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Aliases for STPG1 Gene

Aliases for STPG1 Gene

  • Sperm-Tail PG-Rich Repeat Containing 1 2 3
  • Sperm-Tail PG-Rich Repeat-Containing Protein 1 3 4
  • O6-Methylguanine-Induced Apoptosis 2 2 3
  • C1orf201 3 4
  • MAPO2 3 4
  • O(6)-Methylguanine-Induced Apoptosis 2 3
  • Chromosome 1 Open Reading Frame 201 2
  • UPF0490 Protein C1orf201 3

External Ids for STPG1 Gene

Previous Symbols for STPG1 Gene

  • C1orf201

Summaries for STPG1 Gene

GeneCards Summary for STPG1 Gene

STPG1 (Sperm-Tail PG-Rich Repeat Containing 1) is a Protein Coding gene.

UniProtKB/Swiss-Prot for STPG1 Gene

  • May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STPG1 Gene

Genomics for STPG1 Gene

Genomic Location for STPG1 Gene

Start:
24,356,999 bp from pter
End:
24,416,934 bp from pter
Size:
59,936 bases
Orientation:
Minus strand

Genomic View for STPG1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for STPG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STPG1 Gene

No data available for Regulatory Elements for STPG1 Gene

Proteins for STPG1 Gene

  • Protein details for STPG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TH74-STPG1_HUMAN
    Recommended name:
    O(6)-methylguanine-induced apoptosis 2
    Protein Accession:
    Q5TH74
    Secondary Accessions:
    • Q49AP0
    • Q6P3R4
    • Q86VU9
    • Q8WVQ3

    Protein attributes for STPG1 Gene

    Size:
    334 amino acids
    Molecular mass:
    36786 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for STPG1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for STPG1 Gene

Proteomics data for STPG1 Gene at MOPED

Post-translational modifications for STPG1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for STPG1 Gene

Domains for STPG1 Gene

Protein Domains for STPG1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

STPG1_HUMAN
Family:
  • Belongs to the STPG1 family.:
    • Q5TH74
Similarity:
  • Contains 7 STPGR (Sperm-tail PG-rich) repeats.:
    • Q5TH74
genes like me logo Genes that share domains with STPG1: view

No data available for Gene Families for STPG1 Gene

Function for STPG1 Gene

Molecular function for STPG1 Gene

UniProtKB/Swiss-Prot Function: May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine.

miRNA for STPG1 Gene

miRTarBase miRNAs that target STPG1

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for STPG1 Gene

Localization for STPG1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for STPG1 Gene

Cytoplasm. Nucleus.

Gene Ontology (GO) - Cellular Components for STPG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with STPG1: view

Pathways for STPG1 Gene

SuperPathways for STPG1 Gene

No Data Available

Interacting Proteins for STPG1 Gene

Gene Ontology (GO) - Biological Process for STPG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006915 apoptotic process IEA --
genes like me logo Genes that share ontologies with STPG1: view

No data available for Pathways by source for STPG1 Gene

Transcripts for STPG1 Gene

Unigene Clusters for STPG1 Gene

Sperm-tail PG-rich repeat containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for STPG1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12a · 12b
SP1: - -
SP2: - - - -
SP3: -
SP4: -
SP5:

Relevant External Links for STPG1 Gene

GeneLoc Exon Structure for
STPG1
ECgene alternative splicing isoforms for
STPG1

Expression for STPG1 Gene

mRNA expression in normal human tissues for STPG1 Gene

mRNA differential expression in normal tissues according to GTEx for STPG1 Gene

This gene is overexpressed in Testis (5.1).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for STPG1 Gene

SOURCE GeneReport for Unigene cluster for STPG1 Gene Hs.403187

genes like me logo Genes that share expressions with STPG1: view

Orthologs for STPG1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for STPG1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia STPG1 36
  • 99.3 (n)
  • 99.4 (a)
STPG1 37
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia STPG1 36
  • 83.83 (n)
  • 81.14 (a)
STPG1 37
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia STPG1 36
  • 84.33 (n)
  • 79.94 (a)
STPG1 37
  • 79 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Stpg1 36
  • 75.48 (n)
  • 71.77 (a)
Stpg1 16
Stpg1 37
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia STPG1 37
  • 58 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia STPG1 37
  • 54 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Stpg1 36
  • 76.22 (n)
  • 72.56 (a)
lizard
(Anolis carolinensis)
Reptilia STPG1 37
  • 43 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia stpg1 36
  • 56.88 (n)
  • 51.82 (a)
zebrafish
(Danio rerio)
Actinopterygii stpg1 36
  • 50.69 (n)
  • 40.58 (a)
stpg1 37
  • 39 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 35 (a)
OneToOne
Species with no ortholog for STPG1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for STPG1 Gene

ENSEMBL:
Gene Tree for STPG1 (if available)
TreeFam:
Gene Tree for STPG1 (if available)

Paralogs for STPG1 Gene

No data available for Paralogs for STPG1 Gene

Variants for STPG1 Gene

Sequence variations from dbSNP and Humsavar for STPG1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs475397 -- 24,391,107(+) ataag(C/G)caccg intron-variant
rs489998 -- 24,397,495(-) ggctg(C/T)tgacc intron-variant
rs497071 -- 24,387,343(-) AAATG(A/C)CCCCA intron-variant
rs497823 -- 24,393,856(+) gatgg(C/T)cccca intron-variant
rs498939 -- 24,393,201(+) CTCTA(A/G)TAAGT intron-variant

Relevant External Links for STPG1 Gene

HapMap Linkage Disequilibrium report
STPG1

No data available for Structural Variations from Database of Genomic Variants (DGV) for STPG1 Gene

Disorders for STPG1 Gene

No disorders were found for STPG1 Gene.

No data available for UniProtKB/Swiss-Prot for STPG1 Gene

Publications for STPG1 Gene

  1. The identification of a novel gene, MAPO2, that is involved in the induction of apoptosis triggered by O(6)-methylguanine. (PMID: 23028632) Fujikane R. … Hidaka M. (PLoS ONE 2012) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4
  4. The consensus coding sequences of human breast and colorectal cancers. (PMID: 16959974) Sjoeblom T. … Velculescu V.E. (Science 2006) 4
  5. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PMID: 19690332) Mayya V. … Han D.K. (Sci. Signal. 2009) 4

Products for STPG1 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate STPG1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for STPG1
    • Block miRNA regulation of STPG1 using miScript Target Protectors

    Sources for STPG1 Gene

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