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Aliases for STX19 Gene

Aliases for STX19 Gene

  • Syntaxin 19 2 3
  • Syntaxin-19 3

External Ids for STX19 Gene

Previous GeneCards Identifiers for STX19 Gene

  • GC03U900602
  • GC03M095217
  • GC03M093733
  • GC03M091095

Summaries for STX19 Gene

GeneCards Summary for STX19 Gene

STX19 (Syntaxin 19) is a Protein Coding gene. Among its related pathways are Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics and Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics. GO annotations related to this gene include SNAP receptor activity. An important paralog of this gene is STX4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STX19 Gene

Genomics for STX19 Gene

Regulatory Elements for STX19 Gene

Genomic Location for STX19 Gene

94,014,234 bp from pter
94,028,616 bp from pter
14,383 bases
Minus strand

Genomic View for STX19 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for STX19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STX19 Gene

Proteins for STX19 Gene

  • Protein details for STX19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:
    Secondary Accessions:

    Protein attributes for STX19 Gene

    294 amino acids
    Molecular mass:
    34324 Da
    Quaternary structure:
    No Data Available

neXtProt entry for STX19 Gene

Proteomics data for STX19 Gene at MOPED

Post-translational modifications for STX19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for STX19 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for STX19 Gene

Domains for STX19 Gene

Protein Domains for STX19 Gene

Suggested Antigen Peptide Sequences for STX19 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q8N4C7
  • Contains 1 t-SNARE coiled-coil homology domain.
  • Belongs to the syntaxin family.
genes like me logo Genes that share domains with STX19: view

No data available for Gene Families for STX19 Gene

Function for STX19 Gene

Gene Ontology (GO) - Molecular Function for STX19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000149 SNARE binding IBA --
GO:0005484 SNAP receptor activity IBA --
GO:0005515 protein binding IPI 23455924
genes like me logo Genes that share ontologies with STX19: view

Animal Model Products

miRNA for STX19 Gene

miRTarBase miRNAs that target STX19

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for STX19

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for STX19 Gene

Localization for STX19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for STX19 Gene

Membrane; Peripheral membrane protein.

Subcellular locations from

Jensen Localization Image for STX19 Gene COMPARTMENTS Subcellular localization image for STX19 gene
Compartment Confidence
cytosol 3
nucleus 2
extracellular 1

Gene Ontology (GO) - Cellular Components for STX19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IBA --
GO:0008021 synaptic vesicle IBA --
GO:0012505 endomembrane system IBA --
GO:0016020 membrane --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with STX19: view

Pathways for STX19 Gene

genes like me logo Genes that share pathways with STX19: view

Pathways by source for STX19 Gene

1 KEGG pathway for STX19 Gene

Gene Ontology (GO) - Biological Process for STX19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006886 intracellular protein transport IBA --
GO:0016192 vesicle-mediated transport --
GO:0031629 synaptic vesicle fusion to presynaptic membrane IBA --
GO:0048278 vesicle docking IBA --
genes like me logo Genes that share ontologies with STX19: view

Transcripts for STX19 Gene

mRNA/cDNA for STX19 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for STX19 Gene

Syntaxin 19:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for STX19

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for STX19 Gene

No ASD Table

Relevant External Links for STX19 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for STX19 Gene

mRNA expression in normal human tissues for STX19 Gene

mRNA differential expression in normal tissues according to GTEx for STX19 Gene

This gene is overexpressed in Colon - Transverse (9.5), Esophagus - Mucosa (6.5), Pancreas (4.9), Minor Salivary Gland (4.7), and Stomach (4.3).

SOURCE GeneReport for Unigene cluster for STX19 Gene Hs.679768

genes like me logo Genes that share expressions with STX19: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for STX19 Gene

Orthologs for STX19 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for STX19 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia STX19 35
  • 99.77 (n)
  • 99.32 (a)
STX19 36
  • 99 (a)
(Bos Taurus)
Mammalia STX19 35
  • 91.23 (n)
  • 88.77 (a)
STX19 36
  • 89 (a)
(Canis familiaris)
Mammalia STX19 35
  • 92.29 (n)
  • 90.82 (a)
STX19 36
  • 91 (a)
(Mus musculus)
Mammalia Stx19 35
  • 85.27 (n)
  • 86.3 (a)
Stx19 16
Stx19 36
  • 86 (a)
(Ornithorhynchus anatinus)
Mammalia STX19 36
  • 78 (a)
(Rattus norvegicus)
Mammalia Stx19 35
  • 84.93 (n)
  • 84.25 (a)
(Gallus gallus)
Aves STX19 35
  • 68.66 (n)
  • 62.68 (a)
STX19 36
  • 64 (a)
(Anolis carolinensis)
Reptilia STX19 36
  • 64 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia stx19 35
  • 64.78 (n)
  • 62.54 (a)
(Danio rerio)
Actinopterygii CT573248.1 36
  • 51 (a)
LOC570366 35
  • 55.59 (n)
  • 51.94 (a)
fruit fly
(Drosophila melanogaster)
Insecta Syx4 36
  • 14 (a)
(Caenorhabditis elegans)
Secernentea syx-2 36
  • 17 (a)
syx-3 36
  • 20 (a)
syx-4 36
  • 18 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SSO1 36
  • 16 (a)
SSO2 36
  • 16 (a)
Species with no ortholog for STX19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for STX19 Gene

Gene Tree for STX19 (if available)
Gene Tree for STX19 (if available)

Paralogs for STX19 Gene

Paralogs for STX19 Gene

Selected SIMAP similar genes for STX19 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with STX19: view

Variants for STX19 Gene

Relevant External Links for STX19 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for STX19 Gene

Disorders for STX19 Gene

No disorders were found for STX19 Gene.

No data available for UniProtKB/Swiss-Prot for STX19 Gene

Publications for STX19 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. A targeted siRNA screen to identify SNAREs required for constitutive secretion in mammalian cells. (PMID: 20545907) Gordon D.E. … Peden A.A. (Traffic 2010) 2 3
  3. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 3
  4. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R. … Iakoucheva L.M. (Nat. Commun. 2014) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for STX19 Gene

Sources for STX19 Gene

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