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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SUCNR1 Gene

protein-coding GIFtS: 50
GCID: GC03P151591

succinate receptor 1

(Previous name: G protein-coupled receptor 91 )
(Previous symbol: GPR91)

Explore 5 diseases affiliated with
SUCNR1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Succinate Receptor 1¹ ²
GPR91¹ ² ³ ⁵
G Protein-Coupled Receptor 91¹ ²
G-Protein Coupled Receptor 91² ³
P2Y Purinoceptor 1²
P2Y Purinoceptor 1-Like³

External Ids:	HGNC: 4542¹	Entrez Gene: 56670²	Ensembl: ENSG00000198829⁷	OMIM: 606381⁵	UniProtKB: Q9BXA5³

Export aliases for SUCNR1 gene to outside databases

Previous GC identifers: GC03P153074 GC03P148982

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SUCNR1:

This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is

involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular

hypertension which has known correlations to renal failure, diabetes and atherosclerosis. (provided by RefSeq, Oct

2009)

UniProtKB/Swiss-Prot: SUCR1_HUMAN, Q9BXA5

Function: Receptor for succinate

Gene Wiki entry for SUCNR1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000003.11 NC_018914.1 NT_005612.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SUCNR1 gene promoter:
RelA POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) Nkx2-5 CUTL1 POU3F2 HNF-1A MEF-2A HNF-1 aMEF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SUCNR1 promoter sequence

Search SABiosciences Chromatin IP Primers for SUCNR1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUCNR1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q25.1 Ensembl cytogenetic band: 3q25.1 HGNC cytogenetic band: 3q25.1

SUCNR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SUCNR1 gene location

GeneLoc information about chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03P151591: view genomic region (about GC identifiers)

Start:	151,591,431 bp from pter	End:	151,599,876 bp from pter
Size:	8,446 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SUCR1_HUMAN, Q9BXA5 (See protein sequence)

Recommended Name: Succinate receptor 1

Size: 334 amino acids; 38698 Da

Subcellular location: Cell membrane; Multi-pass membrane protein

Caution: It is uncertain whether Met-1 or Met-5 is the initiator

Sequence caution: Sequence=AAK29080.1; Type=Erroneous initiation;

Secondary accessions: A8K305 Q8TDQ8

Explore the universe of human proteins at neXtProt for SUCNR1: NX_Q9BXA5

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9BXA5

SUCNR1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_149039.2

ENSEMBL proteins:

ENSP00000355156

Human Recombinant Protein Products for SUCNR1:

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	Uscn Proteins for SUCNR1

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0016021	integral to membrane	NAS	--

SUCNR1 for ontologies About GeneDecksing

SUCNR1 Antibody Products:

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Assay Products for SUCNR1:

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	Uscn ELISAs and CLIAs for SUCNR1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SUCNR1 for domains About GeneDecksing

3 InterPro domains/families:

IPR017452 GPCR_Rhodpsn_7TM

IPR000276 GPCR_Rhodpsn

IPR002286 P2_purnocptor

Graphical View of Domain Structure for InterPro Entry Q9BXA5

ProtoNet protein and cluster: Q9BXA5

UniProtKB/Swiss-Prot: SUCR1_HUMAN, Q9BXA5

Similarity: Belongs to the G-protein coupled receptor 1 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: SUCR1_HUMAN, Q9BXA5

Function: Receptor for succinate

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0045028	G-protein coupled purinergic nucleotide receptor activity	IEA	--

SUCNR1 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for SUCNR1:

Increased circadian period len

5 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Sucnr1):

cellular

hematopoietic system

homeostasis/metabolism

immune system

renal/urinary system

SUCNR1 for phenotypes About GeneDecksing

Animal Models:
Mouse knock-outs for SUCNR1: Sucnr1^tm1Dgen Sucnr1^tm1Lex

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SUCNR1

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SUCNR1
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate SUCNR1:
		hsa-miR-330-5p hsa-miR-326
		SwitchGear 3'UTR luciferase reporter plasmid: SUCNR1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SUCNR1 (see all 7) OriGene shRNA RFP: SUCNR1 OriGene siRNA: SUCNR1
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		Sirion Biotech Custom design and validation of potent shRNA sequences against SUCNR1

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for SUCNR1
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Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUCNR1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUCNR1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: SUCNR1 (NM_033050)
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUCNR1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Class A/1 (Rhodopsin-like receptors)

