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Aliases for STKLD1 Gene

Aliases for STKLD1 Gene

  • Serine/Threonine Kinase-Like Domain Containing 1 2 3 5
  • Serine/Threonine Kinase-Like Domain-Containing Protein 1 3 4
  • Sugen Kinase 071 3 4
  • C9orf96 3 4
  • SgK071 3 4
  • Probable Inactive Protein Kinase-Like Protein SgK071 3
  • Chromosome 9 Open Reading Frame 96 2
  • Sk521 3

External Ids for STKLD1 Gene

Previous HGNC Symbols for STKLD1 Gene

  • C9orf96

Summaries for STKLD1 Gene

GeneCards Summary for STKLD1 Gene

STKLD1 (Serine/Threonine Kinase-Like Domain Containing 1) is a Protein Coding gene. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for STKLD1 Gene

Genomics for STKLD1 Gene

Regulatory Elements for STKLD1 Gene

Enhancers for STKLD1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around STKLD1 on UCSC Golden Path with GeneCards custom track

Promoters for STKLD1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around STKLD1 on UCSC Golden Path with GeneCards custom track

Genomic Location for STKLD1 Gene

133,376,367 bp from pter
133,406,096 bp from pter
29,730 bases
Plus strand

Genomic View for STKLD1 Gene

Genes around STKLD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
STKLD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for STKLD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for STKLD1 Gene

Proteins for STKLD1 Gene

  • Protein details for STKLD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Serine/threonine kinase-like domain-containing protein STKLD1
    Protein Accession:
    Secondary Accessions:
    • Q5T8U8
    • Q6ZMP6
    • Q6ZMQ5

    Protein attributes for STKLD1 Gene

    680 amino acids
    Molecular mass:
    75676 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for STKLD1 Gene


neXtProt entry for STKLD1 Gene

Proteomics data for STKLD1 Gene at MOPED

Post-translational modifications for STKLD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for STKLD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for STKLD1 Gene

Domains & Families for STKLD1 Gene

Protein Domains for STKLD1 Gene

Suggested Antigen Peptide Sequences for STKLD1 Gene

Graphical View of Domain Structure for InterPro Entry



  • The protein kinase domain is predicted to be catalytically inactive.
  • Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.
  • The protein kinase domain is predicted to be catalytically inactive.
  • Contains 1 protein kinase domain.
  • Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.
genes like me logo Genes that share domains with STKLD1: view

No data available for Gene Families for STKLD1 Gene

Function for STKLD1 Gene

Gene Ontology (GO) - Molecular Function for STKLD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005488 binding IEA --
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with STKLD1: view
genes like me logo Genes that share phenotypes with STKLD1: view

Animal Model Products

  • Taconic Biosciences Mouse Models for STKLD1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for STKLD1 Gene

Localization for STKLD1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for STKLD1 Gene

Pathways & Interactions for STKLD1 Gene

SuperPathways for STKLD1 Gene

No Data Available

Interacting Proteins for STKLD1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000361025 for STKLD1 Gene via STRING

Gene Ontology (GO) - Biological Process for STKLD1 Gene


No data available for Pathways by source and SIGNOR curated interactions for STKLD1 Gene

Drugs & Compounds for STKLD1 Gene

No Compound Related Data Available

Transcripts for STKLD1 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for STKLD1 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15
SP1: - - -
SP3: - - - - -

Relevant External Links for STKLD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for STKLD1 Gene

mRNA expression in normal human tissues for STKLD1 Gene

genes like me logo Genes that share expression patterns with STKLD1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for STKLD1 Gene

Orthologs for STKLD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for STKLD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C11H9orf96 35
  • 77.33 (n)
  • 67.7 (a)
C9orf96 36
  • 67 (a)
(Canis familiaris)
Mammalia C9H9orf96 35
  • 80.45 (n)
  • 71.63 (a)
C9orf96 36
  • 69 (a)
(Mus musculus)
Mammalia Gm711 35
  • 72.94 (n)
  • 62.34 (a)
Stkld1 16
Gm711 36
  • 59 (a)
(Pan troglodytes)
Mammalia LOC746554 35
  • 99.04 (n)
  • 98.71 (a)
C9orf96 36
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1307355 35
  • 70.79 (n)
  • 58.73 (a)
(Monodelphis domestica)
Mammalia C9orf96 36
  • 45 (a)
(Ornithorhynchus anatinus)
Mammalia C9orf96 36
  • 40 (a)
(Gallus gallus)
Aves C17H9ORF96 35
  • 51.97 (n)
  • 38.93 (a)
C9orf96 36
  • 38 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 31 (a)
-- 36
  • 29 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100491915 35
  • 49.08 (n)
  • 33.39 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2639 36
  • 22 (a)
Species with no ortholog for STKLD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for STKLD1 Gene

Gene Tree for STKLD1 (if available)
Gene Tree for STKLD1 (if available)

Paralogs for STKLD1 Gene

No data available for Paralogs for STKLD1 Gene

Variants for STKLD1 Gene

Sequence variations from dbSNP and Humsavar for STKLD1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs3124747 - 133,402,955(-) GCTTT(C/G/T)GAGGG intron-variant, reference, missense
rs17150554 - 133,404,019(+) CTACC(A/G)GGGAC nc-transcript-variant, reference, missense
VAR_041371 A glioblastoma multiforme sample
rs943623 -- 133,402,242(-) GCTGG(A/C)GGCTT intron-variant
rs113081038 -- 133,391,530(+) AATTC(C/T)TCTGC intron-variant

Variation tolerance for STKLD1 Gene

Residual Variation Intolerance Score: 63.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.50; 77.62% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for STKLD1 Gene

Disorders for STKLD1 Gene

Relevant External Links for STKLD1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for STKLD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for STKLD1 Gene

Publications for STKLD1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  5. Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association. (PMID: 23267103) Desch K.C. … Ginsburg D. (Proc. Natl. Acad. Sci. U.S.A. 2013) 3

Products for STKLD1 Gene

Sources for STKLD1 Gene