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STRBP Gene

protein-coding   GIFtS: 51
GCID: GC09M125871

Spermatid Perinuclear RNA Binding Protein

(Previous names: spermatid perinuclear RNA-binding protein, interleukin enhancer...)
(Previous symbol: ILF3L)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Spermatid Perinuclear RNA Binding Protein1 2     p742 5
SPNR2 3 5     Interleukin Enhancer Binding Factor 3-Like1
ILF3L1 2     HEL1622
Spermatid Perinuclear RNA-Binding Protein1 2     Epididymis Luminal Protein 1622

External Ids:    HGNC: 164621   Entrez Gene: 553422   Ensembl: ENSG000001652097   OMIM: 6111385   UniProtKB: Q96SI93   

Export aliases for STRBP gene to outside databases

Previous GC identifers: GC09M116991 GC09M117533 GC09M119340 GC09M121263 GC09M122966 GC09M124926 GC09M095498


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for STRBP Gene:
STRBP (spermatid perinuclear RNA binding protein) is a protein-coding gene. Diseases associated with STRBP include louping ill, and murray valley encephalitis. GO annotations related to this gene include double-stranded RNA binding and single-stranded RNA binding. An important paralog of this gene is ZFR2.

UniProtKB/Swiss-Prot: STRBP_HUMAN, Q96SI9
Function: Involved in spermatogenesis and sperm function. Plays a role in regulation of cell growth. Binds to
double-stranded DNA and RNA. Binds most efficiently to poly(I:C) RNA than to poly(dI:dC) DNA. Binds also to
single-stranded poly(G) RNA. Binds non-specifically to the mRNA PRM1 3'-UTR and adenovirus VA RNA (By similarity)

Gene Wiki entry for STRBP Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the STRBP gene promoter:
         ATF-2   COMP1   RORalpha2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTRBP promoter sequence
   Search Chromatin IP Primers for STRBP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat STRBP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q33.3   Ensembl cytogenetic band:  9q33.3   HGNC cytogenetic band: 9q33.1-q33.3

STRBP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STRBP gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M125871:  view genomic region     (about GC identifiers)

Start:
125,871,779 bp from pter      End:
126,030,855 bp from pter
Size:
159,077 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: STRBP_HUMAN, Q96SI9 (See protein sequence)
Recommended Name: Spermatid perinuclear RNA-binding protein  
Size: 672 amino acids; 73653 Da
Subunit: Interacts with EIF2AK2 (By similarity). Associates with microtubules; it is unsure whether such
interaction is direct or indirect (By similarity)
Sequence caution: Sequence=AAI08732.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence; Sequence=BAA92120.1; Type=Erroneous initiation; Sequence=BAB14873.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for STRBP:
2DMY (3D)    
Secondary accessions: Q32NB9 Q9BUE1 Q9BXG4 Q9H0B4 Q9H7V1 Q9NUK4
Alternative splicing: 2 isoforms:  Q96SI9-1   Q96SI9-2   

Explore the universe of human proteins at neXtProt for STRBP: NX_Q96SI9

Explore proteomics data for STRBP at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys339, Lys526
  • Modification sites at PhosphoSitePlus

  • See STRBP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001164608.1  NP_060857.2  

    ENSEMBL proteins: 
     ENSP00000432626   ENSP00000433106   ENSP00000431190   ENSP00000321347   ENSP00000354271  
     ENSP00000384292   ENSP00000431531   ENSP00000415968  

    STRBP Human Recombinant Protein Products:

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    Novus Biologicals STRBP Protein
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    Cloud-Clone Corp. Proteins for STRBP

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR014720 dsRNA-bd_dom
     IPR006561 DZF

    Graphical View of Domain Structure for InterPro Entry Q96SI9

    ProtoNet protein and cluster: Q96SI9

    1 Blocks protein domain: IPB001159 Double-stranded RNA binding (DsRBD) domain

    UniProtKB/Swiss-Prot: STRBP_HUMAN, Q96SI9
    Similarity: Contains 2 DRBM (double-stranded RNA-binding) domains
    Similarity: Contains 1 DZF domain


    STRBP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: STRBP_HUMAN, Q96SI9
    Function: Involved in spermatogenesis and sperm function. Plays a role in regulation of cell growth. Binds to
    double-stranded DNA and RNA. Binds most efficiently to poly(I:C) RNA than to poly(dI:dC) DNA. Binds also to
    single-stranded poly(G) RNA. Binds non-specifically to the mRNA PRM1 3'-UTR and adenovirus VA RNA (By similarity)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003725double-stranded RNA binding IEA--
    GO:0003727single-stranded RNA binding IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    STRBP for ontologies           About GeneDecksing


