Aliases for SULT1C2 Gene
External Ids for SULT1C2 Gene
Previous Symbols for SULT1C2 Gene
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for SULT1C2 Gene
SULT1C2 (Sulfotransferase Family, Cytosolic, 1C, Member 2) is a Protein Coding gene. Among its related pathways are Metabolism and Biological oxidations. GO annotations related to this gene include sulfotransferase activity. An important paralog of this gene is SULT1B1.
UniProtKB/Swiss-Prot for SULT1C2 Gene
Sulfotransferase that utilizes 3-phospho-5-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF)