External Ids for STX8 Gene
Previous GeneCards Identifiers for STX8 Gene
The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
GeneCards Summary for STX8 Gene
STX8 (Syntaxin 8) is a Protein Coding gene. Among its related pathways are Delta508-CFTR traffic / ER-to-Golgi in CF and wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF). GO annotations related to this gene include ubiquitin protein ligase binding and SNAP receptor activity.
UniProtKB/Swiss-Prot for STX8 Gene
Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER.