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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

STXBP6 Gene

protein-coding GIFtS: 50
GCID: GC14M025278

syntaxin binding protein 6 (amisyn)

Explore 1 disease affiliated with
STXBP6 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Syntaxin Binding Protein 6 (Amisyn)¹ ²
Amisyn³
HSPC156¹
Syntaxin-Binding Protein 6²
Amisyn³

External Ids:	HGNC: 19666¹	Entrez Gene: 29091²	Ensembl: ENSG00000168952⁷	OMIM: 607958⁵	UniProtKB: Q8NFX7³

Export aliases for STXBP6 gene to outside databases

Previous GC identifers: GC14M019066 GC14M023268 GC14M023271 GC14M024348 GC14M005395

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for STXBP6:

STXBP6 binds components of the SNARE complex (see MIM 603215) and may be involved in regulating SNARE complex formation

(Scales et al., 2002 (PubMed 12145319)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: STXB6_HUMAN, Q8NFX7

Function: Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional

SNARE complexes and exocytosis

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000014.8 NC_018925.1 NT_026437.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the STXBP6 gene promoter:
ER-alpha NF-E2 p45 Ik-3 Meis-1b Pax-3 SRY Meis-1a ZIC2/Zic2 NF-E2 Meis-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: STXBP6 promoter sequence

Search SABiosciences Chromatin IP Primers for STXBP6

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STXBP6

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q12 Ensembl cytogenetic band: 14q12 HGNC cytogenetic band: 14q11.2

STXBP6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STXBP6 gene location

GeneLoc information about chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14M025278: view genomic region (about GC identifiers)

Start:	25,278,862 bp from pter	End:	25,519,503 bp from pter
Size:	240,642 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: STXB6_HUMAN, Q8NFX7 (See protein sequence)

Recommended Name: Syntaxin-binding protein 6

Size: 210 amino acids; 23554 Da

Subunit: Part of a ternary complex containing SNAP25 and STX1A that can be dissociated by NAPA and NSF. Interacts with

STX4A

Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein

Sequence caution: Sequence=AAM46624.1; Type=Erroneous initiation;

Secondary accessions: D3DS78 Q8N3H1 Q8N8D5 Q96GF3 Q9P008

Alternative splicing: 3 isoforms: Q8NFX7-1 Q8NFX7-2 Q8NFX7-3 (May be due to an intron retention)

Explore the universe of human proteins at neXtProt for STXBP6: NX_Q8NFX7

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8NFX7

STXBP6 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_054897.4

ENSEMBL proteins:

ENSP00000379928 ENSP00000447383 ENSP00000324302 ENSP00000397212 ENSP00000449536

ENSP00000449379 ENSP00000447655 ENSP00000447268 ENSP00000351083

Human Recombinant Protein Products:

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	Novus Biologicals STXBP6 Lysate
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	Uscn Proteins for STXBP6

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0016021	integral to membrane	IEA	--

STXBP6 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for STXBP6

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

STXBP6 for domains About GeneDecksing

1 InterPro domain/family:

IPR001388 Synaptobrevin

Graphical View of Domain Structure for InterPro Entry Q8NFX7

ProtoNet protein and cluster: Q8NFX7

1 Blocks protein family: IPB001388 Synaptobrevin

UniProtKB/Swiss-Prot: STXB6_HUMAN, Q8NFX7

Similarity: Contains 1 v-SNARE coiled-coil homology domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: STXB6_HUMAN, Q8NFX7

Function: Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional

SNARE complexes and exocytosis

miRNA Products:		OriGene 3'-UTR Clone: STXBP6 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat STXBP6
		8 QIAGEN miScript miRNA Assays for microRNAs that regulate STXBP6:
		hsa-miR-34b* hsa-miR-548am hsa-miR-133b hsa-miR-578 hsa-miR-133a hsa-miR-548x hsa-miR-889 hsa-miR-449c

		SwitchGear 3'UTR luciferase reporter plasmid: STXBP6 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STXBP6 (see all 4) OriGene shRNA RFP: STXBP6 OriGene siRNA: STXBP6
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Gene Editing
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STXBP6

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for STXBP6
		Search LifeMap BioReagents cell lines for STXBP6

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STXBP6

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for STXBP6

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for STXBP6 (Q8NFX7³ ENSP00000324302⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
STX4	Q12846³, ENSP00000317714⁴	I2D: score=1 STRING: ENSP00000317714
SNAP25	P60880³, ENSP00000254976⁴	I2D: score=1 STRING: ENSP00000254976
STX1A	Q16623³, ENSP00000222812⁴	I2D: score=1 STRING: ENSP00000222812

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016192	vesicle-mediated transport	IEA	--

STXBP6 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for STXBP6
Search CenterWatch for drugs/clinical trials and news about STXBP6 / STXB6

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for STXBP6 gene:

