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SULT1B1 Gene

protein-coding   GIFtS: 62
GCID: GC04M070586

Sulfotransferase Family, Cytosolic, 1B, Member 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sulfotransferase Family, Cytosolic, 1B, Member 11 2     SULT1B22 3
ST1B22 3 5     Sulfotransferase Family Cytosolic 1B Member 12
Sulfotransferase 1B12 3     EC 2.8.2.-3
Sulfotransferase 1B22 3     EC 2.8.28
Thyroid Hormone Sulfotransferase2 3     EC 2.8.2.18
ST1B12 3     EC 2.8.2.48

External Ids:    HGNC: 178451   Entrez Gene: 272842   Ensembl: ENSG000001735977   OMIM: 6084365   UniProtKB: O437043   

Export aliases for SULT1B1 gene to outside databases

Previous GC identifers: GC04M070507 GC04M070641 GC04M070842 GC04M070909 GC04M070910 GC04M070773 GC04M066390


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SULT1B1 Gene:
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and
xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate
specificities. The gene structure (number and length of exons) is similar among family members. However, the
total genomic length of this gene is greater than that of other SULT1 genes. (provided by RefSeq, Jul 2008)

GeneCards Summary for SULT1B1 Gene:
SULT1B1 (sulfotransferase family, cytosolic, 1B, member 1) is a protein-coding gene. Diseases associated with SULT1B1 include endometritis, and thyroiditis. GO annotations related to this gene include sulfotransferase activity and aryl sulfotransferase activity. An important paralog of this gene is SULT1C3.

UniProtKB/Swiss-Prot: ST1B1_HUMAN, O43704
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the
sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases
the water solubility of most compounds, and therefore their renal excretion, but it can also result in
bioactivation to form active metabolites. Sulfates dopamine, small phenols such as 1-naphthol and p-nitrophenol
and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine, reverse triiodothyronine and thyroxine

Gene Wiki entry for SULT1B1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000004.12  NT_016354.20  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SULT1B1 gene promoter:
         c-Fos   USF1   AP-1   Meis-1b   Evi-1   AREB6   POU2F1   POU2F1a   USF-1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSULT1B1 promoter sequence
   Search Chromatin IP Primers for SULT1B1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SULT1B1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q13.3   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q13.3

SULT1B1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SULT1B1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M070586:  view genomic region     (about GC identifiers)

Start:
70,586,880 bp from pter      End:
70,653,679 bp from pter
Size:
66,800 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ST1B1_HUMAN, O43704 (See protein sequence)
Recommended Name: Sulfotransferase family cytosolic 1B member 1  
Size: 296 amino acids; 34899 Da
Subunit: Monomer (By similarity)
2 PDB 3D structures from and Proteopedia for SULT1B1:
2Z5F (3D)        3CKL (3D)    
Secondary accessions: O15497 Q96FI1 Q9UK34

Explore the universe of human proteins at neXtProt for SULT1B1: NX_O43704

Explore proteomics data for SULT1B1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for SULT1B1 (O43704) (see all 7)
     SPFMRKG  PKSGTTW  FTVAQNE  GDWKNYFT 


    See SULT1B1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055280.2  
    ENSEMBL proteins: 
     ENSP00000308770   ENSP00000425464   ENSP00000427536  
    Reactome Protein details: O43704

    SULT1B1 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SULT: Sulfotransferases, cytosolic

    2 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR000863 Sulfotransferase_dom

    Graphical View of Domain Structure for InterPro Entry O43704

    ProtoNet protein and cluster: O43704

    1 Blocks protein domain: IPB000863 Sulfotransferase

    UniProtKB/Swiss-Prot: ST1B1_HUMAN, O43704
    Similarity: Belongs to the sulfotransferase 1 family


    SULT1B1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ST1B1_HUMAN, O43704
    Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the
    sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases
    the water solubility of most compounds, and therefore their renal excretion, but it can also result in
    bioactivation to form active metabolites. Sulfates dopamine, small phenols such as 1-naphthol and p-nitrophenol
    and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine, reverse triiodothyronine and thyroxine

         Enzyme Numbers (IUBMB): EC 2.8.2.-1 EC 2.8.2.42 EC 2.8.22 EC 2.8.2.12

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004062aryl sulfotransferase activity IEA--
    GO:0008146sulfotransferase activity IDA--
         
    SULT1B1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SULT1B1:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SULT1B1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SULT1B1
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    miRNA
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    miRTarBase miRNAs that target SULT1B1:
    hsa-mir-124-3p (MIRT022947), hsa-mir-26b-5p (MIRT029950)

    Block miRNA regulation of human, mouse, rat SULT1B1 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate SULT1B1:
    hsa-miR-340
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: SULT1B1 (NM_014465)
    Sino Biological Human cDNA Clone for SULT1B1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SULT1B1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SULT1B1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ST1B1_HUMAN, O43704: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus2
    plasma membrane2
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--

