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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SULT1A2 Gene

protein-coding   GIFtS: 64
GCID: GC16M028603

sulfotransferase family, cytosolic, 1A, phenol-preferring,...


(Previous symbol: STP2)
 Explore 8 diseases affiliated with
SULT1A2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SULT1A2    

Aliases
for SULT1A2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 21 2     P-PST2
STP21 2 3 5     TSPST22
HAST41 2     Arylamine Sulfotransferase2
Aryl Sulfotransferase 22 3     Phenol-Preferring Phenol Sulfotransferase22
Phenol Sulfotransferase 22 3     Phenolic-Metabolizing (P) Form Of PST2
Phenol-Sulfating Phenol Sulfotransferase 22 3     Sulfotransferase 1A22
ST1A22 3     Thermostable Phenol Sulfotransferase2
P-PST 22 3     EC 2.8.28
EC 2.8.2.13 8     

External Ids:    HGNC: 114541   Entrez Gene: 67992   Ensembl: ENSG000001971657   OMIM: 6012925   UniProtKB: P502263   

Export aliases for SULT1A2 gene to outside databases

Previous GC identifers: GC16M028947 GC16P028687 GC16P028432 GC16P028496 GC16P028470 GC16M028510 GC16M026628


Summaries
for SULT1A2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SULT1A2:
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic
compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene
structure (number and length of exons) is similar among family members. This gene encodes one of two phenol
sulfotransferases with thermostable enzyme activity. Two alternatively spliced variants that encode the same protein
have been described. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ST1A2_HUMAN, P50226
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the
sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the sulfonation
and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding
products and could so participate as modulating factor of cancer risk

Gene Wiki entry for SULT1A2


Genomic Views
for SULT1A2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SULT1A2 gene promoter:
         STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SULT1A2 promoter sequence
   Search SABiosciences Chromatin IP Primers for SULT1A2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SULT1A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.1   Ensembl cytogenetic band:  16p11.2   HGNC cytogenetic band: 16p12.1

SULT1A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SULT1A2 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M028603:  view genomic region     (about GC identifiers)

Start:
 28,603,264 bp from pter      End:
 28,608,430 bp from pter
Size:
 5,167 bases      Orientation:
 minus strand

Proteins
for SULT1A2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ST1A2_HUMAN, P50226 (See protein sequence)
Recommended Name: Sulfotransferase 1A2  
Size: 295 amino acids; 34310 Da
Subunit: Homodimer (By similarity)
Subcellular location: Cytoplasm
1 PDB 3D structure from and Proteopedia for SULT1A2:
1Z29 (3D)    
Secondary accessions: A9QY25 P78393 Q14CJ7

Explore the universe of human proteins at neXtProt for SULT1A2: NX_P50226

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P50226

    • 4/13 DME Specific Peptides for SULT1A2 (P50226) (see all 13)
     LYLFYED  FTVAQNE  VSYYHFY  SPFMRKG 

    SULT1A2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001045.1  NP_803564.1  

    ENSEMBL proteins: 
     ENSP00000433075   ENSP00000435271   ENSP00000338742   ENSP00000435358   ENSP00000378992  
    Reactome Protein details: P50226
    Human Recombinant Protein Products: 
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    ProSpec Recombinant Protein for SULT1A2
    Uscn Proteins for SULT1A2

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--


    SULT1A2 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for SULT1A2

    Protein Domains /
    Families
    for SULT1A2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SULT1A2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR000863 Sulfotransferase_dom

    Graphical View of Domain Structure for InterPro Entry P50226

    ProtoNet protein and cluster: P50226

    1 Blocks protein family: IPB000863 Sulfotransferase

    UniProtKB/Swiss-Prot: ST1A2_HUMAN, P50226
    Similarity: Belongs to the sulfotransferase 1 family


    Function
    for SULT1A2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ST1A2_HUMAN, P50226
    Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the
    sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the sulfonation
    and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding
    products and could so participate as modulating factor of cancer risk
    Catalytic activity: 3'-phosphoadenylyl sulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate

         Genatlas biochemistry entry for SULT1A2:
    aryl (phenol) sulfotransferase 2,phenol preferring,cytosolic