NM_014178.6

Unigene Cluster for STXBP6:

Syntaxin binding protein 6 (amisyn)

Hs.508958 [show with all ESTs]

Unigene Representative Sequence: AL834346

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000396700 ENST00000548724(uc001wpv.3) ENST00000323944(uc001wpw.3)

ENST00000419632(uc001wpt.3 uc001wpu.3) ENST00000546511 ENST00000550887

ENST00000548369 ENST00000548182(uc001wpx.1) ENST00000358326

miRNA Products:		OriGene 3'-UTR Clone: STXBP6 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat STXBP6
		8 QIAGEN miScript miRNA Assays for microRNAs that regulate STXBP6:
		hsa-miR-34b* hsa-miR-548am hsa-miR-133b hsa-miR-578 hsa-miR-133a hsa-miR-548x hsa-miR-889 hsa-miR-449c

		SwitchGear 3'UTR luciferase reporter plasmid: STXBP6 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STXBP6 (see all 4) OriGene shRNA RFP: STXBP6 OriGene siRNA: STXBP6
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat STXBP6

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for STXBP6 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for STXBP6 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: STXBP6 (NM_014178)
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STXBP6

Additional cDNA sequence:

AF161505.1 AF391153.1 AK096957.1 AK309203.1 AL834346.1 BC009499.2 BC067278.1

8 DOTS entries:

DT.95286519 DT.91756909 DT.100773366 DT.99930467 DT.120760833 DT.120760841 DT.100773365 DT.92041692

24/140 AceView cDNA sequences (see all 140):

AA256850 CA427015 BE292897 BM738712 AA309018 BQ268942 BM353657 BQ024551

BM479164 AI740751 AI131058 AI092142 AW134979 AW517480 BC067278 AI271647

AI190370 R43966 N31108 AW002771 BQ881157 CB069205 AI698322 AA256379

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for STXBP6 About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3	^	4	^	5	^	6a	·	6b	^	7	^	8	^	9	^	10
SP1:							-				-				-										-
SP2:
SP3:									-		-				-										-
SP4:							-		-		-				-

ECgene alternative splicing isoforms for STXBP6

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

STXBP6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AACCATCACC

About this image

STXBP6 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

10 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Spinal Cord

Spinal Dorsal Columns

Dorsal Spinal Cord Progenitor Cells

Spinal Cord

Spinal Ventral Columns

Ventral Spinal Cord Progenitor Cells

Motor Neurons

Brain

Brain

Brain

Mesencephalic Ventricular Zone

Neural Tube

Metencephalon

Neural Tube

Telencephalon

Neural Tube

Spinal Cord

Spinal Dorsal Columns

Spinal Cord

Spinal Ventral Columns

Spinal Cord

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

PureStem™ progenitor SK17 (Embryonic Progenitor Cell)

Epiblast-like cells (Reconstitution of mo...)

See STXBP6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for STXBP6

SOURCE GeneReport for Unigene cluster: Hs.508958

UniProtKB/Swiss-Prot: STXB6_HUMAN, Q8NFX7

Tissue specificity: Detected at low levels in brain, and at very low levels in heart, adrenal gland, testis, liver and

kidney

SABiosciences Custom PCR Arrays for STXBP6

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STXBP6

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for STXBP6 gene from 7/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	STXBP6¹	syntaxin binding protein 6 (amisyn)	85.08(n) 94.29(a)		423299 NM_001199711.1 NP_001186640.1
lizard (Anolis carolinensis)	Reptilia	STXBP6⁶	--	91(a)	1 ↔ 1	1(30018973-30040594)
African clawed frog (Xenopus laevis)	Amphibia	MGC68796²	hypothetical protein MGC68796	76.75(n)		BC060365.1
zebrafish (Danio rerio)	Actinopterygii	stxbp6¹	syntaxin binding protein 6 (amisyn)	70.79(n) 74.76(a)		415153 NM_001002063.1 NP_001002063.1
worm (Caenorhabditis elegans)	Secernentea	sec-3⁶	Exocyst complex component 1	4(a)	1 ↔ 1	X(3095427-3099827)
thale cress (Arabidopsis thaliana)	eudicotyledons	SEC3B⁶ SEC3A⁶	exocyst complex component sec3A	4(a) 4(a)	many ↔ many many ↔ many	1(17466751-17473294) 1(17457122-17464386)
rice (Oryza sativa)	Liliopsida	-- --	roothairless 1, putative, expressed	4(a) 3(a)	many ↔ many many ↔ many	3(23795332-23806523) 11(9789485-9804846)

ENSEMBL Gene Tree for STXBP6 (if available)
TreeFam Gene Tree for STXBP6 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for STXBP6 gene

