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STMN4 Gene

protein-coding   GIFtS: 50
GCID: GC08M027092

Stathmin-Like 4

  See STMN4-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Stathmin-Like 41 2
Stathmin-Like Protein B32 3
RB32 3
stathmin-42
Stathmin-Like-Protein RB32

External Ids:    HGNC: 160781   Entrez Gene: 815512   Ensembl: ENSG000000155927   UniProtKB: Q9H1693   

Export aliases for STMN4 gene to outside databases

Previous GC identifers: GC08M026874 GC08M027599 GC08M027115 GC08M027149 GC08M025639


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for STMN4 Gene:
STMN4 (stathmin-like 4) is a protein-coding gene. Diseases associated with STMN4 include exfoliation syndrome. An important paralog of this gene is STMN3.

UniProtKB/Swiss-Prot: STMN4_HUMAN, Q9H169
Function: Exhibits microtubule-destabilizing activity (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NT_167187.2  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the STMN4 gene promoter:
         NF-1   NF-1/L   MAZR   AML1a   CUTL1   POU6F1 (c2)   E4BP4   AREB6   SRY   S8   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTMN4 promoter sequence
   Search Chromatin IP Primers for STMN4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat STMN4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p21.2   Ensembl cytogenetic band:  8p21.2   HGNC cytogenetic band: 8p21.2

STMN4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STMN4 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M027092:  view genomic region     (about GC identifiers)

Start:
27,092,840 bp from pter      End:
27,115,937 bp from pter
Size:
23,098 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: STMN4_HUMAN, Q9H169 (See protein sequence)
Recommended Name: Stathmin-4  
Size: 189 amino acids; 22071 Da
Secondary accessions: D3DSS8 D3DSS9 Q2TAB9
Alternative splicing: 2 isoforms:  Q9H169-1   Q9H169-2   

Explore the universe of human proteins at neXtProt for STMN4: NX_Q9H169

Explore proteomics data for STMN4 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See STMN4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001269982.1  NP_001269983.1  NP_001269984.1  NP_110422.2  

    ENSEMBL proteins: 
     ENSP00000342538   ENSP00000428474   ENSP00000265770   ENSP00000428428   ENSP00000430699  
     ENSP00000430389  

    STMN4 Human Recombinant Protein Products:

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    Novus Biologicals STMN4 Proteins
    Novus Biologicals STMN4 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for STMN4
    Cloud-Clone Corp. Proteins for STMN4

     
    Search eBioscience for Proteins for STMN4 

    STMN4 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    LSBio Antibodies in human, mouse, rat for STMN4

    STMN4 Assay Products:

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    Cloud-Clone Corp. ELISAs for STMN4
    Cloud-Clone Corp. CLIAs for STMN4
    Search eBioscience for ELISAs for STMN4 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR028834 Stathmin-4
     IPR000956 Stathmin_fam

    Graphical View of Domain Structure for InterPro Entry Q9H169

    ProtoNet protein and cluster: Q9H169

    1 Blocks protein domain: IPB000956 Stathmin

    UniProtKB/Swiss-Prot: STMN4_HUMAN, Q9H169
    Similarity: Belongs to the stathmin family
    Similarity: Contains 1 SLD (stathmin-like) domain


    Find genes that share domains with STMN4           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: STMN4_HUMAN, Q9H169
    Function: Exhibits microtubule-destabilizing activity (By similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for STMN4:

     Decreased viability of wild-ty 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for STMN4
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for STMN4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for STMN4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for STMN4

    miRNA
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    Block miRNA regulation of human, mouse, rat STMN4 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate STMN4 (see all 23):
    hsa-miR-21* hsa-miR-485-5p hsa-miR-875-3p hsa-miR-1224-3p hsa-miR-1260b hsa-miR-512-3p hsa-miR-3125 hsa-miR-3916
    SwitchGear 3'UTR luciferase reporter plasmidSTMN4 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for STMN4
    Predesigned siRNA for gene silencing in human, mouse, rat STMN4

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for STMN4

    Clone
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    OriGene clones in human, mouse for STMN4 (see all 9)
    OriGene ORF clones in mouse, rat for STMN4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: STMN4 (NM_030795)
    Sino Biological Human cDNA Clone for STMN4
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for STMN4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STMN4

