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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STX6 Gene

protein-coding   GIFtS: 59
GCID: GC01M180941

syntaxin 6

 Explore 15 diseases affiliated with
STX6 via our new
 Human Malady Compendium 
Biological research products
for STX6
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Syntaxin 61 2
Syntaxin-61

External Ids:    HGNC: 114411   Entrez Gene: 102282   Ensembl: ENSG000001358237   OMIM: 6039445   UniProtKB: O437523   

Export aliases for STX6 gene to outside databases

Previous GC identifers: GC01M178439 GC01M176341 GC01M177433 GC01M178152 GC01M178177 GC01M177644 GC01M179179 GC01M179208 GC01M152173


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: STX6_HUMAN, O43752
Function: Involved in intracellular vesicle trafficking

Gene Wiki entry for STX6


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STX6 gene promoter:
         RFX1   ISGF-3   Elk-1   AML1a   FOXL1   GATA-1   Roaz   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTX6 promoter sequence
   Search SABiosciences Chromatin IP Primers for STX6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STX6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q25.3   Ensembl cytogenetic band:  1q25.3   HGNC cytogenetic band: 1q25.3

STX6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STX6 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M180941:  view genomic region     (about GC identifiers)

Start:
180,941,861 bp from pter      End:
180,992,047 bp from pter
Size:
50,187 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: STX6_HUMAN, O43752 (See protein sequence)
Recommended Name: Syntaxin-6  
Size: 255 amino acids; 29176 Da
Subunit: Binds EEA1. Interacts with VPS45A. Interacts with MARCH2 and MARCH3 (By similarity). Interacts with GOPC.
Identified in a complex containing STX6, STX12, VAMP4 and VTI1A
Subcellular location: Golgi apparatus membrane; Single-pass type IV membrane protein (Potential)
1 PDB 3D structure from and Proteopedia for STX6:
2NPS (3D)    
Secondary accessions: B2R652 Q5VY08 Q6FH83

Explore the universe of human proteins at neXtProt for STX6: NX_O43752

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O43752

  • STX6 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005810.1  
    ENSEMBL proteins: 
     ENSP00000258301   ENSP00000440188  
    Reactome Protein details: O43752
    Human Recombinant Protein Products: 
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    Novus Biologicals STX6 Protein
    Novus Biologicals STX6 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for STX6

    Gene Ontology (GO): 5/11 cellular component terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005624membrane fraction ----
    GO:0005769early endosome IDA10506127
    GO:0005794Golgi apparatus IDA19224922
    GO:0005802trans-Golgi network ----


    STX6 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    STX6 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR000727 T_SNARE_dom
     IPR010989 t-SNARE
     IPR015260 Syntaxin-6_N
     IPR006012 Syntaxin/epimorphin_CS

    Graphical View of Domain Structure for InterPro Entry O43752

    ProtoNet protein and cluster: O43752

    UniProtKB/Swiss-Prot: STX6_HUMAN, O43752
    Similarity: Belongs to the syntaxin family
    Similarity: Contains 1 t-SNARE coiled-coil homology domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: STX6_HUMAN, O43752
    Function: Involved in intracellular vesicle trafficking

    miRNA
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    hsa-miR-188-5p hsa-miR-106a hsa-miR-938 hsa-miR-30d hsa-miR-519a hsa-miR-1304 hsa-miR-30a hsa-miR-149
    SwitchGear 3'UTR luciferase reporter plasmidSTX6 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STX6 (see all 7)
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005484SNAP receptor activity IEA--
    GO:0005515protein binding IPI--


    STX6 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Botulinum neurotoxicity
    Botulinum neurotoxicity1.00
    Proteolytic cleavage of SNARE complex proteins0.89
    2Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics
    Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics1.00
    SNARE interactions in vesicular transport0.40
    3Clathrin-dependent protein traffic
    Transport_Clathrin-coated vesicle cycle0.66
    wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)0.37
    4COPII (Coat Protein 2) Mediated Vesicle Transport
    Normal wtCFTR traffic / ER-to-Golgi 0.36
    Delta508-CFTR traffic / ER-to-Golgi in CF0.36
    5Cytoskeletal Signaling
    Cytoskeletal Signaling1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for STX6
        Cytoskeletal Signaling

    4 GeneGo (Thomson Reuters) Pathways for STX6
        wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)
    Delta508-CFTR traffic / ER-to-Golgi in CF
    Normal wtCFTR traffic / ER-to-Golgi
    Transport Clathrin-coated vesicle cycle

    4        Reactome Pathways for STX6
        Proteolytic cleavage of SNARE complex proteins
    Botulinum neurotoxicity
    Neuronal System
    Disease

    1 PharmGKB Pathway for STX6
        Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics

    1         Kegg Pathway  (Kegg details for STX6):
        SNARE interactions in vesicular transport


    STX6 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for STX6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/32 Interacting proteins for STX6 (O437522, 3 ENSP000002583014) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    VAMP3Q158362, 3, ENSP000000546664MINT-7255586 MINT-7255636 I2D: score=1 STRING: ENSP00000054666
    VAMP4O753792, 3, ENSP000002361924MINT-7255483 MINT-4052274 MINT-4052302 MINT-4052327 MINT-4052351 I2D: score=3 STRING: ENSP00000236192
    STX7O154002, 3, ENSP000003569184MINT-7255483 MINT-7255586 MINT-7255636 MINT-7255549 MINT-7255609 I2D: score=3 STRING: ENSP00000356918
    VTI1AQ96AJ92, 3, ENSP000003767924MINT-4052274 MINT-4052302 MINT-4052327 MINT-4052351 I2D: score=1 STRING: ENSP00000376792
    STX8Q9UNK02, ENSP000003052554MINT-7255483 MINT-7255586 MINT-7255636 MINT-7255549 MINT-7255609 STRING: ENSP00000305255
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006886intracellular protein transport IEA--
    GO:0006906vesicle fusion IPI10506127
    GO:0007032endosome organization IEA--
    GO:0016192vesicle-mediated transport ----
    GO:0042147retrograde transport, endosome to Golgi IMP19224922


    STX6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    STX6 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STX6
    5 Novoseek chemical compound relationships for STX6 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    mannose 6-phosphate 65.8 2 10594043 (1), 20163565 (1)
    n-ethylmaleimide 33.4 2 16154903 (1), 16565709 (1)
    phosphatidylinositol 9.09 2 12911814 (1), 12702770 (1)
    glucose 0 1 12857877 (1)
    calcium 0 2 19063970 (1)

    Search CenterWatch for drugs/clinical trials and news about STX6 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for STX6 gene: 
    NM_005819.4  

    Unigene Clusters for STX6:

    Syntaxin 6
    Hs.518417  [show with all ESTs], Hs.737037  [show with all ESTs]
    Unigene Representative Sequences: NM_005819, AK056657
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000258301(uc021pfr.1 uc010pnr.2) ENST00000469135 ENST00000496476
    ENST00000542060

    miRNA
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    8/76 QIAGEN miScript miRNA Assays for microRNAs that regulate STX6 (see all 76):
    hsa-miR-188-5p hsa-miR-106a hsa-miR-938 hsa-miR-30d hsa-miR-519a hsa-miR-1304 hsa-miR-30a hsa-miR-149
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    Additional cDNA sequence: AK056657.1 

    10 DOTS entries:

    DT.40287936  DT.452088  DT.91761266  DT.100681426  DT.100750102  DT.121378171  DT.97822919  DT.432087 
    DT.100782052  DT.95163330 

    24/159 AceView cDNA sequences (see all 159):

    Z40225 BU633621 BX280773 BQ225769 CR612118 AI073357 CR591752 AA620939 
    CN483917 AW008580 Z42051 BC039118 BU687412 AI083723 BF513194 AL556927 
    AA653116 F10757 AI651124 BC009944 AA337908 BF589090 F13155 BU179596 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for STX6    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11
    SP1:                    -                       -                                                         
    SP2:                          -                                                                           
    SP3:                                                                                                      
    SP4:                                                                          -     -     -     -         
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for STX6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STX6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See STX6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STX6

    SOURCE GeneReport for Unigene clusters: Hs.518417 Hs.737037
        SABiosciences Custom PCR Arrays for STX6
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STX6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for STX6 gene from 9/34 species (see all 34)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves STX61 syntaxin 6 81.23(n)
    91.73(a)
      424413  NM_001006531.1  NP_001006531.1 
    lizard
    (Anolis carolinensis)
    Reptilia STX66
    --
    89(a)
    1 ↔ 1
    4(69841888-69858802)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.27932 Xenopus laevis transcribed sequence with moderate similarity to protein refNP_005810.1 (H.sapiens) syntaxin 6 [Homo sapiens] less 77.22(n)    CD254312.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.117342 Transcribed sequence with moderate similarity to protein refNP_005810.1 (H.sapiens) syntaxin 6 [Homo sapiens] less 75.36(n)    57048443 
    fruit fly
    (Drosophila melanogaster)
    Insecta Syx61 Syntaxin 6 57.6(n)
    54.4(a)
      40373  NM_206092.1  NP_995814.1 
    worm
    (Caenorhabditis elegans)
    Secernentea syx-66
    Putative syntaxin C15C7.1
    38(a)
    1 → many
    X(3164513-3165646)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TLG11 Tlg1p 40.81(n)
    24.77(a)
      852079   NP_010756.3 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SYP611 syntaxin-61 45.71(n)
    29.11(a)
      839749  NM_102617.3  NP_564310.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g09633001 hypothetical protein 46(n)
    34.93(a)
      4324558  NM_001052020.1  NP_001045485.1 


