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STMN3 Gene

protein-coding GIFtS: 51
GCID: GC20M062271

Stathmin-Like 3

See related diseases
at

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Stathmin-Like 3¹ ²
SCLIP² ³ ⁵
SCG10-Like Protein² ³
SCG10-like-protein²
stathmin-3²

External Ids:	HGNC: 15926¹	Entrez Gene: 50861²	Ensembl: ENSG00000197457⁷	OMIM: 608362⁵	UniProtKB: Q9NZ72³

ORGUL members:

Export aliases for STMN3 gene to outside databases

Previous GC identifers: GC20M062148 GC20M062950 GC20M062998 GC20M062999 GC20M061741 GC20M059001

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for STMN3 Gene:

This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form

a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered

assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and

function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple

transcript variants. (provided by RefSeq, Jan 2013)

GeneCards Summary for STMN3 Gene:

STMN3 (stathmin-like 3) is a protein-coding gene. Diseases associated with STMN3 include ulcerative colitis, and lung cancer. GO annotations related to this gene include protein domain specific binding. An important paralog of this gene is STMN2.

UniProtKB/Swiss-Prot: STMN3_HUMAN, Q9NZ72

Function: Exhibits microtubule-destabilizing activity, which is antagonized by STAT3 (By similarity)

Gene Wiki entry for STMN3 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000020.11 NC_018931.2 NT_011362.11

Regulatory elements:

Regulatory transcription factor binding sites in the STMN3 gene promoter:
AP-1 ATF-2 NRSF form 1 NRSF form 2 ARP-1 c-Jun NF-kappaB1 Ik-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: STMN3 promoter sequence

Search Chromatin IP Primers for STMN3

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat STMN3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.3 Ensembl cytogenetic band: 20q13.33 HGNC cytogenetic band: 20q13.3

STMN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STMN3 gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20M062271: view genomic region (about GC identifiers)

Start:	62,271,061 bp from pter	End:	62,284,780 bp from pter
Size:	13,720 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: STMN3_HUMAN, Q9NZ72 (See protein sequence)

Recommended Name: Stathmin-3

Size: 180 amino acids; 21017 Da

Subunit: Interacts with STAT3 (By similarity)

Secondary accessions: B3KSQ5 B7WP52 O75527 Q969Y4

Explore the universe of human proteins at neXtProt for STMN3: NX_Q9NZ72

Explore proteomics data for STMN3 at MOPED

Post-translational modifications:

N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent

vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases

ZDHHC3, ZDHHC7 and ZDHHC15¹

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See STMN3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts):

NP_001263239.1 NP_056978.2

ENSEMBL proteins:

ENSP00000359070 ENSP00000439840

STMN3 Human Recombinant Protein Products:

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STMN3 Antibody Products:

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	Abcam antibodies for STMN3
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	Search ThermoFisher Antibodies for STMN3
	LSBio Antibodies in human, mouse, rat for STMN3

STMN3 Assay Products:

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	Cloud-Clone Corp. ELISAs for STMN3 Cloud-Clone Corp. CLIAs for STMN3

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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2 InterPro protein domains:

IPR028835 Stathmin-3

IPR000956 Stathmin_fam

Graphical View of Domain Structure for InterPro Entry Q9NZ72

ProtoNet protein and cluster: Q9NZ72

1 Blocks protein domain: IPB000956 Stathmin

UniProtKB/Swiss-Prot: STMN3_HUMAN, Q9NZ72

Similarity: Belongs to the stathmin family

Similarity: Contains 1 SLD (stathmin-like) domain

STMN3 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: STMN3_HUMAN, Q9NZ72

Function: Exhibits microtubule-destabilizing activity, which is antagonized by STAT3 (By similarity)

Gene Ontology (GO): 2 molecular function terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--
GO:0019904	protein domain specific binding	ISS	--

STMN3 for ontologies About GeneDecksing

Phenotypes:
1 MGI phenotypic allele

for Stmn3 (no phenotypes)

