STK36 Gene
protein-coding GIFtS : 61
GCID: GC02 P219536
serine/threonine kinase 36 (Previous names: serine/threonine kinase 36 (fused homolog, Drosophila)... )
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Aliasesfor STK36 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Serine/Threonine Kinase 36 1 2 EC 2.7.11.13 8 FU1 2 5 Serine/Threonine Kinase 36 (Fused Homolog, Drosophila)1 KIAA12781 3 5 Serine/Threonine-Protein Kinase 362 Fused Homolog2 3 EC 2.7.118
Export aliases for STK36 gene to outside databases Previous GC identifers: GC02P217552 GC02P218258 GC02P219500 GC02P219739 GC02P219362 GC02P219245 GC02P211390
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Summariesfor STK36 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for STK36 : This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. (provided by RefSeq, Aug 2011) UniProtKB/Swiss-Prot: STK36_HUMAN, Q9NRP7 Function : Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway byregulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia Gene Wiki entry for STK36
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Viewsfor STK36 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000002.11 NC_018913.1 NT_005403.17 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the STK36 gene promoter: E2F-3a E2F-4 GR AP-1 p53 GR-beta ATF-2 CREB deltaCREB GR-alpha Other transcription factors Search SABiosciences Chromatin IP Primers for STK36 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat STK36
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 2q35 Ensembl cytogenetic band: 2q35 HGNC cytogenetic band: 2q35 STK36 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 2 GeneLoc Exon Structure
GeneLoc location for GC02P219536: view genomic region
(about GC identifiers )
Start:
219,536,749 bp from pter
End:
219,567,440 bp from pter
Size:
30,692 bases
Orientation:
plus strand
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Proteinsfor STK36 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: STK36_HUMAN, Q9NRP7 (See
protein sequence )Recommended Name: Serine/threonine-protein kinase 36 Size : 1315 amino acids; 143995 Da
Cofactor : Magnesium
Subunit : Interacts with SPAG16 and KIF27 (By similarity)
Subcellular location : Cytoplasm. Nucleus. Note=Low levels also present in the nucleus
Sequence caution : Sequence=BAA86592.1; Type=Erroneous initiation; Sequence=BAB14184.1; Type=Frameshift; Positions=987;
Secondary accessions : B7WPM3 Q8TC32 Q9H9N9 Q9UF35 Q9ULE2Alternative splicing : 2 isoforms : Q9NRP7-1 Q9NRP7-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for STK36: NX_Q9NRP7 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9NRP7 4 DME Specific Peptides for STK36 (Q9NRP7 ) STK36 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins (2 alternative transcripts):
NP_001230242.1 NP_056505.2 ENSEMBL proteins: ENSP00000295709 ENSP00000375954 ENSP00000400055 ENSP00000394095 ENSP00000403527 ENSP00000406184 ENSP00000409688 ENSP00000416372 ENSP00000404719 ENSP00000375955 Human Recombinant Protein Products: Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view) : About this table
STK36 for ontologies About GeneDecksing STK36 Antibody Products: Assay Products for STK36:
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Protein
Domains / Familiesfor STK36 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
STK36 for domains About GeneDecksing 5/7 InterPro domains/families (see all 7 ):
Graphical View of Domain Structure for InterPro Entry Q9NRP7 ProtoNet protein and cluster: Q9NRP7
1 Blocks protein family : IPB000357 HEAT repeat UniProtKB/Swiss-Prot: STK36_HUMAN, Q9NRP7 Similarity : Belongs to the protein kinase superfamily. Ser/Thr protein kinase familySimilarity : Contains 1 protein kinase domain
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Functionfor STK36 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: STK36_HUMAN, Q9NRP7 Function : Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway byregulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia Catalytic activity : ATP + a protein = ADP + a phosphoproteinEnzyme Numbers (IUBMB): EC 2.7.11.1 1 2 EC 2.7.11 2
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for STK36 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for STK36OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: STK36 (NM_015690 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for STK36 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat STK36
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STK36
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6 ): About this table
STK36 for ontologies About GeneDecksing 2 GenomeRNAi human phenotypes for STK36 :Animal Models: Mouse knock-outs for STK36: Stk36 tm1.1Ptch Stk36 tm1Lex Stk36 tm1Fjs 13 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Stk36) :
STK36 for phenotypes About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Pathways & Interactionsfor STK36 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways  - 5/8 super-pathways (see all 8 ) About this table See pathways by source Super-pathway contained gene-specific pathways 1 Basal cell carcinoma 2 Hedgehog Signaling Pathway 3 Hedgehog signaling events mediated by Gli proteins 4 Pathways in cancer 5 Activation of cAMP-Dependent PKA
Pathway sources See GeneCards unified pathways Show all pathways 4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for STK36 2 BioSystems Pathways for STK36 3
Kegg Pathways (Kegg details for STK36) :
STK36 for pathways About GeneDecksing Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for STK36 STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)5/11 Interacting proteins for STK36 (Q9NRP7 1 , 3 ENSP00000295709 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 11 )About this table Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8 ): About this table
STK36 for ontologies About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Drugs & Compoundsfor STK36 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for STK36 3 HMDB Compounds for STK36 About this table Search CenterWatch for drugs/clinical trials and news about STK36
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Transcriptsfor STK36 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for STK36 gene (2 alternative transcripts): NM_001243313.1 NM_015690.4 Unigene Cluster for STK36:
Serine/threonine kinase 36 Hs.471404 [show with all ESTs ] Unigene Representative Sequence: NM_015690 18 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000295709 (uc002viu.3 uc002viv.3 uc002vix.3 ) ENST00000392105 ENST00000455724 ENST00000440309 ENST00000468026 ENST00000473557 ENST00000424080 ENST00000414413 ENST00000422778 ENST00000470568 ENST00000480709 ENST00000492486 ENST00000486644 ENST00000473681 ENST00000431040 ENST00000419433 ENST00000462031 ENST00000392106 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for STK36 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for STK36OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: STK36 (NM_015690 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for STK36 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat STK36
Additional cDNA sequence: AB033104.1 AF200815.1 AK022692.1 AL133630.1 BC026158.2
10 DOTS entries : DT.97842563 DT.91850845
DT.212370 DT.436243 DT.97842562 DT.121035333 DT.91646592 DT.121035325 DT.121035338 DT.95135132 24/107 AceView cDNA sequences (see all 107 ):
AB033104 AI363751 BM552159 CK902114 F30327 BQ422453 BE139597 AI952933 AI124737 AI479301 AA977132 AI351935 AA578578 AF200815 AA557146 F01568 BE466736 AI499649 AW631269 CR595890 CF131939 AL133630 BQ581730 AW003323 GeneLoc Exon Structure 5/13 Alternative Splicing Database (ASD) splice patterns (SP) for STK36 (see all 13 ) About this scheme ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ SP1 :     -   -     -   -                           -     -           SP2 :     -   -     -   -                           -     -           SP3 :                                                     SP4 :                                       -               SP5 :                                                 -    
ExUns: 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26a · 26b ^ 27 ^ 28 ^ 29a · 29b ^ 30 ^ 31 SP1 :       -                 -               SP2 :       -               -   -               SP3 :                       -       -         SP4 :                                     SP5 :                                    
ECgene alternative splicing isoforms for STK36
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Expression for STK36 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section STK36 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TGATTCCAGA
About this image STK36 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See STK36 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for STK36 SOURCE GeneReport for Unigene cluster: Hs.471404 UniProtKB/Swiss-Prot: STK36_HUMAN, Q9NRP7 Tissue specificity : Expressed at low levels in most fetal tissues, adult ovaries and at high levels in adult testis,where it is localized in germ cells SABiosciences Expression via Pathway-Focused PCR Array including STK36 : Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for STK36Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat STK36 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat STK36 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STK36 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STK36
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Orthologsfor STK36 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for STK36 gene from 6/23 species (see all 23 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
STK361
serine/threonine kinase 36, fused homolog (Drosophila)
56.49(n) 48.48(a)
 