    Enzyme Numbers (IUBMB): EC 2.8.2.11 2 EC 2.8.22

    miRNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004062aryl sulfotransferase activity IDA--
    GO:0008146sulfotransferase activity TAS9119390
    GO:0047894flavonol 3-sulfotransferase activity IDA--


    SULT1A2 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SULT1A2:
     Synthetic lethal with Ras 


    Pathways & Interactions
    for SULT1A2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cytosolic sulfonation of small molecules
    		Cytosolic sulfonation of small molecules1.00
    		Sulfur metabolism0.44
    		Sulfation Biotransformation Reaction0.67
    2Biological oxidations
    		Biological oxidations1.00
    		metapathway biotransformation0.41
    		Phase II conjugation0.52
    32-Naphthylamine and 2-Nitronaphtalene metabolism
    		2-Naphthylamine and 2-Nitronaphtalene metabolism1.00
    		2-Naphthylamine and 2-Nitronaphtalene metabolism0.95
    4superpathway of melatonin degradation
    		superpathway of melatonin degradation1.00
    		melatonin degradation I0.85
    5serotonin degradation
    		serotonin degradation1.00
    		dopamine degradation0.58

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for SULT1A2
        2-Naphthylamine and 2-Nitronaphtalene metabolism


    1 GeneGo (Thomson Reuters) Pathway for SULT1A2
        2-Naphthylamine and 2-Nitronaphtalene metabolism

    5/8 BioSystems Pathways for SULT1A2 (see all 8) 
        Sulfation Biotransformation Reaction
    serotonin degradation
    thyroid hormone metabolism II (via conjugation and/or degradation)
    melatonin degradation I
    Arylamine metabolism

    4        Reactome Pathways for SULT1A2
        Metabolism
    Biological oxidations
    Cytosolic sulfonation of small molecules
    Phase II conjugation


    1         Kegg Pathway  (Kegg details for SULT1A2):
        Sulfur metabolism


    SULT1A2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SULT1A2

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for SULT1A2 (ENSP000003387424) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PAPSS1ENSP000002651744STRING: ENSP00000265174
    PAPSS2ENSP000004061574STRING: ENSP00000406157
    BPNT1ENSP000003188524STRING: ENSP00000318852
    MYCENSP000003672074STRING: ENSP00000367207
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006584catecholamine metabolic process IEA--
    GO:0006805xenobiotic metabolic process TAS--
    GO:0008202steroid metabolic process IEA--
    GO:0009309amine biosynthetic process TAS9119390
    GO:0018958phenol-containing compound metabolic process IDA--


    SULT1A2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SULT1A2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SULT1A2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for SULT1A2

    3 HMDB Compounds for SULT1A2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine 3',5'-diphosphate3,5-Diphosphoadenosine (see all 10)1053-73-2--
    Phenolacide carbolique (see all 51)108-95-2--
    Phosphoadenosine phosphosulfate3'-Phospho-5'-adenylyl sulfate (see all 9)482-67-7--
    4 Novoseek chemical compound relationships for SULT1A2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    p-nitrophenol 73.2 2 8697101 (1), 12464797 (1)
    phenol 72.4 9 8912648 (2), 9723178 (2), 8697101 (1), 9566748 (1) (see all 6)
    3-phosphoadenosine 5'-phosphosulfate 67.8 2 9566739 (2)
    epoxide 45.2 1 12419832 (1)

    1 PharmGKB related drug/compound annotation for SULT1A2 gene
    Drug/compound PharmGKB Annotation
    conjugated estrogensCA  
    About this table

    Search CenterWatch for drugs/clinical trials and news about SULT1A2 / ST1A2 

    Transcripts
    for SULT1A2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SULT1A2 gene (2 alternative transcripts): 
    NM_001054.3  NM_177528.2  

    Unigene Cluster for SULT1A2:

    Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
    Hs.546304  [show with all ESTs]
    Unigene Representative Sequence: BC052280
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000534108 ENST00000533150 ENST00000335715(uc002dqh.2) ENST00000526384
    ENST00000395630(uc002dqg.2)