STMN3 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for STMN3

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for STMN3

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for STMN3

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for STMN3

miRNA Products:		miRTarBase miRNAs that target STMN3: hsa-mir-106b-3p (MIRT038576), hsa-mir-197-3p (MIRT048052), hsa-mir-92a-3p (MIRT049539), hsa-mir-1260b (MIRT052675)

		Block miRNA regulation of human, mouse, rat STMN3 using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate STMN3 (see all 12):
		hsa-miR-125a-5p hsa-miR-330-5p hsa-miR-4305 hsa-miR-3126-5p hsa-miR-637 hsa-miR-320e hsa-miR-125b hsa-miR-1255a

		SwitchGear 3'UTR luciferase reporter plasmid: STMN3 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for STMN3
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Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for STMN3

Clone Products:		OriGene clones in human, mouse for STMN3 (see all 6) OriGene ORF clones in mouse, rat for STMN3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STMN3

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

STMN3_HUMAN, Q9NZ72: Golgi apparatus. Cell projection, growth cone. Cell projection, axon

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
golgi apparatus	5
cytosol	3
extracellular	2
nucleus	2
cytoskeleton	1

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Gene Ontology (GO): 4 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	ISS	--
GO:0005794	Golgi apparatus	IEA	--
GO:0030424	axon	IEA	--
GO:0030426	growth cone	IEA	--

STMN3 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for STMN3
Interactions:

GeneGlobe Interaction Network for STMN3

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

Selected Interacting proteins for STMN3 (Q9NZ72^{2, 3} ENSP00000359070⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 9)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SPCS2	Q15005²^,³, ENSP00000263672⁴	MINT-64586 I2D: score=4 STRING: ENSP00000263672
TRPC5	Q9UL62³, ENSP00000262839⁴	I2D: score=1 STRING: ENSP00000262839
STAT3	P40763³	I2D: score=1
CDKN1B	ENSP00000228872⁴	STRING: ENSP00000228872
UBQLN1	ENSP00000365576⁴	STRING: ENSP00000365576

About this table

Gene Ontology (GO): Selected biological process terms (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007399	nervous system development	TAS	9603203
GO:0031110	regulation of microtubule polymerization or depolymerization	IEA	--
GO:0031122	cytoplasmic microtubule organization	ISS	--
GO:0031175	neuron projection development	ISS	--
GO:0032314	regulation of Rac GTPase activity	ISS	--

STMN3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for STMN3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for STMN3 gene (2 alternative transcripts):

NM_001276310.1 NM_015894.3

Unigene Cluster for STMN3:

Stathmin-like 3

Hs.639609 [show with all ESTs]

Unigene Representative Sequence: AK094112

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000370053(uc002yfr.1 uc021wgd.1) ENST00000540534

miRNA Products:		Block miRNA regulation of human, mouse, rat STMN3 using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate STMN3 (see all 12):
		hsa-miR-125a-5p hsa-miR-330-5p hsa-miR-4305 hsa-miR-3126-5p hsa-miR-637 hsa-miR-320e hsa-miR-125b hsa-miR-1255a

		SwitchGear 3'UTR luciferase reporter plasmid: STMN3 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for STMN3
		Predesigned siRNA for gene silencing in human, mouse, rat STMN3

Clone Products:		OriGene clones in human, mouse for STMN3 (see all 6) OriGene ORF clones in mouse, rat for STMN3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: STMN3 (NM_015894)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for STMN3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STMN3

Primer Products:		OriGene qPCR primer pairs and template standards for STMN3 OriGene qSTAR qPCR primer pairs in human, mouse for STMN3
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat STMN3
		QuantiTect SYBR Green Assays in human, mouse, rat STMN3
		QuantiFast Probe-based Assays in human, mouse, rat STMN3

Additional mRNA sequence:

AF069709.1 AK074860.1 AK094112.1 AK131326.1 AK298903.1 AK310010.1 BC009381.2 BC025234.1

BC032527.2 BC047671.1 BC056873.1 BC082248.1 NR_075070.1

Selected DOTS entries (see all 37):

