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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STYX Gene

protein-coding   GIFtS: 48
GCID: GC14P053196

serine/threonine/tyrosine interacting protein

(Previous name: serine/threonine/tyrosine-interacting protein )
 Explore 11 diseases affiliated with
STYX via our new
 Human Malady Compendium 
Biological research products
for STYX
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Serine/Threonine/Tyrosine Interacting Protein1 2
Serine/Threonine/Tyrosine-Interacting Protein1 2
Protein Tyrosine Phosphatase-Like Protein2 3

External Ids:    HGNC: 114471   Entrez Gene: 68152   Ensembl: ENSG000001982527   UniProtKB: Q8WUJ03   

Export aliases for STYX gene to outside databases

Previous GC identifers: GC00U990358 GC14P046992 GC14P051186 GC14P052266 GC14P033357


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for STYX:
The protein encoded by this gene is a pseudophosphatase, able to bind potential substrates but lacking an active
catalytic loop. The encoded protein may be involved in spermiogenesis. Two transcript variants encoding the same
protein have been found for these genes. (provided by RefSeq, Oct 2011)

UniProtKB/Swiss-Prot: STYX_HUMAN, Q8WUJ0
Function: Probable pseudophosphatase. Contains a Gly residue instead of a conserved Cys residue in the dsPTPase
catalytic loop which renders it catalytically inactive as a phosphatase. The binding pocket is however sufficiently
preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Seems to play a role in
spermiogenesis (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STYX gene promoter:
         AREB6   MEF-2A   Nkx6-1   Bach2   FOXD1   CUTL1   aMEF-2   HNF-3beta   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTYX promoter sequence
   Search SABiosciences Chromatin IP Primers for STYX

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STYX


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Ensembl cytogenetic band:  14q22.1   HGNC cytogenetic band: 14q22.1

STYX Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STYX gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P053196:  view genomic region     (about GC identifiers)

Start:
53,196,883 bp from pter      End:
53,241,716 bp from pter
Size:
44,834 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: STYX_HUMAN, Q8WUJ0 (See protein sequence)
Recommended Name: Serine/threonine/tyrosine-interacting protein  
Size: 223 amino acids; 25492 Da
Subunit: Interacts with CARHSP1/Crhsp-24 (By similarity)
1 PDB 3D structure from and Proteopedia for STYX:
2R0B (3D)    
Secondary accessions: B9EJG0 Q99850

Explore the universe of human proteins at neXtProt for STYX: NX_Q8WUJ0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8WUJ0

  • STYX Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001124173.1  NP_660294.1  

    ENSEMBL proteins: 
     ENSP00000403214   ENSP00000346599  

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    Novus Biologicals STYX Proteins
    Novus Biologicals STYX Lysates
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for STYX
    Uscn Proteins for STYX

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IBA--


    STYX for ontologies           About GeneDecksing



    STYX Antibody Products: 
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    Uscn ELISAs and CLIAs for STYX


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    STYX for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR000387 Tyr/Dual-sp_Pase
     IPR020422 Dual-sp_phosphatase_subgr_cat
     IPR024950 DUSP
     IPR000340 Dual-sp_phosphatase_cat-dom

    Graphical View of Domain Structure for InterPro Entry Q8WUJ0

    ProtoNet protein and cluster: Q8WUJ0

    1 Blocks protein family: IPB000340 Dual specificity protein phosphatase

    UniProtKB/Swiss-Prot: STYX_HUMAN, Q8WUJ0
    Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily
    Similarity: Contains 1 tyrosine-protein phosphatase domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: STYX_HUMAN, Q8WUJ0
    Function: Probable pseudophosphatase. Contains a Gly residue instead of a conserved Cys residue in the dsPTPase
    catalytic loop which renders it catalytically inactive as a phosphatase. The binding pocket is however sufficiently
    preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Seems to play a role in
    spermiogenesis (By similarity)

    miRNA
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    OriGene 3'-UTR Clone (see all 2): STYX
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat STYX
    8/145 QIAGEN miScript miRNA Assays for microRNAs that regulate STYX (see all 145):
    hsa-miR-106a hsa-miR-3074-3p hsa-miR-519a hsa-miR-4275 hsa-miR-298 hsa-miR-200b hsa-miR-92b hsa-miR-374b*
    SwitchGear 3'UTR luciferase reporter plasmidSTYX 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STYX (see all 4)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STYX 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STYX

