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Aliases for STX16-NPEPL1 Gene

Subcategory (RNA class) for STX16-NPEPL1 Gene


Quality Score for this RNA gene is


Aliases for STX16-NPEPL1 Gene

  • STX16-NPEPL1 Readthrough (NMD Candidate) 2 3

External Ids for STX16-NPEPL1 Gene

Previous GeneCards Identifiers for STX16-NPEPL1 Gene

  • GC20U900674
  • GC20P057228
  • GC20P057229

Summaries for STX16-NPEPL1 Gene

Entrez Gene Summary for STX16-NPEPL1 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring syntaxin 16 (STX16) and aminopeptidase-like 1 (NPEPL1) genes on chromosome 20. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Mar 2011]

GeneCards Summary for STX16-NPEPL1 Gene

STX16-NPEPL1 (STX16-NPEPL1 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. An important paralog of this gene is STX16.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STX16-NPEPL1 Gene

Genomics for STX16-NPEPL1 Gene

Genomic Location for STX16-NPEPL1 Gene

58,651,253 bp from pter
58,715,844 bp from pter
64,592 bases
Plus strand

Genomic View for STX16-NPEPL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for STX16-NPEPL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STX16-NPEPL1 Gene

No data available for Regulatory Elements for STX16-NPEPL1 Gene

Proteins for STX16-NPEPL1 Gene

  • Protein details for STX16-NPEPL1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein STX16-NPEPL1
    Protein Accession:
    Secondary Accessions:

    Protein attributes for STX16-NPEPL1 Gene

    382 amino acids
    Molecular mass:
    43229 Da
    Quaternary structure:
    No Data Available

neXtProt entry for STX16-NPEPL1 Gene

Proteomics data for STX16-NPEPL1 Gene at MOPED

Post-translational modifications for STX16-NPEPL1 Gene

No Post-translational modifications

Other Protein References for STX16-NPEPL1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for STX16-NPEPL1 Gene

Domains for STX16-NPEPL1 Gene

Protein Domains for STX16-NPEPL1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with STX16-NPEPL1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for STX16-NPEPL1 Gene

Function for STX16-NPEPL1 Gene

Gene Ontology (GO) - Molecular Function for STX16-NPEPL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005484 SNAP receptor activity --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with STX16-NPEPL1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for STX16-NPEPL1 Gene

Localization for STX16-NPEPL1 Gene

Gene Ontology (GO) - Cellular Components for STX16-NPEPL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus --
GO:0016020 membrane --
GO:0031201 SNARE complex --
GO:0043231 intracellular membrane-bounded organelle --
genes like me logo Genes that share ontologies with STX16-NPEPL1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for STX16-NPEPL1 Gene

Pathways for STX16-NPEPL1 Gene

SuperPathways for STX16-NPEPL1 Gene

No Data Available

Interacting Proteins for STX16-NPEPL1 Gene

Gene Ontology (GO) - Biological Process for STX16-NPEPL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006886 intracellular protein transport --
GO:0006891 intra-Golgi vesicle-mediated transport --
GO:0016192 vesicle-mediated transport --
genes like me logo Genes that share ontologies with STX16-NPEPL1: view

No data available for Pathways by source for STX16-NPEPL1 Gene

Transcripts for STX16-NPEPL1 Gene

mRNA/cDNA for STX16-NPEPL1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for STX16-NPEPL1 Gene

No ASD Table

Relevant External Links for STX16-NPEPL1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for STX16-NPEPL1 Gene

mRNA expression in normal human tissues for STX16-NPEPL1 Gene

mRNA differential expression in normal tissues according to GTEx for STX16-NPEPL1 Gene

This gene is overexpressed in Brain - Cerebellum (5.7) and Brain - Cerebellar Hemisphere (4.2).
genes like me logo Genes that share expressions with STX16-NPEPL1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for STX16-NPEPL1 Gene

Orthologs for STX16-NPEPL1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for STX16-NPEPL1 Gene

Organism Taxonomy Gene Similarity Type Details
(Monodelphis domestica)
Mammalia -- 36
  • 84 (a)
(Mus musculus)
Mammalia Stx16 36
  • 87 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 83 (a)
(Pan troglodytes)
Mammalia STX16-NPEPL1 36
  • 98 (a)
(Gallus gallus)
Aves STX16 36
  • 79 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 77 (a)
(Danio rerio)
Actinopterygii stx16 36
  • 72 (a)
fruit fly
(Drosophila melanogaster)
Insecta Syx16 36
  • 32 (a)
(Caenorhabditis elegans)
Secernentea syx-16 36
  • 27 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes TLG2 36
  • 18 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 45 (a)
Species with no ortholog for STX16-NPEPL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for STX16-NPEPL1 Gene

Gene Tree for STX16-NPEPL1 (if available)
Gene Tree for STX16-NPEPL1 (if available)

Paralogs for STX16-NPEPL1 Gene

Paralogs for STX16-NPEPL1 Gene

(1) SIMAP similar genes for STX16-NPEPL1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with STX16-NPEPL1: view

Variants for STX16-NPEPL1 Gene

Sequence variations from dbSNP and Humsavar for STX16-NPEPL1 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs1015871 -- 58,682,263(+) TTTCA(A/G)TTTGT intron-variant
rs2006908 -- 58,681,476(-) GGCCT(C/T)CCAAA intron-variant
rs2031538 -- 58,683,107(+) TTTTT(A/T)AATCC intron-variant
rs2182249 -- 58,682,769(+) GAGAC(C/T)GGCTG intron-variant
rs4812024 -- 58,678,240(+) AGGAA(A/G)GTGAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for STX16-NPEPL1 Gene

Variant ID Type Subtype PubMed ID
nsv828761 CNV Loss 20364138
esv1002410 CNV Deletion 20482838
nsv912963 CNV Gain 21882294
esv2558295 CNV Insertion 19546169
esv1198718 CNV Insertion 17803354
nsv513552 CNV Insertion 21212237
nsv828762 CNV Loss 20364138
esv2665738 CNV Deletion 23128226

Relevant External Links for STX16-NPEPL1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for STX16-NPEPL1 Gene

Disorders for STX16-NPEPL1 Gene

No disorders were found for STX16-NPEPL1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for STX16-NPEPL1 Gene

Publications for STX16-NPEPL1 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3

Products for STX16-NPEPL1 Gene

Sources for STX16-NPEPL1 Gene

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