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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SUGT1 Gene

protein-coding   GIFtS: 56
GCID: GC13P053226

SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)

 Explore 4 diseases affiliated with
SUGT1 via our new
 Human Malady Compendium 
Biological research products
for SUGT1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
SGT1, Suppressor Of G2 Allele Of SKP1 (S. Cerevisiae)1 2     Suppressor Of G2 Allele Of SKP1 Homolog2
SGT11 2     Suppressor Of G2 Allele Of SKP1, S. Cerevisiae, Homolog Of2
Putative 40-6-3 Protein2     Sgt13
SGT1B Protein2     Protein 40-6-33

External Ids:    HGNC: 169871   Entrez Gene: 109102   Ensembl: ENSG000001654167   OMIM: 6040985   UniProtKB: Q9Y2Z03   

Export aliases for SUGT1 gene to outside databases

Previous GC identifers: GC13P047221 GC13P052163 GC13P051024 GC13P051025 GC13P052124 GC13P033941


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SUGT1:
This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required
for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two
transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Aug 2008)

UniProtKB/Swiss-Prot: SUGT1_HUMAN, Q9Y2Z0
Function: May play a role in ubiquitination and subsequent proteasomal degradation of target proteins

Gene Wiki entry for SUGT1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NC_018924.1  NT_024524.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SUGT1 gene promoter:
         AML1a   STAT5A   LCR-F1   FOXL1   HEN1   IRF-2   GATA-6   FOXJ2 (long isoform)   FOXJ2   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SUGT1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SUGT1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUGT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q14.3   Ensembl cytogenetic band:  13q14.3   HGNC cytogenetic band: 13q12.2-q13.3

SUGT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SUGT1 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P053226:  view genomic region     (about GC identifiers)

Start:
53,226,831 bp from pter      End:
53,262,433 bp from pter
Size:
35,603 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SUGT1_HUMAN, Q9Y2Z0 (See protein sequence)
Recommended Name: Suppressor of G2 allele of SKP1 homolog  
Size: 365 amino acids; 41024 Da
Subunit: Probably associates with SCF (SKP1-CUL1-F-box protein) complex through interaction with SKP1. Interacts with
S100A6. Interacts with HSP90
Subcellular location: Cytoplasm. Nucleus. Note=Translocates to the nucleus upon heat shock, requiring S100A6
1 PDB 3D structure from and Proteopedia for SUGT1:
1RL1 (3D)    
Secondary accessions: A2A303 Q5JAK5 Q5TAM6 Q6VXY6
Alternative splicing: 2 isoforms:  Q9Y2Z0-1   Q9Y2Z0-2   

Explore the universe of human proteins at neXtProt for SUGT1: NX_Q9Y2Z0

Post-translational modifications:

  • Phosphorylated at Ser-281 and Ser-331, dephosphorylation promotes nuclear translocation, most likely due to disruption
  • of the SUGT1-HSP90 complex1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y2Z0

  • SUGT1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001124384.1  NP_006695.1  

    ENSEMBL proteins: 
     ENSP00000367208   ENSP00000308067   ENSP00000443521  
    Reactome Protein details: Q9Y2Z0
    Human Recombinant Protein Products: 
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    Novus Biologicals SUGT1 Proteins
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    ProSpec Recombinant Protein for SUGT1
    Uscn Proteins for SUGT1

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000151ubiquitin ligase complex TAS10445024
    GO:0000776kinetochore TAS10445024
    GO:0005634nucleus IEA--
    GO:0005829cytosol TAS--


    SUGT1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SUGT1 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR011990 TPR-like_helical
     IPR007699 SGS
     IPR008978 HSP20-like_chaperone
     IPR017447 CS_domain
     IPR007052 CS-like_domain

    Graphical View of Domain Structure for InterPro Entry Q9Y2Z0

    ProtoNet protein and cluster: Q9Y2Z0

    1 Blocks protein family: IPB007052 CS domain

    UniProtKB/Swiss-Prot: SUGT1_HUMAN, Q9Y2Z0
    Domain: The CS domain mediates interaction with HSP90
    Similarity: Belongs to the SUGT1 family
    Similarity: Contains 1 CS domain
    Similarity: Contains 1 SGS domain
    Similarity: Contains 3 TPR repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: SUGT1_HUMAN, Q9Y2Z0
    Function: May play a role in ubiquitination and subsequent proteasomal degradation of target proteins

