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Aliases for STX19 Gene

Aliases for STX19 Gene

  • Syntaxin 19 2 3 5

External Ids for STX19 Gene

Previous GeneCards Identifiers for STX19 Gene

  • GC03U900602
  • GC03M095217
  • GC03M093733
  • GC03M091095

Summaries for STX19 Gene

GeneCards Summary for STX19 Gene

STX19 (Syntaxin 19) is a Protein Coding gene. Among its related pathways are Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics. GO annotations related to this gene include SNARE binding and SNAP receptor activity. An important paralog of this gene is STX1B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STX19 Gene

Genomics for STX19 Gene

Regulatory Elements for STX19 Gene

Enhancers for STX19 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around STX19 on UCSC Golden Path with GeneCards custom track

Genomic Location for STX19 Gene

94,014,365 bp from pter
94,028,776 bp from pter
14,412 bases
Minus strand

Genomic View for STX19 Gene

Genes around STX19 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
STX19 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for STX19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STX19 Gene

Proteins for STX19 Gene

  • Protein details for STX19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:

    Protein attributes for STX19 Gene

    294 amino acids
    Molecular mass:
    34324 Da
    Quaternary structure:
    No Data Available

neXtProt entry for STX19 Gene

Proteomics data for STX19 Gene at MOPED

Post-translational modifications for STX19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for STX19 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for STX19 Gene

Domains & Families for STX19 Gene

Gene Families for STX19 Gene

Protein Domains for STX19 Gene

Suggested Antigen Peptide Sequences for STX19 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 t-SNARE coiled-coil homology domain.
  • Belongs to the syntaxin family.
  • Contains 1 t-SNARE coiled-coil homology domain.
  • Belongs to the syntaxin family.
genes like me logo Genes that share domains with STX19: view

Function for STX19 Gene

Gene Ontology (GO) - Molecular Function for STX19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000149 SNARE binding IBA --
GO:0005484 SNAP receptor activity IEA,IBA --
genes like me logo Genes that share ontologies with STX19: view
genes like me logo Genes that share phenotypes with STX19: view

Animal Models for STX19 Gene

MGI Knock Outs for STX19:

Animal Model Products

miRNA for STX19 Gene

miRTarBase miRNAs that target STX19

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for STX19 Gene

Localization for STX19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for STX19 Gene

Membrane; Peripheral membrane protein.

Subcellular locations from

Jensen Localization Image for STX19 Gene COMPARTMENTS Subcellular localization image for STX19 gene
Compartment Confidence
cytosol 3
plasma membrane 3
nucleus 2
extracellular 1

Gene Ontology (GO) - Cellular Components for STX19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008021 synaptic vesicle IBA --
GO:0016021 integral component of membrane IBA --
GO:0031201 SNARE complex IBA --
genes like me logo Genes that share ontologies with STX19: view

Pathways & Interactions for STX19 Gene

genes like me logo Genes that share pathways with STX19: view

Pathways by source for STX19 Gene

1 KEGG pathway for STX19 Gene

Gene Ontology (GO) - Biological Process for STX19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016192 vesicle-mediated transport IEA --
genes like me logo Genes that share ontologies with STX19: view

No data available for SIGNOR curated interactions for STX19 Gene

Drugs & Compounds for STX19 Gene

No Compound Related Data Available

Transcripts for STX19 Gene

mRNA/cDNA for STX19 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for STX19 Gene

Syntaxin 19:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for STX19 Gene

No ASD Table

Relevant External Links for STX19 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for STX19 Gene

mRNA expression in normal human tissues for STX19 Gene

mRNA differential expression in normal tissues according to GTEx for STX19 Gene

This gene is overexpressed in Colon - Transverse (x9.5), Esophagus - Mucosa (x6.5), Pancreas (x4.9), Minor Salivary Gland (x4.7), and Stomach (x4.3).

SOURCE GeneReport for Unigene cluster for STX19 Gene Hs.679768

genes like me logo Genes that share expression patterns with STX19: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for STX19 Gene

Orthologs for STX19 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for STX19 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia STX19 35
  • 91.23 (n)
  • 88.77 (a)
STX19 36
  • 89 (a)
(Canis familiaris)
Mammalia STX19 35
  • 92.29 (n)
  • 90.82 (a)
STX19 36
  • 91 (a)
(Mus musculus)
Mammalia Stx19 35
  • 85.27 (n)
  • 86.3 (a)
Stx19 16
Stx19 36
  • 86 (a)
(Pan troglodytes)
Mammalia STX19 35
  • 99.77 (n)
  • 99.32 (a)
STX19 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Stx19 35
  • 84.93 (n)
  • 84.25 (a)
(Ornithorhynchus anatinus)
Mammalia STX19 36
  • 78 (a)
(Gallus gallus)
Aves STX19 35
  • 68.66 (n)
  • 62.68 (a)
STX19 36
  • 64 (a)
(Anolis carolinensis)
Reptilia STX19 36
  • 64 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia stx19 35
  • 64.78 (n)
  • 62.54 (a)
(Danio rerio)
Actinopterygii LOC570366 35
  • 55.59 (n)
  • 51.94 (a)
CT573248.1 36
  • 51 (a)
fruit fly
(Drosophila melanogaster)
Insecta Syx4 36
  • 14 (a)
(Caenorhabditis elegans)
Secernentea syx-2 36
  • 17 (a)
syx-3 36
  • 20 (a)
syx-4 36
  • 18 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SSO1 36
  • 16 (a)
SSO2 36
  • 16 (a)
Species with no ortholog for STX19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for STX19 Gene

Gene Tree for STX19 (if available)
Gene Tree for STX19 (if available)

Paralogs for STX19 Gene

Paralogs for STX19 Gene

(9) SIMAP similar genes for STX19 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with STX19: view

Variants for STX19 Gene

Variation tolerance for STX19 Gene

Residual Variation Intolerance Score: 51.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.04; 21.29% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for STX19 Gene

Disorders for STX19 Gene

Relevant External Links for STX19

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for STX19 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for STX19 Gene

Publications for STX19 Gene

  1. A targeted siRNA screen to identify SNAREs required for constitutive secretion in mammalian cells. (PMID: 20545907) Gordon D.E. … Peden A.A. (Traffic 2010) 2 3 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R. … Iakoucheva L.M. (Nat. Commun. 2014) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 3

Products for STX19 Gene

Sources for STX19 Gene