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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STX7 Gene

protein-coding   GIFtS: 61
GCID: GC06M132822

Syntaxin 7

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Syntaxin 71 2
syntaxin-72

External Ids:    HGNC: 114421   Entrez Gene: 84172   Ensembl: ENSG000000799507   OMIM: 6032175   UniProtKB: O154003   

Export aliases for STX7 gene to outside databases

Previous GC identifers: GC06M132404 GC06M132624 GC06M132761 GC06M130353


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for STX7 Gene: 
STX7 (syntaxin 7) is a protein-coding gene. Diseases associated with STX7 include febrile seizures, and schizophrenia, and among its related super-pathways are Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics and Proteolytic cleavage of SNARE complex proteins. GO annotations related to this gene include SNARE binding and SNAP receptor activity. An important paralog of this gene is STX12.

UniProtKB/Swiss-Prot: STX7_HUMAN, O15400
Function: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in
homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late
endosomes and lysosomes

Gene Wiki entry for STX7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_025741.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STX7 gene promoter:
         c-Fos   GR   AP-1   NCX/Ncx   HNF-3beta   PPAR-gamma1   Chx10   c-Jun   PPAR-gamma2   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTX7 promoter sequence
   Search SABiosciences Chromatin IP Primers for STX7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STX7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q23.1   Ensembl cytogenetic band:  6q23.2   HGNC cytogenetic band: 6q23.1

STX7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STX7 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M132822:  view genomic region     (about GC identifiers)

Start:
132,767,006 bp from pter      End:
132,834,337 bp from pter
Size:
67,332 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: STX7_HUMAN, O15400 (See protein sequence)
Recommended Name: Syntaxin-7  
Size: 261 amino acids; 29816 Da
Subunit: Forms a SNARE complex with VTI1B, STX8 and VAMP8 which functions in the homotypic fusion of late
endosomes. Component of the SNARE complex composed of STX7, STX8, VAMP7 and VTI1B that is required for
heterotypic fusion of late endosomes with lysosomes (By similarity). Interacts with VPS11, VPS16 and VPS18.
Interacts with VPS33A
Subcellular location: Early endosome membrane; Single-pass type IV membrane protein (By similarity)
Secondary accessions: E1P579 Q5SZW2 Q96ES9
Alternative splicing: 2 isoforms:  O15400-1   O15400-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for STX7: NX_O15400

Explore proteomics data for STX7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O15400

  • STX7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    STX7 Protein Expression
    REFSEQ proteins: NP_003560.2  
    ENSEMBL proteins: 
     ENSP00000356918   ENSP00000356914  
    Reactome Protein details: O15400
    Human Recombinant Protein Products for STX7: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Sino Biological Recombinant Protein for STX7
    Sino Biological Cell Lysate for STX7 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for STX7 

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005765lysosomal membrane IDA17897319
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--
    GO:0031201SNARE complex IBA--
    GO:0031901early endosome membrane IEA--

    STX7 for ontologies           About GeneDecksing



    STX7 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR000727 T_SNARE_dom
     IPR010989 t-SNARE
     IPR006011 Syntaxin_N
     IPR006012 Syntaxin/epimorphin_CS

    Graphical View of Domain Structure for InterPro Entry O15400

    ProtoNet protein and cluster: O15400

    1 Blocks protein domain: IPB006011 Syntaxin

    UniProtKB/Swiss-Prot: STX7_HUMAN, O15400
    Similarity: Belongs to the syntaxin family
    Similarity: Contains 1 t-SNARE coiled-coil homology domain


    STX7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: STX7_HUMAN, O15400
    Function: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in
    homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late
    endosomes and lysosomes

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000149SNARE binding IBA--
    GO:0005484SNAP receptor activity IBA--
    GO:0005515protein binding ----
         
    STX7 for ontologies           About GeneDecksing


    Animal Models:
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for STX7 
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    miRNA
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    miRTarBase miRNAs that target STX7:
    hsa-mir-192 (MIRT004164), hsa-mir-30a (MIRT005199)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat STX7
    8/52 QIAGEN miScript miRNA Assays for microRNAs that regulate STX7 (see all 52):
    hsa-miR-548j hsa-miR-3685 hsa-miR-128 hsa-miR-301a hsa-miR-488 hsa-miR-548l hsa-miR-10b* hsa-miR-508-5p
    SwitchGear 3'UTR luciferase reporter plasmidSTX7 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for STX7 About   (see all 6)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics
    Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics0.44
    SNARE interactions in vesicular transport0.40
    2Botulinum neurotoxicity
    Botulinum neurotoxicity0.89
    Proteolytic cleavage of SNARE complex proteins0.89
    3Transmission across Chemical Synapses
    Neuronal System0.67
    4Clathrin-dependent protein traffic
    Transport Clathrin-coated vesicle cycle0.66
    5Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for STX7
        Transport Clathrin-coated vesicle cycle


