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Aliases for STKLD1 Gene

Aliases for STKLD1 Gene

  • Serine/Threonine Kinase-Like Domain Containing 1 2 3
  • Serine/Threonine Kinase-Like Domain-Containing Protein 1 3 4
  • Sugen Kinase 071 3 4
  • C9orf96 3 4
  • SgK071 3 4
  • Serine/Threonine Kinase-Like Domain-Containing Protein STKLD1 3
  • Probable Inactive Protein Kinase-Like Protein SgK071 3
  • Chromosome 9 Open Reading Frame 96 2
  • Sk521 3

External Ids for STKLD1 Gene

Previous HGNC Symbols for STKLD1 Gene

  • C9orf96

Summaries for STKLD1 Gene

GeneCards Summary for STKLD1 Gene

STKLD1 (Serine/Threonine Kinase-Like Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STKLD1 Gene

Genomics for STKLD1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for STKLD1 Gene

133,376,367 bp from pter
133,406,096 bp from pter
29,730 bases
Plus strand

Genomic View for STKLD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for STKLD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STKLD1 Gene

No data available for Regulatory Elements for STKLD1 Gene

Proteins for STKLD1 Gene

  • Protein details for STKLD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Serine/threonine kinase-like domain-containing protein STKLD1
    Protein Accession:
    Secondary Accessions:
    • Q5T8U8
    • Q6ZMP6
    • Q6ZMQ5

    Protein attributes for STKLD1 Gene

    680 amino acids
    Molecular mass:
    75676 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for STKLD1 Gene


neXtProt entry for STKLD1 Gene

Proteomics data for STKLD1 Gene at MOPED

Post-translational modifications for STKLD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for STKLD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for STKLD1 Gene

Domains for STKLD1 Gene

Protein Domains for STKLD1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q8NE28
  • The protein kinase domain is predicted to be catalytically inactive
  • Contains 1 protein kinase domain.
  • Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.
genes like me logo Genes that share domains with STKLD1: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for STKLD1 Gene

Function for STKLD1 Gene

Gene Ontology (GO) - Molecular Function for STKLD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004672 protein kinase activity IEA --
GO:0004713 protein tyrosine kinase activity --
GO:0005488 binding --
GO:0005524 ATP binding IEA --
GO:0016772 transferase activity, transferring phosphorus-containing groups --
genes like me logo Genes that share ontologies with STKLD1: view

Phenotypes for STKLD1 Gene

genes like me logo Genes that share phenotypes with STKLD1: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for STKLD1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for STKLD1 Gene

Localization for STKLD1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for STKLD1 Gene

Pathways for STKLD1 Gene

SuperPathways for STKLD1 Gene

No Data Available

Interacting Proteins for STKLD1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000361025 for STKLD1 Gene via STRING

Gene Ontology (GO) - Biological Process for STKLD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006468 protein phosphorylation IEA --
genes like me logo Genes that share ontologies with STKLD1: view

No data available for Pathways by source for STKLD1 Gene

Transcripts for STKLD1 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for STKLD1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for STKLD1 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15
SP1: - - -
SP3: - - - - -

Relevant External Links for STKLD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for STKLD1 Gene

mRNA expression in normal human tissues for STKLD1 Gene

genes like me logo Genes that share expressions with STKLD1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for STKLD1 Gene

Orthologs for STKLD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for STKLD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C11H9orf96 35
  • 77.33 (n)
  • 67.7 (a)
C9orf96 36
  • 67 (a)
(Canis familiaris)
Mammalia C9H9orf96 35
  • 80.45 (n)
  • 71.63 (a)
C9orf96 36
  • 69 (a)
(Mus musculus)
Mammalia Gm711 35
  • 72.94 (n)
  • 62.34 (a)
Gm711 16
Gm711 36
  • 59 (a)
(Pan troglodytes)
Mammalia LOC746554 35
  • 99.04 (n)
  • 98.71 (a)
C9orf96 36
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1307355 35
  • 70.79 (n)
  • 58.73 (a)
(Monodelphis domestica)
Mammalia C9orf96 36
  • 45 (a)
(Ornithorhynchus anatinus)
Mammalia C9orf96 36
  • 40 (a)
(Gallus gallus)
Aves C17H9ORF96 35
  • 51.97 (n)
  • 38.93 (a)
C9orf96 36
  • 38 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 31 (a)
-- 36
  • 29 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100491915 35
  • 49.08 (n)
  • 33.39 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2639 36
  • 22 (a)
Species with no ortholog for STKLD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for STKLD1 Gene

Gene Tree for STKLD1 (if available)
Gene Tree for STKLD1 (if available)

Paralogs for STKLD1 Gene

No data available for Paralogs for STKLD1 Gene

Variants for STKLD1 Gene

Sequence variations from dbSNP and Humsavar for STKLD1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs943623 -- 133,402,242(-) GCTGG(A/C)GGCTT intron-variant
rs2148994 -- 133,405,301(-) ATCTC(C/T)TGGAG synonymous-codon, reference, nc-transcript-variant
rs3118661 -- 133,385,242(+) TCTCC(A/G)TGTGC intron-variant
rs3124747 -- 133,402,955(-) GCTTT(C/T)GAGGG missense, reference, intron-variant
rs3124748 -- 133,402,909(-) CCAGC(A/G)TTCTG synonymous-codon, reference, intron-variant

Relevant External Links for STKLD1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for STKLD1 Gene

Disorders for STKLD1 Gene

No disorders were found for STKLD1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for STKLD1 Gene

Publications for STKLD1 Gene

  1. The protein kinase complement of the human genome. (PMID: 12471243) Manning G. … Sudarsanam S. (Science 2002) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for STKLD1 Gene

Sources for STKLD1 Gene

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