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    SwitchGear 3'UTR luciferase reporter plasmidSUGT1 3' UTR sequence
    Inhib. RNA
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    1 GenomeRNAi human phenotype for SUGT1:
     Increased gamma-H2AX phosphory 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1NLRP3 oligomerizes via NACHT domains
    NLRP3 oligomerizes via NACHT domains1.00
    NLRP3 activation by small molecules0.75
    NLRP3 activation by elicitor proteins1.00
    2Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
    Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways1.00
    NOD pathway0.23
    NOD-like receptor signaling pathway0.36
    3Inflammasomes
    Inflammasomes1.00
    The NLRP3 inflammasome0.71
    4Immune System
    Immune System1.00
    Innate Immune System0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for SUGT1 
        NOD pathway

    5/8        Reactome Pathways for SUGT1 (see all 8)
        NLRP3 oligomerizes via NACHT domains
    NLRP3 activation by small molecules
    Inflammasomes
    Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
    NLRP3 activation by elicitor proteins


    1         Kegg Pathway  (Kegg details for SUGT1):
        NOD-like receptor signaling pathway


    SUGT1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SUGT1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/792 Interacting proteins for SUGT1 (Q9Y2Z02, 3 ENSP000003672084) via UniProtKB, MINT, STRING, and/or I2D (see all 792)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAP3K3Q997592, 3MINT-48396 I2D: score=2 
    HSP90AA1P079002, 3, ENSP000003351534MINT-7945693 MINT-7947479 I2D: score=2 STRING: ENSP00000335153
    HSP90B1P146252, 3, ENSP000002997674MINT-7945693 MINT-7947479 I2D: score=1 STRING: ENSP00000299767
    CDC5LQ994592, ENSP000003605324MINT-7945693 MINT-7947479 STRING: ENSP00000360532
    BUB3O436842, ENSP000003578584MINT-7945693 MINT-7947479 STRING: ENSP00000357858
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007067mitosis TAS10445024
    GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway TAS--
    GO:0045087innate immune response TAS--


    SUGT1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SUGT1
    Search CenterWatch for drugs/clinical trials and news about SUGT1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SUGT1 gene (2 alternative transcripts): 
    NM_001130912.1  NM_006704.3  

    Unigene Cluster for SUGT1:

    SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
    Hs.281902  [show with all ESTs]
    Unigene Representative Sequence: NM_001130912
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000483074 ENST00000343788 ENST00000310528 ENST00000535397(uc001vhc.2 uc001vhb.2 uc010thb.1)


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    Additional cDNA sequence: 

    AF132856.1 AJ344097.1 AK291402.1 AK292128.1 AK302363.1 AY271314.1 AY321358.1 BC000911.1 
    BT009798.1 

    13 DOTS entries:

    DT.100780457  DT.65284024  DT.97854428  DT.100731627  DT.95161781  DT.95161797  DT.97854424  DT.120761272 
    DT.120761284  DT.120761294  DT.40121249  DT.92451041  DT.97854425 

    24/212 AceView cDNA sequences (see all 212):

    AA975245 BQ896597 BM849524 BT009798 BM503492 CR610986 BM979808 BU838738 
    AF132856 BE876387 AI471343 BU173965 AI282285 BQ690991 BM727854 BQ685685 
    BU176954 AA773604 BM853595 CA842003 CK300334 AA704143 BM916317 BM788973 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SUGT1    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
    SP1:                    -                                                               
    SP2:                                                                                    
    SP3:                                                                                    


    ECgene alternative splicing isoforms for SUGT1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SUGT1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AACAAATCCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See SUGT1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SUGT1

    SOURCE GeneReport for Unigene cluster: Hs.281902
        SABiosciences Expression via Pathway-Focused PCR Arrays including SUGT1: 
              Antiviral Response in human mouse rat
              Inflammasomes in human mouse rat
              Antibacterial Response in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SUGT1 gene from 10/33 species (see all 33)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sugt11 , 5 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) less1, 5 86.59(n)1
    87.39(a)1
      14 (42.72 cM)5
    679551  NM_026474.51  NP_080750.11 
     795876915 
    chicken
    (Gallus gallus)
    Aves SUGT11 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) less 76.07(n)
    77.3(a)
      418827  NM_001030823.2  NP_001025994.2 
    lizard
    (Anolis carolinensis)
    Reptilia SUGT16
    --
    64(a)
    1 ↔ 1
    3(70784576-70806956)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.252402 Xenopus laevis transcribed sequence with weak similarity to protein refNP_006695.1 (H.sapiens) suppressor of G2 allele of SKP1 [Homo sapiens] less 76.56(n)    CD302381.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufd45a022 Transcribed sequence with moderate similarity to protein refNP_006695.1 (H.sapiens) suppressor of G2 allele of SKP1 [Homo sapiens] less 74.81(n)    57057639 
    fruit fly
    (Drosophila melanogaster)
    Insecta Sgt11 CG9617-PA 54.34(n)
    49.71(a)
      40982  NM_141526.3  NP_649783.2 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_D1054.31 Protein D1054.3 51.61(n)
    40.86(a)
      179494  NM_073350.3  NP_505751.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SGT11 Sgt1p 53.65(n)
    41.18(a)
      854222   NP_014700.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SGT1B1 phosphatase SGT1b 50.5(n)
    40.12(a)
      826728  NM_117197.3  NP_192865.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g06245001 hypothetical protein 50.75(n)
    40.17(a)
      4326682  NM_001050155.1  NP_001043620.1 


