Aliases for STRA13 Gene
External Ids for STRA13 Gene
Previous GeneCards Identifiers for STRA13 Gene
GeneCards Summary for STRA13 Gene
STRA13 (Stimulated By Retinoic Acid 13) is a Protein Coding gene. Diseases associated with STRA13 include congenital hypoplastic anemia and fanconi anemia, complementation group a. Among its related pathways are Cell Cycle, Mitotic and DNA Double-Strand Break Repair. GO annotations related to this gene include protein heterodimerization activity and double-stranded DNA binding.
UniProtKB/Swiss-Prot for STRA13 Gene
DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. Component of the APITD1/CENPS complex that is essential for the stable assembly of the outer kinetochore. Plays an important role in mitotic progression and chromosome segregation.