DT.95221068 DT.91923680 DT.120824905 DT.100881763 DT.120825003 DT.100881781 DT.216374 DT.95167293

DT.97778886 DT.100881764 DT.92442515 DT.120825149 DT.100654203 DT.100881755 DT.100881782 DT.120825167

DT.95167292 DT.100653716 DT.100881751 DT.100799518 DT.100841540 DT.100881748 DT.100830030 DT.120825092

Selected AceView cDNA sequences (see all 441):

BI907319 BU174076 BU173238 BE382679 BM849490 BQ691840 AA937338 AA326588

AA938574 BQ674610 BQ686291 CR623033 BX355971 BQ890569 BM543191 BQ689216

BI820424 BQ687549 T33212 BQ687104 CR614160 BM846139 BQ639606 AA746245

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for STMN3 About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	^	5	^	6a	·	6b	·	6c
SP1:					-						-				-
SP2:					-						-
SP3:					-
SP4:

ECgene alternative splicing isoforms for STMN3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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STMN3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GTGGCAGCGC

About this image

STMN3 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 8) fully expand


Skeletal Muscle (Muscoskeletal System) fully expand to see all 6 entries
Mononuclear Myocytes Hyoid Arch Muscles

Brain (Nervous System) fully expand to see all 6 entries
Cerebral Cortex

Neural Tube (Nervous System) fully expand to see all 3 entries
Metencephalon

Inner Cell Mass (Early Embryonic Tissues) fully expand to see all 2 entries
Human embryonic stem cells (family)

Thymus (Hematopoietic System)
Thymus

STMN3 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

STMN3 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.639609

UniProtKB/Swiss-Prot: STMN3_HUMAN, Q9NZ72

Tissue specificity: Neuron specific

Custom PCR Arrays for STMN3

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		QuantiFast Probe-based Assays in human, mouse, rat STMN3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STMN3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for STMN3 gene from Selected species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Stmn3^{1 , 5}	stathmin-like 3^{1, 5}	89.07(n)¹ 96.11(a)¹		2 (103.63 cM)⁵ 20262¹ NM_009133.3¹ NP_033159.1¹ 181306459⁵
chicken (Gallus gallus)	Aves	STMN3¹	stathmin-like 3	86.3(n) 93.89(a)		419263 NM_001004393.1 NP_001004393.1
lizard (Anolis carolinensis)	Reptilia	STMN3⁶	stathmin-like 3	85(a)	1 ↔ 1	GL343401.1(701644-791417)
African clawed frog (Xenopus laevis)	Amphibia	stmn3-prov²	stathmin-like 3	75.95(n)		BC041517.1
zebrafish (Danio rerio)	Actinopterygii	LOC798970¹	stathmin-3-like	70.74(n) 66.67(a)		798970 XM_001339340.5 XP_001339376.4
fruit fly (Drosophila melanogaster)	Insecta	stai⁶	stathmin	14(a)	1 → many	2L(6100377-6124653)

ENSEMBL Gene Tree for STMN3 (if available)
TreeFam Gene Tree for STMN3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for STMN3 gene

STMN2² STMN4² STMN1²

3 SIMAP similar genes for STMN3 using alignment to 2 protein entries: STMN3_HUMAN (see all proteins):

STMN1 STMN2 STMN4

STMN3 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for STMN3
PGOHUM00000246294