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    Browse ESI BIO Cell Lines and PureStem Progenitors for STMN4 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STMN4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    STMN4_HUMAN, Q9H169: Golgi apparatus (By similarity). Cell projection, growth cone (By similarity). Cell
    projection, axon (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    extracellular3
    cytoskeleton2
    golgi apparatus2
    lysosome1
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IEA--
    GO:0030424axon IEA--
    GO:0030426growth cone IEA--

    Find genes that share ontologies with STMN4           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for STMN4
    Interactions:

        Search GeneGlobe Interaction Network for STMN4

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5 Interacting proteins for STMN4 (Q9H1692, 3 ENSP000003425384) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IMMTQ168912, 3MINT-65451 I2D: score=5 
    PHIPQ8WWQ02, 3, ENSP000002750344MINT-65452 I2D: score=5 STRING: ENSP00000275034
    TRPC5Q9UL623, ENSP000002628394I2D: score=1 STRING: ENSP00000262839
    PACSIN1Q9BY113I2D: score=2 
    WDR11ENSP000002634614STRING: ENSP00000263461
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031110regulation of microtubule polymerization or depolymerization IEA--

    Find genes that share ontologies with STMN4           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for STMN4

    2 DrugBank Compounds for STMN4    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    LomustineCCNU (see all 4)13010-47-4targetantagonist18162179 18593927
    2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE-- --target--10592235



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for STMN4 gene (4 alternative transcripts): 
    NM_001283053.1  NM_001283054.1  NM_001283055.1  NM_030795.3  

    Unigene Cluster for STMN4:

    Stathmin-like 4
    Hs.201058  [show with all ESTs]
    Unigene Representative Sequence: AK295329
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000350889(uc003xfj.3 uc011lai.2 uc003xfk.3) ENST00000519997(uc011laj.2)
    ENST00000265770 ENST00000523048 ENST00000519614(uc011lak.2 uc010luo.3)
    ENST00000522908 ENST00000522750
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat STMN4 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate STMN4 (see all 23):
    hsa-miR-21* hsa-miR-485-5p hsa-miR-875-3p hsa-miR-1224-3p hsa-miR-1260b hsa-miR-512-3p hsa-miR-3125 hsa-miR-3916
    SwitchGear 3'UTR luciferase reporter plasmidSTMN4 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for STMN4
    Predesigned siRNA for gene silencing in human, mouse, rat STMN4
    Clone
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    OriGene clones in human, mouse for STMN4 (see all 9)
    OriGene ORF clones in mouse, rat for STMN4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: STMN4 (NM_030795)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for STMN4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STMN4
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for STMN4
    OriGene qSTAR qPCR primer pairs in human, mouse for STMN4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat STMN4
      QuantiTect SYBR Green Assays in human, mouse, rat STMN4
      QuantiFast Probe-based Assays in human, mouse, rat STMN4

    Additional mRNA sequence: 

    AJ303455.1 AK225142.1 AK294023.1 AK295329.1 AK297415.1 AK309207.1 AL136568.1 BC011520.1 
    BC111001.1 

    5 DOTS entries:

    DT.453623  DT.86847235  DT.95070010  DT.100779700  DT.75196092 

    Selected AceView cDNA sequences (see all 129):

    BI753462 AJ303455 CR591479 BE551697 BC011520 AL539699 T08783 AL136568 
    NM_030795 BM544782 AW341050 AI815865 BQ892309 AA297794 AW161604 AW297089 
    AI929334 T33587 BM725992 AI886949 BM700315 BP347349 AA902212 AI638208 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for STMN4 (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c
    SP1:                    -                       -                 -                     
    SP2:                    -     -                 -                 -                     
    SP3:                    -     -                 -                                       
    SP4:              -     -     -     -           -                 -                     
    SP5:                                            -                                       


    ECgene alternative splicing isoforms for STMN4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    STMN4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCAATGAAA
    STMN4 Expression
    About this image


    STMN4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 9 entries
             Endothelial Cells Blood Brain Barrier
             Cerebral Cortex
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Mononuclear Myocytes Hyoid Arch Muscles
     
