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GIFtS

STOX1 Gene

protein-coding   GIFtS: 48
GCID: GC10P070587

storkhead box 1

(Previous name: chromosome 10 open reading frame 24 )
(Previous symbol: C10orf24)
 Explore 6 diseases affiliated with
STOX1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for STOX1    

Aliases
for STOX1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Storkhead Box 11 2     FLJ251621
C10orf241 2 3     Chromosome 10 Open Reading Frame 241
Winged-Helix Domain-Containing Protein2 3     Storkhead-Box Protein 12
PEE42 5     

External Ids:    HGNC: 235081   Entrez Gene: 2197362   Ensembl: ENSG000001657307   OMIM: 6093975   UniProtKB: Q6ZVD73   

Export aliases for STOX1 gene to outside databases

Previous GC identifers: GC10P070258 GC10P064588


Summaries
for STOX1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for STOX1:
The protein encoded by this gene may function as a DNA binding protein. Mutations in this gene are associated with
pre-eclampsia/eclampsia 4 (PEE4). Alternatively spliced transcript variants encoding different isoforms have been
found for this gene. (provided by RefSeq, Sep 2009)




Genomic Views
for STOX1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STOX1 gene promoter:
         Elk-1   Spz1   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for STOX1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STOX1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.1   Ensembl cytogenetic band:  10q21.3   HGNC cytogenetic band: 10q22.1

STOX1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STOX1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P070587:  view genomic region     (about GC identifiers)

Start:
 70,587,294 bp from pter      End:
 70,655,209 bp from pter
Size:
 67,916 bases      Orientation:
 plus strand

Proteins
for STOX1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: STOX1_HUMAN, Q6ZVD7 (See protein sequence)
Recommended Name: Storkhead-box protein 1  
Size: 989 amino acids; 110962 Da
Subunit: Binds DNA (By similarity)
Subcellular location: Isoform A: Cytoplasm. Nucleus. Note=Either found in the cytoplasm or in the nucleus. Nuclear
expression of isoform A seems to be restricted to polyploid trophoblast cells
Subcellular location: Isoform B: Nucleus
Subcellular location: Isoform C: Nucleus, nucleolus
Sequence caution: Sequence=AAH63627.1; Type=Erroneous initiation; Sequence=BAB71600.1; Type=Erroneous initiation;
Sequence=BAB71607.1; Type=Erroneous initiation; Sequence=BAC85925.1; Type=Erroneous initiation; Sequence=BAC87173.1;
Type=Erroneous initiation;
Secondary accessions: A2A3Q9 A5D6Y7 B0QZA4 B0QZA5 B0QZA6 Q4F8Q6 Q5I946 Q5I947 Q5I948 Q5VX38 Q5VX39
Q6ZRY3 Q96LR3 Q96LS0
Alternative splicing: 3 isoforms:  Q6ZVD7-1   Q6ZVD7-2   Q6ZVD7-3   

Explore the universe of human proteins at neXtProt for STOX1: NX_Q6ZVD7

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6ZVD7

    • STOX1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (5 alternative transcripts): 
    NP_001123631.1  NP_001123632.1  NP_001123633.1  NP_001123634.1  NP_689922.3  

    ENSEMBL proteins: 
     ENSP00000382121   ENSP00000298596   ENSP00000382118   ENSP00000382115   ENSP00000394509  

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    OriGene Protein Over-expression Lysate: STOX1
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for STOX1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--


    STOX1 for ontologies           About GeneDecksing



    STOX1 Antibody Products: 
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    Uscn Antibodies for STOX1
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    Uscn ELISAs and CLIAs for STOX1

    Protein Domains /
    Families
    for STOX1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    STOX1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR019391 Storkhead-box_winged-helix

    Graphical View of Domain Structure for InterPro Entry Q6ZVD7

    ProtoNet protein and cluster: Q6ZVD7


    Function
    for STOX1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    miRNA
    Products:            		 OriGene 3'-UTR Clone (see all 5): STOX1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat STOX1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate STOX1:
    hsa-miR-150
    SwitchGear 3'UTR luciferase reporter plasmid: STOX1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STOX1 (see all 4)
    OriGene shRNA RFP: STOX1
    OriGene siRNA: STOX1
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    Gene Editing
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for STOX1 (see all 6)
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    Cell Line
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    Search LifeMap BioReagents cell lines for STOX1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STOX1

