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Aliases for STMND1 Gene

Aliases for STMND1 Gene

  • Stathmin Domain Containing 1 2 3 5

External Ids for STMND1 Gene

Summaries for STMND1 Gene

GeneCards Summary for STMND1 Gene

STMND1 (Stathmin Domain Containing 1) is a Protein Coding gene. GO annotations related to this gene include tubulin binding.

Additional gene information for STMND1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STMND1 Gene

Genomics for STMND1 Gene

Regulatory Elements for STMND1 Gene

Enhancers for STMND1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06H017012 1.4 FANTOM5 Ensembl ENCODE 8.3 -87.9 -87925 4 CTCF ZNF211 JUN BATF CTBP1 GATA3 POLR2A NFYB FOS RUNX3 STMND1 LOC105374951 GC06P016983
GH06H017276 1.7 FANTOM5 Ensembl ENCODE dbSUPER 5.3 +178.0 178045 7 ZFP64 SIN3A RAD21 GLIS2 SCRT2 FOS CEBPB MAFF ZNF341 KDM1A CAP2 RBM24 STMND1 LOC101928463
GH06H016945 1.3 Ensembl ENCODE 5.5 -154.2 -154215 4 ATF1 FEZF1 BRCA1 ZNF2 YY1 GATA2 ATF7 SP3 TSHZ1 REST STMND1 GC06P016983 GC06P016871
GH06H017287 1.2 Ensembl ENCODE dbSUPER 4.4 +187.9 187863 5 SOX6 TAL1 MAFG REST ATF2 RFX5 ZNF316 MAFF SCRT2 MAFK CAP2 STMND1 RBM24 GC06P017304
GH06H017095 0.5 ENCODE 8.6 -6.0 -6009 0 ZFP64 KDM1A ZBTB20 TEAD3 STMND1 PIR44691
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around STMND1 on UCSC Golden Path with GeneCards custom track

Genomic Location for STMND1 Gene

Chromosome:
6
Start:
17,102,258 bp from pter
End:
17,131,372 bp from pter
Size:
29,115 bases
Orientation:
Plus strand

Genomic View for STMND1 Gene

Genes around STMND1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
STMND1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for STMND1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STMND1 Gene

Proteins for STMND1 Gene

  • Protein details for STMND1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H3BQB6-STMD1_HUMAN
    Recommended name:
    Stathmin domain-containing protein 1
    Protein Accession:
    H3BQB6

    Protein attributes for STMND1 Gene

    Size:
    276 amino acids
    Molecular mass:
    30984 Da
    Quaternary structure:
    No Data Available

neXtProt entry for STMND1 Gene

Post-translational modifications for STMND1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for STMND1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for STMND1 Gene

Domains & Families for STMND1 Gene

Gene Families for STMND1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted secreted proteins

Protein Domains for STMND1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with STMND1: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for STMND1 Gene

Function for STMND1 Gene

Phenotypes From GWAS Catalog for STMND1 Gene

Phenotypes for STMND1 Gene

GenomeRNAi human phenotypes for STMND1:
genes like me logo Genes that share phenotypes with STMND1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for STMND1 Gene

Localization for STMND1 Gene

Subcellular locations from the

Human Protein Atlas (HPA)
  • Actin filaments (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for STMND1 Gene

Pathways & Interactions for STMND1 Gene

SuperPathways for STMND1 Gene

No Data Available

Interacting Proteins for STMND1 Gene

Gene Ontology (GO) - Biological Process for STMND1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0031110 regulation of microtubule polymerization or depolymerization IEA --
genes like me logo Genes that share ontologies with STMND1: view

No data available for Pathways by source and SIGNOR curated interactions for STMND1 Gene

Drugs & Compounds for STMND1 Gene

No Compound Related Data Available

Transcripts for STMND1 Gene

mRNA/cDNA for STMND1 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for STMND1 Gene

Stathmin domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for STMND1 Gene

No ASD Table

Relevant External Links for STMND1 Gene

GeneLoc Exon Structure for
STMND1
ECgene alternative splicing isoforms for
STMND1

Expression for STMND1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for STMND1 Gene

mRNA differential expression in normal tissues according to GTEx for STMND1 Gene

This gene is overexpressed in Testis (x13.4), Pancreas (x8.3), and Fallopian Tube (x6.0).

Protein differential expression in normal tissues from HIPED for STMND1 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (68.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for STMND1 Gene



Protein tissue co-expression partners for STMND1 Gene

NURSA nuclear receptor signaling pathways regulating expression of STMND1 Gene:

STMND1

SOURCE GeneReport for Unigene cluster for STMND1 Gene:

Hs.677399
genes like me logo Genes that share expression patterns with STMND1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for STMND1 Gene

Orthologs for STMND1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for STMND1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC747449 33
  • 97.95 (n)
cow
(Bos Taurus)
Mammalia STMND1 33 34
  • 81.85 (n)
dog
(Canis familiaris)
Mammalia STMND1 33 34
  • 77.24 (n)
mouse
(Mus musculus)
Mammalia Stmnd1 33 16 34
  • 76.24 (n)
rat
(Rattus norvegicus)
Mammalia LOC102554838 33
  • 74.3 (n)
oppossum
(Monodelphis domestica)
Mammalia STMND1 34
  • 53 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CU856207.1 34
  • 28 (a)
OneToOne
Species where no ortholog for STMND1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for STMND1 Gene

ENSEMBL:
Gene Tree for STMND1 (if available)
TreeFam:
Gene Tree for STMND1 (if available)

Paralogs for STMND1 Gene

No data available for Paralogs for STMND1 Gene

Variants for STMND1 Gene

Sequence variations from dbSNP and Humsavar for STMND1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000025158 -- 17,110,649(+) TGTAA(C/G)CTCAG intron-variant
rs1000077463 -- 17,110,981(+) AGACA(A/T)GGTAG intron-variant
rs1000345103 -- 17,104,797(+) CTAGG(C/T)TTGAT intron-variant
rs1000421915 -- 17,117,078(+) GTTTG(-/T)TTTTT intron-variant
rs1000509181 -- 17,102,814(+) AACCT(A/G)TCTGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for STMND1 Gene

Variant ID Type Subtype PubMed ID
esv2664889 CNV deletion 23128226
esv3608206 CNV loss 21293372
nsv5213 CNV deletion 18451855

Variation tolerance for STMND1 Gene

Gene Damage Index Score: 1.93; 35.87% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for STMND1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
STMND1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for STMND1 Gene

Disorders for STMND1 Gene

Relevant External Links for STMND1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
STMND1

No disorders were found for STMND1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for STMND1 Gene

Publications for STMND1 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 60
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 4 60

Products for STMND1 Gene

Sources for STMND1 Gene

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