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Aliases for STOX2 Gene

Aliases for STOX2 Gene

  • Storkhead Box 2 2 3
  • KIAA1392 4

External Ids for STOX2 Gene

Summaries for STOX2 Gene

GeneCards Summary for STOX2 Gene

STOX2 (Storkhead Box 2) is a Protein Coding gene. An important paralog of this gene is STOX1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STOX2 Gene

Genomics for STOX2 Gene

Genomic Location for STOX2 Gene

Start:
183,853,431 bp from pter
End:
184,023,526 bp from pter
Size:
170,096 bases
Orientation:
Plus strand

Genomic View for STOX2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for STOX2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STOX2 Gene

Regulatory Elements for STOX2 Gene

Proteins for STOX2 Gene

  • Protein details for STOX2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P2F5-STOX2_HUMAN
    Recommended name:
    Storkhead-box protein 2
    Protein Accession:
    Q9P2F5
    Secondary Accessions:
    • A6H8U4
    • Q9NPS8

    Protein attributes for STOX2 Gene

    Size:
    926 amino acids
    Molecular mass:
    102671 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA92630.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for STOX2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for STOX2 Gene

Proteomics data for STOX2 Gene at MOPED

Post-translational modifications for STOX2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for STOX2 Gene

No data available for DME Specific Peptides for STOX2 Gene

Domains for STOX2 Gene

Protein Domains for STOX2 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with STOX2: view

No data available for Gene Families and UniProtKB/Swiss-Prot for STOX2 Gene

Function for STOX2 Gene

Gene Ontology (GO) - Molecular Function for STOX2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with STOX2: view

miRNA for STOX2 Gene

miRTarBase miRNAs that target STOX2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for STOX2 Gene

Localization for STOX2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for STOX2 Gene COMPARTMENTS Subcellular localization image for STOX2 gene
Compartment Confidence
nucleus 3
cytosol 1

Gene Ontology (GO) - Cellular Components for STOX2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with STOX2: view

Pathways for STOX2 Gene

SuperPathways for STOX2 Gene

No Data Available

Interacting Proteins for STOX2 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000311257%0d%0a9606.ENSP00000352929%0d%0a
Selected Interacting proteins: ENSP00000311257 for STOX2 Gene via STRING

Symbol External ID(s) Details
CSNK1E

Gene Ontology (GO) - Biological Process for STOX2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001893 maternal placenta development IEP 20643876
GO:0009790 embryo development IEP 20643876
genes like me logo Genes that share ontologies with STOX2: view

No data available for Pathways by source for STOX2 Gene

Transcripts for STOX2 Gene

Unigene Clusters for STOX2 Gene

Storkhead box 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for STOX2 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b
SP1: -
SP2:
SP3: - -

Relevant External Links for STOX2 Gene

GeneLoc Exon Structure for
STOX2
ECgene alternative splicing isoforms for
STOX2

Expression for STOX2 Gene

mRNA expression in normal human tissues for STOX2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for STOX2 Gene

SOURCE GeneReport for Unigene cluster for STOX2 Gene Hs.21958

genes like me logo Genes that share expressions with STOX2: view

Orthologs for STOX2 Gene

This gene was present in the common ancestor of animals.

Orthologs for STOX2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia STOX2 36
  • 99.71 (n)
  • 100 (a)
STOX2 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia STOX2 36
  • 89.27 (n)
  • 94.49 (a)
STOX2 37
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia STOX2 36
  • 91.32 (n)
  • 95.9 (a)
STOX2 37
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Stox2 36
  • 88.41 (n)
  • 95.57 (a)
Stox2 16
Stox2 37
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia STOX2 37
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia STOX2 37
  • 89 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Stox2 36
  • 89.09 (n)
  • 95.14 (a)
chicken
(Gallus gallus)
Aves STOX2 36
  • 78.74 (n)
  • 87.59 (a)
STOX2 37
  • 78 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia STOX2 37
  • 72 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.34676 36
tropical clawed frog
(Silurana tropicalis)
Amphibia stox2 36
  • 74.44 (n)
  • 79.56 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.16351 36
STOX2 (2 of 2) 37
  • 61 (a)
OneToMany
stox2a 36
  • 64.8 (n)
  • 68.8 (a)
stox2a 37
  • 55 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta ko 37
  • 11 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea ham-1 37
  • 18 (a)
OneToMany
Species with no ortholog for STOX2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for STOX2 Gene

ENSEMBL:
Gene Tree for STOX2 (if available)
TreeFam:
Gene Tree for STOX2 (if available)

Paralogs for STOX2 Gene

Paralogs for STOX2 Gene

genes like me logo Genes that share paralogs with STOX2: view

Variants for STOX2 Gene

Sequence variations from dbSNP and Humsavar for STOX2 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs892835 -- 183,928,303(-) GACCA(C/T)GGGGG intron-variant
rs1009182 -- 183,923,998(-) gctaa(C/G)atgtg intron-variant
rs1133359 -- 184,022,347(+) AGCCC(A/G)CAAGG utr-variant-3-prime
rs1435436 -- 183,935,171(-) ATCCA(C/T)GCTGG intron-variant
rs1435437 -- 183,935,030(-) TTTGC(C/T)TTGTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for STOX2 Gene

Variant ID Type Subtype PubMed ID
nsv881675 CNV Gain 21882294
nsv822878 CNV Gain 20364138
nsv830166 CNV Gain 17160897
esv2608282 CNV Deletion 19546169
esv2728882 CNV Deletion 23290073
esv1964372 CNV Deletion 18987734
esv4197 CNV Deletion 18987735
esv2728883 CNV Deletion 23290073
esv2728885 CNV Deletion 23290073
esv2728886 CNV Deletion 23290073
nsv4637 CNV Insertion 18451855

Relevant External Links for STOX2 Gene

HapMap Linkage Disequilibrium report
STOX2

Disorders for STOX2 Gene

Relevant External Links for STOX2

Genetic Association Database (GAD)
STOX2
Human Genome Epidemiology (HuGE) Navigator
STOX2
genes like me logo Genes that share disorders with STOX2: view

No data available for UniProtKB/Swiss-Prot for STOX2 Gene

Publications for STOX2 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  4. STOX2 but not STOX1 is differentially expressed in decidua from pre-eclamptic women: data from the Second Nord-Trondelag Health Study. (PMID: 20643876) Fenstad M.H. … Austgulen R. (Mol. Hum. Reprod. 2010) 3
  5. Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. (PMID: 23400010) Del-Aguila J.L. … Boerwinkle E. (Pharmacogenomics J. 2013) 3

Products for STOX2 Gene

Sources for STOX2 Gene

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