Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SUGP2 Gene

protein-coding   GIFtS: 54
GCID: GC19M019103

SURP And G Patch Domain Containing 2

(Previous names: splicing factor, arginine/serine-rich 14)
(Previous symbol: SFRS14)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
SURP And G Patch Domain Containing 21 2     Arginine/Serine-Rich 14 Splicing Factor2
Splicing Factor, Arginine/Serine-Rich 141 2 3     Putative Splicing Factor, Arginine/Serine-Rich 142
SFRS141 2 3     SURP And G-Patch Domain-Containing Protein 22
Arginine/Serine-Rich-Splicing Factor 142 3     SRFS145
KIAA03653 5     

External Ids:    HGNC: 186411   Entrez Gene: 101472   Ensembl: ENSG000000646077   OMIM: 6079935   UniProtKB: Q8IX013   

Export aliases for SUGP2 gene to outside databases

Previous GC identifer: GC19M018665


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for SUGP2 Gene:
This gene encodes a member of the arginine/serine-rich family of splicing factors. The encoded protein functions
in mRNA processing. Alternatively spliced transcript variants have been described. (provided by RefSeq, Feb 2009)

GeneCards Summary for SUGP2 Gene:
SUGP2 (SURP and G patch domain containing 2) is a protein-coding gene. GO annotations related to this gene include RNA binding. An important paralog of this gene is SUGP1.

UniProtKB/Swiss-Prot: SUGP2_HUMAN, Q8IX01
Function: May play a role in mRNA splicing (Potential)

Gene Wiki entry for SUGP2 (SFRS14) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011295.12  NC_018930.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for SUGP2
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SUGP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SUGP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p12   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p13

SUGP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SUGP2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M019103:  view genomic region     (about GC identifiers)

Start:
19,101,697 bp from pter      End:
19,144,832 bp from pter
Size:
43,136 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SUGP2_HUMAN, Q8IX01 (See protein sequence)
Recommended Name: SURP and G-patch domain-containing protein 2  
Size: 1082 amino acids; 120207 Da
Sequence caution: Sequence=AAC06129.1; Type=Erroneous gene model prediction; Sequence=AAH20586.1; Type=Erroneous
initiation; Note=Translation N-terminally extended; Sequence=BAA20820.2; Type=Erroneous initiation;
Note=Translation N-terminally shortened;
1 PDB 3D structure from and Proteopedia for SUGP2:
1X4P (3D)    
Secondary accessions: C9JI71 O15071 O60369 Q5JPH7 Q8WUF7
Alternative splicing: 3 isoforms:  Q8IX01-1   Q8IX01-3   Q8IX01-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SUGP2: NX_Q8IX01

Explore proteomics data for SUGP2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys137, Lys228, Lys305, Lys595, Lys650, Lys673
  • Modification sites at PhosphoSitePlus

  • See SUGP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001017392.2  NP_055699.2  

    ENSEMBL proteins: 
     ENSP00000472183   ENSP00000470915   ENSP00000332373   ENSP00000337926   ENSP00000389380  
     ENSP00000473187   ENSP00000472286   ENSP00000472914   ENSP00000472878   ENSP00000472244  
     ENSP00000471042   ENSP00000409603  

    SUGP2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for SUGP2
    OriGene Custom MassSpec
    OriGene Custom Protein Services for SUGP2
    GenScript Custom Purified and Recombinant Proteins Services for SUGP2
    Novus Biologicals SUGP2 Protein
    Novus Biologicals SUGP2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SUGP2

     
    Search eBioscience for Proteins for SUGP2 

     
    antibodies-online proteins for SUGP2 (2 products) 

     
    antibodies-online peptides for SUGP2

    SUGP2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for SUGP2
    OriGene Custom Antibody Services for SUGP2
    Novus Biologicals SUGP2 Antibodies
    Search for Antibodies for SUGP2 at Abcam
    Cloud-Clone Corp. Antibodies for SUGP2
    Search ThermoFisher Antibodies for SUGP2
    antibodies-online antibodies for SUGP2 (30 products) 

