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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SULT1C2 Gene

protein-coding GIFtS: 57
GCID: GC02P108905

sulfotransferase family, cytosolic, 1C, member 2

(Previous names: sulfotransferase family, cytosolic, 1C, member 1 )
(Previous symbol: SULT1C1)

Explore 8 diseases affiliated with
SULT1C2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Sulfotransferase Family, Cytosolic, 1C, Member 2¹ ²		HumSULTC2¹
SULT1C1¹ ² ³ ⁵		Sulfotransferase 1C2²
ST1C1¹ ²		EC 2.8.2.-³
Sulfotransferase Family, Cytosolic, 1C, Member 1¹ ²		EC 2.8.2⁸
Sulfotransferase 1C1² ³		EC 2.8.2.1⁸
ST1C2² ³		EC 2.8.2.2⁸
SULT1C#1² ³

External Ids:	HGNC: 11456¹	Entrez Gene: 6819²	Ensembl: ENSG00000198203⁷	OMIM: 602385⁵	UniProtKB: O00338³

Export aliases for SULT1C2 gene to outside databases

Previous GC identifers: GC02P106899 GC02P107474 GC02P108469 GC02P108486 GC02P108488 GC02P108452 GC02P108272 GC02P102504

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SULT1C2:

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic

compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene

structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to

the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Two

alternatively spliced transcript variants encoding different isoforms have been described for this gene. (provided by

RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ST1C2_HUMAN, O00338

Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the

sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation

of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF)

Gene Wiki entry for SULT1C2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_022171.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SULT1C2 gene promoter:
GR Pbx1a AP-4 CUTL1 C/EBPalpha YY1 Zic1 GR-alpha ZIC2/Zic2 Zic3
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SULT1C2 promoter sequence

Search SABiosciences Chromatin IP Primers for SULT1C2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SULT1C2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q12.3 Ensembl cytogenetic band: 2q12.3 HGNC cytogenetic band: 2q12.3

SULT1C2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SULT1C2 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P108905: view genomic region (about GC identifiers)

Start:	108,905,095 bp from pter	End:	108,926,371 bp from pter
Size:	21,277 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ST1C2_HUMAN, O00338 (See protein sequence)

Recommended Name: Sulfotransferase 1C2

Size: 296 amino acids; 34880 Da

Subcellular location: Cytoplasm

1 PDB 3D structure from and Proteopedia for SULT1C2:

3BFX (3D)

Secondary accessions: B2R813 Q53SG4

Alternative splicing: 2 isoforms: O00338-1 O00338-2

Explore the universe of human proteins at neXtProt for SULT1C2: NX_O00338

4/10 DME Specific Peptides for SULT1C2 (O00338) (see all 10)

RHPFIEW

FTVAQNE

ETSFEKMK

SFWENNCK

SULT1C2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001047.1 NP_789795.1

ENSEMBL proteins:

ENSP00000251481 ENSP00000319622 ENSP00000401996 ENSP00000387054 ENSP00000399651

ENSP00000415194 ENSP00000387340

Reactome Protein details: O00338
Human Recombinant Protein Products for SULT1C2:

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	Novus Biologicals SULT1C2 Proteins Novus Biologicals SULT1C2 Lysates
	Browse Sino Biological Recombinant Proteins
	ProSpec Recombinant Protein for SULT1C2
	Uscn Proteins for SULT1C2

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	TAS	9169148
GO:0005829	cytosol	TAS	--
GO:0015630	microtubule cytoskeleton	IDA	--

SULT1C2 for ontologies About GeneDecksing

SULT1C2 Antibody Products:

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Assay Products for SULT1C2:

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	Uscn ELISAs and CLIAs for SULT1C2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SULT1C2 for domains About GeneDecksing

1 InterPro domain/family:

IPR000863 Sulfotransferase_dom

Graphical View of Domain Structure for InterPro Entry O00338

ProtoNet protein and cluster: O00338

1 Blocks protein family: IPB000863 Sulfotransferase

UniProtKB/Swiss-Prot: ST1C2_HUMAN, O00338

Similarity: Belongs to the sulfotransferase 1 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: ST1C2_HUMAN, O00338

Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the

sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation

of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF)

Enzyme Numbers (IUBMB): EC 2.8.2.-¹ EC 2.8.2² EC 2.8.2.2² EC 2.8.2.1²

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008146	sulfotransferase activity	IDA	--

SULT1C2 for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SULT1C2

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SULT1C2
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate SULT1C2:
		hsa-miR-127-5p hsa-miR-186
		SwitchGear 3'UTR luciferase reporter plasmid: SULT1C2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SULT1C2 (see all 4) OriGene shRNA RFP: SULT1C2 OriGene siRNA: SULT1C2
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Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for SULT1C2
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Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SULT1C2 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SULT1C2 (see all 3) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): SULT1C2 (NM_001056)
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SULT1C2

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Biological oxidations

	Biological oxidations	1.00			metapathway biotransformation	0.41
	Phase II conjugation	0.52

