SUMF1 Gene
protein-coding GIFtS: 59
GCID: GC03M003742
|
|
sulfatase modifying factor 1
| |
Aliases for SUMF1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Sulfatase Modifying Factor 11 2 | | AAPA30372 | | FGE1 2 3 5 | | FGly-Generating Enzyme2 | | C-Alpha-Formylglycine-Generating Enzyme 12 3 | | Sulfatase-Modifying Factor 12 | | UNQ30371 | | EC 1.8.99.-3 |
Export aliases for SUMF1 gene to outside databasesPrevious GC identifers: GC03M004394 GC03M004377 GC03M003844 |
Summaries for SUMF1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for SUMF1: This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in thesubstrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations inthis gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multipletranscript variants. (provided by RefSeq, Sep 2009) UniProtKB/Swiss-Prot: SUMF1_HUMAN, Q8NBK3Function: Using molecular oxygen and an unidentified reducing agent, oxidizes a cysteine residue in the substratesulfatase to an active site 3-oxoalanine residue, which is also called C(alpha)-formylglycine. Known substratesinclude GALNS, ARSA, STS and ARSE Gene Wiki entry for SUMF1
|
Genomic Views for SUMF1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SUMF1 gene promoter: USF1 Pax-5 ATF-2 C/EBPalpha CRE-BP1 USF-1 Sox9 IRF-7A aMEF-2 NF-kappaB1 Other transcription factors
Search SABiosciences Chromatin IP Primers for SUMF1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUMF1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p26.1 Ensembl cytogenetic band: 3p26.1 HGNC cytogenetic band: 3p26.1SUMF1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M003742: view genomic region
(about GC identifiers)
Start:
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3,742,498 bp from pter |
End:
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4,508,966 bp from pter |
Size:
|
766,469 bases |
Orientation:
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minus strand |
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Proteins for SUMF1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SUMF1_HUMAN, Q8NBK3 (See
protein sequence)Recommended Name: Sulfatase-modifying factor 1 precursor Size: 374 amino acids; 40556 Da
Subunit: Monomer, homodimer and heterodimer with SUMF2
Subcellular location: Endoplasmic reticulum lumen
Miscellaneous: The resulting 3-oxoalanine in the substrate protein is called C(alpha)-formylglycine by many authors. Itshould not be confused with N-formylglycine
6/14 PDB 3D structures from and Proteopedia for SUMF1 (see all 14):1Y1E (3D)
  1Y1F (3D)
  1Y1G (3D)
  1Y1H (3D)
  1Y1I (3D)
  1Y1J (3D)
 
Secondary accessions: B4DXK5 B7XD05 E9PGL0 G5E9B0 Q0VAC6 Q0VAC7 Q2NL78 Q53ZE4 Q6UY39 Q96AK5 Q96DK8Alternative splicing: 5 isoforms: Q8NBK3-1 Q8NBK3-2 Q8NBK3-3 Q8NBK3-4 Q8NBK3-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SUMF1: NX_Q8NBK3
Post-translational modifications:
N-glycosylated. Contains high-mannose-type oligosaccharides1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NBK3 SUMF1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001158146.1 NP_001158147.1 NP_877437.2 ENSEMBL proteins: ENSP00000404384 ENSP00000272902 ENSP00000373355 ENSP00000410060 ENSP00000384977 ENSP00000440421 Reactome Protein details: Q8NBK3 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005783 | endoplasmic reticulum |
-- | -- | | GO:0005788 | endoplasmic reticulum lumen |
TAS | -- |
SUMF1 for ontologies About GeneDecksing
SUMF1 Antibody Products: Assay Products for SUMF1: |
Protein
Domains / Families for SUMF1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SUMF1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NBK3ProtoNet protein and cluster: Q8NBK3 UniProtKB/Swiss-Prot: SUMF1_HUMAN, Q8NBK3Similarity: Belongs to the sulfatase-modifying factor family |
Function for SUMF1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: SUMF1_HUMAN, Q8NBK3Function: Using molecular oxygen and an unidentified reducing agent, oxidizes a cysteine residue in the substratesulfatase to an active site 3-oxoalanine residue, which is also called C(alpha)-formylglycine. Known substratesinclude GALNS, ARSA, STS and ARSECatalytic activity: [sulfatase]-cysteine + acceptor = [sulfatase]-3-oxoalanine + reduced acceptorEnzyme Number (IUBMB): EC 1.8.99.-1
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUMF1 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUMF1 (see all 4) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): SUMF1 (NM_182760) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SUMF1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUMF1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUMF1 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
SUMF1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SUMF1: Animal Models: Mouse knock-out Sumf1tm1Lex for SUMF1 11 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Sumf1):
SUMF1 for phenotypes About GeneDecksing
|
