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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STRA13 Gene

protein-coding   GIFtS: 49
GCID: GC17M079977

stimulated by retinoic acid 13

(Previous names: stimulated by retinoic acid 13, stimulated by retinoic...)
 Explore 5 diseases affiliated with
STRA13 via our new
 Human Malady Compendium 
Biological research products
for STRA13
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Stimulated By Retinoic Acid 131 2     MGC144801
FAAP101 2 3     Stimulated By Retinoic Acid 13 Homolog (Mouse)1
MHF21 2 3     Centromere Protein X2
Retinoic Acid-Inducible Gene D9 Protein Homolog2 3     Stimulated By Retinoic Acid 13 Homolog2
Stimulated By Retinoic Acid Gene 13 Protein Homolog2 3     CENPX3
CENP-X2 3     BHLHE405
FANCM-Interacting Histone Fold Protein 22 3     DEC15
Fanconi Anemia-Associated Polypeptide Of 10 KDa2 3     HLHB25

External Ids:    HGNC: 114221   Entrez Gene: 2012542   Ensembl: ENSG000001696897   OMIM: 6042565   UniProtKB: A8MT693   

Export aliases for STRA13 gene to outside databases

Previous GC identifers: GC03U990073 GC17M080512 GC17M080655 GC17M077569 GC17M075376


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CENPX_HUMAN, A8MT69
Function: DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance. Recruited
to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions. Component of
the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore
assembly. Component of the APITD1/CENPS complex that is essential for the stable assembly of the outer kinetochore.
Plays an important role in mitotic progression and chromosome segregation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010663.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STRA13 gene promoter:
         PPAR-gamma1   STAT1   AP-1   STAT3   STAT5A   PPAR-gamma2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTRA13 promoter sequence
   Search SABiosciences Chromatin IP Primers for STRA13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STRA13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.3   Ensembl cytogenetic band:  17q25.3   HGNC cytogenetic band: 17q25.3

STRA13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STRA13 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M079977:  view genomic region     (about GC identifiers)

Start:
79,976,578 bp from pter      End:
79,981,983 bp from pter
Size:
5,406 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CENPX_HUMAN, A8MT69 (See protein sequence)
Recommended Name: Centromere protein X  
Size: 81 amino acids; 8959 Da
Subunit: Belongs to the multisubunit FA complex composed of APITD1/CENPS, FANCA, FANCB, FANCC, FANCE, FANCF, FANCG,
FANCL/PHF9, FANCM, FAAP24 and STRA13/CENPX. Interacts with APITD1/CENPS, FANCM and FAAP24. Component of a discrete
APITD1/CENPS complex composed of at least APITD1/CENPS and STRA13/CENPX; this complex binds DNA. The heterodimer
composed of APITD1/CENPS and STRA13/CENPX can dimerize to form a heterotetramer. Component of a heterotetrameric
CENP-T-W-S-X complex composed of APITD1/CENPS, STRA13/CENPX, CENPT and CENPW
Subcellular location: Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Constitutively
localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis
2 PDB 3D structures from and Proteopedia for STRA13:
4DRA (3D)        4DRB (3D)    
Secondary accessions: O00281 O00282 Q96DD4 Q96F51
Alternative splicing: 3 isoforms:  A8MT69-1   A8MT69-2   A8MT69-3   

Explore the universe of human proteins at neXtProt for STRA13: NX_A8MT69

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_A8MT69

  • STRA13 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001257935.1  NP_001257936.1  NP_659435.2  

    ENSEMBL proteins: 
     ENSP00000464024   ENSP00000463974   ENSP00000462015   ENSP00000302951   ENSP00000376168  
     ENSP00000464357  

    Human Recombinant Protein Products: 
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    Novus Biologicals STRA13 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for STRA13

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0043240Fanconi anaemia nuclear complex IDA--
    GO:0071821FANCM-MHF complex IDA--


    STRA13 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    STRA13 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR018552 CENP-S_centromere_X

    Graphical View of Domain Structure for InterPro Entry A8MT69

    ProtoNet protein and cluster: A8MT69

    UniProtKB/Swiss-Prot: CENPX_HUMAN, A8MT69
    Similarity: Belongs to the CENPX family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CENPX_HUMAN, A8MT69
    Function: DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance. Recruited
    to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions. Component of
    the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore
    assembly. Component of the APITD1/CENPS complex that is essential for the stable assembly of the outer kinetochore.
    Plays an important role in mitotic progression and chromosome segregation