Cytosolic sulfonation of small molecules

Cytosolic sulfonation of small molecules

1.00

Sulfation Biotransformation Reaction

0.67

Metabolism

Metabolism

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

2 BioSystems Pathways for SULT1C2

	Sulfation Biotransformation Reaction
	metapathway biotransformation

4 Reactome Pathways for SULT1C2

	Metabolism
	Biological oxidations
	Cytosolic sulfonation of small molecules
	Phase II conjugation

SULT1C2 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SULT1C2

STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

5/6 Interacting proteins for SULT1C2 (ENSP00000319622⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 6)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ACD	ENSP00000377496⁴	STRING: ENSP00000377496
POT1	ENSP00000350249⁴	STRING: ENSP00000350249
TERF1	ENSP00000276603⁴	STRING: ENSP00000276603
TINF2	ENSP00000267415⁴	STRING: ENSP00000267415
HLTF	ENSP00000308944⁴	STRING: ENSP00000308944

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006805	xenobiotic metabolic process	TAS	--
GO:0009308	amine metabolic process	TAS	9169148
GO:0044281	small molecule metabolic process	TAS	--
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	TAS	--
GO:0051923	sulfation	IDA	--

SULT1C2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

SULT1C2 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SULT1C2
1 Novoseek chemical compound relationship for SULT1C2 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
n-hydroxy-2-acetylaminofluorene	86.7	2	9202764 (1)

Search CenterWatch for drugs/clinical trials and news about SULT1C2 / ST1C2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SULT1C2 gene (2 alternative transcripts):

NM_001056.3 NM_176825.2

Unigene Cluster for SULT1C2:

Sulfotransferase family, cytosolic, 1C, member 2

Hs.436123 [show with all ESTs]

Unigene Representative Sequence: NM_176825

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000251481(uc010ywp.1 uc002tdy.3 uc010ywq.2) ENST00000326853(uc002tdx.3)

ENST00000438339 ENST00000409880 ENST00000437390 ENST00000442801 ENST00000409067

ENST00000492554 ENST00000495441

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SULT1C2
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate SULT1C2:
		hsa-miR-127-5p hsa-miR-186
		SwitchGear 3'UTR luciferase reporter plasmid: SULT1C2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SULT1C2
		Sirion Biotech Custom design and validation of potent shRNA sequences against SULT1C2

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SULT1C2 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SULT1C2 (see all 3) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): SULT1C2 (NM_001056)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SULT1C2
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SULT1C2

Additional cDNA sequence:

AB008164.1 AF026303.1 AF186251.1 AF186252.1 AF186253.1 AF186254.1 AF186255.1 AF186256.1

AK297086.1 AK298306.1 AK313193.1 BC005353.1 BT006951.1 U66036.1

5 DOTS entries:

DT.114500 DT.100741191 DT.100741193 DT.101980628 DT.40206903

24/99 AceView cDNA sequences (see all 99):

AW466907 AA865827 CD014003 AF186251 AF186253 W88655 BM856476 AW168079

AF186256 CA394967 BC005353 CD014001 AA385029 AF186254 AA360014 AW296125

CD014002 BX116663 AF186252 AF186255 U66036 AL698074 BI760292 AI017244

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SULT1C2 (see all 6) About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	^	3	^	4	^	5a	·	5b	·	5c	^	6a	·	6b	^	7	^	8	^	9a	·	9b
SP1:															-		-
SP2:													-		-
SP3:													-
SP4:													-		-		-		-		-
SP5:													-		-		-		-

ECgene alternative splicing isoforms for SULT1C2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SULT1C2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAACTCTGAG

About this image

SULT1C2 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Human kidney epithelial cell spheroids (Kidney spheroids for...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SULT1C2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SULT1C2

SOURCE GeneReport for Unigene cluster: Hs.436123

UniProtKB/Swiss-Prot: ST1C2_HUMAN, O00338

Tissue specificity: Found in adult stomach, kidney and thyroid gland, and in fetal kidney and liver

SABiosciences Expression via Pathway-Focused PCR Array including SULT1C2:

Drug Metabolism: Phase II Enzymes in human mouse rat

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SULT1C2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for SULT1C2 gene from 4/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	SULT1C2⁶ -- (see all 11)	--	63(a) 55(a) (see all 11)	1 ↔ 1 possible ortholog (see all 11)	GL343220.1(2235687-2245070) GL343287.1(843726-850853)
African clawed frog (Xenopus laevis)	Amphibia	sult1c1-prov²	sulfotransferase family 1A, phenol-preferring, member more	77.66(n)		BC043790.1
zebrafish (Danio rerio)	Actinopterygii	AY196986.1²	--	72.54(n)		AY196986.1
fruit fly (Drosophila melanogaster)	Insecta	CG5428³	sulfotransferase	34(a) (best of 3)		59F6 --

ENSEMBL Gene Tree for SULT1C2 (if available)
TreeFam Gene Tree for SULT1C2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SULT1C2 gene