EXOC1²

1 SIMAP similar gene for STXBP6 using alignment to 2 protein entries: STXB6_HUMAN (see all proteins):

EXOC1

STXBP6 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 14 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs34562160^1,2	C,	--	5396307(+)	`GAGTG-/CCTGTG`	1	--	int¹		0	--	--	--	--
rs71121803^1,2	C,	--	5398298(+)	`CCCAG-/TTTATG`	1	--	int¹		1		NA	2
rs145302510^1,2		--	25280884(+)	`ATAAAC/TAGATA`	1	--	ds500¹		0	--	--	--	--
rs77272061^1,2		--	25281015(+)	`TAAATC/GTACTA`	1	--	ds500¹		0	--	--	--	--
rs190975213^1,2		--	25281103(+)	`ACCAGC/TGACCA`	1	--	ds500¹		0	--	--	--	--
rs200928753^1,2	C,	--	25281166(+)	`TAGGC-/TTTTCT`	1	--	ds500¹		0	--	--	--	--
rs75123368^1,2	C	--	25281171(+)	`TTTTCC/TTTAGG`	1	--	ds500¹		0	--	--	--	--
rs199653909^1,2		--	25281171(+)	`TTTTC-/TTTAGG`	1	--	ds500¹		0	--	--	--	--
rs184012780^1,2		--	25281173(+)	`TTCTTC/TAGGGC`	1	--	ds500¹		0	--	--	--	--
rs2297059^1,2	C,F,H,	--	25281213(+)	`ATAATA/TCCAAG`	1	--	ds500¹		14		EA NA NS WA CSA	824

HapMap Linkage Disequilibrium report for STXBP6 (25278862 - 25519503 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for STXBP6
1 CNV: 66600
1 Indel: 71874

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing STXBP6

DNA2.0 Custom Variant and Variant Library Synthesis for STXBP6

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

STXBP6 for disorders           About GeneDecksing

OMIM gene information: 607958    OMIM disorders: --

1 disease for STXBP6:    About MalaCards

alzheimer's disease

Human Genome Epidemiology (HuGE) Navigator: STXBP6 (1 document)

Export disorders for STXBP6 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for STXBP6 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with STXBP6)

Utopia: connect your pdf to the dynamic
world of online information

Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly. (PubMed id 12145319)^{1, 2, 3} Scales S.J.... Scheller R.H. (2002)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)^{1, 2} Heilig R.... Weissenbach J. (2003)
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{1, 2} Zhang Q.-H.... Chen Z. (2000)
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)¹ Fox C.S....Borecki I.B. (2012)
CD6 and syntaxin binding protein 6 variants and respon se to tumor necrosis factor alpha inhibitors in Danish patients with rheumatoid arthritis. (PubMed id 22685579)¹ Krintel S.B....Hetland M.L. (2012)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Identification of nine novel loci associated with whi te blood cell subtypes in a Japanese population. (PubMed id 21738478)¹ Okada Y....Kamatani N. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
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Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 29091	HGNC: 19666	AceView: STXBP6	Ensembl:ENSG00000168952	euGenes: HUgn29091
ECgene: STXBP6	H-InvDB: STXBP6

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for STXBP6	Pharmacogenomics, SNPs, Pathways

Intellectual Property for STXBP6 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for STXBP6 gene:
Search GeneIP for patents involving STXBP6

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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STXBP6 Gene

syntaxin binding protein 6 (amisyn)

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STXBP6 Gene

syntaxin binding protein 6 (amisyn)

Aliasesfor STXBP6 gene

Summariesfor STXBP6 gene

Genomic Viewsfor STXBP6 gene

Proteinsfor STXBP6 gene

Protein Domains /Familiesfor STXBP6 gene

Functionfor STXBP6 gene

Pathways & Interactionsfor STXBP6 gene

Drugs & Compoundsfor STXBP6 gene

Transcriptsfor STXBP6 gene

Expression for STXBP6 gene

Orthologsfor STXBP6 gene

Paralogsfor STXBP6 gene

Genomic Variantsfor STXBP6 gene

Disorders / Diseasesfor STXBP6 gene

Publicationsfor STXBP6 gene

External Searches for STXBP6 gene

Genome Databases showing STXBP6 gene

Other Databases showing STXBP6 gene

Specialized Databases showing STXBP6 gene

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Productsfor STXBP6 gene

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Aliases
for STXBP6 gene

Summaries
for STXBP6 gene

Genomic Views
for STXBP6 gene

Proteins
for STXBP6 gene

Protein Domains /
Families
for STXBP6 gene

Function
for STXBP6 gene

Pathways & Interactions
for STXBP6 gene

Drugs & Compounds
for STXBP6 gene

Transcripts
for STXBP6 gene

Expression
for STXBP6 gene

Orthologs
for STXBP6 gene

Paralogs
for STXBP6 gene

Genomic Variants
for STXBP6 gene

Disorders / Diseases
for STXBP6 gene

Publications
for STXBP6 gene

Intellectual Property
for STXBP6 gene

Products
for STXBP6 gene