    SUGP2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SUGP2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SUGP2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SUGP2
    Cloud-Clone Corp. CLIAs for SUGP2
    Search eBioscience for ELISAs for SUGP2 
    antibodies-online kits for SUGP2 (3 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    GPATCH: G patch domain containing

    2 InterPro protein domains:
     IPR000467 G_patch_dom
     IPR000061 Surp

    Graphical View of Domain Structure for InterPro Entry Q8IX01

    ProtoNet protein and cluster: Q8IX01

    2 Blocks protein domains:
    IPB000061 SWAP/Surp
    IPB000467 D111/G-patch domain


    UniProtKB/Swiss-Prot: SUGP2_HUMAN, Q8IX01
    Similarity: Contains 1 G-patch domain
    Similarity: Contains 2 SURP motif repeats


    Find genes that share domains with SUGP2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SUGP2_HUMAN, Q8IX01
    Function: May play a role in mRNA splicing (Potential)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with SUGP2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SUGP2:
     Increased S DNA content 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for SUGP2

    miRNA
    Products:
        
    miRTarBase miRNAs that target SUGP2:
    hsa-mir-125b-5p (MIRT046029), hsa-let-7e-5p (MIRT051552), hsa-mir-484 (MIRT042295)

    Block miRNA regulation of human, mouse, rat SUGP2 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate SUGP2:
    hsa-miR-362-3p hsa-miR-892b hsa-miR-149 hsa-miR-3941 hsa-miR-329 hsa-miR-4308
    SwitchGear 3'UTR luciferase reporter plasmidSUGP2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SUGP2
    Predesigned siRNA for gene silencing in human, mouse, rat SUGP2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SUGP2

    Clone
    Products:
         
    OriGene clones in human, mouse for SUGP2 (see all 12)
    OriGene ORF clones in mouse, rat for SUGP2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SUGP2 (NM_001017392)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SUGP2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUGP2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SUGP2
    Browse ESI BIO Cell Lines and PureStem Progenitors for SUGP2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUGP2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    SUGP2_HUMAN, Q8IX01: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with SUGP2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for SUGP2 About    
    See pathways by source

    SuperPathContained pathways About
    1mRNA Splicing - Major Pathway
    mRNA processing0.44


    1 BioSystems Pathway for SUGP2
        mRNA processing


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SUGP2
    Interactions:

        Search GeneGlobe Interaction Network for SUGP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for SUGP2 (Q8IX012, 3 ENSP000003379264) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN1P542532, 3, ENSP000002447694MINT-2868027 I2D: score=3 STRING: ENSP00000244769
    LZTR1Q8N6533, ENSP000002157394I2D: score=1 STRING: ENSP00000215739
    NR4A2P433543I2D: score=1 
    PPP2R2BENSP000003365914STRING: ENSP00000336591
    HNRNPA1ENSP000003418264STRING: ENSP00000341826
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006396RNA processing ----
    GO:0006397mRNA processing IEA--
    GO:0008380RNA splicing IEA--

    Find genes that share ontologies with SUGP2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SUGP2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SUGP2 gene (2 alternative transcripts): 
    NM_001017392.3  NM_014884.3  

    Unigene Cluster for SUGP2:

    SURP and G patch domain containing 2
    Hs.515271  [show with all ESTs]
    Unigene Representative Sequence: AK074842
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000593795 ENST00000594773 ENST00000597095 ENST00000597163 ENST00000330854
    ENST00000337018(uc002nkx.2) ENST00000598863 ENST00000452918(uc002nkz.1 uc002nla.1 uc002nlb.2)
    ENST00000600239 ENST00000601879 ENST00000600377 ENST00000597280 ENST00000598240
    ENST00000598202 ENST00000594445 ENST00000456085(uc010xqk.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SUGP2 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate SUGP2:
    hsa-miR-362-3p hsa-miR-892b hsa-miR-149 hsa-miR-3941 hsa-miR-329 hsa-miR-4308
    SwitchGear 3'UTR luciferase reporter plasmidSUGP2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SUGP2
    Predesigned siRNA for gene silencing in human, mouse, rat SUGP2
    Clone
    Products:
         