    SULT1B1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SULT1B1 About    
    See pathways by source

    SuperPathContained pathways About
    1Biological oxidations
    Biological oxidations0.56
    metapathway biotransformation0.42
    Phase II conjugation0.56
    Cytosolic sulfonation of small molecules0.00
    2Metabolism
    Metabolism0.38
    3Sulfation Biotransformation Reaction
    Sulfation Biotransformation Reaction

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for SULT1B1
        Sulfation Biotransformation Reaction
    metapathway biotransformation


    1 Reactome Pathway for SULT1B1
        Cytosolic sulfonation of small molecules



    SULT1B1 for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Array including SULT1B1: 
              Drug Metabolism: Phase II Enzymes in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for SULT1B1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for SULT1B1 (ENSP000003087704) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    POT1ENSP000003502494STRING: ENSP00000350249
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006576cellular biogenic amine metabolic process TAS9443824
    GO:0006805xenobiotic metabolic process TAS--
    GO:0008202steroid metabolic process IEA--
    GO:0009812flavonoid metabolic process IDA--
    GO:0018958phenol-containing compound metabolic process IDA9463486

    SULT1B1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SULT1B1 (ST1B1)

    1 DrugBank Compound for SULT1B1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Adenosine-3'-5'-Diphosphate-- --target----

    3 Novoseek inferred chemical compound relationships for SULT1B1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    p-nitrophenol 79.2 1 16413005 (1)
    phenol 63.3 2 9644246 (1)
    estrogen 14.7 2 9644246 (1)



    SULT1B1 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SULT1B1 gene: 
    NM_014465.3  

    Unigene Cluster for SULT1B1:

    Sulfotransferase family, cytosolic, 1B, member 1
    Hs.129742  [show with all ESTs]
    Unigene Representative Sequence: BC010895
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000310613(uc003hen.3) ENST00000510821 ENST00000512870
    miRNA
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    1 qRT-PCR Assays for microRNA that regulate SULT1B1:
    hsa-miR-340
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    Inhib. RNA
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SULT1B1
      QuantiTect SYBR Green Assays in human, mouse, rat SULT1B1
      QuantiFast Probe-based Assays in human, mouse, rat SULT1B1

    Additional mRNA sequence: 

    BC010895.1 D89479.1 U95726.1 

    1 DOTS entry:

    DT.402685 

    8 AceView cDNA sequences:

    BE463423 BC010895 U95726 NM_014465 BX281432 D89479 BG461453 BF241490 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SULT1B1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTAAAAACTG
    SULT1B1 Expression
    About this image


    SULT1B1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Adipose (Muscoskeletal System)
             HyStem+BMP4-induced SM30 cells
     
     NULL (Uncategorized)
             CD31, CD144 positive cells
     
     Endothelium (Cardiovascular System)
             Human umbilical vein endothelial cells (HUVEC)
     
     Umbilical Cord (Extraembryonic Tissues)
             Wharton's jelly-derived stem cells
     
     Liver (Hepatobiliary System)
             Perivenous Hepatocytes Liver Lobule
    SULT1B1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SULT1B1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.129742

    UniProtKB/Swiss-Prot: ST1B1_HUMAN, O43704
    Tissue specificity: Highly expressed in the liver, peripheral blood leukocytes, colon (mucosal lining), small
    intestine (jejunum) and spleen. A lesser expression was observed in the lung, placenta and thymus

        Pathway & Disease-focused RT2 Profiler PCR Array including SULT1B1: 
              Drug Metabolism: Phase II Enzymes in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SULT1B1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sult1b11 , 5 sulfotransferase family 1B, member 11, 5 80.29(n)1
    72.3(a)1
      5 (43.56 cM)5
    563621  NM_019878.41  NP_063931.11 
     875133395 
    chicken
    (Gallus gallus)
    Aves SULT1B11 sulfotransferase family, cytosolic, 1B, member 1 62.28(n)
    61.25(a)
      395227  NM_204545.1  NP_989876.1 
    lizard
    (Anolis carolinensis)
    Reptilia SULT1B16
    sulfotransferase family, cytosolic, 1B, member 1
    53(a)
    1 ↔ 1
    6(58696591-58717281)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.123172 Transcribed sequence with weak similarity to protein more 72.95(n)    BX706612.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sult1st22 sulfotransferase family 1, cytosolic sulfotransferase more 74.33(n)   368269  AY181065.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG54283
    St11
    sulfotransferase3
    Sulfotransferase 11
    33(a)
    (best of 3)3
    44.89(n)1
    32.26(a)1
      59F63
    377421  NM_137971.31  NP_611815.31 
    worm
    (Caenorhabditis elegans)
    Secernentea Y113G7A.113
    ssu-11
    ssu-11 32(a)3
    51.42(n)1
    35.9(a)1
      V(20120519-20125245)3
    1909591  NM_075479.11  NP_507880.11 


