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STRBP Gene

protein-coding GIFtS: 51
GCID: GC09M125871

Spermatid Perinuclear RNA Binding Protein

(Previous names: spermatid perinuclear RNA-binding protein, interleukin enhancer...)
(Previous symbol: ILF3L)

See related diseases
at

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
Spermatid Perinuclear RNA Binding Protein¹ ²		p74² ⁵
SPNR² ³ ⁵		Interleukin Enhancer Binding Factor 3-Like¹
ILF3L¹ ²		HEL162²
Spermatid Perinuclear RNA-Binding Protein¹ ²		Epididymis Luminal Protein 162²

External Ids:	HGNC: 16462¹	Entrez Gene: 55342²	Ensembl: ENSG00000165209⁷	OMIM: 611138⁵	UniProtKB: Q96SI9³

Export aliases for STRBP gene to outside databases

Previous GC identifers: GC09M116991 GC09M117533 GC09M119340 GC09M121263 GC09M122966 GC09M124926 GC09M095498

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for STRBP Gene:

STRBP (spermatid perinuclear RNA binding protein) is a protein-coding gene. Diseases associated with STRBP include louping ill, and murray valley encephalitis. GO annotations related to this gene include double-stranded RNA binding and single-stranded RNA binding. An important paralog of this gene is ZFR2.

UniProtKB/Swiss-Prot: STRBP_HUMAN, Q96SI9

Function: Involved in spermatogenesis and sperm function. Plays a role in regulation of cell growth. Binds to

double-stranded DNA and RNA. Binds most efficiently to poly(I:C) RNA than to poly(dI:dC) DNA. Binds also to

single-stranded poly(G) RNA. Binds non-specifically to the mRNA PRM1 3'-UTR and adenovirus VA RNA (By similarity)

Gene Wiki entry for STRBP Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:

Regulatory transcription factor binding sites in the STRBP gene promoter:
ATF-2 COMP1 RORalpha2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: STRBP promoter sequence

Search Chromatin IP Primers for STRBP

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat STRBP

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q33.3 Ensembl cytogenetic band: 9q33.3 HGNC cytogenetic band: 9q33.1-q33.3

STRBP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STRBP gene location

GeneLoc information about chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09M125871: view genomic region (about GC identifiers)

Start:	125,871,779 bp from pter	End:	126,030,855 bp from pter
Size:	159,077 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: STRBP_HUMAN, Q96SI9 (See protein sequence)

Recommended Name: Spermatid perinuclear RNA-binding protein

Size: 672 amino acids; 73653 Da

Subunit: Interacts with EIF2AK2 (By similarity). Associates with microtubules; it is unsure whether such

interaction is direct or indirect (By similarity)

Sequence caution: Sequence=AAI08732.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential

poly-A sequence; Sequence=BAA92120.1; Type=Erroneous initiation; Sequence=BAB14873.1; Type=Erroneous initiation;

1 PDB 3D structure from and Proteopedia for STRBP:

2DMY (3D)

Secondary accessions: Q32NB9 Q9BUE1 Q9BXG4 Q9H0B4 Q9H7V1 Q9NUK4

Alternative splicing: 2 isoforms: Q96SI9-1 Q96SI9-2

Explore the universe of human proteins at neXtProt for STRBP: NX_Q96SI9

Explore proteomics data for STRBP at MOPED

Post-translational modifications:

Ubiquitination² at Lys339, Lys526

Modification sites at PhosphoSitePlus

See STRBP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts):

NP_001164608.1 NP_060857.2

ENSEMBL proteins:

ENSP00000432626 ENSP00000433106 ENSP00000431190 ENSP00000321347 ENSP00000354271

ENSP00000384292 ENSP00000431531 ENSP00000415968

STRBP Human Recombinant Protein Products:

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STRBP Assay Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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2 InterPro protein domains:

