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SULT1A2 Gene

protein-coding   GIFtS: 65
GCID: GC16M028603

Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring,...


(Previous symbol: STP2)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 21 2     P-PST2
STP21 2 3 5     TSPST22
Aryl Sulfotransferase 22 3     Arylamine Sulfotransferase2
Phenol Sulfotransferase 22 3     Phenol-Preferring Phenol Sulfotransferase22
Phenol-Sulfating Phenol Sulfotransferase 22 3     Phenolic-Metabolizing (P) Form Of PST2
ST1A22 3     Sulfotransferase 1A22
P-PST 22 3     Thermostable Phenol Sulfotransferase2
EC 2.8.2.13 8     EC 2.8.28
HAST42     

External Ids:    HGNC: 114541   Entrez Gene: 67992   Ensembl: ENSG000001971657   OMIM: 6012925   UniProtKB: P502263   

Export aliases for SULT1A2 gene to outside databases

Previous GC identifers: GC16M028947 GC16P028687 GC16P028432 GC16P028496 GC16P028470 GC16M028510 GC16M026628


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SULT1A2 Gene:
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and
xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate
specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes
one of two phenol sulfotransferases with thermostable enzyme activity. Two alternatively spliced variants that
encode the same protein have been described. (provided by RefSeq, Jul 2008)

GeneCards Summary for SULT1A2 Gene:
SULT1A2 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2) is a protein-coding gene. GO annotations related to this gene include sulfotransferase activity and flavonol 3-sulfotransferase activity. An important paralog of this gene is SULT1C3.

UniProtKB/Swiss-Prot: ST1A2_HUMAN, P50226
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the
sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the
sulfonation and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to
DNA binding products and could so participate as modulating factor of cancer risk

Gene Wiki entry for SULT1A2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NT_187260.1  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SULT1A2 gene promoter:
         STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSULT1A2 promoter sequence
   Search Chromatin IP Primers for SULT1A2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SULT1A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.1   Ensembl cytogenetic band:  16p11.2   HGNC cytogenetic band: 16p12.1

SULT1A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SULT1A2 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M028603:  view genomic region     (about GC identifiers)

Start:
28,603,264 bp from pter      End:
28,608,430 bp from pter
Size:
5,167 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ST1A2_HUMAN, P50226 (See protein sequence)
Recommended Name: Sulfotransferase 1A2  
Size: 295 amino acids; 34310 Da
Subunit: Homodimer (By similarity)
1 PDB 3D structure from and Proteopedia for SULT1A2:
1Z29 (3D)    
Secondary accessions: A9QY25 P78393 Q14CJ7

Explore the universe of human proteins at neXtProt for SULT1A2: NX_P50226

Explore proteomics data for SULT1A2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys106
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for SULT1A2 (P50226) (see all 13)
     LYLFYED  FTVAQNE  VSYYHFY  SPFMRKG 


    See SULT1A2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001045.1  NP_803564.1  

    ENSEMBL proteins: 
     ENSP00000433075   ENSP00000435271   ENSP00000338742   ENSP00000435358   ENSP00000378992  
    Reactome Protein details: P50226

    SULT1A2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SULT: Sulfotransferases, cytosolic

    2 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR000863 Sulfotransferase_dom

    Graphical View of Domain Structure for InterPro Entry P50226

    ProtoNet protein and cluster: P50226

    1 Blocks protein domain: IPB000863 Sulfotransferase

    UniProtKB/Swiss-Prot: ST1A2_HUMAN, P50226
    Similarity: Belongs to the sulfotransferase 1 family


    Find genes that share domains with SULT1A2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ST1A2_HUMAN, P50226
    Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the
    sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the
    sulfonation and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to
    DNA binding products and could so participate as modulating factor of cancer risk
    Catalytic activity: 3'-phosphoadenylyl sulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate

         Genatlas biochemistry entry for SULT1A2:
    aryl (phenol) sulfotransferase 2,phenol preferring,cytosolic

         Enzyme Numbers (IUBMB): EC 2.8.2.11 2 EC 2.8.22

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004062aryl sulfotransferase activity IDA--
    GO:0008146sulfotransferase activity TAS9119390
    GO:0047894flavonol 3-sulfotransferase activity IDA--
         
    Find genes that share ontologies with SULT1A2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SULT1A2:
     Synthetic lethal with Ras 

    Animal Models:
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ST1A2_HUMAN, P50226: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    nucleus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--

    Find genes that share ontologies with SULT1A2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SULT1A2 About   (see all 7)  
    See pathways by source

    SuperPathContained pathways About
    1Biological oxidations
    Biological oxidations0.56
    metapathway biotransformation0.42
    Phase II conjugation0.56
    Cytosolic sulfonation of small molecules0.00
    2Chemical carcinogenesis
    Chemical carcinogenesis0.71
    Arylamine metabolism0.00
    3tryptophan utilization II
    tryptophan utilization II0.71
    serotonin degradation0.00
    tryptophan utilization I0.71
    melatonin degradation I0.00
    superpathway of melatonin degradation0.00
    4Metabolism
    Metabolism0.38
    5thyroid hormone metabolism II (via conjugation and/or degradation)
    thyroid hormone metabolism II (via conjugation and/or degradation)