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    Additional cDNA sequence: 

    BC052280.1 BC113727.1 BC113729.1 U28169.1 U28170.1 X78282.1 

    15 DOTS entries:

    DT.87016795  DT.100774569  DT.95099157  DT.40105824  DT.91750591  DT.40190817  DT.87002066  DT.100650699 
    DT.100671058  DT.100761322  DT.91750594  DT.92030572  DT.92054627  DT.95101094  DT.97862974 

    24/203 AceView cDNA sequences (see all 203):

    BG527484 NM_177529 AW474726 BX280592 CB148809 BF109060 NM_177530 NM_001055 
    BC000923 BX283396 BI824234 NM_177528 AI273979 BI832457 CR601418 NM_177536 
    T87887 BI523841 CR618607 CR608214 NM_177534 CB146610 CR606821 AB062428 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SULT1A2    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                                                          
    SP2:                          -                                                               
    SP3:                          -     -     -     -     -     -     -     -                     
    SP4:                                                  -     -     -     -     -               
    SP5:                                                                                          


    ECgene alternative splicing isoforms for SULT1A2

    Expression
    for SULT1A2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SULT1A2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCTGGGGACT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SULT1A2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Posterior foregut-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See SULT1A2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SULT1A2

    SOURCE GeneReport for Unigene cluster: Hs.546304
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              Drug Metabolism: Phase II Enzymes in human mouse rat

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    In Situ
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    Orthologs
    for SULT1A2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for SULT1A2 gene from 3/10 species (see all 10)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    		 --
    		 59(a)
    57(a)
    		 many ↔ many
    many ↔ many
    		 GL343287.1(1045659-1052531)
    GL343287.1(1030047-1040195)
    zebrafish
    (Danio rerio)    		 Actinopterygii sult1st26
    si:ch211-196g2.66
    (see all 6)    		 si:ch211-196g2.6
    (see all 6)    		 48(a)
    48(a)
    (see all 6)    		 many ↔ many
    many ↔ many
    (see all 6)    		 8(48667606-48678955)
    8(48600924-48611096)
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG54283 sulfotransferase 33(a)
    (best of 2)    		   59F6   --


    ENSEMBL Gene Tree for SULT1A2 (if available)
    TreeFam Gene Tree for SULT1A2 (if available) 

    Paralogs
    for SULT1A2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SULT1A2 gene
    SULT1C32  SULT4A12  SULT1B12  SULT1C42  SULT1C22  SULT2B12  SULT1E12  SULT1A42  
    SULT2A12  SULT6B12  SULT1A12  SULT1A32  
    14 SIMAP similar genes for SULT1A2 using alignment to 4 protein entries:     ST1A2_HUMAN (see all proteins):
    STP1    SULT1A4    SULT1A3    ST1A5    SULT1A1    SULT1B1
    SULT1E1    SULT1C2    SULT1C4    SULT2A1    SULT1C3    SULT2B1
    SULT4A1    SULT6B1

    SULT1A2 for paralogs           About GeneDecksing



    Genomic Variants
    for SULT1A2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/262 NCBI SNPs in SULT1A2 are shown (see all 262)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 16 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1477523511,2
    		C,--28602839(+) GTCTAC/GGCTGG 3 -- int1 ds50010--------
    rs2010414041,2
    		--28603031(+) GATGCC/TGCCTG 3 -- ds5001 ut310--------
    rs1812315391,2
    		C,--28603046(+) ACTCGC/TCATCC 3 -- ds5001 ut310--------
    rs1866979571,2
    		C,--28603057(+) CCCAAC/TGACAC 3 -- ds5001 ut310--------
    rs49872231,2
    		C,F,--28603082(-) AGCAYG/ATCCTC 3 -- ut31 ds50015Minor allele frequency- A:0.01MN 408
    rs49872221,2
    		C,F,H,--28603083(-) CAGCAC/TRTCCT 3 -- ds5001 ut3116Minor allele frequency- T:0.01MN NS EA NA WA 1650
    rs20770311,2
    		C,F,A,H,--28603168(-) TCCTCA/TACTTG 3 -- ds5001 int114Minor allele frequency- T:0.16NS EA NA CSA WA 2491
    rs1130049521,2
    		F,--28603184(+) AGCGGG/AGAGGT 3 -- ds5001 int13Minor allele frequency- A:0.10CSA WA 122
    rs1457906111,2
    		--28603263(+) TCTGCA/GTTGAA 3 -- ds5001 int10--------
    rs2004090611,2
    		--28603315(+) ATTCGC/TACACT 3 -- ut31 int10--------