IPR014720 dsRNA-bd_dom

IPR006561 DZF

Graphical View of Domain Structure for InterPro Entry Q96SI9

ProtoNet protein and cluster: Q96SI9

1 Blocks protein domain: IPB001159 Double-stranded RNA binding (DsRBD) domain

UniProtKB/Swiss-Prot: STRBP_HUMAN, Q96SI9

Similarity: Contains 2 DRBM (double-stranded RNA-binding) domains

Similarity: Contains 1 DZF domain

STRBP for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: STRBP_HUMAN, Q96SI9

Function: Involved in spermatogenesis and sperm function. Plays a role in regulation of cell growth. Binds to

double-stranded DNA and RNA. Binds most efficiently to poly(I:C) RNA than to poly(dI:dC) DNA. Binds also to

single-stranded poly(G) RNA. Binds non-specifically to the mRNA PRM1 3'-UTR and adenovirus VA RNA (By similarity)

Gene Ontology (GO): 4 molecular function terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0003725	double-stranded RNA binding	IEA	--
GO:0003727	single-stranded RNA binding	IEA	--
GO:0044822	poly(A) RNA binding	IDA	--

STRBP for ontologies About GeneDecksing

Phenotypes:
6 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Strbp):

behavior/neurological	endocrine/exocrine gland	growth/size/body	mortality/aging	nervous system
reproductive system

STRBP for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for STRBP

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genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for STRBP

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for STRBP

miRNA Products:		miRTarBase miRNAs that target STRBP: hsa-mir-92b-3p (MIRT040658), hsa-mir-130b-3p (MIRT020149), hsa-mir-155-5p (MIRT020761), hsa-mir-21-5p (MIRT030912), hsa-mir-33a-5p (MIRT028221), hsa-mir-375 (MIRT019861)

		Block miRNA regulation of human, mouse, rat STRBP using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate STRBP (see all 89):
		hsa-miR-124* hsa-miR-607 hsa-miR-300 hsa-miR-15a hsa-miR-146a hsa-miR-219-5p hsa-miR-409-5p hsa-miR-376a*

		SwitchGear 3'UTR luciferase reporter plasmid: STRBP 3' UTR sequence

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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STRBP

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

STRBP_HUMAN, Q96SI9: Cytoplasm (By similarity). Note=Microtubule-associated that localizes to the manchette in

developing spermatids (By similarity)

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
nucleus	4
cytoskeleton	2
cytosol	2

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Gene Ontology (GO): 3 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005737	cytoplasm	IEA	--
GO:0015630	microtubule cytoskeleton	IEA	--

STRBP for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for STRBP
Interactions:

Search GeneGlobe Interaction Network for STRBP

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

Selected Interacting proteins for STRBP (Q96SI9^{2, 3} ENSP00000321347⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 28)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RBPMS	Q93062²^,³, ENSP00000340176⁴	MINT-66074 I2D: score=5 STRING: ENSP00000340176
THAP1	Q9NVV9²^,³, ENSP00000254250⁴	MINT-68310 I2D: score=5 STRING: ENSP00000254250
EIF2AK2	P19525³, ENSP00000233057⁴	I2D: score=1 STRING: ENSP00000233057
ATG101	Q9BSB4³	I2D: score=1
CLN3	Q13286³	I2D: score=1

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Gene Ontology (GO): 4 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006928	cellular component movement	IEA	--
GO:0007275	multicellular organismal development	IEA	--
GO:0007286	spermatid development	IEA	--
GO:0007638	mechanosensory behavior	IEA	--

STRBP for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for STRBP

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for STRBP gene (2 alternative transcripts):

NM_001171137.1 NM_018387.4

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000530364 ENST00000478973 ENST00000471564 ENST00000496533 ENST00000348403

