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Aliases for STPG1 Gene

Aliases for STPG1 Gene

  • Sperm-Tail PG-Rich Repeat Containing 1 2 3
  • Sperm-Tail PG-Rich Repeat-Containing Protein 1 3 4
  • O6-Methylguanine-Induced Apoptosis 2 2 3
  • C1orf201 3 4
  • MAPO2 3 4
  • Chromosome 1 Open Reading Frame 201 2
  • UPF0490 Protein C1orf201 3

External Ids for STPG1 Gene

Previous HGNC Symbols for STPG1 Gene

  • C1orf201

Previous GeneCards Identifiers for STPG1 Gene

  • GC01M024684
  • GC01M024685

Summaries for STPG1 Gene

GeneCards Summary for STPG1 Gene

STPG1 (Sperm-Tail PG-Rich Repeat Containing 1) is a Protein Coding gene.

UniProtKB/Swiss-Prot for STPG1 Gene

  • May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STPG1 Gene

Genomics for STPG1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for STPG1 Gene

Chromosome:
1
Start:
24,356,999 bp from pter
End:
24,416,934 bp from pter
Size:
59,936 bases
Orientation:
Minus strand

Genomic View for STPG1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for STPG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STPG1 Gene

No data available for Regulatory Elements for STPG1 Gene

Proteins for STPG1 Gene

  • Protein details for STPG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TH74-STPG1_HUMAN
    Recommended name:
    O(6)-methylguanine-induced apoptosis 2
    Protein Accession:
    Q5TH74
    Secondary Accessions:
    • Q49AP0
    • Q6P3R4
    • Q86VU9
    • Q8WVQ3

    Protein attributes for STPG1 Gene

    Size:
    334 amino acids
    Molecular mass:
    36786 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for STPG1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for STPG1 Gene

Proteomics data for STPG1 Gene at MOPED

Post-translational modifications for STPG1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for STPG1 Gene

Domains & Families for STPG1 Gene

Protein Domains for STPG1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for STPG1 Gene

Graphical View of Domain Structure for InterPro Entry

Q5TH74

UniProtKB/Swiss-Prot:

STPG1_HUMAN :
  • Belongs to the STPG1 family.
  • Contains 7 STPGR (Sperm-tail PG-rich) repeats.
Family:
  • Belongs to the STPG1 family.
Similarity:
  • Contains 7 STPGR (Sperm-tail PG-rich) repeats.
genes like me logo Genes that share domains with STPG1: view

No data available for Gene Families for STPG1 Gene

Function for STPG1 Gene

Molecular function for STPG1 Gene

UniProtKB/Swiss-Prot Function:
May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine.

Phenotypes for STPG1 Gene

GenomeRNAi human phenotypes for STPG1:
genes like me logo Genes that share phenotypes with STPG1: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for STPG1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for STPG1 Gene

Localization for STPG1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for STPG1 Gene

Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for STPG1 Gene COMPARTMENTS Subcellular localization image for STPG1 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for STPG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with STPG1: view

Pathways & Interactions for STPG1 Gene

SuperPathways for STPG1 Gene

No Data Available

Interacting Proteins for STPG1 Gene

Gene Ontology (GO) - Biological Process for STPG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006915 apoptotic process IEA --
genes like me logo Genes that share ontologies with STPG1: view

No data available for Pathways by source and SIGNOR curated interactions for STPG1 Gene

Drugs & Compounds for STPG1 Gene

No Compound Related Data Available

Transcripts for STPG1 Gene

Unigene Clusters for STPG1 Gene

Sperm-tail PG-rich repeat containing 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for STPG1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for STPG1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12a · 12b
SP1: - -
SP2: - - - -
SP3: -
SP4: -
SP5:

Relevant External Links for STPG1 Gene

GeneLoc Exon Structure for
STPG1
ECgene alternative splicing isoforms for
STPG1

Expression for STPG1 Gene

mRNA expression in normal human tissues for STPG1 Gene

mRNA differential expression in normal tissues according to GTEx for STPG1 Gene

This gene is overexpressed in Testis (x5.1).

Protein differential expression in normal tissues from HIPED for STPG1 Gene

This gene is overexpressed in Bone (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for STPG1 Gene



SOURCE GeneReport for Unigene cluster for STPG1 Gene Hs.403187

genes like me logo Genes that share expression patterns with STPG1: view

Protein tissue co-expression partners for STPG1 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for STPG1 Gene

Orthologs for STPG1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for STPG1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia STPG1 35
  • 83.83 (n)
  • 81.14 (a)
STPG1 36
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia STPG1 35
  • 84.33 (n)
  • 79.94 (a)
STPG1 36
  • 79 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Stpg1 35
  • 75.48 (n)
  • 71.77 (a)
Stpg1 16
Stpg1 36
  • 69 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia STPG1 35
  • 99.3 (n)
  • 99.4 (a)
STPG1 36
  • 95 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Stpg1 35
  • 76.22 (n)
  • 72.56 (a)
oppossum
(Monodelphis domestica)
Mammalia STPG1 36
  • 58 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia STPG1 36
  • 54 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia STPG1 36
  • 43 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia stpg1 35
  • 56.88 (n)
  • 51.82 (a)
zebrafish
(Danio rerio)
Actinopterygii stpg1 35
  • 50.69 (n)
  • 40.58 (a)
stpg1 36
  • 39 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 35 (a)
OneToOne
Species with no ortholog for STPG1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for STPG1 Gene

ENSEMBL:
Gene Tree for STPG1 (if available)
TreeFam:
Gene Tree for STPG1 (if available)

Paralogs for STPG1 Gene

No data available for Paralogs for STPG1 Gene

Variants for STPG1 Gene

Sequence variations from dbSNP and Humsavar for STPG1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs118094175 -- 24,367,865(+) CCCTA(C/G/T)GAGAT intron-variant
rs117805097 -- 24,383,975(+) TAACA(C/T)TGTAG reference, missense, utr-variant-5-prime
rs117605412 -- 24,408,608(+) TGTAG(A/G/T)ACTCA intron-variant
rs117468711 -- 24,376,430(+) TGAGC(A/G)TGTAT intron-variant
rs117441784 -- 24,402,377(+) TTTAT(A/G)GTGGT intron-variant

Variation tolerance for STPG1 Gene

Residual Variation Intolerance Score: 87.39% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.25; 88.11% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for STPG1 Gene

HapMap Linkage Disequilibrium report
STPG1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for STPG1 Gene

Disorders for STPG1 Gene

Relevant External Links for STPG1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
STPG1
genes like me logo Genes that share disorders with STPG1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for STPG1 Gene

Publications for STPG1 Gene

  1. The identification of a novel gene, MAPO2, that is involved in the induction of apoptosis triggered by O(6)-methylguanine. (PMID: 23028632) Fujikane R. … Hidaka M. (PLoS ONE 2012) 2 67
  2. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PMID: 19690332) Mayya V. … Han D.K. (Sci. Signal. 2009) 67
  3. The consensus coding sequences of human breast and colorectal cancers. (PMID: 16959974) Sjoeblom T. … Velculescu V.E. (Science 2006) 67
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for STPG1 Gene

Sources for STPG1 Gene

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