         Genatlas biochemistry entry for STRA13:
    stimulated by retinoic acid 13,dysregulated in leukemogenesis and solid tumor,expressed (in mouse) in the neuroectoderm
    and also in a number of mesodermal and endodermal derivatives,functioning as a repressor of activated transcription
    and interacting with general factors of the basal transcription machinery, putatively involved in the control of
    differentiation of several cell lineages during mouse development

    miRNA
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate STRA13:
    hsa-miR-2052 hsa-miR-7-2* hsa-miR-7-1* hsa-miR-146a hsa-miR-589 hsa-miR-758 hsa-miR-146b-5p
    SwitchGear 3'UTR luciferase reporter plasmidSTRA13 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: STRA13
    OriGene siRNA: STRA13
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat STRA13

    Gene Editing
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    Clone
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STRA13 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STRA13

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IDA--
    GO:0003690contributes to double-stranded DNA binding IDA--
    GO:0005515protein binding IPI--


    STRA13 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for STRA13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    5/17 Interacting proteins for STRA13 (A8MT691, 3 ENSP000003029514) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APITD1Q8N2Z91, 3EBI-5529694,EBI-5529649 I2D: score=1 
    UBE2IP632793, ENSP000003248974I2D: score=3 STRING: ENSP00000324897
    FANCAO153603, ENSP000003739524I2D: score=1 STRING: ENSP00000373952
    FANCGO152873, ENSP000003679104I2D: score=1 STRING: ENSP00000367910
    TP53P046373, ENSP000002693054I2D: score=1 STRING: ENSP00000269305
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000712resolution of meiotic recombination intermediates IMP--
    GO:0006281DNA repair IEA--
    GO:0007067mitosis IEA--
    GO:0031297replication fork processing IMP--
    GO:0031398positive regulation of protein ubiquitination TAS--


    STRA13 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STRA13
    Search CenterWatch for drugs/clinical trials and news about STRA13 / CENPX 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for STRA13 gene (3 alternative transcripts): 
    NM_001271006.1  NM_001271007.1  NM_144998.3  

    Unigene Cluster for STRA13:

    Stimulated by retinoic acid 13 homolog (mouse)
    Hs.37616  [show with all ESTs]
    Unigene Representative Sequence: BM906370
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000579520 ENST00000584600 ENST00000580435 ENST00000306704(uc002kdc.3 uc002kdd.3)
    ENST00000392359 ENST00000584514 ENST00000584347 ENST00000577379 ENST00000580090
    ENST00000583767 ENST00000585091

    miRNA
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate STRA13:
    hsa-miR-2052 hsa-miR-7-2* hsa-miR-7-1* hsa-miR-146a hsa-miR-589 hsa-miR-758 hsa-miR-146b-5p
    SwitchGear 3'UTR luciferase reporter plasmidSTRA13 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STRA13 (see all 4)
    OriGene shRNA RFP: STRA13
    OriGene siRNA: STRA13
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat STRA13
    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for STRA13 (see all 2)
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    Additional cDNA sequence: 

    BC009571.1 BC011610.1 U95006.1 U95007.1 

    11 DOTS entries:

    DT.451769  DT.91913673  DT.92428685  DT.100685516  DT.92428683  DT.95116383  DT.120912404  DT.97859114 
    DT.75103430  DT.91639099  DT.95116369 

    24/196 AceView cDNA sequences (see all 196):

    BU184907 CB157777 AW248627 BI333047 AI918037 CD368908 BM476952 CB123767 
    BM423892 BU507436 BM685555 BI260135 CB107238 BM792884 BM737678 CB163757 
    AI186570 AI206003 BE907815 BE252274 BG261193 BG683123 AI369806 AA453750 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for STRA13 (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e · 7f
    SP1:                                      -                 -                                                   
    SP2:                                      -                                                                     
    SP3:                                      -                 -           -                                       
    SP4:                                                                                                            
    SP5:                                                        -                                                   


    ECgene alternative splicing isoforms for STRA13

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STRA13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CGATATTCCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    STRA13 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    PlacentaChorion FrondosumPrimitive Syncytiotrophoblast CellsExtraembryonic Tissues, Placenta
    PlacentaColumn Cytotrophoblast LayerColumn Cytotrophoblast CellsExtraembryonic Tissues, Placenta
    TrophoblastExtraembryonic EctodermExtraembryonic Ectoderm CellsExtraembryonic Tissues, Placenta
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See STRA13 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STRA13

    SOURCE GeneReport for Unigene cluster: Hs.37616
        SABiosciences Custom PCR Arrays for STRA13
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STRA13