ENST00000360998 ENST00000407982 ENST00000492885 ENST00000479114 ENST00000447404(uc004bnt.3 uc004bnu.3 uc004bns.3 uc004bnv.3)

miRNA Products:		Block miRNA regulation of human, mouse, rat STRBP using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate STRBP (see all 89):
		hsa-miR-124* hsa-miR-607 hsa-miR-300 hsa-miR-15a hsa-miR-146a hsa-miR-219-5p hsa-miR-409-5p hsa-miR-376a*

		SwitchGear 3'UTR luciferase reporter plasmid: STRBP 3' UTR sequence

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Primer Products:		OriGene qPCR primer pairs and template standards for STRBP OriGene qSTAR qPCR primer pairs in human, mouse for STRBP
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat STRBP
		QuantiTect SYBR Green Assays in human, mouse, rat STRBP
		QuantiFast Probe-based Assays in human, mouse, rat STRBP

Selected AceView cDNA sequences (see all 263):

AA836810 BG315203 AI025833 BG113333 BM704833 CD299947 AW183150 BM728734

BM979986 BQ002726 AK123844 BQ440741 BU742655 BM904147 AW055268 AI090248

BU730467 BC034918 AK002169 BM666384 CR596677 CB135362 AK024285 BG107710

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for STRBP About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6a	·	6b	^	7	^	8	^	9	^	10	^	11	^	12a	·	12b	^	13a	·	13b	^	14	^	15	^	16	^	17	^	18	^	19
SP1:			-
SP2:
SP3:																																	-
SP4:																																	-

ECgene alternative splicing isoforms for STRBP

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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STRBP expression in normal human tissues (normalized intensities) STRBP embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: ACAAGCGCTT

About this image

STRBP expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 5) fully expand


Brain (Nervous System) fully expand to see all 4 entries
Cerebral Cortex

Inner Cell Mass (Early Embryonic Tissues) fully expand to see all 2 entries
Human embryonic stem cells (family)

Neurons
GABAergic Amacrine Cells Inner Nuclear Layer

Gonad (Reproductive System)
Primordial Germ Cells Primitive Gonad

Eye (Sensory Organs)
GABAergic Amacrine Cells Inner Nuclear Layer

STRBP Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

STRBP Protein Expression

Custom PCR Arrays for STRBP

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STRBP

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for STRBP gene from Selected species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Strbp^{1 , 5}	spermatid perinuclear RNA binding protein^{1, 5}	94.05(n)¹ 98.96(a)¹		2 (24.19 cM)⁵ 20744¹ NM_009261.3¹ NP_033287.2¹ 37483228⁵
chicken (Gallus gallus)	Aves	STRBP¹	spermatid perinuclear RNA binding protein	85.44(n) 92.25(a)		417105 NM_001030680.1 NP_001025851.1
lizard (Anolis carolinensis)	Reptilia	STRBP⁶	spermatid perinuclear RNA binding protein	86(a)	1 ↔ 1	GL343751.1(150847-199077)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.15971²	Transcribed sequence with weak similarity to protein more	77.61(n)		AL855766.2
zebrafish (Danio rerio)	Actinopterygii	strbp¹	spermatid perinuclear RNA binding protein	70.73(n) 79.1(a)		557957 XM_701955.5 XP_707047.3
worm (Caenorhabditis elegans)	Secernentea	Y95B8A.8⁶	Protein Y95B8A.8 (Y95B8A.8) mRNA, complete cds	14(a)	1 → many	I(853451-871947) WBGene00022388

ENSEMBL Gene Tree for STRBP (if available)
TreeFam Gene Tree for STRBP (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for STRBP gene