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--


    STOX1 for ontologies           About GeneDecksing



    Pathways & Interactions
    for STOX1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for STOX1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for STOX1 (ENSP000002985964) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GCLMENSP000003592584STRING: ENSP00000359258
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Drugs & Compounds
    for STOX1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STOX1
    Search CenterWatch for drugs/clinical trials and news about STOX1 

    Transcripts
    for STOX1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for STOX1 gene (5 alternative transcripts): 
    NM_001130159.2  NM_001130160.2  NM_001130161.2  NM_001130162.2  NM_152709.4  

    Unigene Cluster for STOX1:

    Storkhead box 1
    Hs.37636  [show with all ESTs]
    Unigene Representative Sequence: NM_152709
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000399169(uc001jos.2) ENST00000298596(uc001joq.3 uc001jor.3 uc009xpy.3 uc021prw.1)
    ENST00000399165 ENST00000399162 ENST00000421961

    miRNA
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    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat STOX1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate STOX1:
    hsa-miR-150
    SwitchGear 3'UTR luciferase reporter plasmid: STOX1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STOX1 (see all 4)
    OriGene shRNA RFP: STOX1
    OriGene siRNA: STOX1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat STOX1
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for STOX1 (see all 5)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 5): STOX1 (NM_152709)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for STOX1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STOX1 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat STOX1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STOX1

    Additional cDNA sequence: 

    AK057891.1 AK124681.1 AK127878.1 AY842014.1 AY842015.1 AY842016.1 AY842017.1 BC063627.1 
    BC140011.1 

    5 DOTS entries:

    DT.97824045  DT.40111832  DT.212012  DT.100735659  DT.212013 

    24/31 AceView cDNA sequences (see all 31):

    N34830 AA704430 AA453046 AK057864 BC063627 BX110231 CB241839 AK057891 
    AK127878 AW130781 AW086180 BG677965 BM450800 AK124681 CK429168 AW340422 
    AA442072 BE904845 BQ045446 AA682477 AA699315 H58917 AA452877 AA470379 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for STOX1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6
    SP1:                                      -         
    SP2:                          -                     
    SP3:                                                
    SP4:        -                                       
    SP5:                    -     -                     


    ECgene alternative splicing isoforms for STOX1

    Expression
    for STOX1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STOX1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TAAGAATTGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    STOX1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyS-shaped BodyKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    N2/LSB/S/F8/CHIR-induced cells (Generation of midbra...)
    Posterior foregut-like cells (A scalable, suspensi...)

    See STOX1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STOX1

    SOURCE GeneReport for Unigene cluster: Hs.37636
        SABiosciences Custom PCR Arrays for STOX1
    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STOX1

    Orthologs
    for STOX1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for STOX1 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Stox11 , 5 storkhead box 11, 5 71.09(n)1
    61.12(a)1    		   10 (32.45 cM)5
    2160211  NM_001033260.11  NP_001028432.11 
     626590435 
    chicken
    (Gallus gallus)    		 Aves LOC1008580741 storkhead-box protein 1-like 52(n)
    37.52(a)    		   100858074  XM_003641470.1  XP_003641518.1 
    lizard
    (Anolis carolinensis)    		 Reptilia STOX16
    		 --
    		 41(a)
    		 1 ↔ 1
    		 GL343215.1(1829974-1866051)
    zebrafish
    (Danio rerio)    		 Actinopterygii CB891025.12   -- 78.71(n)   378731  CB891025.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta ko6
    		 knockout
    		 13(a)
    		 1 → many
    		 3L(21068681-21124259)
    worm
    (Caenorhabditis elegans)    		 Secernentea ham-16
    		 HSN Abnormal Migration family member (ham-1)
    		 20(a)
    		 1 → many
    		 IV(12542011-12545701)


    ENSEMBL Gene Tree for STOX1 (if available)
    TreeFam Gene Tree for STOX1 (if available) 

    Paralogs
    for STOX1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for STOX1 gene
    STOX22  