    OriGene clones in human, mouse for SUGP2 (see all 12)
    OriGene ORF clones in mouse, rat for SUGP2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SUGP2 (NM_001017392)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SUGP2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUGP2
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SUGP2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SUGP2
      QuantiTect SYBR Green Assays in human, mouse, rat SUGP2
      QuantiFast Probe-based Assays in human, mouse, rat SUGP2

    Additional mRNA sequence: 

    AF518874.1 AK025508.1 AK074842.1 AK291275.1 AK299860.1 AL832488.1 BX647813.1 BX647933.1 
    CR627095.1 

    Selected DOTS entries (see all 25):

    DT.99953055  DT.95156916  DT.100037663  DT.92447724  DT.319513  DT.95356501  DT.95356502  DT.100827360 
    DT.95302583  DT.100827350  DT.100827361  DT.100827356  DT.100037662  DT.100037661  DT.87017193  DT.92447743 
    DT.95356521  DT.121472332  DT.100827348  DT.92447734  DT.100827362  DT.121472336  DT.92447747  DT.100827355 

    Selected AceView cDNA sequences (see all 489):

    AL832488 AL706031 CB111559 BM463446 CA310204 CN481568 BQ719873 AB002363 
    AI582613 BM792298 BF475525 AU126349 AW612872 AL044760 BM710189 BX480470 
    BF914770 Z39492 CD671613 AI559985 BQ446755 AI610737 AI420717 BM556728 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SUGP2 (see all 11)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b ^
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                -     -                     
    SP3:                                                                                                                                -     -                     
    SP4:                                                                                                                                                            
    SP5:        -     -     -                                                                                                                                       

    ExUns: 15 ^ 16
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for SUGP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SUGP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SUGP2 Expression
    About this image


    SUGP2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Bone (Muscoskeletal System)
             Bone Marrow
    SUGP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SUGP2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.515271

    UniProtKB/Swiss-Prot: SUGP2_HUMAN, Q8IX01
    Tissue specificity: Detected in adult testis, and in fetal brain and kidney

        Custom PCR Arrays for SUGP2
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for SUGP2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SUGP2
    QuantiTect SYBR Green Assays in human, mouse, rat SUGP2
    QuantiFast Probe-based Assays in human, mouse, rat SUGP2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUGP2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for SUGP2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sugp21 , 5 SURP and G patch domain containing 21, 5 77.45(n)1
    75.97(a)1
      8 (34.15 cM)5
    2343731  NM_172755.31  NP_766343.31 
     702342265 
    chicken
    (Gallus gallus)
    Aves SUGP21 SURP and G patch domain containing 2 63.01(n)
    59.18(a)
      420113  NM_001195569.1  NP_001182498.1 
    lizard
    (Anolis carolinensis)
    Reptilia SUGP26
    SURP and G patch domain containing 2
    52(a)
    1 ↔ 1
    AAWZ02041141(1441-2784)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.293392 Xenopus laevis transcribed sequence with weak similarity more 74.44(n)    48049621 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG315506
    --
    12(a)
    1 → many
    3R(1311254-1315211)


    ENSEMBL Gene Tree for SUGP2 (if available)
    TreeFam Gene Tree for SUGP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for SUGP2 gene
    SUGP12  
    1 SIMAP similar gene for SUGP2 using alignment to 8 protein entries:     SUGP2_HUMAN (see all proteins):
    DKFZp779L2418

    Find genes that share paralogs with SUGP2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SUGP2 (see all 924)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs582825701,2
    C--18677490(+) TTTTT-/T/TT  
            
