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Aliases for STX16-NPEPL1 Gene

Subcategory (RNA class) for STX16-NPEPL1 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for STX16-NPEPL1 Gene

  • STX16-NPEPL1 Readthrough (NMD Candidate) 2 3 5

External Ids for STX16-NPEPL1 Gene

Previous GeneCards Identifiers for STX16-NPEPL1 Gene

  • GC20U900674
  • GC20P057228
  • GC20P057229

Summaries for STX16-NPEPL1 Gene

Entrez Gene Summary for STX16-NPEPL1 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring syntaxin 16 (STX16) and aminopeptidase-like 1 (NPEPL1) genes on chromosome 20. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Mar 2011]

GeneCards Summary for STX16-NPEPL1 Gene

STX16-NPEPL1 (STX16-NPEPL1 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. GO annotations related to this gene include SNAP receptor activity. An important paralog of this gene is STX16.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STX16-NPEPL1 Gene

Genomics for STX16-NPEPL1 Gene

Regulatory Elements for STX16-NPEPL1 Gene

Enhancers for STX16-NPEPL1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around STX16-NPEPL1 on UCSC Golden Path with GeneCards custom track

Promoters for STX16-NPEPL1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around STX16-NPEPL1 on UCSC Golden Path with GeneCards custom track

Genomic Location for STX16-NPEPL1 Gene

Chromosome:
20
Start:
58,651,253 bp from pter
End:
58,715,844 bp from pter
Size:
64,592 bases
Orientation:
Plus strand

Genomic View for STX16-NPEPL1 Gene

Genes around STX16-NPEPL1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
STX16-NPEPL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for STX16-NPEPL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STX16-NPEPL1 Gene

Proteins for STX16-NPEPL1 Gene

  • Protein details for STX16-NPEPL1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BU86
    Recommended name:
    Protein STX16-NPEPL1
    Protein Accession:
    H3BU86

    Protein attributes for STX16-NPEPL1 Gene

    Size:
    382 amino acids
    Molecular mass:
    43229 Da
    Quaternary structure:
    No Data Available

neXtProt entry for STX16-NPEPL1 Gene

Proteomics data for STX16-NPEPL1 Gene at MOPED

Post-translational modifications for STX16-NPEPL1 Gene

No Post-translational modifications

Other Protein References for STX16-NPEPL1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for STX16-NPEPL1 Gene

Domains & Families for STX16-NPEPL1 Gene

Protein Domains for STX16-NPEPL1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with STX16-NPEPL1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for STX16-NPEPL1 Gene

Function for STX16-NPEPL1 Gene

Gene Ontology (GO) - Molecular Function for STX16-NPEPL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005484 SNAP receptor activity IEA --
genes like me logo Genes that share ontologies with STX16-NPEPL1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for STX16-NPEPL1 Gene

Localization for STX16-NPEPL1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for STX16-NPEPL1 Gene COMPARTMENTS Subcellular localization image for STX16-NPEPL1 gene
Compartment Confidence
endosome 2
golgi apparatus 2
plasma membrane 1

Gene Ontology (GO) - Cellular Components for STX16-NPEPL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with STX16-NPEPL1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for STX16-NPEPL1 Gene

Pathways & Interactions for STX16-NPEPL1 Gene

SuperPathways for STX16-NPEPL1 Gene

No Data Available

Interacting Proteins for STX16-NPEPL1 Gene

Gene Ontology (GO) - Biological Process for STX16-NPEPL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006906 vesicle fusion IBA --
GO:0016192 vesicle-mediated transport IEA --
genes like me logo Genes that share ontologies with STX16-NPEPL1: view

No data available for Pathways by source and SIGNOR curated interactions for STX16-NPEPL1 Gene

Drugs & Compounds for STX16-NPEPL1 Gene

No Compound Related Data Available

Transcripts for STX16-NPEPL1 Gene

mRNA/cDNA for STX16-NPEPL1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for STX16-NPEPL1 Gene

No ASD Table

Relevant External Links for STX16-NPEPL1 Gene

GeneLoc Exon Structure for
STX16-NPEPL1
ECgene alternative splicing isoforms for
STX16-NPEPL1

Expression for STX16-NPEPL1 Gene

mRNA expression in normal human tissues for STX16-NPEPL1 Gene

mRNA differential expression in normal tissues according to GTEx for STX16-NPEPL1 Gene

This gene is overexpressed in Brain - Cerebellum (x5.7) and Brain - Cerebellar Hemisphere (x4.2).
genes like me logo Genes that share expression patterns with STX16-NPEPL1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for STX16-NPEPL1 Gene

Orthologs for STX16-NPEPL1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for STX16-NPEPL1 Gene

Organism Taxonomy Gene Similarity Type Details
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 84 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Stx16 36
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 83 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia STX16-NPEPL1 36
  • 98 (a)
OneToOne
chicken
(Gallus gallus)
Aves STX16 36
  • 79 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 77 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii stx16 36
  • 72 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Syx16 36
  • 32 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea syx-16 36
  • 27 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes TLG2 36
  • 18 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 45 (a)
OneToMany
Species with no ortholog for STX16-NPEPL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for STX16-NPEPL1 Gene

ENSEMBL:
Gene Tree for STX16-NPEPL1 (if available)
TreeFam:
Gene Tree for STX16-NPEPL1 (if available)

Paralogs for STX16-NPEPL1 Gene

Paralogs for STX16-NPEPL1 Gene

(1) SIMAP similar genes for STX16-NPEPL1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with STX16-NPEPL1: view

Variants for STX16-NPEPL1 Gene

Sequence variations from dbSNP and Humsavar for STX16-NPEPL1 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1015871 -- 58,682,263(+) TTTCA(A/G)TTTGT intron-variant
rs2006908 -- 58,681,476(-) GGCCT(C/T)CCAAA intron-variant
rs2031538 -- 58,683,107(+) TTTTT(A/T)AATCC intron-variant
rs2182249 -- 58,682,769(+) GAGAC(C/T)GGCTG intron-variant
rs6015337 -- 58,687,009(+) ACATG(C/T)GCACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for STX16-NPEPL1 Gene

Variant ID Type Subtype PubMed ID
nsv828761 CNV Loss 20364138
esv1002410 CNV Deletion 20482838
nsv912963 CNV Gain 21882294
esv2558295 CNV Insertion 19546169
esv1198718 CNV Insertion 17803354
nsv513552 CNV Insertion 21212237
nsv828762 CNV Loss 20364138
esv2665738 CNV Deletion 23128226

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for STX16-NPEPL1 Gene

Disorders for STX16-NPEPL1 Gene

Relevant External Links for STX16-NPEPL1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
STX16-NPEPL1

No disorders were found for STX16-NPEPL1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for STX16-NPEPL1 Gene

Publications for STX16-NPEPL1 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 67

Products for STX16-NPEPL1 Gene

Sources for STX16-NPEPL1 Gene

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