Aliases for STYX Gene
External Ids for STYX Gene
Previous GeneCards Identifiers for STYX Gene
The protein encoded by this gene is a pseudophosphatase, able to bind potential substrates but lacking an active catalytic loop. The encoded protein may be involved in spermiogenesis. Two transcript variants encoding the same protein have been found for these genes. [provided by RefSeq, Oct 2011]
GeneCards Summary for STYX Gene
STYX (Serine/Threonine/Tyrosine Interacting Protein) is a Protein Coding gene. Diseases associated with STYX include diabetes mellitus, insulin-dependent. GO annotations related to this gene include phosphatase activity and protein tyrosine/serine/threonine phosphatase activity. An important paralog of this gene is DUSP26.
UniProtKB/Swiss-Prot for STYX Gene
Catalytically inactive phosphatase. Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2). Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2). Seems to play a role in spermiogenesis (By similarity).