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008138NOT protein tyrosine/serine/threonine phosphatase activity IKR--


    STYX for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for STYX:
     Decreased G3BP1 protein expres 

    Animal Models:
         Mouse knock-out Styxtm1.1Jedi for STYX
         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Styx):
     reproductive system 

    STYX for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for STYX

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for STYX (Q8WUJ03 ENSP000003465994) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CARHSP1Q9Y2V23, ENSP000003118474I2D: score=2 STRING: ENSP00000311847
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006470NOT protein dephosphorylation IKR--
    GO:0007283spermatogenesis IBA--


    STYX for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    STYX for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STYX
    4 Novoseek chemical compound relationships for STYX gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tyrosine 68.2 35 10644438 (2), 11054553 (2), 10333047 (2), 8826969 (1) (see all 29)
    c-peptide 45.8 1 12017227 (1)
    glutamate 45.5 7 10333047 (2), 12017227 (1), 15804058 (1), 11061548 (1) (see all 6)
    glucose 0 2 10333047 (2)

    Search CenterWatch for drugs/clinical trials and news about STYX 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for STYX gene (2 alternative transcripts): 
    NM_001130701.1  NM_145251.3  

    Unigene Cluster for STYX:

    Serine/threonine/tyrosine interacting protein
    Hs.364980  [show with all ESTs]
    Unigene Representative Sequence: NM_145251
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000442123 ENST00000354586(uc010tqy.2 uc001xaa.3) ENST00000556861


    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat STYX
    8/145 QIAGEN miScript miRNA Assays for microRNAs that regulate STYX (see all 145):
    hsa-miR-106a hsa-miR-3074-3p hsa-miR-519a hsa-miR-4275 hsa-miR-298 hsa-miR-200b hsa-miR-92b hsa-miR-374b*
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    Inhib. RNA
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat STYX
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STYX

    Additional cDNA sequence: 

    AF085865.1 AK098195.1 AK124924.1 AL832591.1 AL832697.1 BC020265.2 BC146995.1 BC146998.1 
    BX647636.1 U87169.1 

    7 DOTS entries:

    DT.310087  DT.407473  DT.91734922  DT.97822819  DT.100750203  DT.100806674  DT.100036140 

    24/100 AceView cDNA sequences (see all 100):

    AK098195 CA437823 CK904386 N44194 H29947 BM800458 BU154927 NM_145251 
    AA761329 AI492892 AA488966 AI243613 U87169 BC020265 BG391583 AA789071 
    CF121970 AA761314 BX646609 BG681149 AA488895 AI742206 BM021057 AL710096 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for STYX    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b
    SP1:                                                                  
    SP2:                                                                  


    ECgene alternative splicing isoforms for STYX

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STYX expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See STYX Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STYX

    SOURCE GeneReport for Unigene cluster: Hs.364980
        SABiosciences Custom PCR Arrays for STYX
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STYX

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for STYX gene from 5/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves STYX1 serine/threonine/tyrosine interacting protein 86.43(n)
    91.96(a)
      423587  XM_421475.3  XP_421475.3 
    lizard
    (Anolis carolinensis)
    Reptilia STYX6
    --
    89(a)
    1 ↔ 1
    GL343527.1(51285-66712)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.254992 Xenopus laevis transcribed sequence with weak similarity more 80.91(n)    CA972273.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570437572   -- 73.47(n)    57043757 
    honey bee
    (Apis mellifera)
    Insecta --
    --
    49(a)
    1 ↔ 1
    Group9.4(1006314-1007585)


    ENSEMBL Gene Tree for STYX (if available)
    TreeFam Gene Tree for STYX (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for STYX gene
    DUSP152  DUSP222  DUSP122  
    4 SIMAP similar genes for STYX using alignment to 1 protein entry:     STYX_HUMAN:
    DUSP8    DUSP22    DUSP19    DUSP9

    STYX for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/693 NCBI SNPs in STYX are shown (see all 693    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs20650501,2
    --33356994(+) cagccG/Tcccaa 2 -- us2k1 tfbs31Minor allele frequency- T:0.50CSA 2
    rs284121201,2
    C,F,--33357017(+) ACAGGG/CGTGAG 2 -- us2k12Minor allele frequency- C:0.50WA CSA 4
    rs799465791,2
    C,F,--33358842(+) AATTTG/TTGGCT 2 -- int11Minor allele frequency- T:0.03NA 120
    rs71483911,2
    C,F,--33359741(+) cctccG/Aaaagt 2 -- int11Minor allele frequency- A:0.03WA 118
    rs784106211,2
    C,--33359772(+) CCACTG/ACACCT 2 -- int12Minor allele frequency- A:0.02NA 122
    rs1117646731,2
    C,--33359895(+) TCTGCC/TTCGGG 2 -- int11Minor allele frequency- T:0.50NA 2
    rs171257161,2
    C,F,H,--33360839(+) ACACAG/AAAGGA 2 -- int114Minor allele frequency- A:0.10NA NS EA WA 1356
    rs766097491,2
    --33361346(+) TTTACG/AGGTTT 2 -- int11Minor allele frequency- A:0.01WA 118
    rs80119371,2
    C,--33361616(+) tccccC/Tccgac 2 -- int11Minor allele frequency- T:0.00NA 2
    rs1132014291,2
    --33362184(+) TGGCCC/TCACCC 2 -- int12Minor allele frequency- T:0.02CSA WA 120

    HapMap Linkage Disequilibrium report for STYX (53196883 - 53241716 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for STYX: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing STYX
    DNA2.0 Custom Variant and Variant Library Synthesis for STYX

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    STYX for disorders           About GeneDecksing

    11 diseases for STYX:    About MalaCards
    type 2 diabetes mellitus    glucose intolerance    diabetes mellitus    cysticercosis
    male infertility    insulinoma    echinococcosis    infertility
    hyperglycemia    lung cancer    arthritis

    1 disease from the University of Copenhagen DISEASES database for STYX:
    Echinococcosis

    4 Novoseek disease relationships for STYX gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    insulinoma 64.1 1 9588444 (1)
    autoimmunity 57 1 19120305 (1)
    diabetes autoimmune 47.6 1 15155543 (1)
    diabetes mellitus insulin-dependent 32.7 2 9389426 (1), 9605631 (1)

    Human Genome Epidemiology (HuGE) Navigator: STYX (1 document)

    Export disorders for STYX gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STYX gene, integrated from 9 sources (see all 42):
    (articles sorted by number of sources associating them with STYX)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A single mutation converts a novel phosphotyrosine binding domain into a dual-specificity phosphatase. (PubMed id 7592916)1, 3, 9 Wishart M.J....Dixon J.E. (1995)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Multiple phosphotyrosine phosphatase mRNAs are expressed in the human lung fibroblast cell line WI-38. (PubMed id 9633825)1, 2 Dayton M.A. and Knobloch T.J. (1997)
    5. Identification of Potentially Damaging Amino Acid Substitutions Leading to Human Male Infertility. (PubMed id 19369647)1 Kuzmin A....Varmuza S. (2009)
    6. Structural genomics of protein phosphatases. (PubMed id 18058037)2 Almo S.C....Burley S.K. (2007)
    7. Non-invasive genetic diagnosis of male infertility using spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization. (PubMed id 17047026)1 Yatsenko A.N....Matzuk M.M. (2006)
    8. The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production. (PubMed id 11842224)1 Wishart M.J. and Dixon J.E. (2002)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Molecular cloning, chromosomal mapping, and developmental expression of a novel protein tyrosine phosphatase-like gene. (PubMed id 10644438)9 Uwanogho D.A.... Sharpe P.T. (1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6815 HGNC: 11447 AceView: STYX Ensembl:ENSG00000198252 euGenes: HUgn6815
    ECgene: STYX H-InvDB: STYX

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for STYX Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
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    Patent Information for STYX gene:
    Search GeneIP for patents involving STYX

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