     Endothelium (Cardiovascular System)
             Endothelial Cells Blood Brain Barrier
    STMN4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    STMN4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.201058
        Custom PCR Arrays for STMN4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for STMN4
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    QuantiFast Probe-based Assays in human, mouse, rat STMN4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STMN4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for STMN4 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Stmn41 , 5 stathmin-like 41, 5 88.36(n)1
    99.47(a)1
      14 (34.48 cM)5
    564711  NM_019675.21  NP_062649.11 
     663442965 
    chicken
    (Gallus gallus)
    Aves STMN41 stathmin-like 4 82.72(n)
    96.3(a)
      422010  XM_004935867.1  XP_004935924.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia stmn4-prov2 stathmin-like 4 78.19(n)    BC054158.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufj44e062 Danio rerio cDNA clone MGC73243 IMAGE4146605, complete cds less 78.16(n)    BC059583.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta stai6
    stathmin
    17(a)
    1 → many
    2L(6100377-6124653)


    ENSEMBL Gene Tree for STMN4 (if available)
    TreeFam Gene Tree for STMN4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for STMN4 gene
    STMN32  STMN22  STMN12  
    3 SIMAP similar genes for STMN4 using alignment to 5 protein entries:     STMN4_HUMAN (see all proteins):
    STMN1    STMN2    STMN3

    Find genes that share paralogs with STMN4           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for STMN4 (see all 502)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1848206011,2
    --27093325(+) AAAAGA/GCATCA 1 -- int10--------
    rs1893621791,2
    C--27093430(+) TCTGTC/TATCAA 1 -- int10--------
    rs1413018071,2
    C--27093474(+) TGAACA/GGTTGT 1 -- int10--------
    rs47330371,2
    C,F,A,H--27093495(+) AATTCC/TTTCTT 1 -- int125Minor allele frequency- T:0.35NS EA NA WA CSA 2490
    rs1816571761,2
    C--27093648(+) ATTATG/TCCAAA 1 -- int10--------
    rs1859460881,2
    --27093741(+) AGATGG/TATGAA 1 -- int10--------
    rs285264411,2
    C,F--27093760(+) TTCGAG/TAACTT 1 -- int17Minor allele frequency- T:0.19NA WA CSA EA 365
    rs1914343971,2
    --27093811(+) CTGGAC/TACTTG 1 -- int10--------
    rs1404265071,2
    C--27093860(+) TGGTT-/CACACAC 1 -- ut310--------
    rs47330381,2
    C,F,A,H--27093924(+) TCACAC/ACCCCT 1 -- ut3127Minor allele frequency- A:0.16NA NS EA WA CSA 2482

    HapMap Linkage Disequilibrium report for STMN4 (27092840 - 27115937 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for STMN4:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv6131CNV Loss18451855
    nsv831274CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing STMN4
    DNA2.0 Custom Variant and Variant Library Synthesis for STMN4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for STMN4:    
    About MalaCards
    exfoliation syndrome

    1 disease from the University of Copenhagen DISEASES database for STMN4:
    Exfoliation syndrome

    Find genes that share disorders with STMN4           About GenesLikeMe


    Export disorders for STMN4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for STMN4 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with STMN4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network. (PubMed id 9788875)1, 9 Gavet O....Sobel A. (J. Cell. Sci. 1998)
    4. Expression of stathmin family genes in human tissues: non-neural- restricted expression for SCLIP. (PubMed id 12676564)1, 9 Bieche I.... Curmi P.A. (Genomics 2003)
    5. Nitrosoureas inhibit the stathmin-mediated migration and invasion of malignant glioma cells. (PubMed id 18593927)7 Liang X.J....Park J.K. (Cancer Res. 2008)
    6. Covalent modification of stathmin by CCNU determined by FTMS analysis of modified proteins and tryptic peptides. (PubMed id 18162179)7 Wu W.W....Shen R.F. (Biochem. Biophys. Res. Commun. 2008)
    7. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (Cell 2005)
    8. TRPC5 is a regulator of hippocampal neurite length and growth cone morphology. (PubMed id 12858178)1 Greka A....Clapham D.E. (Nat. Neurosci. 2003)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. The Protein Data Bank. (PubMed id 10592235)7 Berman H.M....Bourne P.E. (Nucleic Acids Res. 2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 81551 HGNC: 16078 AceView: STMN4 Ensembl:ENSG00000015592 euGenes: HUgn81551
    ECgene: STMN4 H-InvDB: STMN4

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for STMN4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for STMN4 gene:
    Search GeneIP for patents involving STMN4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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