    ENSEMBL Gene Tree for SUGT1 (if available)
    TreeFam Gene Tree for SUGT1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SUGT1 gene
    2 SIMAP similar genes for SUGT1 using alignment to 2 protein entries:     SUGT1_HUMAN (see all proteins):
    SUGT1P3    OK/SW-cl.41

    SUGT1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for SUGT1
    PGOHUM00000238672 PGOHUM00000237985


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/601 NCBI SNPs in SUGT1 are shown (see all 601    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs95362181,2
    C,F,H,--33939275(+) cttacG/Actgta 2 -- us2k19Minor allele frequency- A:0.02NS EA NA WA 646
    rs783732271,2
    --33939770(+) GTGGAC/TTGCAA 2 -- us2k10--------
    rs751121461,2
    F,--33939948(+) TAAATA/TCTCAA 2 -- us2k11Minor allele frequency- T:0.05WA 118
    rs12999371,2
    H--33940223(-) gtattT/Cctagg 2 -- us2k15Minor allele frequency- C:0.01MN NS EA 604
    rs740873911,2
    C,--33940716(+) CACGCG/ATCATC 2 -- us2k12Minor allele frequency- A:0.06WA 120
    rs731864261,2
    C,--33940922(+) CTAAAA/GTACTA 2 -- us2k10--------
    rs769473351,2
    F,--33940960(+) GCGTGG/CGCGCG 2 -- us2k11Minor allele frequency- C:0.03WA 118
    rs95914581,2
    C,--33941192(+) CAGAAG/CTTTCC 2 -- ut51 ese34Minor allele frequency- C:0.07NA WA 124
    rs2014125721,2
    C--33942197(-) GGTTTC/TCTCTT 2 -- int10--------
    rs95362211,2
    C,F,--33942454(+) TTATTA/GGAGGG 2 -- int14Minor allele frequency- G:0.04NA WA 124

    HapMap Linkage Disequilibrium report for SUGT1 (53226831 - 53262433 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for SUGT1
         2 CNVs: 58633 59596

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SUGT1 for disorders           About GeneDecksing

    OMIM gene information: 604098    OMIM disorders: --

    4 diseases for SUGT1:    About MalaCards
    polydactyly    colorectal cancer    lung cancer    malaria

    1 Novoseek disease relationship for SUGT1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    plant diseases 77.2 3 11847308 (1), 14761955 (1), 12456004 (1)


    Export disorders for SUGT1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SUGT1 gene, integrated from 9 sources (see all 45):
    (articles sorted by number of sources associating them with SUGT1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex. (PubMed id 10445024)1, 2, 3 Kitagawa K.... Hieter P. (1999)
    2. Human Sgt1 binds HSP90 through the CHORD-Sgt1 domain and not the tetratricopeptide repeat domain. (PubMed id 14761955)1, 2, 9 Lee Y.-T....Chazin W.J. (2004)
    3. Identification of a novel splice variant: human SGT1B (SUGT1B). (PubMed id 15018354)1, 2, 9 Niikura Y. and Kitagawa K. (2003)
    4. Nuclear translocation of Sgt1 depends on its phosphorylation state. (PubMed id 21864708)1, 2 Prus W.... Filipek A. (2011)
    5. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
    8. Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins. (PubMed id 12746458)1, 2 Nowotny M....Kuznicki J. (2003)
    9. Overexpression of SUGT1 in human colorectal cancer an d its clinicopathological significance. (PubMed id 20126976)1, 9 Iwatsuki M....Mori M. (2010)
    10. Hsp90-Sgt1 and Skp1 target human Mis12 complexes to e nsure efficient formation of kinetochore-microtubule binding sites. (PubMed id 20404110)1, 9 Davies A.E. and Kaplan K.B. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10910 HGNC: 16987 AceView: SUGT1 Ensembl:ENSG00000165416 euGenes: HUgn10910
    ECgene: SUGT1 Kegg: 10910 H-InvDB: SUGT1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SUGT1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SUGT1 gene:
    Search GeneIP for patents involving SUGT1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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