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Aliases for STPG3 Gene

Aliases for STPG3 Gene

  • Sperm-Tail PG-Rich Repeat Containing 3 2 3 5
  • Sperm-Tail PG-Rich Repeat-Containing Protein 3 3 4
  • C9orf173 3 4
  • Chromosome 9 Open Reading Frame 173 2
  • Protein STPG3 3

External Ids for STPG3 Gene

Previous HGNC Symbols for STPG3 Gene

  • C9orf173

Summaries for STPG3 Gene

GeneCards Summary for STPG3 Gene

STPG3 (Sperm-Tail PG-Rich Repeat Containing 3) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STPG3 Gene

Genomics for STPG3 Gene

Regulatory Elements for STPG3 Gene

Enhancers for STPG3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F136725 1.2 ENCODE 9.7 -523.4 -523393 4.1 PKNOX1 ARNT CREB3L1 MLX WRNIP1 ARID4B SIN3A DMAP1 YY1 ZNF207 SNHG7 LCN8 LCN6 FAM166A NDOR1 CCDC183-AS1 STPG3 ENSG00000281808 GC09M136747 SNORA17A
GH09F137267 1.2 Ensembl ENCODE 6.3 +18.0 18021 2.3 HDGF PKNOX1 ARNT WRNIP1 ZNF48 NCOA1 KAT8 MEF2D SMARCA4 NBN NELFB STPG3 TOR4A
GH09F137327 0.7 ENCODE 9.9 +77.2 77204 0.2 KLF1 RNF2 KLF17 JUNB EP300 ZNF324 ZFHX2 CBX8 SMARCA4 AEBP2 FAM166A STPG3 CCDC183-AS1 GC09M137332 NRARP
GH09F137417 0.9 FANTOM5 Ensembl 2.9 +166.9 166861 1.4 MXI1 USF1 POLR2A USF2 MAX MYC KDM6A FAM166A STPG3 ABCA2 LCNL1 EXD3 GC09M137332
GH09F137569 0.5 FANTOM5 3.4 +318.5 318540 0.4 ZFHX2 ZNF366 ZNF670 EGR2 EHMT1 FAM166A STPG3 DPH7 MRPL41
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around STPG3 on UCSC Golden Path with GeneCards custom track

Genomic Location for STPG3 Gene

Chromosome:
9
Start:
137,250,840 bp from pter
End:
137,253,483 bp from pter
Size:
2,644 bases
Orientation:
Plus strand

Genomic View for STPG3 Gene

Genes around STPG3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
STPG3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for STPG3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STPG3 Gene

Proteins for STPG3 Gene

  • Protein details for STPG3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N7X2-STPG3_HUMAN
    Recommended name:
    Protein STPG3
    Protein Accession:
    Q8N7X2
    Secondary Accessions:
    • A2RU24
    • B7ZM72
    • B7ZM76
    • Q8NEA3

    Protein attributes for STPG3 Gene

    Size:
    389 amino acids
    Molecular mass:
    42877 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for STPG3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for STPG3 Gene

Post-translational modifications for STPG3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for STPG3 Gene

Domains & Families for STPG3 Gene

Protein Domains for STPG3 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with STPG3: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for STPG3 Gene

Function for STPG3 Gene

genes like me logo Genes that share phenotypes with STPG3: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for STPG3 Gene

Localization for STPG3 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for STPG3 gene
Compartment Confidence
nucleus 2
cytosol 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for STPG3 Gene

Pathways & Interactions for STPG3 Gene

SuperPathways for STPG3 Gene

No Data Available

Interacting Proteins for STPG3 Gene

Selected Interacting proteins: Q8N7X2-STPG3_HUMAN for STPG3 Gene via IID

Symbol External ID(s) Details
LONP1

Gene Ontology (GO) - Biological Process for STPG3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for STPG3 Gene

Transcripts for STPG3 Gene

mRNA/cDNA for STPG3 Gene

(6) REFSEQ mRNAs :
(10) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for STPG3 Gene

Chromosome 9 open reading frame 173:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for STPG3 Gene

No ASD Table

Relevant External Links for STPG3 Gene

GeneLoc Exon Structure for
STPG3
ECgene alternative splicing isoforms for
STPG3

Expression for STPG3 Gene

NURSA nuclear receptor signaling pathways regulating expression of STPG3 Gene:

STPG3

SOURCE GeneReport for Unigene cluster for STPG3 Gene:

Hs.372640
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for STPG3 Gene

Orthologs for STPG3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for STPG3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C9H9orf173 34
  • 99.03 (n)
C9orf173 35
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4933433C11Rik 34 35
  • 74.75 (n)
Stpg3 16
rat
(Rattus norvegicus)
Mammalia LOC499746 34
  • 73.93 (n)
dog
(Canis familiaris)
Mammalia C9orf173 35
  • 59 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C9orf173 35
  • 40 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 18 (a)
OneToOne
Species where no ortholog for STPG3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for STPG3 Gene

ENSEMBL:
Gene Tree for STPG3 (if available)
TreeFam:
Gene Tree for STPG3 (if available)

Paralogs for STPG3 Gene

No data available for Paralogs for STPG3 Gene

Variants for STPG3 Gene

Sequence variations from dbSNP and Humsavar for STPG3 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs111436143 -- 137,249,473(+) GTAGG(G/T)CCTTT intron-variant, upstream-variant-2KB
rs111927058 -- 137,252,441(+) GAGGG(C/T)GGTGG nc-transcript-variant, upstream-variant-2KB, reference, synonymous-codon
rs111972181 -- 137,250,626(+) CTTGC(A/T)CACAC nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs112089378 -- 137,252,644(+) GCCCG(A/T)CTCCT intron-variant, upstream-variant-2KB
rs112228488 -- 137,253,752(+) TTGCC(A/G)AGCCA intron-variant, downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for STPG3 Gene

Variant ID Type Subtype PubMed ID
nsv951207 CNV deletion 24416366
nsv524322 CNV loss 19592680
nsv1161918 CNV duplication 26073780
esv2422220 CNV deletion 17116639
dgv13011n54 CNV loss 21841781
dgv13009n54 CNV loss 21841781

Variation tolerance for STPG3 Gene

Residual Variation Intolerance Score: 84.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.34; 63.16% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for STPG3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
STPG3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for STPG3 Gene

Disorders for STPG3 Gene

Relevant External Links for STPG3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
STPG3
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
STPG3

No disorders were found for STPG3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for STPG3 Gene

Publications for STPG3 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  3. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for STPG3 Gene

Sources for STPG3 Gene

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