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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STX5 Gene

protein-coding   GIFtS: 59
GCID: GC11M062574

syntaxin 5

(Previous name: syntaxin 5A )
(Previous symbol: STX5A)
 Explore 8 diseases affiliated with
STX5 via our new
 Human Malady Compendium 
Biological research products
for STX5
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Syntaxin 51 2
STX5A1 2 3 5
SED51 2
Syntaxin 5A1 2
Syntaxin-51

External Ids:    HGNC: 114401   Entrez Gene: 68112   Ensembl: ENSG000001622367   OMIM: 6031895   UniProtKB: Q131903   

Export aliases for STX5 gene to outside databases

Previous GC identifers: GC11M062331 GC11M058904


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for STX5:
This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell
membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking
and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in
autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively
spliced transcript variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, Sep
2011)

UniProtKB/Swiss-Prot: STX5_HUMAN, Q13190
Function: Mediates endoplasmic reticulum to Golgi transport (By similarity)

Gene Wiki entry for STX5


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STX5 gene promoter:
         AP-1   ATF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTX5 promoter sequence
   Search SABiosciences Chromatin IP Primers for STX5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STX5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12.3   Ensembl cytogenetic band:  11q12.3   HGNC cytogenetic band: 11q12.3

STX5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STX5 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M062574:  view genomic region     (about GC identifiers)

Start:
62,574,369 bp from pter      End:
62,599,560 bp from pter
Size:
25,192 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: STX5_HUMAN, Q13190 (See protein sequence)
Recommended Name: Syntaxin-5  
Size: 355 amino acids; 39673 Da
Subunit: Part of a ternary complex containing STX5A, NSFL1C and VCP. Identified in a unique SNARE complex composed of
the Golgi SNAREs GOSR1, GOSR2, YKT6 and VTI1A (By similarity). Interacts with COG4
Subcellular location: Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type IV membrane
protein (By similarity). Golgi apparatus membrane; Single-pass type IV membrane protein (By similarity)
1 PDB 3D structure from and Proteopedia for STX5:
3EFO (3D)    
Secondary accessions: B2R8T2 Q5U0D4 Q7Z3T6 Q9BUG1
Alternative splicing, Alternative initiation: 3 isoforms:  Q13190-1   Q13190-2   Q13190-3   (Produced by alternative splicing and alternative initiation)

Explore the universe of human proteins at neXtProt for STX5: NX_Q13190

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13190

  • STX5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001231595.1  NP_003155.2  

    ENSEMBL proteins: 
     ENSP00000367129   ENSP00000294179   ENSP00000378182   ENSP00000434107   ENSP00000432748  
     ENSP00000414289   ENSP00000435973   ENSP00000436495   ENSP00000441428  
    Reactome Protein details: Q13190
    Human Recombinant Protein Products: 
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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for STX5

    Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005783endoplasmic reticulum IEA--
    GO:0005794Golgi apparatus IDA--


    STX5 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    STX5 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR000727 T_SNARE_dom
     IPR010989 t-SNARE
     IPR006011 Syntaxin_N
     IPR006012 Syntaxin/epimorphin_CS

    Graphical View of Domain Structure for InterPro Entry Q13190

    ProtoNet protein and cluster: Q13190

    1 Blocks protein family: IPB006011 Syntaxin

    UniProtKB/Swiss-Prot: STX5_HUMAN, Q13190
    Similarity: Belongs to the syntaxin family
    Similarity: Contains 1 t-SNARE coiled-coil homology domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: STX5_HUMAN, Q13190
    Function: Mediates endoplasmic reticulum to Golgi transport (By similarity)

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidSTX5 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005484SNAP receptor activity IDA15215310
    GO:0047485protein N-terminus binding IPI19536132


    STX5 for ontologies           About GeneDecksing


    8 GenomeRNAi human phenotypes for STX5:
     Decreased Salmonella enterica   Decreased Salmonella enterica   Decreased Salmonella enterica   Decreased Salmonella enterica  
     Decreased Salmonella-containin  Decreased Tat-dependent transc  Decreased p24 protein expressi  Increased cell death HMECs cel 

    Animal Models:
         1 MGI phenotypic allele for Stx5a (no phenotypes)

    STX5 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Botulinum neurotoxicity
    Botulinum neurotoxicity1.00
    Proteolytic cleavage of SNARE complex proteins0.89
    2Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics
    Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics1.00
    SNARE interactions in vesicular transport0.40
    3Disease
    Disease1.00
    4Transmission across Chemical Synapses
    Neuronal System0.67
    5Clathrin-dependent protein traffic
    Transport_Clathrin-coated vesicle cycle0.66

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for STX5
        Transport Clathrin-coated vesicle cycle

    4        Reactome Pathways for STX5
        Proteolytic cleavage of SNARE complex proteins
    Botulinum neurotoxicity
    Neuronal System
    Disease

    1 PharmGKB Pathway for STX5
        Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics

    1         Kegg Pathway  (Kegg details for STX5):
        SNARE interactions in vesicular transport


    STX5 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for STX5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/103 Interacting proteins for STX5 (Q131902, 3 ENSP000002941794) via UniProtKB, MINT, STRING, and/or I2D (see all 103)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COG4Q9H9E32, 3, ENSP000003157754MINT-7296969 MINT-7296916 I2D: score=1 STRING: ENSP00000315775
    APLP1P516932, 3MINT-64120 I2D: score=5 
    BAG6P463792, 3MINT-64124 I2D: score=5 
    COPS6Q7L5N12, 3MINT-64123 I2D: score=5 
    IMMTQ168912, 3MINT-64122 I2D: score=5 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006886intracellular protein transport IEA--
    GO:0006888ER to Golgi vesicle-mediated transport IEA--
    GO:0006903vesicle targeting TAS9188044
    GO:0016192vesicle-mediated transport ----
    GO:0042147retrograde transport, endosome to Golgi IDA15215310


    STX5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    STX5 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STX5
    1 Novoseek chemical compound relationship for STX5 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    atp 0 3 9325254 (2)

    Search CenterWatch for drugs/clinical trials and news about STX5 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for STX5 gene (2 alternative transcripts): 
    NM_001244666.1  NM_003164.4  

    Unigene Cluster for STX5:

    Syntaxin 5
    Hs.654602  [show with all ESTs]
    Unigene Representative Sequence: NM_001244666
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377897 ENST00000294179(uc001nvh.3 uc010rmj.2 uc010rmi.2)
    ENST00000394690 ENST00000492066 ENST00000491231 ENST00000431400 ENST00000488303
    ENST00000486437 ENST00000541317

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    hsa-miR-485-5p hsa-miR-3660 hsa-miR-513a-5p hsa-miR-1271 hsa-miR-431 hsa-miR-629* hsa-miR-133a hsa-miR-24
    SwitchGear 3'UTR luciferase reporter plasmidSTX5 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STX5

    Additional cDNA sequence: 

    AK296675.1 AK313497.1 BC002645.1 BC012137.1 BT019646.1 BT019647.1 BX537426.1 U26648.1 

    16 DOTS entries:

    DT.100810907  DT.100810899  DT.447467  DT.97848001  DT.97820918  DT.87005608  DT.100842665  DT.95341911 
    DT.95254928  DT.120734005  DT.91888121  DT.95254925  DT.100705633  DT.100810897  DT.75172632  DT.97848002 

    24/444 AceView cDNA sequences (see all 444):

    BQ944616 BM562596 BU542585 BM676013 AW262886 AA278855 BQ936549 BX282232 
    CB051156 CA394518 BX508267 CR590126 BI757263 BF036489 BQ218604 BM920243 
    AA748437 BM997074 CA487275 BU502466 BM831929 CR618779 BE882020 AA341178 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for STX5 (see all 6)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11a · 11b · 11c
    SP1:                                                              -           -                                 
    SP2:                                                              -           -                 -               
    SP3:                                                                                                            
    SP4:                                                                                            -               
    SP5:                                                                          -                                 


    ECgene alternative splicing isoforms for STX5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STX5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGAGGCAGGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See STX5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STX5

    SOURCE GeneReport for Unigene cluster: Hs.654602
        SABiosciences Custom PCR Arrays for STX5
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STX5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for STX5 gene from 9/32 species (see all 32)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Stx5a1 , 5 syntaxin 5A1, 5 89.86(n)1
    94.08(a)1
      19 (5.45 cM)5
    563891  NM_001167799.11  NP_001161271.11 
     87414135 
    lizard
    (Anolis carolinensis)
    Reptilia STX56
    --
    76(a)
    1 ↔ 1
    GL343739.1(174552-192022)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.141902 Xenopus laevis transcribed sequence with moderate similarity more 79.88(n)    CA790267.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb81g122 wufb81g12 77.76(n)   323105  BC059605.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Syx51 Syntaxin 5 56.43(n)
    54.82(a)
      34966  NM_078858.4  NP_523582.4 
    worm
    (Caenorhabditis elegans)
    Secernentea syx-51 Protein SYX-5 49.05(n)
    44.11(a)
      179611  NM_073567.5  NP_505968.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SED5(YLR026C)4
    SED51
    cis-Golgi t-SNARE syntaxin required for vesicular transport more4
    Sed5p1
    44.11(n)1
    35.69(a)1
      12(196472-195450)4
    8507131, 4  NP_013126.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SYP321 syntaxin-32 49.56(n)
    42.67(a)
      822024  NM_113342.3  NP_189078.2 
    rice
    (Oryza sativa)
    Liliopsida Os01g01792001 hypothetical protein 48.8(n)
    42.81(a)
      4323876  NM_001048732.1  NP_001042197.1 


    ENSEMBL Gene Tree for STX5 (if available)
    TreeFam Gene Tree for STX5 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/459 NCBI SNPs in STX5 are shown (see all 459    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs122253381,2
    C,H,--58902961(+) TTGGTG/AAAGTG 2 -- ds50014Minor allele frequency- A:0.00NS EA 420
    rs112312241,2
    C,F,H--58902992(+) TCAACT/GGGAGT 2 -- ds50014Minor allele frequency- G:0.00NS EA 416
    rs1149763291,2
    C,--58903606(+) GTAAGG/AGCATC 2 -- ut311Minor allele frequency- A:0.01WA 118
    rs104841,2
    C,--58903614(-) AGGGAG/TATGAT 2 -- ut31 ese32Minor allele frequency- T:0.00MN NA 186
    rs176441,2
    C--58903632(+) CAACGC/TTTCCT 2 -- ut311Minor allele frequency- T:0.00MN 184
    rs115578251,2
    C,H--58903763(-) TGAAAC/TACACA 2 -- ut31 ese32Minor allele frequency- T:0.01NS NA 182
    rs122922811,2
    C,F,H,--58904250(+) TTTGTG/ATATAG 2 -- int110Minor allele frequency- A:0.08NS EA NA WA 1208
    rs27300331,2
    C,--58905982(+) TCCTGG/ACTAAC 2 -- int11Minor allele frequency- A:0.50WA 2
    rs116032031,2
    H--58906130(+) atcgcA/Cccatt 2 -- int10--------
    rs29582351,2
    H--58906208(+) AAGACA/TTTATG 2 -- int14Minor allele frequency- T:0.00NS EA 412

    HapMap Linkage Disequilibrium report for STX5 (62574369 - 62599560 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for STX5
         1 CNV: 0150

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    STX5 for disorders           About GeneDecksing

    OMIM gene information: 603189    OMIM disorders: --

    8 diseases for STX5:    About MalaCards
    endometriosis    intrahepatic cholangiocarcinoma    cystic fibrosis    stomatitis
    cholangiocarcinoma    fibrosis    malaria    neuronitis

    Human Genome Epidemiology (HuGE) Navigator: STX5 (1 document)

    Export disorders for STX5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STX5 gene, integrated from 9 sources (see all 64):
    (articles sorted by number of sources associating them with STX5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and identification of human syntaxin 5 as a synaptobrevin/VAMP binding protein. (PubMed id 9188044)1, 2, 3, 9 Ravichandran V. and Roche P.A. (1997)
    2. Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing. (PubMed id 19536132)1, 2, 9 Laufman O....Lev S. (2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Distinct SNARE complexes mediating membrane fusion in Golgi transport based on combinatorial specificity. (PubMed id 11959998)1, 3 Parlati F....Rothman J.E. (2002)
    5. Localization, dynamics, and protein interactions reveal distinct roles for ER and Golgi SNAREs. (PubMed id 9647643)1, 9 Hay J.C....Scheller R.H. (1998)
    6. rsly1 binding to syntaxin 5 is required for endoplasmic reticulum-to-Golgi transport but does not promote SNARE motif accessibility. (PubMed id 14565970)1, 9 Williams A.L....Hay J.C. (2004)
    7. Syntaxin 5 is a common component of the NSF- and p97-mediated reassembly pathways of Golgi cisternae from mitotic Golgi fragments in vitro. (PubMed id 9506515)1, 9 Rabouille C....Warren G. (1998)
    8. Coordination of golgin tethering and SNARE assembly: GM130 binds syntaxin 5 in a p115-regulated manner. (PubMed id 18167358)1, 9 Diao A....Lowe M. (2008)
    9. Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins. (PubMed id 17389686)1, 9 Amessou M....Johannes L. (2007)
    10. Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network. (PubMed id 15215310)1, 9 Tai G.... Hong W. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6811 HGNC: 11440 AceView: STX5A Ensembl:ENSG00000162236 euGenes: HUgn6811
    ECgene: STX5 Kegg: 6811 H-InvDB: STX5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for STX5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for STX5 gene:
    Search GeneIP for patents involving STX5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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