GPCRs, Class A Rhodopsin-like

0.41

1 BioSystems Pathway for SUCNR1

GPCRs, Class A Rhodopsin-like

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SUCNR1

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--

SUCNR1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SUCNR1

1 DrugBank Compound for SUCNR1 About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
Succinic acid	1,2-Ethanedicarboxylic acid (see all 8)	110-15-6	target	--	17192395

Search CenterWatch for drugs/clinical trials and news about SUCNR1 / SUCR1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SUCNR1 gene:

NM_033050.4

Unigene Cluster for SUCNR1:

Succinate receptor 1

Hs.279575 [show with all ESTs]

Unigene Representative Sequence: NM_033050

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000362032(uc003ezf.2)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SUCNR1
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate SUCNR1:
		hsa-miR-330-5p hsa-miR-326
		SwitchGear 3'UTR luciferase reporter plasmid: SUCNR1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SUCNR1 (see all 7) OriGene shRNA RFP: SUCNR1 OriGene siRNA: SUCNR1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SUCNR1
		Sirion Biotech Custom design and validation of potent shRNA sequences against SUCNR1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUCNR1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUCNR1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: SUCNR1 (NM_033050)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SUCNR1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUCNR1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SUCNR1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUCNR1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUCNR1

Additional cDNA sequence:

AF247785.1 AF348078.1 AK290420.1 BC030948.1 EU432110.1

1 DOTS entry:

DT.75176203

10 AceView cDNA sequences:

AF348078 BX281458 BF196066 NM_033050 AF247785 AI247270 BG402029 BC030948

BE221739 AW612141

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SUCNR1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

SUCNR1 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Inner Nuclear Layer

Mature Horizontal Cells

Horizontal, Retina

Adipose

Visceral White Adipose

Adipose

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ endothelial progenitor 30-SM2-1 (Embryonic Progenitor Cell)

Endothelium

See SUCNR1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SUCNR1

SOURCE GeneReport for Unigene cluster: Hs.279575

UniProtKB/Swiss-Prot: SUCR1_HUMAN, Q9BXA5

Tissue specificity: Expressed specifically in kidney

SABiosciences Expression via Pathway-Focused PCR Array including SUCNR1:

G Protein Coupled Receptors 384HT in human mouse rat

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		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SUCNR1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUCNR1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SUCNR1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUCNR1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for SUCNR1 gene from 1/7 species (see all 7) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	SUCNR1¹	succinate receptor 1	63.78(n) 63.32(a)		771768 XM_001235005.2 XP_001235006.1

ENSEMBL Gene Tree for SUCNR1 (if available)
TreeFam Gene Tree for SUCNR1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SUCNR1 gene

OXGR1² P2RY4² GPR17² P2RY1² P2RY11² P2RY6² GPR174² LPAR6²

LPAR5² CYSLTR1² GPR183² LPAR4² CYSLTR2² P2RY10² P2RY2² PTAFR²

11 SIMAP similar genes for SUCNR1 using alignment to 1 protein entry: SUCR1_HUMAN:

OXGR1 CYSLTR1 P2RY1 GPR17 CYSLTR2 KPG_011

P2RY4 AGTR1 P2RY2 P2RY6 GPR174

SUCNR1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs187774062^1,2		--	151589452(+)	`CCAGCC/TTTGTT`	1	--	us2k¹		0	--	--	--	--
rs116392743^1,2	F	--	151589503(+)	`TAGCAG/CAAATA`	1	--	us2k¹		1		WA	118
rs138636594^1,2		--	151589618(+)	`GGCTAC/TAGTCT`	1	--	us2k¹		0	--	--	--	--
rs149254534^1,2		--	151589746(+)	`ACCCCA/TCAAAG`	1	--	us2k¹		0	--	--	--	--
rs1402012^1,2	C,F,O,A,H	--	151589783(+)	`AATGGT/CGGCAG`	1	--	us2k¹		20		NS EA NA CSA WA	2262
rs79906316^1,2	C,F	--	151590115(+)	`TGCAAT/CCTTGA`	1	--	us2k¹		2		WA NA	238
rs73018428^1,2	C,F	--	151590220(+)	`TTGATG/ACATAA`	1	--	us2k¹		6		WA CSA NA EA	364
rs144479074^1,2		--	151590245(+)	`ATACCG/TGCCTG`	1	--	us2k¹		0	--	--	--	--
rs150040435^1,2	C	--	151590305(+)	`TGCAC-/ATGTTTG`	1	--	us2k¹		0	--	--	--	--
rs148014195^1,2		--	151590332(+)	`ATACAA/TGTATA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SUCNR1 (151591431 - 151599876 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SUCNR1
2 CNVs: 53229 3457