SULT1C3² SULT4A1² SULT1B1² SULT1C4² SULT1A2² SULT1E1² SULT2B1² SULT1A4²

SULT2A1² SULT6B1² SULT1A1² SULT1A3²

14 SIMAP similar genes for SULT1C2 using alignment to 6 protein entries: ST1C2_HUMAN (see all proteins):

SULT1B1 STP1 SULT1C3 SULT1E1 SULT1A4 ST1A5

SULT1C4 SULT1A3 SULT1A1 SULT1A2 SULT2A1 SULT2B1

SULT6B1 SULT4A1

SULT1C2 for paralogs About GeneDecksing

2 Pseudogenes.org Pseudogenes for SULT1C2
PGOHUM00000247762 PGOHUM00000240839

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs191950052^1,2		--	108903122(+)	`TGTACA/GCTTGG`	2	--	us2k¹		0	--	--	--	--
rs114085671^1,2	F	--	108903210(+)	`GCTTCC/TAGCTA`	2	--	us2k¹		1		WA	118
rs114611604^1,2		--	108903272(+)	`GACTCT/CATGGA`	2	--	us2k¹		1		WA	118
rs17035999^1,2	C,F,H	--	108903370(+)	`GTGTGC/GCAGGC`	2	--	us2k¹		8		NA NS EA WA	678
rs140435600^1,2		--	108903485(+)	`TGTGGG/TGCCCA`	2	--	us2k¹		0	--	--	--	--
rs183818185^1,2		--	108903542(+)	`AGGAGG/TCTTGA`	2	--	us2k¹		0	--	--	--	--
rs72941146^1,2	C,F	--	108903546(+)	`GGCTTG/AAAGTA`	2	--	us2k¹		3		WA	122
rs188313988^1,2		--	108903698(+)	`AAGCAC/TCCAGA`	2	--	us2k¹		0	--	--	--	--
rs191800326^1,2		--	108903718(+)	`ATAAAC/TAACCA`	2	--	us2k¹		0	--	--	--	--
rs117204566^1,2	C,F	--	108903781(+)	`ACTAGT/CAGGGA`	2	--	us2k¹		1		EA	120

HapMap Linkage Disequilibrium report for SULT1C2 (108905095 - 108926371 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for SULT1C2
3 CNVs: 3382 8382 2403
1 Indel: 33342
Human Gene Mutation Database (HGMD): SULT1C2

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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SULT1C2 for disorders           About GeneDecksing

OMIM gene information: 602385    OMIM disorders: --

8 diseases for SULT1C2:    About MalaCards

hearing loss esophagitis thyroiditis adenocarcinoma

hepatitis leukemia neuronitis alcoholism

Human Genome Epidemiology (HuGE) Navigator: SULT1C2 (2 documents)

Export disorders for SULT1C2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for SULT1C2 gene, integrated from 9 sources (see all 33):
(articles sorted by number of sources associating them with SULT1C2)

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Human sulfotransferases SULT1C1 and SULT1C2: cDNA characterization, gene cloning, and chromosomal localization. (PubMed id 10783263)^{1, 2, 3, 9} Freimuth R.R....Weinshilboum R.M. (2000)
Human sulfotransferase SULT1C1: cDNA cloning, tissue-specific expression, and chromosomal localization. (PubMed id 9169148)^{1, 2, 3, 9} Her C.... Weinshilboum R.M. (1997)
Molecular characterization of ST1C1-related human sulfotransferase. (PubMed id 9635888)^{1, 2, 9} Yoshinari K.... Yamazoe Y. (1998)
Crystal structures of human sulfotransferases SULT1B1 and SULT1C1 complexed with the cofactor product adenosine-3'- 5'-diphosphate (PAP). (PubMed id 16804942)^{1, 2, 9} Dombrovski L....Plotnikov A.N. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Molecular cloning, expression, localisation and functional characterisation of a rabbit SULT1C2 sulfotransferase. (PubMed id 10481272)^{1, 2} Hehonah N....McManus M. (1999)
Molecular cloning, expression, and characterization of novel human SULT1C sulfotransferases that catalyze the sulfonation of N-hydroxy-2- acetylaminofluorene. (PubMed id 9852044)^{1, 2} Sakakibara Y.... Liu M.-C. (1998)
Sulfation of iodothyronines by human sulfotransferase 1C1 (SULT1C1)*. (PubMed id 11077054)^{1, 9} Li X....Anderson R.J. (2000)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)¹ Lee O.H....Songyang Z. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 6819	HGNC: 11456	AceView: SULT1C1	Ensembl:ENSG00000198203	euGenes: HUgn6819
ECgene: SULT1C2	H-InvDB: SULT1C2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SULT1C2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SULT1C2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for SULT1C2 gene:
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sulfotransferase family, cytosolic, 1C, member 2

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SULT1C2 Gene

sulfotransferase family, cytosolic, 1C, member 2

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