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SULT4A1 Gene

protein-coding   GIFtS: 58
GCID: GC22M044220

Sulfotransferase Family 4A, Member 1

  See SULT4A1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sulfotransferase Family 4A, Member 11 2     BRSTL12 5
Brain Sulfotransferase-Like Protein2 3     BR-STL-12
Nervous System Sulfotransferase2 3     DJ388M5.32
NST2 3     Nervous System Cytosolic Sulfotransferase2
ST4A12 3     Sulfotransferase 4A12
SULTX32 3     Sulfotransferase-Related Protein2
hBR-STL2 3     EC 2.8.2.-3
hBR-STL-12 3     

External Ids:    HGNC: 149031   Entrez Gene: 258302   Ensembl: ENSG000001305407   OMIM: 6083595   UniProtKB: Q9BR013   

Export aliases for SULT4A1 gene to outside databases

Previous GC identifers: GC22M040837 GC22M042478 GC22M042545 GC22M042551 GC22M027174


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SULT4A1 Gene:
This gene encodes a member of the sulfotransferase family. The encoded protein is a brain-specific
sulfotransferase believed to be involved in the metabolism of neurotransmitters. Polymorphisms in this gene may
be associated with susceptibility to schizophrenia. (provided by RefSeq, Jul 2008)

GeneCards Summary for SULT4A1 Gene:
SULT4A1 (sulfotransferase family 4A, member 1) is a protein-coding gene. Diseases associated with SULT4A1 include schizotypal personality disorder, and schizophrenia. GO annotations related to this gene include sulfotransferase activity. An important paralog of this gene is SULT1C3.

UniProtKB/Swiss-Prot: ST4A1_HUMAN, Q9BR01
Function: Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS)
and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine,
and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS

Gene Wiki entry for SULT4A1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000022.10  NC_018933.2  NT_011520.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the SULT4A1 gene promoter:
         SREBP-1c   NRSF form 1   Olf-1   E4BP4   NRSF form 2   SREBP-1b   HEN1   AREB6   SREBP-1a   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSULT4A1 promoter sequence
   Search Chromatin IP Primers for SULT4A1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SULT4A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.2   Ensembl cytogenetic band:  22q13.31   HGNC cytogenetic band: 22q13.2

SULT4A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SULT4A1 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M044220:  view genomic region     (about GC identifiers)

Start:
44,220,387 bp from pter      End:
44,258,398 bp from pter
Size:
38,012 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ST4A1_HUMAN, Q9BR01 (See protein sequence)
Recommended Name: Sulfotransferase 4A1  
Size: 284 amino acids; 33085 Da
1 PDB 3D structure from and Proteopedia for SULT4A1:
1ZD1 (3D)    
Secondary accessions: B2R7N3 O43728
Alternative splicing: 2 isoforms:  Q9BR01-1   Q9BR01-2   

Explore the universe of human proteins at neXtProt for SULT4A1: NX_Q9BR01

Explore proteomics data for SULT4A1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SULT4A1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055166.1  
    ENSEMBL proteins: 
     ENSP00000332565   ENSP00000414220   ENSP00000388285   ENSP00000439141   ENSP00000249130  
    Reactome Protein details: Q9BR01

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SULT: Sulfotransferases, cytosolic

    2 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR000863 Sulfotransferase_dom

    Graphical View of Domain Structure for InterPro Entry Q9BR01

    ProtoNet protein and cluster: Q9BR01

    1 Blocks protein domain: IPB000863 Sulfotransferase

    UniProtKB/Swiss-Prot: ST4A1_HUMAN, Q9BR01
    Similarity: Belongs to the sulfotransferase 1 family


    Find genes that share domains with SULT4A1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ST4A1_HUMAN, Q9BR01
    Function: Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS)
    and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine,
    and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS

         Enzyme Number (IUBMB): EC 2.8.2.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19439498
    GO:0008146sulfotransferase activity NAS10698717
         
    Find genes that share ontologies with SULT4A1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SULT4A1:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SULT4A1
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    hsa-miR-125a-5p hsa-miR-448 hsa-miR-888* hsa-miR-511 hsa-miR-144 hsa-miR-125b hsa-miR-3121-3p hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidSULT4A1 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SULT4A1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ST4A1_HUMAN, Q9BR01: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus2
    extracellular1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005829cytosol TAS--

    Find genes that share ontologies with SULT4A1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SULT4A1 About    
    See pathways by source

    SuperPathContained pathways About
    1Biological oxidations
    Biological oxidations0.56
    metapathway biotransformation0.42
    Phase II conjugation0.56
    Cytosolic sulfonation of small molecules0.00
    2Metabolism
    Metabolism0.38
    3Sulfation Biotransformation Reaction
    Sulfation Biotransformation Reaction


    Find genes that share SuperPaths with SULT4A1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for SULT4A1
        Sulfation Biotransformation Reaction
    metapathway biotransformation

    1 Reactome Pathway for SULT4A1
        Cytosolic sulfonation of small molecules


        Pathway & Disease-focused RT2 Profiler PCR Array including SULT4A1: 
              Drug Metabolism: Phase II Enzymes in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for SULT4A1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for SULT4A1 (Q9BR011 ENSP000003325654) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PIN1Q135261EBI-6690555,EBI-714158
    POT1ENSP000003502494STRING: ENSP00000350249
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006790sulfur compound metabolic process ----
    GO:0006805xenobiotic metabolic process TAS--
    GO:0008150biological_process ND--
    GO:0008202steroid metabolic process IEA--
    GO:0044281small molecule metabolic process TAS--

    Find genes that share ontologies with SULT4A1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SULT4A1 (ST4A1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SULT4A1 gene (2 alternative transcripts): 
    NM_014351.3  NM_176874.1  

    Unigene Cluster for SULT4A1:

    Sulfotransferase family 4A, member 1
    Hs.189810  [show with all ESTs]
    Unigene Representative Sequence: BC030665
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000330884(uc003bed.1 uc003bee.1 uc011aqb.1) ENST00000432404
    ENST00000422525(uc003bef.1) ENST00000475131 ENST00000540422 ENST00000249130

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SULT4A1 (see all 20):
    hsa-miR-125a-5p hsa-miR-448 hsa-miR-888* hsa-miR-511 hsa-miR-144 hsa-miR-125b hsa-miR-3121-3p hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidSULT4A1 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat SULT4A1
      QuantiFast Probe-based Assays in human, mouse, rat SULT4A1

    Additional mRNA sequence: 

    AF115311.1 AF176342.1 AF188698.1 AF251263.1 AK294622.1 AK295399.1 AK313048.1 AL590119.1 
    BC022459.1 BC030665.1 CR456588.1 

    7 DOTS entries:

    DT.313629  DT.100018277  DT.100018275  DT.95375673  DT.97778149  DT.95375675  DT.120667003 

    Selected AceView cDNA sequences (see all 102):

    AI203296 Z38771 AL590119 BF980693 CB153723 AF251263 CR456588 AA351518 
    AA322123 AF176342 AA330927 AF115311 BM711982 AI638833 AF188698 BI600806 
    CK002566 BX436262 BI544258 BI597652 AI815496 BI544359 CD625600 BI550483 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SULT4A1 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b · 9c · 9d
    SP1:                                                                                          
    SP2:                                                              -                           
    SP3:        -                                                                                 
    SP4:              -                                                                           
    SP5:              -     -     -                                   -                           


    ECgene alternative splicing isoforms for SULT4A1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SULT4A1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SULT4A1 Expression
    About this image


    SULT4A1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 8 entries
             Mature Choroid Plexus Cells Choroid Plexus
             Cerebral Cortex
             Temporal Lobe   
     
     Epithelial Cells
             Mature Choroid Plexus Cells Choroid Plexus
     
     Endothelium (Cardiovascular System)
             Mature Endothelial Cells Blood Brain Barrier
    SULT4A1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SULT4A1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.189810

    UniProtKB/Swiss-Prot: ST4A1_HUMAN, Q9BR01
    Tissue specificity: Highly expressed in the cerebral cortex and frontal lobe, slightly less in the cerebellum,
    occipital and temporal lobes, relatively low in the medulla and putamen, and lowest in the spinal cord. No
    expression detected in the pancreas (PubMed:10698717). Highly expressed in fetal brain and occipital lobe,
    slightly less in the whole brain, frontal lobe, hippocampus, and lung, very low expression in cerebellum, medulla
    oblongata, temporal lobe, testis, kidney and appendix (PubMed:12039030)

        Pathway & Disease-focused RT2 Profiler PCR Array including SULT4A1: 
              Drug Metabolism: Phase II Enzymes in human mouse rat

    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat SULT4A1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SULT4A1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SULT4A1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sult4a11 , 5 sulfotransferase family 4A, member 11, 5 91.55(n)1
    97.89(a)1
      15 (39.73 cM)5
    298591  NM_013873.31  NP_038901.31 
     840760975 
    chicken
    (Gallus gallus)
    Aves SULT4A11 sulfotransferase family 4A, member 1 79.91(n)
    94.32(a)
      418232  XM_416456.4  XP_416456.4 
    lizard
    (Anolis carolinensis)
    Reptilia SULT4A16
    sulfotransferase family 4A, member 1
    95(a)
    1 ↔ 1
    5(85959178-85985181)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia sult4a11 sulfotransferase family 4A, member 1 79.23(n)
    90.49(a)
      779775  NM_001078854.1  NP_001072322.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.192152 Transcribed sequence with moderate similarity to protein more 83.3(n)    BI533409.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG167333 aryl sulfotransferase 33(a)
    (best of 3)
      85D4   --