    ENSEMBL Gene Tree for STX6 (if available)
    TreeFam Gene Tree for STX6 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for STX6 gene
    STX102  
    1 SIMAP similar gene for STX6 using alignment to 2 protein entries:     STX6_HUMAN (see all proteins):
    STX10

    STX6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/889 NCBI SNPs in STX6 are shown (see all 889    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1163367831,2
    C,F,--180941684(+) ACATGC/GAGTTA 1 -- int12Minor allele frequency- G:0.01WA EU 687
    rs1864286271,2
    --180941848(+) AGTCCG/TTTTCA 1 -- int10--------
    rs778648721,2
    C,F,--180941906(+) TGTACA/GTACTG 1 -- int11Minor allele frequency- G:0.11WA 118
    rs1416149141,2
    --180942123(+) GCGGAC/TTTTGC 1 -- int10--------
    rs1382358471,2
    --180942167(+) AGTCCG/TGTAAC 1 -- int10--------
    rs1907811311,2
    --180942371(+) CAGTAA/CAAGGT 1 -- ut310--------
    rs1829201641,2
    --180942477(+) TAACAA/GGGAAC 1 -- ut310--------
    rs1495625171,2
    --180942547(+) CTACCA/GTCTCT 1 -- ut310--------
    rs1442564731,2
    --180942569(+) GTAAAA/TCACTT 1 -- ut310--------
    rs768386361,2
    --180942579(+) TAACAC/GAGACA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for STX6 (180941861 - 180992047 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for STX6: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    STX6 for disorders           About GeneDecksing

    OMIM gene information: 603944    OMIM disorders: --

    15 diseases for STX6:    About MalaCards
    supranuclear palsy    progressive supranuclear palsy    chronic myeloid leukemia    myeloid leukemia
    tauopathy    cystic fibrosis    fibrosis    tuberculosis
    leukemia    melanoma    pancreatitis    hepatitis
    malaria    neuronitis    mycobacterium tuberculosis

    1 disease from the University of Copenhagen DISEASES database for STX6:
    Progressive supranuclear palsy

    1 Novoseek disease relationship for STX6 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tuberculosis 0 1 12702770 (1)


    Export disorders for STX6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STX6 gene, integrated from 9 sources (see all 87):
    (articles sorted by number of sources associating them with STX6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Co-expression of several human syntaxin genes in neutrophils and differentiating HL-60 cells: variant isoforms and detection of syntaxin 1. (PubMed id 10080545)1, 2, 3 Martin-Martin B.... Mollinedo F. (1999)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6. (PubMed id 11384996)1, 2 Charest A.... Housman D.E. (2001)
    6. Involvement of SNAP-23 and syntaxin 6 in human neutrophil exocytosis. (PubMed id 11001914)1, 9 Martin-Martin B....Mollinedo F. (2000)
    7. The Rab5 effector EEA1 interacts directly with syntaxin-6. (PubMed id 10506127)1, 9 Simonsen A.... Stenmark H. (1999)
    8. MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking. (PubMed id 15689499)1, 9 Nakamura N.... Hirose S. (2005)
    9. A new syntaxin family member implicated in targeting of intracellular transport vesicles. (PubMed id 8663448)1, 9 Bock J.B....Scheller R.H. (1996)
    10. Syntaxin 6, a regulator of the protein trafficking machinery and a target of the p53 family, is required for cell adhesion and survival. (PubMed id 18779328)1, 9 Zhang Y....Chen X. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10228 HGNC: 11441 AceView: STX6 Ensembl:ENSG00000135823 euGenes: HUgn10228
    ECgene: STX6 Kegg: 10228 H-InvDB: STX6

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for STX6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for STX6 gene:
    Search GeneIP for patents involving STX6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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