    Find genes that share SuperPaths with SULT1A2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for SULT1A2
        2-Naphthylamine and 2-Nitronaphtalene metabolism

    Selected BioSystems Pathways for SULT1A2 (see all 9)
        Sulfation Biotransformation Reaction
    Arylamine metabolism
    serotonin degradation
    melatonin degradation I
    thyroid hormone metabolism II (via conjugation and/or degradation)


    1 Reactome Pathway for SULT1A2
        Cytosolic sulfonation of small molecules


    1 Kegg Pathway  (Kegg details for SULT1A2):
        Chemical carcinogenesis

        Pathway & Disease-focused RT2 Profiler PCR Array including SULT1A2: 
              Drug Metabolism: Phase II Enzymes in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for SULT1A2

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for SULT1A2 (ENSP000003387424) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BPNT1ENSP000003188524STRING: ENSP00000318852
    PAPSS1ENSP000002651744STRING: ENSP00000265174
    PAPSS2ENSP000004061574STRING: ENSP00000406157
    MYCENSP000003672074STRING: ENSP00000367207
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006584catecholamine metabolic process IEA--
    GO:0006805xenobiotic metabolic process TAS--
    GO:0008202steroid metabolic process IEA--
    GO:0009309amine biosynthetic process TAS9119390
    GO:0018958phenol-containing compound metabolic process IDA--

    Find genes that share ontologies with SULT1A2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SULT1A2 (ST1A2)

    3 HMDB Compounds for SULT1A2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine 3',5'-diphosphate3,5-Diphosphoadenosine (see all 10)1053-73-2--
    Phenolacide carbolique (see all 51)108-95-2--
    Phosphoadenosine phosphosulfate3'-Phospho-5'-adenylyl sulfate (see all 9)482-67-7--

    4 Novoseek inferred chemical compound relationships for SULT1A2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    p-nitrophenol 73.2 2 8697101 (1), 12464797 (1)
    phenol 72.4 9 8912648 (2), 9723178 (2), 8697101 (1), 9566748 (1) (see all 6)
    3-phosphoadenosine 5'-phosphosulfate 67.8 2 9566739 (2)
    epoxide 45.2 1 12419832 (1)

    1 PharmGKB related drug/compound annotation for SULT1A2 gene    About this table
    Drug/compound PharmGKB Annotation
    conjugated estrogensCA  



    Find genes that share compounds with SULT1A2           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SULT1A2 gene (2 alternative transcripts): 
    NM_001054.3  NM_177528.2  

    Unigene Cluster for SULT1A2:

    Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
    Hs.546304  [show with all ESTs]
    Unigene Representative Sequence: BC052280
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000534108 ENST00000533150 ENST00000335715(uc002dqh.2) ENST00000526384
    ENST00000395630(uc002dqg.2)
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    Additional mRNA sequence: 

    BC052280.1 BC113727.1 BC113729.1 U28169.1 U28170.1 X78282.1 

    15 DOTS entries:

    DT.87016795  DT.100774569  DT.95099157  DT.40105824  DT.91750591  DT.40190817  DT.87002066  DT.100650699 
    DT.100671058  DT.100761322  DT.91750594  DT.92030572  DT.92054627  DT.95101094  DT.97862974 

    Selected AceView cDNA sequences (see all 203):

    NM_177536 NM_177528 CB146610 BI832457 BC000923 CR606821 BF109060 CB148809 
    BX283396 CR608214 BX280592 CR618607 NM_177529 BI824234 CR601418 AI273979 
    T87887 NM_177530 BG527484 AW474726 NM_001055 NM_177534 BI523841 BU594653 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SULT1A2    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                                                          
    SP2:                          -                                                               
    SP3:                          -     -     -     -     -     -     -     -                     
    SP4:                                                  -     -     -     -     -               
    SP5:                                                                                          


    ECgene alternative splicing isoforms for SULT1A2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SULT1A2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTGGGGACT
    SULT1A2 Expression
    About this image

    SULT1A2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SULT1A2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.546304
        Pathway & Disease-focused RT2 Profiler PCR Array including SULT1A2: 
              Drug Metabolism: Phase II Enzymes in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SULT1A2 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    59(a)
    59(a)
    many ↔ many
    many ↔ many
    GL343287.1(1045659-1052531)
    GL343287.1(1028874-1041016)
            Species with no ortholog for SULT1A2

    ENSEMBL Gene Tree for SULT1A2 (if available)
    TreeFam Gene Tree for SULT1A2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SULT1A2 gene
    SULT1C32  SULT4A12  SULT1B12  SULT1C42  SULT1C22  SULT1E12  SULT2B12  SULT1A42  
    SULT2A12  SULT6B12  SULT1A12  SULT1A32  
    14 SIMAP similar genes for SULT1A2 using alignment to 4 protein entries:     ST1A2_HUMAN (see all proteins):
    STP1    SULT1A4    SULT1A3    ST1A5    SULT1A1    SULT1B1
    SULT1E1    SULT1C2    SULT1C4    SULT2A1    SULT1C3    SULT2B1
    SULT4A1    SULT6B1

