.121122235 DT.121122521 DT.121122478 DT.121122258 DT.100798363 DT.456310 DT.75150590 DT.100798356 DT.101963614 DT.121122428 DT.91756747 DT.121122262 DT.121122388 DT.121122467 DT.100027741 DT.95155300 24/1112 AceView cDNA sequences (see all 1112): BQ687014 AI089484 BE277276 BF026741 BM460607 BM761679 BQ030353 BQ051163 AA857873 BM480009 BQ213866 BU679755 CA443947 CA438781 AA278281 AI128002 BM905887 AI972550 AI610145 BQ689316 BM791112 AI280553 AA383147 CB132328
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for SUMF2 (see all 11) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | · | 10c | · | 10d | · | 10e | · | 10f |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | - | | | | - | | - | | - | | | | | | - | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | - | | - | | - | | - | | - | | | | | | - | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | - | | - | | | | - | | - | | - | | | | | | - | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SUMF2
|
Expression
for SUMF2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SUMF2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGCCAATAA
About this image
See SUMF2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SUMF2
SOURCE GeneReport for Unigene cluster: Hs.279696
UniProtKB/Swiss-Prot: SUMF2_HUMAN, Q8NBJ7Tissue specificity: Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highestlevels in kidney, liver and placenta
SABiosciences Custom PCR Arrays for SUMF2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SUMF2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SUMF2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUMF2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUMF2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUMF2 |
Orthologs
for SUMF2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for SUMF2 gene from 3/15 species (see all 15) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SUMF21 |
sulfatase modifying factor 2 |
74.14(n)
76.84(a) |
|
417542 XM_415788.3 XP_415788.1 |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.152352 |
Xenopus laevis transcribed sequence with weak similarity more |
72.95(n) |
|
BX848835.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.182072 |
Transcribed sequence with weak similarity to protein more |
77.15(n) |
|
BM572186.1 |
ENSEMBL Gene Tree for SUMF2 (if available)
TreeFam Gene Tree for SUMF2 (if available) |
Paralogs
for SUMF2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SUMF2 gene
- SUMF12
4 SIMAP similar genes for SUMF2 using alignment to 14 protein entries: SUMF2_HUMAN (see all proteins):DKFZP566I1024 GNPTAB SERF1B SUMF1
SUMF2 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for SUMF2
PGOHUM00000260353 PGOHUM00000260359
|
Genomic Variants
for SUMF2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SUMF2 (56131695 - 56148365 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SUMF2
1 CNV: 64828 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SUMF2 |
|
Disorders
/ Diseases
for SUMF2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SUMF2 for disorders About GeneDecksing
OMIM gene information: 607940
OMIM disorders: --
20/24  diseases for SUMF2 (see all 24): About MalaCardsparatyphoid fever typhoid fever legionellosis toxic shock syndrome
ritter's disease campylobacteriosis listeriosis impetigo
macular degeneration osteomyelitis cystic fibrosis mastitis
gastroenteritis shigellosis endocarditis diarrhea
meningitis hepatocellular carcinoma ataxia fibrosis
11 diseases from the University of Copenhagen DISEASES database for SUMF2:Diarrhea Listeriosis Legionellosis Gastroenteritis
Impetigo Shigellosis Mastitis Campylobacteriosis
Pneumonia Cystic fibrosis Meningitis Export disorders for SUMF2 gene to outside databases
|
Publications
for SUMF2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SUMF2 gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with SUMF2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases. (PubMed id 12757706)1, 2, 3 Cosma M.P.... Ballabio A. (2003)
- Sulphatase activities are regulated by the interaction of sulphatase-modifying factor 1 with SUMF2. (PubMed id 15962010)1, 2, 9 Zito E....Cosma M.P. (2005)
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
- Expression, localization, structural, and functional characterization of pFGE, the paralog of the Calpha-formylglycine-generating enzyme. (PubMed id 15708861)1, 2 Mariappan M.... von Figura K. (2005)
- Crystal structure of human pFGE, the paralog of the Calpha- formylglycine-generating enzyme. (PubMed id 15687489)1, 2 Dickmanns A.... Ficner R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- SUMF2 interacts with interleukin-13 and inhibits inte rleukin-13 secretion in bronchial smooth muscle cells. (PubMed id 19739097)1, 9 Liang H....Liu F. (2009)
- The human SUMF1 gene, required for posttranslational sulfatase modification, defines a new gene family which is conserved from pro- to eukaryotes. (PubMed id 14563551)1, 9 Landgrebe J....von Figura K. (2003)
|
External Searches for SUMF2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SUMF2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SUMF2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SUMF2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SUMF2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SUMF2 gene:
Search GeneIP for patents involving SUMF2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SUMF2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SUMF2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SUMF2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SUMF2 | | | OriGene Protein Over-expression Lysate for SUMF2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SUMF2 | | OriGene 3'-UTR Clone for SUMF2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUMF2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUMF2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SUMF2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SUMF2 | | OriGene Custom Protein Services for SUMF2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SUMF2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SUMF2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUMF2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SUMF2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUMF2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUMF2 |
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| | | | Search Tocris compounds for SUMF2 |
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 | | | SUMF2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUMF2 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for SUMF2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUMF2 |
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