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for STRA13 gene from 2/5 species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Stra131 , 5 stimulated by retinoic acid 131, 5 81.11(n)1
    86.67(a)1
      11 (84.45 cM)5
    208921  NM_016665.21  NP_057874.21 
     1207109425 
    zebrafish
    (Danio rerio)
    Actinopterygii stra136
    stimulated by retinoic acid 13 homolog (mouse)
    38(a)
    1 ↔ 1
    3(58639826-58643911)


    ENSEMBL Gene Tree for STRA13 (if available)
    TreeFam Gene Tree for STRA13 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/122 NCBI SNPs in STRA13 are shown (see all 122    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1137086651,2
    --79976128(+) CTGGGT/CGGGGC 3 -- int12Minor allele frequency- C:0.06CSA WA 119
    rs610622781,2
    C,--79976181(+) GGGGGC/TGTGGC 3 -- int11Minor allele frequency- T:0.50WA 2
    rs1114524261,2
    C,--79976206(+) CTGCAC/ACTCTC 3 -- int12Minor allele frequency- A:0.06CSA WA 119
    rs2017985481,2
    --79976237(+) GAGGC-/CTTCTTCA 3 -- int10--------
    rs1442015711,2
    --79976297(+) CCTGCC/TTGTGA 3 -- int10--------
    rs1891439501,2
    --79976363(+) CCAACA/CCCTGG 3 -- int10--------
    rs757757381,2
    F,--79976389(+) TCCCAG/AGCAGG 3 -- int11Minor allele frequency- A:0.03WA 118
    rs1816069371,2
    --79976407(+) ATGTAC/TGTGGT 3 -- int10--------
    rs1123009951,2
    --79976414(+) TGGTCT/CGGGCT 3 -- int11Minor allele frequency- C:0.00CSA 1
    rs49694721,2
    C,F,A,H,--79976425(-) AGGCGC/TTGTGG 3 -- int123Minor allele frequency- T:0.47NS EA NA WA CSA 2157

    HapMap Linkage Disequilibrium report for STRA13 (79976578 - 79981983 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for STRA13
         2 CNVs: 30036 73078

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing STRA13
    DNA2.0 Custom Variant and Variant Library Synthesis for STRA13

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    STRA13 for disorders           About GeneDecksing

    OMIM gene information: 604256    OMIM disorders: --

    5 diseases for STRA13:    About MalaCards
    fanconi's anemia    anemia    intrahepatic cholangiocarcinoma    cholangiocarcinoma
    hypoxia

    1 disease from the University of Copenhagen DISEASES database for STRA13:
    Fanconi's anemia
    Human Genome Epidemiology (HuGE) Navigator: STRA13 (8 documents)

    Export disorders for STRA13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STRA13 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with STRA13)
        Utopia: connect your pdf to the dynamic
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    1. The CENP-S complex is essential for the stable assembly of outer kinetochore structure. (PubMed id 19620631)1, 2 Amano M....Fukagawa T. (2009)
    2. E3, a hematopoietic-specific transcript directly regulated by the retinoic acid receptor alpha. (PubMed id 8839844)1, 3 Scott L.M....Collins S.J. (1996)
    3. Clonal B cells of HCV-associated mixed cryoglobulinemi a patients contain exhausted marginal zone-like and CD21 low cells overexpressin g Stra13. (PubMed id 22678901)1 Visentini M....Fiorilli M. (2012)
    4. The structure of the FANCM-MHF complex reveals physica l features for functional assembly. (PubMed id 22510687)1 Tao Y....Teng M. (2012)
    5. A ubiquitin-binding protein, FAAP20, links RNF8-mediat ed ubiquitination to the Fanconi anemia DNA repair network. (PubMed id 22705371)1 Yan Z....Wang W. (2012)
    6. CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold. (PubMed id 22304917)2 Nishino T.... Fukagawa T. (2012)
    7. SUMO modification of Stra13 is required for repression of cyclin D1 expression and cellular growth arrest. (PubMed id 22905217)1 Wang Y....Taneja R. (2012)
    8. Identification of type 2 diabetes-associated combinat ion of SNPs using support vector machine. (PubMed id 20416077)1 Ban H.J....Park K.J. (2010)
    9. MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM. (PubMed id 20347429)1 Singh T.R....Meetei A.R. (2010)
    10. Stra13 regulates oxidative stress mediated skeletal m uscle degeneration. (PubMed id 19679564)1 Vercherat C....Taneja R. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 201254 HGNC: 11422 AceView: STRA13 Ensembl:ENSG00000169689 euGenes: HUgn201254
    ECgene: STRA13 H-InvDB: STRA13

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for STRA13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for STRA13 gene:
    Search GeneIP for patents involving STRA13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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