External Ids for STX16 Gene
This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants have been found for this gene. Read-through transcription also exists between this gene and the neighboring downstream aminopeptidase-like 1 (NPEPL1) gene. [provided by RefSeq, Mar 2011]
GeneCards Summary for STX16 Gene
STX16 (Syntaxin 16) is a Protein Coding gene. Diseases associated with STX16 include pseudohypoparathyroidism, type ib and pseudohypoparathyroidism. Among its related pathways are Disease and Transmission across Chemical Synapses. GO annotations related to this gene include SNAP receptor activity. An important paralog of this gene is STX16-NPEPL1.
UniProtKB/Swiss-Prot for STX16 Gene
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.