Aliases for SULT2A1 Gene
External Ids for SULT2A1 Gene
Previous HGNC Symbols for SULT2A1 Gene
Previous GeneCards Identifiers for SULT2A1 Gene
This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome. [provided by RefSeq, Mar 2010]
GeneCards Summary for SULT2A1 Gene
SULT2A1 (Sulfotransferase Family 2A Member 1) is a Protein Coding gene. Diseases associated with SULT2A1 include Selective T-Cell Defect and Polycystic Ovary Syndrome. Among its related pathways are Estrogen Metabolism Pathway and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). GO annotations related to this gene include sulfotransferase activity and bile-salt sulfotransferase activity. An important paralog of this gene is SULT2B1.
UniProtKB/Swiss-Prot for SULT2A1 Gene
Sulfotransferase that utilizes 3-phospho-5-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands.