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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STRA13 Gene

protein-coding   GIFtS: 53
GCID: GC17M079977

Stimulated By Retinoic Acid 13

(Previous name: stimulated by retinoic acid 13 homolog (mouse))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Stimulated By Retinoic Acid 131 2     FANCM-Interacting Histone Fold Protein 22 3
Retinoic Acid-Inducible Gene D9 Protein Homolog2 3     Fanconi Anemia-Associated Polypeptide Of 10 KDa2 3
Stimulated By Retinoic Acid Gene 13 Protein Homolog2 3     Stimulated By Retinoic Acid 13 Homolog (Mouse)1
CENP-X2 3     D92
CENPX2 3     Centromere Protein X2
FAAP102 3     Stimulated By Retinoic Acid 13 Homolog2
MHF22 3     

External Ids:    HGNC: 114221   Entrez Gene: 2012542   Ensembl: ENSG000001696897   OMIM: 6151285   UniProtKB: A8MT693   

Export aliases for STRA13 gene to outside databases

Previous GC identifers: GC03U990073 GC17M080512 GC17M080655 GC17M077569 GC17M075376


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for STRA13 Gene: 
STRA13 (stimulated by retinoic acid 13) is a protein-coding gene. Diseases associated with STRA13 include anemia, and fanconi's anemia. GO annotations related to this gene include double-stranded DNA binding and DNA binding.

UniProtKB/Swiss-Prot: CENPX_HUMAN, A8MT69
Function: DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance.
Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions.
Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role
in kinetochore assembly. Component of the APITD1/CENPS complex that is essential for the stable assembly of the
outer kinetochore. Plays an important role in mitotic progression and chromosome segregation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010663.15  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STRA13 gene promoter:
         PPAR-gamma1   STAT1   AP-1   STAT3   STAT5A   PPAR-gamma2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTRA13 promoter sequence
   Search SABiosciences Chromatin IP Primers for STRA13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STRA13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.3   Ensembl cytogenetic band:  17q25.3   HGNC cytogenetic band: 17q25.3

STRA13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STRA13 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M079977:  view genomic region     (about GC identifiers)

Start:
79,976,578 bp from pter      End:
79,981,983 bp from pter
Size:
5,406 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CENPX_HUMAN, A8MT69 (See protein sequence)
Recommended Name: Centromere protein X  
Size: 81 amino acids; 8959 Da
Subunit: Belongs to the multisubunit FA complex composed of APITD1/CENPS, FANCA, FANCB, FANCC, FANCE, FANCF,
FANCG, FANCL/PHF9, FANCM, FAAP24 and STRA13/CENPX. Interacts with APITD1/CENPS, FANCM and FAAP24. Component of a
discrete APITD1/CENPS complex composed of at least APITD1/CENPS and STRA13/CENPX; this complex binds DNA. The
heterodimer composed of APITD1/CENPS and STRA13/CENPX can dimerize to form a heterotetramer. Component of a
heterotetrameric CENP-T-W-S-X complex composed of APITD1/CENPS, STRA13/CENPX, CENPT and CENPW
Subcellular location: Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Constitutively
localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis
4 PDB 3D structures from and Proteopedia for STRA13:
4DRA (3D)        4DRB (3D)        4E44 (3D)        4E45 (3D)    
Secondary accessions: O00281 O00282 Q96DD4 Q96F51
Alternative splicing: 3 isoforms:  A8MT69-1   A8MT69-2   A8MT69-3   

Explore the universe of human proteins at neXtProt for STRA13: NX_A8MT69

Explore proteomics data for STRA13 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_A8MT69

  • STRA13 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    STRA13 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001257935.1  NP_001257936.1  NP_659435.2  

    ENSEMBL proteins: 
     ENSP00000464024   ENSP00000463974   ENSP00000462015   ENSP00000302951   ENSP00000376168  
     ENSP00000464357  

    Human Recombinant Protein Products for STRA13: 
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    Novus Biologicals STRA13 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for STRA13 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0043240Fanconi anaemia nuclear complex IDA--
    GO:0071821FANCM-MHF complex IDA--

    STRA13 for ontologies           About GeneDecksing



    STRA13 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for STRA13


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR018552 CENP-S_centromere_X

    Graphical View of Domain Structure for InterPro Entry A8MT69

    ProtoNet protein and cluster: A8MT69

    UniProtKB/Swiss-Prot: CENPX_HUMAN, A8MT69
    Similarity: Belongs to the CENPX family


    STRA13 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CENPX_HUMAN, A8MT69
    Function: DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance.
    Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions.
    Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role
    in kinetochore assembly. Component of the APITD1/CENPS complex that is essential for the stable assembly of the
    outer kinetochore. Plays an important role in mitotic progression and chromosome segregation

         Genatlas biochemistry entry for STRA13:
    stimulated by retinoic acid 13,dysregulated in leukemogenesis and solid tumor,expressed (in mouse) in the
    neuroectoderm and also in a number of mesodermal and endodermal derivatives,functioning as a repressor of
    activated transcription and interacting with general factors of the basal transcription machinery, putatively
    involved in the control of differentiation of several cell lineages during mouse development

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IDA--
    GO:0003690contributes to double-stranded DNA binding IDA--
    GO:0005515protein binding IPI--
    GO:0046982protein heterodimerization activity ----
         
    STRA13 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for STRA13 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for STRA13

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for STRA13 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for STRA13 

    miRNA
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate STRA13:
    hsa-miR-2052 hsa-miR-7-2* hsa-miR-7-1* hsa-miR-146a hsa-miR-589 hsa-miR-758 hsa-miR-146b-5p
    SwitchGear 3'UTR luciferase reporter plasmidSTRA13 3' UTR sequence
    Inhib. RNA
    Products:
        
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STRA13


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for STRA13 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Fanconi anemia pathway
    Fanconi anemia pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for STRA13):
        Fanconi anemia pathway


    STRA13 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for STRA13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    5/17 Interacting proteins for STRA13 (A8MT691, 2, 3 ENSP000003029514) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APITD1Q8N2Z91, 2, 3EBI-5529694,EBI-5529649 MINT-8434649 MINT-8434669 MINT-8434686 MINT-8434303 I2D: score=1 
    FANCMQ8IYD82, 3, ENSP000002674304MINT-8434669 MINT-8434303 I2D: score=1 STRING: ENSP00000267430
    UBE2IP632793, ENSP000003248974I2D: score=3 STRING: ENSP00000324897
    FANCAO153603, ENSP000003739524I2D: score=1 STRING: ENSP00000373952
    FANCGO152873, ENSP000003679104I2D: score=1 STRING: ENSP00000367910
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000712resolution of meiotic recombination intermediates IMP--
    GO:0006281DNA repair IEA--
    GO:0007067mitosis IEA--
    GO:0031297replication fork processing IMP--
    GO:0031398positive regulation of protein ubiquitination TAS--

    STRA13 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STRA13 (CENPX)

    Search CenterWatch for drugs/clinical trials and news about STRA13 / CENPX

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for STRA13 gene (3 alternative transcripts): 
    NM_001271006.1  NM_001271007.1  NM_144998.3  

    Unigene Cluster for STRA13:

    Stimulated by retinoic acid 13
    Hs.37616  [show with all ESTs]
    Unigene Representative Sequence: BM906370
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000579520 ENST00000584600 ENST00000580435 ENST00000306704(uc002kdc.3 uc002kdd.3)
    ENST00000392359 ENST00000584514 ENST00000584347 ENST00000577379 ENST00000580090
    ENST00000583767 ENST00000585091
    miRNA
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate STRA13:
    hsa-miR-2052 hsa-miR-7-2* hsa-miR-7-1* hsa-miR-146a hsa-miR-589 hsa-miR-758 hsa-miR-146b-5p
    SwitchGear 3'UTR luciferase reporter plasmidSTRA13 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: STRA13 (NM_144998)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for STRA13
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STRA13
    Sirion Biotech Customized lentivirus for stable overexpression of STRA13 
                         Customized lentivirus expression plasmids for stable overexpression of STRA13 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat STRA13
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STRA13

    Additional mRNA sequence: 

    BC009571.1 BC011610.1 U95006.1 U95007.1 

    11 DOTS entries:

    DT.451769  DT.91913673  DT.92428685  DT.100685516  DT.92428683  DT.95116383  DT.120912404  DT.97859114 
    DT.75103430  DT.91639099  DT.95116369 

    24/196 AceView cDNA sequences (see all 196):

    BG683123 BE907815 BM792884 CB110749 AI352516 AW248627 AI078744 BM755961 
    AI369806 AA453750 BQ961030 BM423892 BQ678117 AI832453 BG764144 BE252274 
    BI260135 BM737678 BM685555 BE261863 CD671419 BG261193 CD368908 BC011610 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for STRA13 (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e · 7f
    SP1:                                      -                 -                                                   
    SP2:                                      -                                                                     
    SP3:                                      -                 -           -                                       
    SP4:                                                                                                            
    SP5:                                                        -                                                   


    ECgene alternative splicing isoforms for STRA13

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STRA13 expression in normal human tissues (normalized intensities)      STRA13 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGATATTCCC
    STRA13 Expression
    About this image


    STRA13 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 2 entries
             Primitive Syncytiotrophoblast Cells Chorion Frondosum
     
     Trophoblast (Extraembryonic Tissues)
             Extraembryonic Ectoderm Cells Extraembryonic Ectoderm

    See STRA13 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STRA13

    SOURCE GeneReport for Unigene cluster: Hs.37616
        SABiosciences Custom PCR Arrays for STRA13
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STRA13
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STRA13

