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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STOX1 Gene

protein-coding   GIFtS: 50
GCID: GC10P070587

Storkhead Box 1

(Previous name: chromosome 10 open reading frame 24)
(Previous symbol: C10orf24)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Storkhead Box 11 2
C10orf241 2 3
Winged-Helix Domain-Containing Protein2 3
PEE42 5
Chromosome 10 Open Reading Frame 241
Storkhead-Box Protein 12

External Ids:    HGNC: 235081   Entrez Gene: 2197362   Ensembl: ENSG000001657307   OMIM: 6093975   UniProtKB: Q6ZVD73   

Export aliases for STOX1 gene to outside databases

Previous GC identifers: GC10P070258 GC10P064588


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for STOX1 Gene:
The protein encoded by this gene may function as a DNA binding protein. Mutations in this gene are associated with
pre-eclampsia/eclampsia 4 (PEE4). Alternatively spliced transcript variants encoding different isoforms have been
found for this gene. (provided by RefSeq, Sep 2009)

GeneCards Summary for STOX1 Gene: 
STOX1 (storkhead box 1) is a protein-coding gene. Diseases associated with STOX1 include eclampsia, and pre-eclampsia/eclampsia 4. GO annotations related to this gene include DNA binding. An important paralog of this gene is STOX2.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STOX1 gene promoter:
         Elk-1   Spz1   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for STOX1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STOX1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.1   Ensembl cytogenetic band:  10q21.3   HGNC cytogenetic band: 10q22.1

STOX1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STOX1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P070587:  view genomic region     (about GC identifiers)

Start:
70,587,294 bp from pter      End:
70,655,209 bp from pter
Size:
67,916 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: STOX1_HUMAN, Q6ZVD7 (See protein sequence)
Recommended Name: Storkhead-box protein 1  
Size: 989 amino acids; 110962 Da
Subunit: Binds DNA (By similarity)
Subcellular location: Isoform A: Cytoplasm. Nucleus. Note=Either found in the cytoplasm or in the nucleus. Nuclear
expression of isoform A seems to be restricted to polyploid trophoblast cells
Subcellular location: Isoform B: Nucleus
Subcellular location: Isoform C: Nucleus, nucleolus
Sequence caution: Sequence=AAH63627.1; Type=Erroneous initiation; Sequence=BAB71600.1; Type=Erroneous initiation;
Sequence=BAB71607.1; Type=Erroneous initiation; Sequence=BAC85925.1; Type=Erroneous initiation;
Sequence=BAC87173.1; Type=Erroneous initiation;
Secondary accessions: A2A3Q9 A5D6Y7 B0QZA4 B0QZA5 B0QZA6 Q4F8Q6 Q5I946 Q5I947 Q5I948 Q5VX38
Q5VX39 Q6ZRY3 Q96LR3 Q96LS0
Alternative splicing: 3 isoforms:  Q6ZVD7-1   Q6ZVD7-2   Q6ZVD7-3   

Explore the universe of human proteins at neXtProt for STOX1: NX_Q6ZVD7

Explore proteomics data for STOX1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6ZVD7

  • STOX1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    STOX1 Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001123631.1  NP_001123632.1  NP_001123633.1  NP_001123634.1  NP_689922.3  

    ENSEMBL proteins: 
     ENSP00000298596   ENSP00000382121   ENSP00000382118   ENSP00000382115   ENSP00000394509  

    Human Recombinant Protein Products for STOX1: 
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for STOX1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--

    STOX1 for ontologies           About GeneDecksing



    STOX1 Antibody Products: 
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    Novus Biologicals STOX1 Antibody
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    Cloud-Clone Corp. Antibodies for STOX1 
    ThermoFisher Antibodies for STOX1
    LSBio Antibodies in human, mouse, rat for STOX1 

    Assay Products for STOX1: 
    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for STOX1 
    Cloud-Clone Corp. CLIAs for STOX1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR019391 Storkhead-box_winged-helix

    Graphical View of Domain Structure for InterPro Entry Q6ZVD7

    ProtoNet protein and cluster: Q6ZVD7


    STOX1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
         
    STOX1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for STOX1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for STOX1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for STOX1 
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    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate STOX1:
    hsa-miR-150
    SwitchGear 3'UTR luciferase reporter plasmidSTOX1 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STOX1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for STOX1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for STOX1 (ENSP000002985964) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GCLMENSP000003592584STRING: ENSP00000359258
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STOX1