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SUCNR1

DNA2.0 Custom Variant and Variant Library Synthesis for SUCNR1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SUCNR1 for disorders           About GeneDecksing

OMIM gene information: 606381    OMIM disorders: --

5 diseases for SUCNR1:    About MalaCards

renovascular hypertension hypertension atherosclerosis retinopathy of prematurity

hematopoiesis

Export disorders for SUCNR1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SUCNR1 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with SUCNR1)

Utopia: connect your pdf to the dynamic
world of online information

Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins. (PubMed id 17192395)^{1, 3, 7} Macaulay I.C....Ouwehand W.H. (2007)
Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors. (PubMed id 15141213)^{1, 2, 3} He W....Ling L. (2004)
An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors. (PubMed id 11273702)^{1, 2, 3} Wittenberger T.... Hellebrand S. (2001)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Neovascularization in retinopathy of prematurity: oppo sing actions of neuronal factors GPR91 and semaphorins 3A. (PubMed id 22497252)¹ Joyal J.S....Chemtob S. (2012)
Association of IFIH1 and other autoimmunity risk alle les with selective IgA deficiency. (PubMed id 20694011)¹ Ferreira R.C....HammarstrAPm L. (2010)
The role of the GPR91 ligand succinate in hematopoiesis. (PubMed id 19204147)¹ Hakak Y....Behan D.P. (2009)
The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)² Muzny D.M....Gibbs R.A. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)² Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 56670	HGNC: 4542	AceView: SUCNR1	Ensembl:ENSG00000198829	euGenes: HUgn56670
ECgene: SUCNR1	H-InvDB: SUCNR1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SUCNR1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SUCNR1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for SUCNR1 gene:
Search GeneIP for patents involving SUCNR1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	Browse OriGene Antibodies		OriGene shRNA RFP for SUCNR1
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SUCNR1		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SUCNR1
	OriGene Protein Over-expression Lysate for SUCNR1		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for SUCNR1		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SUCNR1		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SUCNR1
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
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	OriGene Custom Antibody Services for SUCNR1		OriGene Custom Protein Services for SUCNR1
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SUCNR1
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SUCNR1
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SUCNR1
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	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SUCNR1

	GenScript Custom Purified and Recombinant Proteins Services for SUCNR1		GenScript cDNA clones with any tag delivered in your preferred vector for SUCNR1
	GenScript Custom Assay Services for SUCNR1		GenScript Custom Superior Antibodies Services for SUCNR1
	GenScript Custom overexpressing Cell Line Services for SUCNR1		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
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	Regulatory tfbs in SUCNR1 promoter
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
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SUCNR1 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for SUCNR1

	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SUCNR1

	SwitchGear 3'UTR luciferase reporter plasmids for SUCNR1
	SwitchGear Promoter luciferase reporter plasmids for SUCNR1

ThermoFisher Antibodies for SUCNR1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SUCNR1

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SUCNR1

Sirion Biotech Customized:

	stable knockdown cell line services for SUCNR1
	inducible knockdown cell line services for SUCNR1
	design and validation of potent shRNA sequences against SUCNR1
	adenovirus for potent knockdown of SUCNR1
	adenovirus for overexpression of SUCNR1
	stable overexpressing cell line services for SUCNR1
	inducible overexpressing cell line services for SUCNR1

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes SUCNR1 gene at Home site.

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SUCNR1 Gene

succinate receptor 1

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SUCNR1 Gene

succinate receptor 1

Aliasesfor SUCNR1 gene

Summariesfor SUCNR1 gene

Genomic Viewsfor SUCNR1 gene

Proteinsfor SUCNR1 gene

Protein Domains /Familiesfor SUCNR1 gene

Functionfor SUCNR1 gene

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Genome Databases showing SUCNR1 gene

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Summaries
for SUCNR1 gene

Genomic Views
for SUCNR1 gene

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for SUCNR1 gene

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Families
for SUCNR1 gene

Function
for SUCNR1 gene

Pathways & Interactions
for SUCNR1 gene

Drugs & Compounds
for SUCNR1 gene

Transcripts
for SUCNR1 gene

Expression
for SUCNR1 gene

Orthologs
for SUCNR1 gene

Paralogs
for SUCNR1 gene

Genomic Variants
for SUCNR1 gene

Disorders / Diseases
for SUCNR1 gene

Publications
for SUCNR1 gene

Intellectual Property
for SUCNR1 gene

Products
for SUCNR1 gene