    Phenotypes:
         6 MGI mutant phenotypes (inferred from 1 allele(MGI details for Strbp):
     behavior/neurological  endocrine/exocrine gland  growth/size/body  mortality/aging  nervous system 
     reproductive system 

    STRBP for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for STRBP
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for STRBP

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for STRBP
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for STRBP

    miRNA
    Products:
        
    miRTarBase miRNAs that target STRBP:
    hsa-mir-92b-3p (MIRT040658), hsa-mir-130b-3p (MIRT020149), hsa-mir-155-5p (MIRT020761), hsa-mir-21-5p (MIRT030912), hsa-mir-33a-5p (MIRT028221), hsa-mir-375 (MIRT019861)

    Block miRNA regulation of human, mouse, rat STRBP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate STRBP (see all 89):
    hsa-miR-124* hsa-miR-607 hsa-miR-300 hsa-miR-15a hsa-miR-146a hsa-miR-219-5p hsa-miR-409-5p hsa-miR-376a*
    SwitchGear 3'UTR luciferase reporter plasmidSTRBP 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for STRBP
    Predesigned siRNA for gene silencing in human, mouse, rat STRBP

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for STRBP (see all 11)
    OriGene ORF clones in mouse, rat for STRBP
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    GenScript: all cDNA clones in your preferred vector (see all 2): STRBP (NM_018387)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for STRBP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STRBP

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for STRBP
    Browse ESI BIO Cell Lines and PureStem Progenitors for STRBP 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STRBP


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    STRBP_HUMAN, Q96SI9: Cytoplasm (By similarity). Note=Microtubule-associated that localizes to the manchette in
    developing spermatids (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytoskeleton2
    cytosol2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IEA--
    GO:0015630microtubule cytoskeleton IEA--

    STRBP for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for STRBP
    Interactions:

        Search GeneGlobe Interaction Network for STRBP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for STRBP (Q96SI92, 3 ENSP000003213474) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RBPMSQ930622, 3, ENSP000003401764MINT-66074 I2D: score=5 STRING: ENSP00000340176
    THAP1Q9NVV92, 3, ENSP000002542504MINT-68310 I2D: score=5 STRING: ENSP00000254250
    EIF2AK2P195253, ENSP000002330574I2D: score=1 STRING: ENSP00000233057
    ATG101Q9BSB43I2D: score=1 
    CLN3Q132863I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006928cellular component movement IEA--
    GO:0007275multicellular organismal development IEA--
    GO:0007286spermatid development IEA--
    GO:0007638mechanosensory behavior IEA--

    STRBP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for STRBP



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for STRBP gene (2 alternative transcripts): 
    NM_001171137.1  NM_018387.4  

    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000530364 ENST00000478973 ENST00000471564 ENST00000496533 ENST00000348403
    ENST00000360998 ENST00000407982 ENST00000492885 ENST00000479114 ENST00000447404(uc004bnt.3 uc004bnu.3 uc004bns.3 uc004bnv.3)

    miRNA
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    Block miRNA regulation of human, mouse, rat STRBP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate STRBP (see all 89):
    hsa-miR-124* hsa-miR-607 hsa-miR-300 hsa-miR-15a hsa-miR-146a hsa-miR-219-5p hsa-miR-409-5p hsa-miR-376a*
    SwitchGear 3'UTR luciferase reporter plasmidSTRBP 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for STRBP
    Predesigned siRNA for gene silencing in human, mouse, rat STRBP
    Clone
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    OriGene ORF clones in mouse, rat for STRBP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): STRBP (NM_018387)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for STRBP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STRBP
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for STRBP
    OriGene qSTAR qPCR primer pairs in human, mouse for STRBP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat STRBP
      QuantiTect SYBR Green Assays in human, mouse, rat STRBP
      QuantiFast Probe-based Assays in human, mouse, rat STRBP

    Selected AceView cDNA sequences (see all 263):

    AA836810 BG315203 AI025833 BG113333 BM704833 CD299947 AW183150 BM728734 
    BM979986 BQ002726 AK123844 BQ440741 BU742655 BM904147 AW055268 AI090248 
    BU730467 BC034918 AK002169 BM666384 CR596677 CB135362 AK024285 BG107710 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for STRBP    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19
    SP1:        -                                                                                                                           
    SP2:                                                                                                                                    
    SP3:                                                                                                  -                                 
    SP4:                                                                                                  -                                 


    ECgene alternative splicing isoforms for STRBP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    STRBP expression in normal human tissues (normalized intensities)      STRBP embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACAAGCGCTT
    STRBP Expression
    About this image


    STRBP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
     
     Neurons
             GABAergic Amacrine Cells Inner Nuclear Layer
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
     
