STPG2 Gene
protein-coding GIFtS: 32
GCID: GC04M098105
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sperm-tail PG-rich repeat containing 2(Previous name: chromosome 4 open reading frame 37 )
(Previous symbol: C4orf37)
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Aliases
for STPG2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Sperm-Tail PG-Rich Repeat Containing 21 2 | | C4orf371 2 3 | | MGC464961 | | Chromosome 4 Open Reading Frame 371 | | Sperm-Tail PG-Rich Repeat-Containing Protein 22 |
Export aliases for STPG2 gene to outside databases |
Summaries
for STPG2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for STPG2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for STPG2
Other transcription factors
Search SABiosciences Chromatin IP Primers for STPG2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STPG2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q22.3-q23 Ensembl cytogenetic band: 4q23 HGNC cytogenetic band: 4q22.3-q23STPG2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M098105: view genomic region
(about GC identifiers)
Start:
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98,105,244 bp from pter |
End:
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99,064,391 bp from pter |
Size:
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959,148 bases |
Orientation:
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minus strand |
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Proteins
for STPG2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: STPG2_HUMAN, Q8N412 (See
protein sequence)Recommended Name: Sperm-tail PG-rich repeat-containing protein 2 Size: 459 amino acids; 50660 DaExplore the universe of human proteins at neXtProt for STPG2: NX_Q8N412
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N412
STPG2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_777612.1
ENSEMBL proteins: ENSP00000428346 ENSP00000295268
Human Recombinant Protein Products for STPG2:
STPG2 Antibody Products:
Assay Products for STPG2: |
Protein
Domains /
Families
for STPG2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
STPG2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8N412ProtoNet protein and cluster: Q8N412 UniProtKB/Swiss-Prot: STPG2_HUMAN, Q8N412Similarity: Contains 9 STPGR (Sperm-tail PG-rich) repeats |
Function
for STPG2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for STPG2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for STPG2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for STPG2 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for STPG2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STPG2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STPG2 |
|
Pathways & Interactions
for STPG2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for STPG2
|
Drugs & Compounds
for STPG2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for STPG2
Search CenterWatch for drugs/clinical trials and news about STPG2
|
Transcripts
for STPG2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for STPG2 gene: NM_174952.2 Unigene Cluster for STPG2: Sperm-tail PG-rich repeat containing 2 Hs.680226 [show with all ESTs]Unigene Representative Sequence: BX6483053 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000522676 ENST00000506482 ENST00000295268(uc003htt.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for STPG2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for STPG2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for STPG2 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for STPG2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STPG2 |
Additional cDNA sequence: BC036870.1 BX648305.1 2 DOTS entries: DT.99932648 DT.91976114 4 AceView cDNA sequences: BX648305 BG211405 NM_174952 BC036870
GeneLoc Exon Structure
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Expression
for STPG2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
See STPG2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for STPG2
SOURCE GeneReport for Unigene cluster: Hs.680226
SABiosciences Custom PCR Arrays for STPG2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for STPG2
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat STPG2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat STPG2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STPG2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STPG2 |
Orthologs
for STPG2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for STPG2 gene from 4/16 species (see all 16) About this table
ENSEMBL Gene Tree for STPG2 (if available)
TreeFam Gene Tree for STPG2 (if available) |
Paralogs
for STPG2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for STPG2 gene
STPG2 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for STPG2
PGOHUM00000234950
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Genomic Variants
for STPG2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 4 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for STPG2 (98105244 - 98355244 bp, first 250kb of STPG2)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for STPG2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing STPG2 |
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Disorders
/ Diseases
for STPG2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for STPG2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for STPG2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with STPG2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Exceptional complex chromosomal rearrangement and micr odeletions at the 4q22.3q23 and 14q31.1q31.3 regions in a patient with azoosperm ia. (PubMed id 23031811)1, 3 Yakut S....Luleci G. (2013)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for STPG2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing STPG2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing STPG2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing STPG2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for STPG2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for STPG2 gene:
Search GeneIP for patents involving STPG2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for STPG2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for STPG2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STPG2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for STPG2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for STPG2 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for STPG2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for STPG2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for STPG2 | | OriGene Custom Protein Services for STPG2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat STPG2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing STPG2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STPG2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat STPG2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STPG2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat STPG2 |
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| | | | Search Tocris compounds for STPG2 |
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 | | | STPG2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STPG2 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for STPG2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STPG2 |
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