ZFR2² ILF2² ILF3² ZFR²

4 SIMAP similar genes for STRBP using alignment to 5 protein entries: STRBP_HUMAN (see all proteins):

DKFZp434P151 ILF3 ZFR ZFR2

STRBP for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 9 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
VAR_035662⁴		A breast cancer sample⁴	--	see VAR_035662	2	G R	mis⁴		0	--	--	--	--
rs181430556^1,2		--	125883587(+)	`AAATAC/TAGCCT`	3	--	ds500¹		0	--	--	--	--
rs186525691^1,2		--	125883721(+)	`TGGGAA/GATAAA`	3	--	ds500¹		0	--	--	--	--
rs146186273^1,2		--	125883798(+)	`CGATAC/TTCACC`	3	--	ds500¹		0	--	--	--	--
rs200399477^1,2	C	--	125883895(+)	`TTTTTG/TTTTTT`	3	--	ds500¹		0	--	--	--	--
rs55974272^1,2	C	--	125883896(+)	`TTTTG-/TTTTTT`	3	--	ds500¹		2		NA CSA	4
rs202183275^1,2	C	--	125883903(-)	`AAAAAA/GAAAAA`	3	--	ut3¹ nc-transcript-variant		0	--	--	--	--
rs10985890^1,2	C,F	--	125884052(+)	`TTACAC/TATACA`	3	--	ut3¹ nc-transcript-variant		5		NA WA	244
rs190991849^1,2		--	125884075(+)	`ACTATG/TACCAA`	3	--	ut3¹ nc-transcript-variant		0	--	--	--	--
rs60112664^1,2	C	--	125884228(+)	`TTTCT-/ACACACA`	3	--	ut3¹ nc-transcript-variant		0	--	--	--	--

HapMap Linkage Disequilibrium report for STRBP (125871779 - 126030855 bp)

Structural Variations
Database of Genomic Variants (DGV) 7 variations for STRBP: About this table

Variant ID	Type	Subtype	PubMed ID
esv2658555	CNV	Deletion	23128226
nsv6706	CNV	Insertion	18451855
esv25223	CNV	Loss	19812545
nsv893826	CNV	Loss	21882294
esv1008345	CNV	Loss	20482838
nsv831717	CNV	Gain	17160897
nsv893825	CNV	Gain	21882294

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing STRBP

DNA2.0 Custom Variant and Variant Library Synthesis for STRBP

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 611138 OMIM disorders: --

11 diseases for STRBP: About MalaCards

louping ill murray valley encephalitis opisthorchiasis cryptorchidism

encephalitis down syndrome breast and colorectal cancer colorectal cancer

multiple myeloma myeloma cerebritis

STRBP for disorders About GeneDecksing

Genetic Association Database (GAD): STRBP

Export disorders for STRBP gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for STRBP gene, integrated from 10 sources (see all 30):
(articles sorted by number of sources associating them with STRBP)

Utopia: connect your pdf to the dynamic
world of online information

DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)^{1, 2} Humphray S.J.... Dunham I. (Nature 2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)^{1, 2} Wiemann S.... Poustka A. (Genome Res. 2001)
Mice deficient for spermatid perinuclear RNA-binding protein show neurologic, spermatogenic, and sperm morphological abnormalities. (PubMed id 11336498)^{1, 9} Pires-daSilva A....Gruss P. (Dev. Biol. 2001)
Screening of LRRK2 interactants by yeast 2-hybrid analysis. (PubMed id 19001729)^{1, 9} Zheng X.Y....Zhang Z.H. (Zhong Nan Da Xue Xue Bao Yi Xue Ban 2008)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (Cell 2012)
Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)¹ Lopitz-Otsoa F....Rodriguez M.S. (J Proteomics 2012)
Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)¹ Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
Expression of STRBP mRNA in patients with cryptorchidism and Down's syndrome. (PubMed id 22391137)¹ Salemi M....Calogero A.E. (J. Endocrinol. Invest. 2012)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 55342	HGNC: 16462	AceView: STRBPandC9orf45	Ensembl:ENSG00000165209	euGenes: HUgn55342
ECgene: STRBP	H-InvDB: STRBP

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for STRBP	Pharmacogenomics, SNPs, Pathways

Intellectual Property for STRBP gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for STRBP gene:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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STRBP Gene

Spermatid Perinuclear RNA Binding Protein

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STRBP Gene

Spermatid Perinuclear RNA Binding Protein

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