    Find genes that share paralogs with SULT1A2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SULT1A2 (see all 294)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs454723921,2,,4
    C,F--28603643(-) GACCAA/GCTACA 4 N S mis13Minor allele frequency- G:0.01NA 4794
    rs10594911,2,,4
    C,F,A,H--28603655(-) GAAGAA/CCCCTA 4 N T mis1 ese315Minor allele frequency- C:0.31MN NA CSA EU 6719
    rs1415691141,2
    C--28603675(+) TTGAAC/TGACGT 4 S syn10--------
    rs2015468831,2
    --28603680(+) CGACGC/TGTGCT 4 T A mis10--------
    rs115697631,2
    C,F,H--28603683(-) TTGAGC/GACACG 4 H D mis1 ese36Minor allele frequency- G:0.01NS EA NA 5208
    rs10420411,2
    C--28603686(-) TGGTTG/CAGCAC 4 /Q /E mis13Minor allele frequency- C:0.00NA 244
    rs1381476091,2
    C--28603710(+) CTCCTA/CTGGCA 4 E * stg10--------
    rs1415818531,2
    C,F--28603721(+) GGGAGC/TGCCCC 4 H R mis11Minor allele frequency- T:0.01EU 787
    rs2001283341,2
    C--28603722(+) GGAGCA/GCCCCA 4 R C mis10--------
    rs1830309821,2
    C--28603725(+) GCGCCC/TCACAA 4 R G mis10--------

    HapMap Linkage Disequilibrium report for SULT1A2 (28603264 - 28608430 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SULT1A2 (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2667967CNV Deletion23128226
    esv2714170CNV Deletion23290073
    nsv436734CNV Insertion17901297
    nsv1775CNV Insertion18451855
    nsv509608CNV Insertion20534489
    nsv905689CNV Loss21882294
    nsv905694CNV Loss21882294
    dgv12n14CNV Loss18776910
    nsv905690CNV Gain21882294
    dgv2664n71CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 601292    OMIM disorders: --


    Find genes that share disorders with SULT1A2           About GenesLikeMe

    2 Novoseek inferred disease relationships for SULT1A2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    colorectal cancer 8.74 1 12419832 (1)
    breast cancer 4.36 2 15754005 (1), 18798070 (1)

    Genetic Association Database (GAD): SULT1A2
    Human Genome Epidemiology (HuGE) Navigator: SULT1A2 (18 documents)

    Export disorders for SULT1A2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SULT1A2 gene, integrated from 10 sources (see all 58):
    (articles sorted by number of sources associating them with SULT1A2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human phenol sulfotransferase STP2 gene: molecular cloning, structural characterization, and chromosomal localization. (PubMed id 8661000)1, 2, 3, 9 Her C.... Weinshilboum R.M. (Genomics 1996)
    2. Genomic organization and DNA sequences of two human phenol sulfotransferase genes (STP1 and STP2) on the short arm of chromosome 16. (PubMed id 8912648)1, 2, 3, 9 Dooley T.P. and Huang Z. (Biochem. Biophys. Res. Commun. 1996)
    3. Cloning, structural organization, and chromosomal mapping of the human phenol sulfotransferase STP2 gene. (PubMed id 9119390)1, 2, 9 Gaedigk A.... Grant D.M. (Genomics 1997)
    4. cDNA cloning and expression of a new form of human aryl sulfotransferase. (PubMed id 8697101)1, 2, 9 Zhu X.... McManus M.E. (Int. J. Biochem. Cell Biol. 1996)
    5. A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. (PubMed id 12419832)1, 4, 9 Sachse C....Wolf C.R. (Carcinogenesis 2002)
    6. Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2. (PubMed id 20417180)1, 2 Lu J.... Chang W. (Biochem. Biophys. Res. Commun. 2010)
    7. Genetic susceptibility to distinct bladder cancer subphenotypes. (PubMed id 19692168)1, 4 Guey L.T....Malats N. (Eur. Urol. 2010)
    8. Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer. (PubMed id 20214802)1, 4 Li J....Hall P. (Breast Cancer Res. 2010)
    9. Common variants at five new loci associated with early-onset inflammatory bowel disease. (PubMed id 19915574)1, 4 Imielinski M....Hakonarson H. (Nat. Genet. 2009)
    10. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1, 4 Saito A....Kamatani N. (J. Hum. Genet. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6799 HGNC: 11454 AceView: SULT1A2andSULT1A1 Ensembl:ENSG00000197165 euGenes: HUgn6799
    ECgene: SULT1A2 Kegg: 6799 H-InvDB: SULT1A2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SULT1A2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SULT1A2 gene:
    Search GeneIP for patents involving SULT1A2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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