External Ids for STX16 Gene
Previous GeneCards Identifiers for STX16 Gene
This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants have been found for this gene. Read-through transcription also exists between this gene and the neighboring downstream aminopeptidase-like 1 (NPEPL1) gene. [provided by RefSeq, Mar 2011]
GeneCards Summary for STX16 Gene
STX16 (Syntaxin 16) is a Protein Coding gene. Diseases associated with STX16 include pseudohypoparathyroidism, type ib and pseudohypoparathyroidism. Among its related pathways are Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics and Golgi-to-ER retrograde transport. GO annotations related to this gene include syntaxin binding and SNAP receptor activity. An important paralog of this gene is STX16-NPEPL1.
UniProtKB/Swiss-Prot for STX16 Gene
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.