    4        Reactome Pathways for STX7
        Proteolytic cleavage of SNARE complex proteins
    Botulinum neurotoxicity
    Neuronal System
    Disease

    1 PharmGKB Pathway for STX7
        Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics

    2         Kegg Pathways  (Kegg details for STX7):
        SNARE interactions in vesicular transport
    Phagosome


    STX7 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for STX7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/53 Interacting proteins for STX7 (O154002, 3 ENSP000003569184) via UniProtKB, MINT, STRING, and/or I2D (see all 53)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STX8Q9UNK02, 3, ENSP000003052554MINT-7255483 MINT-7255586 MINT-7255636 MINT-7255549 MINT-7255609 I2D: score=3 STRING: ENSP00000305255
    VAMP7P518092, 3, ENSP000002864484MINT-7255549 I2D: score=2 STRING: ENSP00000286448
    MAPK6Q166592, 3MINT-8262066 I2D: score=2 
    STX6O437522, 3, ENSP000002583014MINT-7255483 MINT-7255586 MINT-7255636 MINT-7255549 MINT-7255609 I2D: score=3 STRING: ENSP00000258301
    VAMP8Q9BV402, 3, ENSP000002638644MINT-7255609 I2D: score=3 STRING: ENSP00000263864
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006886intracellular protein transport IBA--
    GO:0006892post-Golgi vesicle-mediated transport TAS9358037
    GO:0016079synaptic vesicle exocytosis IBA--
    GO:0016192vesicle-mediated transport ----

    STX7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STX7

    Search CenterWatch for drugs/clinical trials and news about STX7

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for STX7 gene: 
    NM_003569.2  

    Unigene Cluster for STX7:

    Syntaxin 7
    Hs.593148  [show with all ESTs]
    Unigene Representative Sequence: NM_003569
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367941(uc003qdg.2 uc011ecg.1 uc011ech.1) ENST00000367937
    ENST00000448348 ENST00000475879
    miRNA
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    8/52 QIAGEN miScript miRNA Assays for microRNAs that regulate STX7 (see all 52):
    hsa-miR-548j hsa-miR-3685 hsa-miR-128 hsa-miR-301a hsa-miR-488 hsa-miR-548l hsa-miR-10b* hsa-miR-508-5p
    SwitchGear 3'UTR luciferase reporter plasmidSTX7 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat STX7
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat STX7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STX7

    Additional mRNA sequence: 

    AF131808.1 AJ420529.1 AK294911.1 AK301464.1 BC011975.1 U77942.1 

    18 DOTS entries:

    DT.95208535  DT.215965  DT.100814407  DT.101984526  DT.121387057  DT.100716316  DT.121387077  DT.121387090 
    DT.100814406  DT.40132581  DT.92014308  DT.99940584  DT.100814400  DT.92005992  DT.92433166  DT.95208538 
    DT.95208542  DT.40132582 

    24/390 AceView cDNA sequences (see all 390):

    BM554109 BM468724 AI476006 BU070297 BQ440266 AI969408 AI086299 AI290215 
    AL543305 AA830963 AI805300 AA283071 AU127071 AI866843 AA830303 BF061113 
    AI636831 AI866913 AA314343 BM723998 AW300480 CR618907 AI341494 AL600868 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STX7 expression in normal human tissues (normalized intensities)      STX7 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGAAAAAAT
    STX7 Expression
    About this image


    STX7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             ganglion/cranial/facial VII   
     
     Peripheral Nervous System (Nervous System)
             spinal/ganglion/dorsal root ganglion   
     
     Spinal Cord (Nervous System)
             spinal/ganglion/dorsal root ganglion   
     
     Eye (Sensory Organs)
             Retina

    See STX7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STX7

    SOURCE GeneReport for Unigene cluster: Hs.593148

    UniProtKB/Swiss-Prot: STX7_HUMAN, O15400
    Tissue specificity: Highest expression is found in placenta followed by heart, skeletal muscle, kidney and brain.
    Low expression is found in pancreas, lung and liver