Pathways & Interactions for SUMF1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Sphingolipid metabolism | | | 2 | PTM: gamma carboxylation, hypusine formation and arylsulfatase activation | | | 3 | Metabolism | | | 4 | Asparagine N-linked glycosylation | | | 5 | Lysosome | |
Pathway sources See GeneCards unified pathways Show all pathways
5/8
Reactome Pathways for SUMF1 (see all 8)
1
Kegg Pathway (Kegg details for SUMF1): UniProtKB/Swiss-Prot: SUMF1_HUMAN, Q8NBK3Pathway: Protein modification; sulfatase oxidation
SUMF1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SUMF1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/29 Interacting proteins for SUMF1 (Q8NBK32, 3 ENSP000002729024) via UniProtKB, MINT, STRING, and/or I2D (see all 29) About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006644 | phospholipid metabolic process |
TAS | -- | | GO:0006665 | sphingolipid metabolic process |
TAS | -- | | GO:0006687 | glycosphingolipid metabolic process |
TAS | -- | | GO:0043687 | post-translational protein modification |
TAS | -- | | GO:0044267 | cellular protein metabolic process |
TAS | -- |
SUMF1 for ontologies About GeneDecksing
|
Drugs & Compounds for SUMF1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SUMF1 for compounds About GeneDecksing
Browse Tocris compounds for SUMF1 4 Novoseek chemical compound relationships for SUMF1 gene About this table
Search CenterWatch for drugs/clinical trials and news about SUMF1 
|
Transcripts for SUMF1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SUMF1 gene (3 alternative transcripts): NM_001164674.1 NM_001164675.1 NM_182760.3 Unigene Cluster for SUMF1: Sulfatase modifying factor 1 Hs.350475 [show with all ESTs]Unigene Representative Sequence: NM_1827609 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000470751 ENST00000448413(uc003bps.2) ENST00000469888 ENST00000484993 ENST00000272902(uc003bpz.2 uc011ass.2 uc010hby.2 uc011ast.2) ENST00000383843 ENST00000458465 ENST00000405420 ENST00000534863
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUMF1 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUMF1 (see all 4) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): SUMF1 (NM_182760) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SUMF1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUMF1  |
Additional cDNA sequence: AB448737.1 AK057983.1 AK075459.1 AK094111.1 AK295240.1 AK302018.1 AY208752.1 AY323910.1 BC017005.2 BC110862.1 BC121122.2 BC121123.2 10 DOTS entries: DT.100782200 DT.112739 DT.91740147 DT.120874400 DT.100782201 DT.120874382 DT.100839533 DT.100024584 DT.100763768 DT.100701154 24/112 AceView cDNA sequences (see all 112): AI347010 BX381448 BX379410 AA195080 CR615481 AY208752 AI873170 BX403255 BQ683180 AA905255 NM_182760 AY323910 BF725507 BE271837 BX349149 BU628423 AI627833 CA425710 CF529064 AI767341 AI471443 AW183622 AW237610 BQ005985 GeneLoc Exon Structure
|
Expression for SUMF1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SUMF1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CACTGTGTTG
About this image See SUMF1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SUMF1
SOURCE GeneReport for Unigene cluster: Hs.350475 UniProtKB/Swiss-Prot: SUMF1_HUMAN, Q8NBK3Tissue specificity: Ubiquitous. Highly expressed in kidney, pancreas and liver. Detected at lower levels in leukocytes,lung, placenta, small intestine, skeletal muscle and heart SABiosciences Custom PCR Arrays for SUMF1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SUMF1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SUMF1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUMF1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUMF1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUMF1 |
Orthologs for SUMF1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SUMF1 gene from 6/20 species (see all 20) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Sumf11 , 5 |
sulfatase modifying factor 11, 5 |
84.59(n)1 86.56(a)1 |
  |
6 (49.71 cM)5 589111 NM_145937.31 NP_666049.21 1081070285 |
chicken (Gallus gallus) |
Aves |
LOC1008592611 |
sulfatase-modifying factor 1-like |
73.14(n) 76.47(a) |
  |
100859261 XM_003642022.1 XP_003642070.1 |
lizard (Anolis carolinensis) |
Reptilia |
SUMF16 |
-- |
81(a) |
1 ↔ 1 |
2(173489996-173574647) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.155282 |
Xenopus laevis transcribed sequence with weak similarity more |
78.37(n) |
  |
BJ054666.1 |
zebrafish (Danio rerio) |
Actinopterygii |
wufd20g042 |
Transcribed sequences |
74.72(n) |
  |
57056785 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG70491 |
CG7049 |
56.94(n) 57.7(a) |
  |
38022 NM_138159.3 NP_612003.1 |
ENSEMBL Gene Tree for SUMF1 (if available) TreeFam Gene Tree for SUMF1 (if available)  |
Paralogs for SUMF1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for SUMF1 gene
- SUMF22
2 SIMAP similar genes for SUMF1 using alignment to 3 protein entries: SUMF1_HUMAN (see all proteins):DKFZP566I1024 SUMF2
SUMF1 for paralogs About GeneDecksing
|
Genomic Variants for SUMF1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 3 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for SUMF1 (3742498 - 3992498 bp, first 250kb of SUMF1)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for SUMF1 1 CNV: 3416 Human Gene Mutation Database (HGMD): SUMF1
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SUMF1 |
|
Disorders
/ Diseases for SUMF1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SUMF1 for disorders About GeneDecksing
OMIM gene information: 607939 OMIM disorders: 272200 UniProtKB/Swiss-Prot: SUMF1_HUMAN, Q8NBK3
Defects in SUMF1 are the cause of multiple sulfatase deficiency (MSD) [MIM:272200]. MSD is a clinically andbiochemically heterogeneous disorder caused by the simultaneous impairment of all sulfatases, due to defectivepost-translational modification and activation. It combines features of individual sulfatase deficiencies such asmetachromatic leukodystrophy, mucopolysaccharidosis, chondrodysplasia punctata, hydrocephalus, ichthyosis, neurologicdeterioration and developmental delay. Inheritance is autosomal recessive 17 diseases for SUMF1: About MalaCardsx-linked ichthyosis lysosomal storage disease metachromatic leukodystrophy chondrodysplasia punctata mucolipidosis ii mucolipidosis leukodystrophy chondrodysplasia ichthyosis spinocerebellar ataxia mucopolysaccharidosis multiple sclerosis ataxia neurodegeneration retinitis tuberculosis mycobacterium tuberculosis 3 diseases from the University of Copenhagen DISEASES database for SUMF1:Mucopolysaccharidosis Metachromatic leukodystrophy X-linked ichthyosis 3 Novoseek disease relationships for SUMF1 gene About this table
Human Genome Epidemiology (HuGE) Navigator: SUMF1 (1 document) Export disorders for SUMF1 gene to outside databases
|
Publications for SUMF1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SUMF1 gene, integrated from 9 sources (see all 52): (articles sorted by number of sources associating them with SUMF1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Multiple sulfatase deficiency is caused by mutations in the gene encoding the Homo sapiens C-alpha-formyglycine-generating enzyme. (PubMed id 12757705)1, 2, 3, 9 Dierks T.... von Figura K. (2003)
- The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases. (PubMed id 12757706)1, 2, 3 Cosma M.P.... Ballabio A. (2003)
- Molecular analysis of SUMF1 mutations: stability and residual activity of mutant formylglycine-generating enzyme determine disease severity in multiple sulfatase deficiency. (PubMed id 18157819)1, 2, 9 Schlotawa L.... Gaertner J. (2008)
- A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme. (PubMed id 16368756)1, 2, 9 Roeser D.... Rudolph M.G. (2006)
- Molecular characterization of the human Calpha-formylglycine- generating enzyme. (PubMed id 15657036)1, 2, 9 Preusser-Kunze A.... Dierks T. (2005)
- Sulphatase activities are regulated by the interaction of sulphatase-modifying factor 1 with SUMF2. (PubMed id 15962010)1, 2, 9 Zito E....Cosma M.P. (2005)
- Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme. (PubMed id 15907468)1, 2, 9 Dierks T.... Rudolph M.G. (2005)
- Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19. (PubMed id 19262745)1, 2, 9 Oshikawa M.... Kato S. (2009)
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
|
External Searches for SUMF1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SUMF1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SUMF1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SUMF1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SUMF1 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/SUMF1 |
|
| | |
About This Section
| Patent Information for SUMF1 gene: Search GeneIP for patents involving SUMF1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for SUMF1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for SUMF1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SUMF1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SUMF1 | | OriGene Protein Over-expression Lysate for SUMF1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SUMF1 | | OriGene 3'-UTR Clone for SUMF1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUMF1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUMF1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for SUMF1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SUMF1 | | OriGene Custom Protein Services for SUMF1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SUMF1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SUMF1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUMF1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SUMF1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUMF1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUMF1 |
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| | | Search Tocris compounds for SUMF1 |
| |  |  |  |  | | | | | Recombinant Protein for SUMF1 |
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 | | SUMF1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUMF1 |
|  |  |  | | | ThermoFisher Antibody for SUMF1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUMF1 |
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