    Search CenterWatch for drugs/clinical trials and news about STOX1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for STOX1 gene (5 alternative transcripts): 
    NM_001130159.2  NM_001130160.2  NM_001130161.2  NM_001130162.2  NM_152709.4  

    Unigene Cluster for STOX1:

    Storkhead box 1
    Hs.37636  [show with all ESTs]
    Unigene Representative Sequence: NM_152709
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000298596(uc001joq.3 uc001jor.3 uc009xpy.3 uc021prw.1)
    ENST00000399169(uc001jos.2) ENST00000399165 ENST00000399162 ENST00000421961


    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat STOX1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate STOX1:
    hsa-miR-150
    SwitchGear 3'UTR luciferase reporter plasmidSTOX1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for STOX1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat STOX1
    Clone
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    OriGene clones in human, mouse for STOX1 (see all 23)
    OriGene ORF clones in mouse, rat for STOX1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): STOX1 (NM_152709)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for STOX1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STOX1
    Sirion Biotech Customized lentivirus for stable overexpression of STOX1 
                         Customized lentivirus expression plasmids for stable overexpression of STOX1 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for STOX1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat STOX1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat STOX1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STOX1

    Additional mRNA sequence: 

    AK057891.1 AK124681.1 AK127878.1 AY842014.1 AY842015.1 AY842016.1 AY842017.1 BC063627.1 
    BC140011.1 

    5 DOTS entries:

    DT.97824045  DT.40111832  DT.212012  DT.100735659  DT.212013 

    24/31 AceView cDNA sequences (see all 31):

    AA704430 AK057891 AK057864 AA453046 BC063627 N34830 AK127878 AW130781 
    BX110231 CB241839 AK124681 AA442072 CK429168 AW340422 BM450800 BG677965 
    AA699315 AA682477 BE904845 BQ045446 AW086180 AA470379 AA452877 H58963 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for STOX1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6
    SP1:                                      -         
    SP2:                          -                     
    SP3:                                                
    SP4:        -                                       
    SP5:                    -     -                     


    ECgene alternative splicing isoforms for STOX1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STOX1 expression in normal human tissues (normalized intensities)      STOX1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAGAATTGA
    STOX1 Expression
    About this image


    STOX1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Epithelium (Respiratory System)    fully expand to see all 2 entries
             bronchial epithelial cells   
     
     Pancreas (Endocrine System)
             Posterior foregut-like cells ( A scalable, suspension protocol for derivation of...
     
     Neural Tube (Nervous System)
             Mesencephalic Floor Plate
     
     Brain (Nervous System)
             N2/LSB/S/F8/CHIR-induced cells ( Generation of midbrain dopaminergic, forebrain and...

    See STOX1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STOX1

    SOURCE GeneReport for Unigene cluster: Hs.37636
        SABiosciences Custom PCR Arrays for STOX1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STOX1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for STOX1 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Stox11 , 5 storkhead box 11, 5 71.09(n)1
    61.12(a)1
      10 (32.45 cM)5
    2160211  NM_001033260.11  NP_001028432.11 
     626590435 
    chicken
    (Gallus gallus)
    Aves LOC1008580741 storkhead-box protein 1-like 52(n)
    37.52(a)
      100858074  XM_003641470.1  XP_003641518.1 
    lizard
    (Anolis carolinensis)
    Reptilia STOX16
    Uncharacterized protein
    40(a)
    1 ↔ 1
    GL343215.1(1829839-1868401)
    zebrafish
    (Danio rerio)
    Actinopterygii CB891025.12   -- 78.71(n)   378731  CB891025.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta ko6
    knockout
    11(a)
    1 → many
    3L(21068681-21124259)
    worm
    (Caenorhabditis elegans)
    Secernentea ham-16
    Protein HAM-1
    15(a)
    1 → many
    IV(12542034-12545724)


    ENSEMBL Gene Tree for STOX1 (if available)
    TreeFam Gene Tree for STOX1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for STOX1 gene
    STOX22  