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for STRA13 gene from 3/7 species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Stra131 , 5 stimulated by retinoic acid 131, 5 81.11(n)1
    86.67(a)1
      11 (84.45 cM)5
    208921  NM_016665.21  NP_057874.21 
     1207109425 
    lizard
    (Anolis carolinensis)
    Reptilia STRA136
    stimulated by retinoic acid 13
    46(a)
    1 ↔ 1
    2(118243857-118255004)
    zebrafish
    (Danio rerio)
    Actinopterygii stra136
    stimulated by retinoic acid 13 homolog (mouse)
    38(a)
    1 ↔ 1
    3(58639826-58643911)


    ENSEMBL Gene Tree for STRA13 (if available)
    TreeFam Gene Tree for STRA13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/89 SNPs in STRA13 are shown (see all 89)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1137086651,2
    C,F--79976128(+) CTGGGT/CGGGGC 3 -- int12Minor allele frequency- C:0.06CSA WA 119
    rs610622781,2
    C,F--79976181(+) GGGGGC/TGTGGC 3 -- int11Minor allele frequency- T:0.50WA 2
    rs1114524261,2
    C--79976206(+) CTGCAC/ACTCTC 3 -- int12Minor allele frequency- A:0.06CSA WA 119
    rs2017985481,2
    --79976237(+) GAGGC-/CTTCTTCA 3 -- cds10--------
    rs1442015711,2
    --79976297(+) CCTGCC/TTGTGA 3 -- int10--------
    rs1891439501,2
    --79976363(+) CCAACA/CCCTGG 3 -- int10--------
    rs757757381,2
    F--79976389(+) TCCCAG/AGCAGG 3 -- int11Minor allele frequency- A:0.03WA 118
    rs1816069371,2
    --79976407(+) ATGTAC/TGTGGT 3 -- int10--------
    rs1123009951,2
    C,F--79976414(+) TGGTCT/CGGGCT 3 -- int11Minor allele frequency- C:0.00CSA 1
    rs49694721,2
    C,F,A,H--79976425(-) AGGCGC/TTGTGG 3 -- int123Minor allele frequency- T:0.47NS EA NA WA CSA 2157

    HapMap Linkage Disequilibrium report for STRA13 (79976578 - 79981983 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/23 variations for STRA13 (see all 23):    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv909134CNV Loss21882294
    dgv3346n71CNV Loss21882294
    dgv3341n71CNV Loss21882294
    dgv3333n71CNV Loss21882294
    nsv909161CNV Loss21882294
    dgv3340n71CNV Loss21882294
    dgv3332n71CNV Loss21882294
    dgv3344n71CNV Loss21882294
    nsv457975CNV Loss19166990
    dgv3347n71CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 615128    OMIM disorders: --

    5 diseases for STRA13:    About MalaCards
    anemia    fanconi's anemia    intrahepatic cholangiocarcinoma    cholangiocarcinoma
    hypoxia

    1 disease from the University of Copenhagen DISEASES database for STRA13:
    Fanconi's anemia

    STRA13 for disorders           About GeneDecksing

    Genetic Association Database (GAD): STRA13
    Human Genome Epidemiology (HuGE) Navigator: STRA13 (8 documents)

    Export disorders for STRA13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STRA13 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with STRA13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of type 2 diabetes-associated combinat ion of SNPs using support vector machine. (PubMed id 20416077)1, 4 Ban H.J....Park K.J. (2010)
    2. The CENP-S complex is essential for the stable assembly of outer kinetochore structure. (PubMed id 19620631)1, 2 Amano M....Fukagawa T. (2009)
    3. E3, a hematopoietic-specific transcript directly regulated by the retinoic acid receptor alpha. (PubMed id 8839844)1, 3 Scott L.M....Collins S.J. (1996)
    4. A ubiquitin-binding protein, FAAP20, links RNF8-mediat ed ubiquitination to the Fanconi anemia DNA repair network. (PubMed id 22705371)1 Yan Z....Wang W. (2012)
    5. CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold. (PubMed id 22304917)2 Nishino T.... Fukagawa T. (2012)
    6. The structure of the FANCM-MHF complex reveals physica l features for functional assembly. (PubMed id 22510687)1 Tao Y....Teng M. (2012)
    7. MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM. (PubMed id 20347429)1 Singh T.R....Meetei A.R. (2010)
    8. Mouse Fem1b interacts with the Nkx3.1 homeoprotein and is required for proper male secondary sexual development. (PubMed id 18816836)1 Wang X....Shen M.M. (2008)
    9. Stra13 is induced by genotoxic stress and regulates i onizing-radiation-induced apoptosis. (PubMed id 17347673)1 Thin T.H....Taneja R. (2007)
    10. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 201254 HGNC: 11422 AceView: STRA13 Ensembl:ENSG00000169689 euGenes: HUgn201254
    ECgene: STRA13 Kegg: 201254 H-InvDB: STRA13

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for STRA13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for STRA13 gene:
    Search GeneIP for patents involving STRA13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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