    ENSEMBL Gene Tree for SULT1B1 (if available)
    TreeFam Gene Tree for SULT1B1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SULT1B1 gene
    SULT1C32  SULT4A12  SULT1A22  SULT1C42  SULT1C22  SULT1E12  SULT2B12  SULT1A42  
    SULT2A12  SULT6B12  SULT1A12  SULT1A32  
    13 SIMAP similar genes for SULT1B1 using alignment to 3 protein entries:     ST1B1_HUMAN (see all proteins):
    SULT1C2    SULT1A3    SULT1E1    ST1A5    SULT1A4    SULT1A2
    SULT1C3    SULT1C4    SULT1A1    SULT2A1    SULT2B1    SULT4A1
    SULT6B1

    SULT1B1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SULT1B1
    PGOHUM00000250718


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SULT1B1 (see all 787)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1494639841,2
    --70592227(+) TAGGTA/TTGATA 1 -- ds50010--------
    rs41494191,2
    C,F,H--70592242(-) GAAATC/ATTTTT 1 -- ds500122Minor allele frequency- A:0.26NS EA NA 2300
    rs1812120051,2
    --70592327(+) ACTCAA/GAGAAC 1 -- ds50010--------
    rs41494181,2
    C,F,H--70592360(-) TGTGTT/GCCACT 1 -- ds500112Minor allele frequency- G:0.05NS EA NA 1732
    rs1856436321,2
    --70592418(+) GAAATA/GTAGTC 1 -- ds50010--------
    rs1438460101,2
    C--70592429(+) TCATTA/GTGAAA 1 -- ds50010--------
    rs1156494161,2
    C,F--70592528(+) TCTTAT/CCAGTA 1 -- ds50011Minor allele frequency- C:0.01WA 118
    rs1399757031,2
    --70592548(+) AAAAAC/GGCAGG 1 -- ds50010--------
    rs1895228881,2
    --70592594(+) AAGTTA/GACAAT 1 -- ds50010--------
    rs115697281,2
    C,F,H--70592604(-) GCTAAA/TGTTCA 1 -- ds50018Minor allele frequency- T:0.10NS EA NA WA 900

    HapMap Linkage Disequilibrium report for SULT1B1 (70586880 - 70653679 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SULT1B1:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv5626n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SULT1B1
    DNA2.0 Custom Variant and Variant Library Synthesis for SULT1B1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608436    OMIM disorders: --

    7 diseases for SULT1B1:    
    About MalaCards
    endometritis    thyroiditis    tonsillitis    malaria
    cerebritis    hepatitis    endotheliitis


    SULT1B1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SULT1B1
    Human Genome Epidemiology (HuGE) Navigator: SULT1B1 (3 documents)

    Export disorders for SULT1B1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SULT1B1 gene, integrated from 10 sources (see all 27):
    (articles sorted by number of sources associating them with SULT1B1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of rat ST1B1 and human ST1B2 cDNAs, encoding thyroid hormone sulfotransferases. (PubMed id 9443824)1, 2, 3, 9 Fujita K.... Yamazoe Y. (J. Biochem. 1997)
    2. Structure and localization of the human SULT1B1 gene: neighborhood to SULT1E1 and a SULT1D pseudogene. (PubMed id 11688987)1, 3, 9 Meinl W. and Glatt H. (Biochem. Biophys. Res. Commun. 2001)
    3. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1, 4 Saito A....Kamatani N. (J. Hum. Genet. 2009)
    4. Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. (PubMed id 19898482)1, 4 Ross C.J....Hayden M.R. (Nat. Genet. 2009)
    5. Crystal structures of human sulfotransferases SULT1B1 and SULT1C1 complexed with the cofactor product adenosine-3'- 5'-diphosphate (PAP). (PubMed id 16804942)1, 2 Dombrovski L.... Plotnikov A.N. (Proteins 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Expression and characterization of a novel thyroid hormone-sulfating form of cytosolic sulfotransferase from human liver. (PubMed id 9463486)1, 2 Wang J.... Falany C.N. (Mol. Pharmacol. 1998)
    8. Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (amp 2011)
    9. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    10. Structural and chemical profiling of the human cytosolic sulfotransferases. (PubMed id 17425406)1 Allali-Hassani A.... Arrowsmith C.H. (PLoS Biol. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 27284 HGNC: 17845 AceView: SULT1B1 Ensembl:ENSG00000173597 euGenes: HUgn27284
    ECgene: SULT1B1 H-InvDB: SULT1B1

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SULT1B1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SULT1B1 gene:
    Search GeneIP for patents involving SULT1B1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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