     Eye (Sensory Organs)
             GABAergic Amacrine Cells Inner Nuclear Layer
    STRBP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    STRBP Protein Expression
        Custom PCR Arrays for STRBP
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STRBP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for STRBP gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Strbp1 , 5 spermatid perinuclear RNA binding protein1, 5 94.05(n)1
    98.96(a)1
      2 (24.19 cM)5
    207441  NM_009261.31  NP_033287.21 
     374832285 
    chicken
    (Gallus gallus)
    Aves STRBP1 spermatid perinuclear RNA binding protein 85.44(n)
    92.25(a)
      417105  NM_001030680.1  NP_001025851.1 
    lizard
    (Anolis carolinensis)
    Reptilia STRBP6
    spermatid perinuclear RNA binding protein
    86(a)
    1 ↔ 1
    GL343751.1(150847-199077)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.159712 Transcribed sequence with weak similarity to protein more 77.61(n)    AL855766.2 
    zebrafish
    (Danio rerio)
    Actinopterygii strbp1 spermatid perinuclear RNA binding protein 70.73(n)
    79.1(a)
      557957  XM_701955.5  XP_707047.3 
    worm
    (Caenorhabditis elegans)
    Secernentea Y95B8A.86
    Protein Y95B8A.8 (Y95B8A.8) mRNA, complete cds
    14(a)
    1 → many
    I(853451-871947) WBGene00022388


    ENSEMBL Gene Tree for STRBP (if available)
    TreeFam Gene Tree for STRBP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for STRBP gene
    ZFR22  ILF22  ILF32  ZFR2  
    4 SIMAP similar genes for STRBP using alignment to 5 protein entries:     STRBP_HUMAN (see all proteins):
    DKFZp434P151    ILF3    ZFR    ZFR2

    STRBP for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for STRBP (see all 2368)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0356624
    A breast cancer sample4--see VAR_0356622 G R mis40--------
    rs1814305561,2
    --125883587(+) AAATAC/TAGCCT 3 -- ds50010--------
    rs1865256911,2
    --125883721(+) TGGGAA/GATAAA 3 -- ds50010--------
    rs1461862731,2
    --125883798(+) CGATAC/TTCACC 3 -- ds50010--------
    rs2003994771,2
    C--125883895(+) TTTTTG/TTTTTT 3 -- ds50010--------
    rs559742721,2
    C--125883896(+) TTTTG-/TTTTTT 3 -- ds50012Minor allele frequency- T:0.25NA CSA 4
    rs2021832751,2
    C--125883903(-) AAAAAA/GAAAAA 3 -- ut31 nc-transcript-variant0--------
    rs109858901,2
    C,F--125884052(+) TTACAC/TATACA 3 -- ut31 nc-transcript-variant5Minor allele frequency- T:0.32NA WA 244
    rs1909918491,2
    --125884075(+) ACTATG/TACCAA 3 -- ut31 nc-transcript-variant0--------
    rs601126641,2
    C--125884228(+) TTTCT-/ACACACA 3 -- ut31 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for STRBP (125871779 - 126030855 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for STRBP:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2658555CNV Deletion23128226
    nsv6706CNV Insertion18451855
    esv25223CNV Loss19812545
    nsv893826CNV Loss21882294
    esv1008345CNV Loss20482838
    nsv831717CNV Gain17160897
    nsv893825CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611138    OMIM disorders: --

    11 diseases for STRBP:    About MalaCards
    louping ill    murray valley encephalitis    opisthorchiasis    cryptorchidism
    encephalitis    down syndrome    breast and colorectal cancer    colorectal cancer
    multiple myeloma    myeloma    cerebritis


    STRBP for disorders           About GeneDecksing

    Genetic Association Database (GAD): STRBP

    Export disorders for STRBP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for STRBP gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with STRBP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    5. Mice deficient for spermatid perinuclear RNA-binding protein show neurologic, spermatogenic, and sperm morphological abnormalities. (PubMed id 11336498)1, 9 Pires-daSilva A....Gruss P. (Dev. Biol. 2001)
    6. Screening of LRRK2 interactants by yeast 2-hybrid analysis. (PubMed id 19001729)1, 9 Zheng X.Y....Zhang Z.H. (Zhong Nan Da Xue Xue Bao Yi Xue Ban 2008)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (J Proteomics 2012)
    9. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    10. Expression of STRBP mRNA in patients with cryptorchidism and Down's syndrome. (PubMed id 22391137)1 Salemi M....Calogero A.E. (J. Endocrinol. Invest. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55342 HGNC: 16462 AceView: STRBPandC9orf45 Ensembl:ENSG00000165209 euGenes: HUgn55342
    ECgene: STRBP H-InvDB: STRBP

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for STRBP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for STRBP gene:
    Search GeneIP for patents involving STRBP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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