    STOX1 for paralogs           About GeneDecksing



    Genomic Variants
    for STOX1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1308 NCBI SNPs in STOX1 are shown (see all 1308)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 10 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs105093051,2
    		C,F,H,pathogenic64646877(+) TATGAA/CGTGTA 8 E D mis1 int1109Minor allele frequency- N:0.00NS EA NA PA EU CA WA CSA 8260
    rs774079721,2
    		--64587441(+) GGTCAC/TATTCT 5 -- us2k11Minor allele frequency- T:0.01WA 118
    rs741432381,2
    		C,--64587498(+) TGTCCG/CTCTTT 5 -- us2k11Minor allele frequency- C:0.50WA 2
    rs15738391,2
    		C,F,--64588439(-) GCTCTT/CCGCAG 5 -- us2k18Minor allele frequency- C:0.35MN WA NA CSA EA 550
    rs772966301,2
    		--64588440(+) TGCGAA/GGAGCC 5 -- us2k12Minor allele frequency- G:0.33NA CSA 3
    rs714788601,2
    		C,--64588611(+) CCGGCC/GTAAGC 5 -- us2k12Minor allele frequency- G:0.18NA 122
    rs122411231,2
    		F,--64589191(+) GGCCCC/TGTCTT 5 -- int11Minor allele frequency- T:0.04WA 118
    rs169258201,2
    		C,F,H,--64589532(+) CTTTAT/CTATTA 5 -- int110Minor allele frequency- C:0.07NA NS EA CSA WA 669
    rs758742101,2
    		C,--64590217(+) GGGGCG/ATGGTG 5 -- int12Minor allele frequency- A:0.03WA 120
    rs756912691,2
    		--64590566(+) GCCCCC/TGTTTT 5 -- int10--------

    HapMap Linkage Disequilibrium report for STOX1 (70587294 - 70655209 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 13 variations for STOX1
         11 CNVs: 71035 1230 85356 31753 85357 10334 3808 38207 48613 65714 100973
         2 Indels: 24546 24545
    Human Gene Mutation Database (HGMD): STOX1

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing STOX1
    DNA2.0 Custom Variant and Variant Library Synthesis for STOX1

    Disorders / Diseases
    for STOX1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    STOX1 for disorders           About GeneDecksing

    OMIM gene information: 609397    OMIM disorders: --

    UniProtKB/Swiss-Prot: STOX1_HUMAN, Q6ZVD7
  • Defects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4) [MIM:609404]; also known as gestational
    • proteinuric hypertension. Preeclampsia is a pregnancy-associated disease with maternal symptoms but placental origin.
    Unlike most other human disorders, it impacts 2 individuals, the mother and her child, both of whom can be severely
    affected. The pathological mechanism of PEE4 involves the loss of function of STOX1 in the placenta

    6 diseases for STOX1:    About MalaCards
    pre-eclampsia    eclampsia    preeclampsia/eclampsia 4    choriocarcinoma
    alzheimer's disease    neuronitis

    1 disease from the University of Copenhagen DISEASES database for STOX1:
    pre-eclampsia
    Human Genome Epidemiology (HuGE) Navigator: STOX1 (2 documents)

    Export disorders for STOX1 gene to outside databases

    Publications
    for STOX1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STOX1 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with STOX1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Maternal segregation of the Dutch preeclampsia locus at 10q22 with a new member of the winged helix gene family. (PubMed id 15806103)1, 2, 9 van Dijk M.... Oudejans C.B.M. (2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    5. Transcription factor STOX1A promotes mitotic entry by binding to the CCNB1 promotor. (PubMed id 22253775)1 Abel D.v....Oudejans C.B. (2012)
    6. STOX1A induces phosphorylation of tau proteins at epit opes hyperphosphorylated in Alzheimer's disease. (PubMed id 22995177)1 van Abel D....Oudejans C.B. (2012)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    9. SFRS7-mediated splicing of tau exon 10 is directly re gulated by STOX1A in glial cells. (PubMed id 21755018)1 van Abel D....Oudejans C.B. (2011)
    10. STOX2 but not STOX1 is differentially expressed in de cidua from pre-eclamptic women: data from the Second Nord-Trondelag Health Stud y. (PubMed id 20643876)1 Fenstad M.H....Austgulen R. (2010)

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    Genome Databases showing STOX1 gene

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    Entrez Gene: 219736 HGNC: 23508 AceView: C10orf24 Ensembl:ENSG00000165730 euGenes: HUgn219736
    ECgene: STOX1 H-InvDB: STOX1

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    Specialized Databases showing STOX1 gene

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