    STOX1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1581 SNPs in STOX1 are shown (see all 1581)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0237844
    Pre-eclampsia/eclampsia 4 (PEE4)4--see VAR_0237842 R P mis40--------
    rs13416671,2,4
    C,F,O,A,HPre-eclampsia/eclampsia 4 (PEE4)4 other171015682(-) TGGGTG/AATGTT 10 /H /Y mis1 tfbs338Minor allele frequency- A:0.35NA EA NS WA EU 6383
    rs412785321,2,4
    C,FPre-eclampsia/eclampsia 4 (PEE4)4 --71019846(+) CCTAAA/TTTCAG 8 N I mis1 int12Minor allele frequency- T:0.01NA EU 1325
    rs105093051,2,4
    C,F,Hpathogenic171019196(+) TATGAA/CGTGTA 8 E D mis1 int1109Minor allele frequency- N:0.00NS EA NA PA EU CA WA CSA 8260
    rs15738391,2
    C,F--64588439(-) GCTCTT/CCGCAG 5 -- us2k18Minor allele frequency- C:0.35MN WA NA CSA EA 550
    rs16189321,2
    C,F,A--64588440(-) GGCTCC/TCCGCA 5 -- us2k14Minor allele frequency- T:0.02MN WA NA CSA 189
    rs612306521,2
    C--64600337(+) CTTTG-/AGAAAG 5 -- int11Minor allele frequency- A:0.50CSA 2
    rs113327001,2
    C--64603576(+) AGAGAT/-GGAAT 5 -- int11Minor allele frequency- -:0.50CSA 2
    rs24901661,2
    C--64610234(+) TTTTTA/TAAAAA 5 -- int13Minor allele frequency- T:0.22WA NA 240
    rs2003556951,2
    --64633743(+) TCTTT-/CTTTTT 5 -- int10--------

    HapMap Linkage Disequilibrium report for STOX1 (70587294 - 70655209 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/15 variations for STOX1 (see all 15):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2590445CNV Deletion19546169
    dgv151e199CNV Deletion23128226
    esv2738073CNV Deletion23290073
    esv1719721CNV Deletion17803354
    esv1165433CNV Deletion17803354
    esv2738062CNV Deletion23290073
    nsv516725CNV Loss19592680
    nsv437688CNV Loss16327808
    nsv8685CNV Loss18304495
    esv25403CNV Loss19812545


    Human Gene Mutation Database (HGMD): STOX1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing STOX1
    DNA2.0 Custom Variant and Variant Library Synthesis for STOX1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609397    OMIM disorders: --

    UniProtKB/Swiss-Prot: STOX1_HUMAN, Q6ZVD7
  • Pre-eclampsia/eclampsia 4 (PEE4) [MIM:609404]: A hypertensive disorder of pregnancy characterized by new
    hypertension (blood pressure 140/90 or greater) presenting after 20 weeks' gestation with clinically relevant
    proteinuria. It impacts 2 individuals, the mother and her child, both of whom can be severely affected.
    Preeclampsia is one of the causes of maternal mortality and morbidity worldwide. Note=The disease is caused by
    mutations affecting the gene represented in this entry

  • 6 diseases for STOX1:    About MalaCards
    eclampsia    pre-eclampsia/eclampsia 4    pre-eclampsia    choriocarcinoma
    alzheimer's disease    hypertension

    1 disease from the University of Copenhagen DISEASES database for STOX1:
    pre-eclampsia

    STOX1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): STOX1
    Human Genome Epidemiology (HuGE) Navigator: STOX1 (2 documents)

    Export disorders for STOX1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STOX1 gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with STOX1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Maternal segregation of the Dutch preeclampsia locus at 10q22 with a new member of the winged helix gene family. (PubMed id 15806103)1, 2, 9 van Dijk M.... Oudejans C.B.M. (2005)
    2. Evaluation of STOX1 as a preeclampsia candidate gene in a population-wide sample. (PubMed id 17290274)1, 4 Kivinen K....Kere J. (2007)
    3. STOX1 gene in pre-eclampsia and intrauterine growth restriction. (PubMed id 17617193)1, 4 Berends A.L....Steegers E.A. (2007)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    7. Novel genetic variants associated with lumbar disc deg eneration in northern Europeans: a meta-analysis of 4600 subjects. (PubMed id 22993228)1 Williams F.M....Spector T.D. (2013)
    8. Transcription factor STOX1A promotes mitotic entry by binding to the CCNB1 promotor. (PubMed id 22253775)1 Abel D.v....Oudejans C.B. (2012)
    9. Direct downregulation of CNTNAP2 by STOX1A is associat ed with Alzheimer's disease. (PubMed id 22728895)1 van Abel D....Oudejans C.B. (2012)
    10. STOX1A induces phosphorylation of tau proteins at epit opes hyperphosphorylated in Alzheimer's disease. (PubMed id 22995177)1 van Abel D....Oudejans C.B. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 219736 HGNC: 23508 AceView: C10orf24 Ensembl:ENSG00000165730 euGenes: HUgn219736
    ECgene: STOX1 H-InvDB: STOX1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for STOX1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for STOX1 gene:
    Search GeneIP for patents involving STOX1

    GeneCards and IP:
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