Aliases for STK39 Gene
External Ids for STK39 Gene
Previous GeneCards Identifiers for STK39 Gene
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]
GeneCards Summary for STK39 Gene
STK39 (Serine Threonine Kinase 39) is a Protein Coding gene. Diseases associated with STK39 include glanders. Among its related pathways are Cytoskeletal Signaling and Glucose / Energy Metabolism. GO annotations related to this gene include protein kinase binding and receptor signaling protein serine/threonine kinase activity. An important paralog of this gene is OXSR1.
UniProtKB/Swiss-Prot for STK39 Gene
May act as a mediator of stress-activated signals