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STX7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for STX7 gene from 10/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Stx71 , 5 syntaxin 71, 5 87.64(n)1
    94.98(a)1
      10 (11.45 cM)5
    533311  NM_016797.41  NP_058077.21 
     241493175 
    chicken
    (Gallus gallus)
    Aves STX71 syntaxin 7 79.97(n)
    82.21(a)
      426930  NM_001012943.1  NP_001012961.1 
    lizard
    (Anolis carolinensis)
    Reptilia STX76
    Uncharacterized protein
    78(a)
    1 ↔ 1
    GL343200.1(4505253-4532948)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC531612 similar to syntaxin 7 73.84(n)    BC046851.1 
    zebrafish
    (Danio rerio)
    Actinopterygii stx7l1 syntaxin 7-like 61.65(n)
    60.16(a)
      562669  XM_003200760.1  XP_003200808.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Syx71 Syntaxin 7 49.52(n)
    43.98(a)
      36173  NM_168906.1  NP_730633.1 
    worm
    (Caenorhabditis elegans)
    Secernentea syx-76
    Protein SYX-7
    28(a)
    1 → many
    I(9001911-9003965)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PEP121 Pep12p 45.88(n)
    27.32(a)
      854201   NP_014679.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SYP231 syntaxin-23 47.39(n)
    33.48(a)
      827494  NM_001084934.1  NP_001078403.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g02549001 hypothetical protein 42.86(n)
    33.06(a)
      4327713  NM_001049155.1  NP_001042620.1 


    ENSEMBL Gene Tree for STX7 (if available)
    TreeFam Gene Tree for STX7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for STX7 gene
    STX122  TSNARE12  
    2 SIMAP similar genes for STX7 using alignment to 1 protein entry:     STX7_HUMAN:
    STX12    TSNARE1

    STX7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1282 SNPs in STX7 are shown (see all 1282)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1895442751,2
    --132778202(+) AACAGC/TACAGC 1 -- ds50010--------
    rs1427451261,2
    --132778214(+) TTCTGC/GATGTT 1 -- ds50010--------
    rs1814127421,2
    --132778220(+) ATGTTC/TTCAAG 1 -- ds50010--------
    rs37347461,2
    C,F--132778348(+) TCCATC/GAAGTG 1 -- ds50010--------
    rs65697981,2
    C,F,H--132778538(+) TATCTC/TTCATG 1 -- ds500117Minor allele frequency- T:0.28NA NS EA WA CSA 932
    rs1380886261,2
    --132778588(+) AAAAAA/CTGGTT 1 -- ds50010--------
    rs1895449751,2
    C--132778664(+) TACACC/TGTAAC 1 -- ut310--------
    rs753203091,2
    C,F--132778685(+) TCCCAT/CTGGTT 1 -- ut312Minor allele frequency- C:0.15CSA WA 120
    rs1417943291,2
    C--132778700(+) ATTTGA/GTAAGT 1 -- ut310--------
    rs1818217551,2
    --132778869(+) TCATAC/TTTAAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for STX7 (132767006 - 132834337 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for STX7:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv819019CNV Loss19587683
    nsv830811CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603217    OMIM disorders: --

    4 diseases for STX7:    About MalaCards
    febrile seizures    schizophrenia    melanoma    neuronitis


    STX7 for disorders           About GeneDecksing

    Genetic Association Database (GAD): STX7
    Human Genome Epidemiology (HuGE) Navigator: STX7 (1 document)

    Export disorders for STX7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STX7 gene, integrated from 9 sources (see all 66):
    (articles sorted by number of sources associating them with STX7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human syntaxin 7: a Pep12p/Vps6p homologue implicated in vesicle trafficking to lysosomes. (PubMed id 9358037)1, 2, 3, 9 Wang H.... Pevsner J. (1997)
    2. Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking. (PubMed id 10564279)1, 2, 9 Prekeris R.... Scheller R.H. (1999)
    3. Molecular characterization of mammalian homologues of class c Vps proteins that interact with syntaxin-7. (PubMed id 11382755)1, 2, 9 Kim B.Y....Akazawa C. (2001)
    4. No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics. (PubMed id 18198266)1, 4 Sanders A.R....Gejman P.V. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
    7. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    8. Syntaxin 7 mediates endocytic trafficking to late endosomes. (PubMed id 10692457)1, 2 Nakamura N.... Futai M. (2000)
    9. Syntaxin 7, a novel syntaxin member associated with the early endosomal compartment. (PubMed id 9417091)1, 9 Wong S.H....Hong W. (1998)
    10. Intracellular location of syntaxin 7 in human neutrop hils. (PubMed id 20170677)1, 9 Xie L.X....Mollinedo F. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8417 HGNC: 11442 AceView: STX7 Ensembl:ENSG00000079950 euGenes: HUgn8417
    ECgene: STX7 Kegg: 8417 H-InvDB: STX7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for STX7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for STX7 gene:
    Search GeneIP for patents involving STX7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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