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs116084451^1,2	C,F	--	62244477(+)	`GCCACG/TTGGCA`	1	--	us2k¹		1		WA	118
rs909333^1,2	C,F,A,H	--	62270637(+)	`CCCCAT/GGTCAG`	3	--	ds500¹		8		NA EA	364
rs139197621^1,2		--	62270692(+)	`GTAGGC/TCCTGC`	3	--	ds500¹		0	--	--	--	--
rs914561^1,2	C,F,A,H	--	62270905(+)	`ATCACC/TGTTGT`	3	--	ds500¹		33		NS EA NA WA CSA	2919
rs909334^1,2	C,F,O,H	--	62270930(+)	`ATAATC/AATGAT`	3	--	ds500¹		24		MN EA NA NS WA	2742
rs187425145^1,2		--	62271104(+)	`TTGATA/TGAATT`	3	--	ut3¹ nc-transcript-variant		0	--	--	--	--
rs11545510^1,2	C	--	62271146(-)	`TAATAT/CGCACC`	3	--	ut3¹ nc-transcript-variantese³		2		NA	4
rs116444123^1,2	C,F	--	62271187(+)	`ATGAGG/AAATAT`	3	--	ut3¹ nc-transcript-variant		1		WA	118
rs1059250^1,2	C,F,A,H	--	62271380(-)	`CAGAGC/TCACAC`	3	--	ut3¹ nc-transcript-variantese³		14		MN NA WA CSA EA	559
rs114015203^1,2	C,F	--	62271396(+)	`CACTGG/ACAGTG`	3	--	ut3¹ nc-transcript-variant		1		WA	118

HapMap Linkage Disequilibrium report for STMN3 (62271061 - 62284780 bp)

Structural Variations
Database of Genomic Variants (DGV) Selected variations for STMN3 (see all 12): About this table

Variant ID	Type	Subtype	PubMed ID
dgv4644n71	CNV	Loss	21882294
nsv470563	CNV	Loss	18288195
nsv913213	CNV	Loss	21882294
nsv913190	CNV	Loss	21882294
dgv4618n71	CNV	Loss	21882294
nsv913241	CNV	Loss	21882294
nsv913240	CNV	Loss	21882294
dgv4641n71	CNV	Loss	21882294
nsv9827	CNV	Loss	18304495
nsv428381	CNV	Gain+Loss	18775914

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing STMN3

DNA2.0 Custom Variant and Variant Library Synthesis for STMN3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 608362 OMIM disorders: --

5 diseases for STMN3:
About MalaCards

ulcerative colitis lung cancer neuronitis cerebritis

breast cancer

STMN3 for disorders About GeneDecksing

Export disorders for STMN3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for STMN3 gene, integrated from 10 sources (see all 35):
(articles sorted by number of sources associating them with STMN3)

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Overexpression of M68/DcR3 in human gastrointestinal tract tumors independent of gene amplification and its location in a four-gene cluster. (PubMed id 10655513)^{1, 2, 3} Bai C.... Caskey C.T. (Proc. Natl. Acad. Sci. U.S.A. 2000)
SCLIP: a novel SCG10-like protein of the stathmin family expressed in the nervous system. (PubMed id 9603203)^{1, 2, 3} Ozon S.... Sobel A. (J. Neurochem. 1998)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (Nature 2001)
SCG10-like protein (SCLIP) is a STAT3-interacting protein involved in maintaining epithelial morphology in MCF-7 breast cancer cells. (PubMed id 19824884)^{1, 9} Ng D.C....Cao X. (Biochem. J. 2010)
The trans-Golgi proteins SCLIP and SCG10 interact with chromogranin A to regulate neuroendocrine secretion. (PubMed id 18549247)^{1, 9} Mahapatra N.R....O'Connor D.T. (Biochemistry 2008)
Expression of stathmin family genes in human tissues: non-neural- restricted expression for SCLIP. (PubMed id 12676564)^{1, 9} Bieche I.... Curmi P.A. (Genomics 2003)
Stathmin family proteins display specific molecular and tubulin binding properties. (PubMed id 11278715)^{1, 9} Charbaut E....Sobel A. (J. Biol. Chem. 2001)
The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network. (PubMed id 9788875)^{1, 9} Gavet O....Sobel A. (J. Cell. Sci. 1998)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 50861	HGNC: 15926	AceView: STMN3	Ensembl:ENSG00000197457	euGenes: HUgn50861
ECgene: STMN3	H-InvDB: STMN3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for STMN3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for STMN3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for STMN3 gene:
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