    GAGAC
    2 -- int11NA 2
    rs133452461,2
    C,F,A,H--19101218(+) GGGACA/GGCAGG 1 -- ds50015Minor allele frequency- G:0.06NS EA WA 538
    rs1130317191,2
    F--19101381(+) ACTGCC/TCTGAC 1 -- ds50012Minor allele frequency- T:0.04CSA WA 120
    rs748759591,2
    C,F--19101453(+) GGGAAT/CTGCCC 1 -- ds50011Minor allele frequency- C:0.03WA 118
    rs1828348801,2
    --19101461(+) CCCTCC/TCTCTG 1 -- ds50010--------
    rs1871839681,2
    --19101567(+) GGGCCC/TGAGGG 1 -- ds50010--------
    rs1169194331,2
    C,F--19101584(+) ACCACG/ACCGGC 1 -- ds50011Minor allele frequency- A:0.04EA 120
    rs1158212491,2
    F--19101618(+) CCATCA/TTCTGG 1 -- ds50011Minor allele frequency- T:0.02WA 118
    rs1145420001,2
    C,F--19101664(+) CTGATC/ATGATT 1 -- ds50011Minor allele frequency- A:0.04WA 118
    rs1916408951,2
    --19101728(+) GCAACA/GGCTAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SUGP2 (19101697 - 19144832 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SUGP2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv2435CNV Loss18451855
    nsv833778CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SUGP2
    DNA2.0 Custom Variant and Variant Library Synthesis for SUGP2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 607993    OMIM disorders: --


    Find genes that share disorders with SUGP2           About GenesLikeMe


    Export disorders for SUGP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SUGP2 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with SUGP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. SF4 and SFRS14, two related putative splicing factors on human chromosome 19p13.11. (PubMed id 12594045)1, 2, 3, 9 Sampson N.D. and Hewitt J.E. (Gene 2003)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (Nature 2004)
    4. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2 Nagase T.... Ohara O. (DNA Res. 1997)
    5. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (PLoS ONE 2013)
    6. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    7. DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation. (PubMed id 22446626)1 Close P.... Svejstrup J.Q. (Nature 2012)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 10147 HGNC: 18641 AceView: SFRS14 Ensembl:ENSG00000064607 euGenes: HUgn10147
    ECgene: SUGP2 H-InvDB: SUGP2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA0365

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SUGP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SUGP2 gene:
    Search GeneIP for patents involving SUGP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for SUGP2   OriGene RNAi products in human, mouse, rat for SUGP2  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for SUGP2  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SUGP2  
     OriGene qSTAR qPCR primer pairs in human, mouse for SUGP2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SUGP2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SUGP2   OriGene Custom Protein Services for SUGP2  

     
     
     Block miRNA regulation of human, mouse, rat SUGP2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SUGP2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SUGP2 Predesigned siRNA for gene silencing in human, mouse, rat SUGP2
     QuantiFast Probe-based Assays in human, mouse, rat SUGP2 QuantiTect SYBR Green Assays in human, mouse, rat SUGP2
     Custom PCR Arrays for SUGP2 Search Chromatin IP Primers for SUGP2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SUGP2  Search GeneGlobe Interaction Network for SUGP2
     Search Regulatory tfbs for SUGP2
     GenScript Custom Purified and Recombinant Proteins Services for SUGP2 GenScript cDNA clones with any tag delivered in your preferred vector for SUGP2
     GenScript Custom Assay Services for SUGP2 GenScript Custom overexpressing Cell Line Services for SUGP2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SUGP2
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SUGP2 antibodies
     SUGP2 proteins
     SUGP2 lysates
     Search for Antibodies for SUGP2 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for SUGP2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SUGP2
     Antibodies for SUGP2
     ELISAs for SUGP2
     CLIAs for SUGP2



     Browse ESI BIO Cell Lines and PureStem Progenitors for SUGP2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUGP2
     SwitchGear 3'UTR luciferase reporter plasmids for SUGP2
     Browse SwitchGear Promoter luciferase reporter plasmids for SUGP2
     Search ThermoFisher Antibodies for SUGP2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUGP2
     Browse compounds at ApexBio
     Search Addgene for plasmids for SUGP2
      Search eBioscience for proteins for SUGP2
      Search eBioscience for elisas for SUGP2
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for SUGP2
     antibodies-online antibodies for SUGP2 (30 products)
     antibodies-online kits for SUGP2 (3 products)
     antibodies-online peptides for SUGP2
     antibodies-online proteins for SUGP2 (2 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SUGP2 gene at Home site.
    Version: 3.12.250 16 Nov 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4