    HapMap Linkage Disequilibrium report for SULT1A2 (28603264 - 28608430 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for SULT1A2
         3 CNVs: 30771 4938 3999

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    Disorders / Diseases
    for SULT1A2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SULT1A2 for disorders           About GeneDecksing

    OMIM gene information: 601292    OMIM disorders: --

    8 diseases for SULT1A2:    About MalaCards
    breast cancer susceptibility    inflammatory bowel disease    breast cancer    colorectal cancer
    thyroiditis    hepatitis    neuronitis    alcoholism

    2 Novoseek disease relationships for SULT1A2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    colorectal cancer 8.74 1 12419832 (1)
    breast cancer 4.36 2 15754005 (1), 18798070 (1)

    Genetic Association Database (GAD): SULT1A2
    Human Genome Epidemiology (HuGE) Navigator: SULT1A2 (18 documents)

    Export disorders for SULT1A2 gene to outside databases

    Publications
    for SULT1A2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SULT1A2 gene, integrated from 9 sources (see all 55):
    (articles sorted by number of sources associating them with SULT1A2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Human phenol sulfotransferase STP2 gene: molecular cloning, structural characterization, and chromosomal localization. (PubMed id 8661000)1, 2, 3, 9 Her C.... Weinshilboum R.M. (1996)
    2. Genomic organization and DNA sequences of two human phenol sulfotransferase genes (STP1 and STP2) on the short arm of chromosome 16. (PubMed id 8912648)1, 2, 3, 9 Dooley T.P. and Huang Z. (1996)
    3. Cloning, structural organization, and chromosomal mapping of the human phenol sulfotransferase STP2 gene. (PubMed id 9119390)1, 2, 9 Gaedigk A.... Grant D.M. (1997)
    4. cDNA cloning and expression of a new form of human aryl sulfotransferase. (PubMed id 8697101)1, 2, 9 Zhu X.... McManus M.E. (1996)
    5. A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. (PubMed id 12419832)1, 4, 9 Sachse C....Wolf C.R. (2002)
    6. Crystal structures of SULT1A2 and SULT1A1 *3: insight s into the substrate inhibition and the role of Tyr149 in SULT1A2. (PubMed id 20417180)1, 2 Lu J....Chang W. (2010)
    7. Genetic polymorphisms and linkage disequilibrium of sulfotransferase SULT1A1 and SULT1A2 in a Korean population: comparison of other ethnic groups. (PubMed id 16133548)1, 4 Kim K.A....Park J.Y. (2005)
    8. The relationship among the polymorphisms of SULT1A1, 1A2 and different types of cancers in Taiwanese. (PubMed id 12469224)1, 4 Peng C.T....Chang J.G. (2003)
    9. Sulfotransferase 1A2*2 is a risk factor for early-onset breast cancer. (PubMed id 12373301)1, 4 Hou M.F....Chang J.G. (2002)
    10. Sulfation pharmacogenetics: SULT1A1 and SULT1A2 allele frequencies in Caucasian, Chinese and African-American subjects. (PubMed id 11207031)1, 4 Carlini E.J....Weinshilboum R.M. (2001)

    External Searches for SULT1A2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing SULT1A2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6799 HGNC: 11454 AceView: SULT1A2andSULT1A1 Ensembl:ENSG00000197165 euGenes: HUgn6799
    ECgene: SULT1A2 Kegg: 6799 H-InvDB: SULT1A2

    Other Databases showing SULT1A2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SULT1A2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SULT1A2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SULT1A2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SULT1A2 gene:
    Search GeneIP for patents involving SULT1A2

    GeneCards and IP:
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