    ENSEMBL Gene Tree for SULT4A1 (if available)
    TreeFam Gene Tree for SULT4A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SULT4A1 gene
    SULT1C32  SULT1B12  SULT1A22  SULT1C42  SULT1C22  SULT1E12  SULT2B12  SULT1A42  
    SULT2A12  SULT6B12  SULT1A12  SULT1A32  
    13 SIMAP similar genes for SULT4A1 using alignment to 3 protein entries:     ST4A1_HUMAN (see all proteins):
    STP1    SULT1A2    SULT1B1    ST1A5    SULT1A3    SULT1A4
    SULT1C2    SULT1C3    SULT1A1    SULT1E1    SULT2A1    SULT6B1
    SULT1C4

    Find genes that share paralogs with SULT4A1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SULT4A1 (see all 968)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs607469171,2
    C--28170920(+) AAAAA-/AAAGGAAA 1 -- int11Minor allele frequency- AAA:0.00NA 2
    rs1885656911,2
    --28177941(+) AAGGAA/GAGTAC 1 -- int10--------
    rs1381121,2
    C,F,A,H--28177962(+) taaaaT/Cgtctt 1 -- int124Minor allele frequency- C:0.24NS EA NA WA CSA 2770
    rs41494451,2
    C,F,H--44219944(-) CCTGAT/GTTCCT 1 -- ds500122Minor allele frequency- G:0.13NS EA NA WA 2762
    rs1920150381,2
    --44219953(+) GGAAGA/GCAGGC 1 -- ds50010--------
    rs1839045851,2
    --44220003(+) GCCTCA/GGGCAC 1 -- ds50010--------
    rs1502657661,2
    --44220017(+) AGTGCA/GCAACG 1 -- ds50010--------
    rs20669141,2
    H--44220031(+) AACACA/CGGGCT 1 -- ds50014Minor allele frequency- C:0.00NS EA 420
    rs776396721,2
    F--44220060(+) GGTCCC/TGACAC 1 -- ds50011Minor allele frequency- T:0.06WA 118
    rs20669151,2
    C,F,A,H--44220143(+) AGAGGT/CGAATG 1 -- ds500118Minor allele frequency- C:0.34NS EA NA WA CSA 2147

    HapMap Linkage Disequilibrium report for SULT4A1 (44220387 - 44258398 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SULT4A1 (see all 19):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1523199CNV Deletion17803354
    esv2724329CNV Deletion23290073
    esv2724327CNV Deletion23290073
    esv1037241CNV Deletion17803354
    esv2510122CNV Deletion19546169
    esv1538910CNV Deletion17803354
    nsv3647CNV Loss18451855
    nsv834218CNV Loss17160897
    nsv829265CNV Loss20364138
    dgv4998n71CNV Loss21882294

    Human Gene Mutation Database (HGMD): SULT4A1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SULT4A1
    DNA2.0 Custom Variant and Variant Library Synthesis for SULT4A1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608359    OMIM disorders: --

    2 diseases for SULT4A1:    
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    schizotypal personality disorder    schizophrenia

    1 disease from the University of Copenhagen DISEASES database for SULT4A1:
    Schizotypal personality disorder

    Find genes that share disorders with SULT4A1           About GenesLikeMe

    Genetic Association Database (GAD): SULT4A1
    Human Genome Epidemiology (HuGE) Navigator: SULT4A1 (6 documents)

    Export disorders for SULT4A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SULT4A1 gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with SULT4A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and expression of novel sulphotransferase-like cDNAs from human and rat brain. (PubMed id 10698717)1, 2, 3, 9 Falany C.N.... Falany J.L. (Biochem. J. 2000)
    2. Lack of exonic sulfotransferase 4A1 mutations in controls and schizophrenia cases. (PubMed id 19125109)1, 4, 9 Lewis A.G. and Minchin R.F. (Psychiatr. Genet. 2009)
    3. Association of Sult4A1 SNPs with psychopathology and cognition in patients with schizophrenia or schizoaffective disorder. (PubMed id 18823757)1, 4, 9 Meltzer H.Y....Jayathilake K. (Schizophr. Res. 2008)
    4. MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer. (PubMed id 20819778)1, 4 Zhang X....Wu X. (Carcinogenesis 2010)
    5. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1, 4 Saito A....Kamatani N. (J. Hum. Genet. 2009)
    6. Structural and chemical profiling of the human cytosolic sulfotransferases. (PubMed id 17425406)1, 2 Allali-Hassani A.... Arrowsmith C.H. (PLoS Biol. 2007)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (Genome Biol. 2004)
    10. Reevaluating human gene annotation: a second-generation analysis of chromosome 22. (PubMed id 12529303)1, 2 Collins J.E.... Dunham I. (Genome Res. 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25830 HGNC: 14903 AceView: SULT4A1 Ensembl:ENSG00000130540 euGenes: HUgn25830
    ECgene: SULT4A1 H-InvDB: SULT4A1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SULT4A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SULT4A1 gene:
    Search GeneIP for patents involving SULT4A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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