424210 XM_422059.3 XP_422059.3
lizard (Anolis carolinensis)
Reptilia
STK366
--
52(a)
1 ↔ 1
1(88239891-88267297)
zebrafish (Danio rerio)
Actinopterygii
570947602
--
74.74(n)
 
57094760
fruit fly (Drosophila melanogaster)
Insecta
fu3
egg chamber formation protein serine/threonine more
51(a)
 
1 17D1 --
thale cress (Arabidopsis thaliana)
eudicotyledons
FU6
Protein kinase family protein with ARM repeat doma...
22(a)
1 ↔ 1
1(18607047-18614162)
rice (Oryza sativa)
Liliopsida
Os.245642
Oryza sativa (japonica cultivar-group) cDNA cloneJ more
72.61(n)
 
AK102130.1
ENSEMBL Gene Tree for STK36 (if available)TreeFam Gene Tree for STK36 (if available)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Paralogsfor STK36 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for STK36 gene PDIK1L 2 ULK1 2 STK33 2 ULK2 2 ULK3 2 STK35 2 18/119 SIMAP similar genes for STK36 using alignment to 8 protein entries: STK36_HUMAN (see all proteins )
(see all similar genes ):STK32A AURKB STK33 MARK4 DAPK1 SGK110 NEK8 AURKA CDK18 KIAA0999 MYLK4 NEK5 PRKACA CDK19 CAMKV KIN27 PLK4 PRKACG
STK36 for paralogs About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Variantsfor STK36 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 2 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for STK36 (219536749 - 219567440 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for STK36 1 Indel : 11166
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing STK36
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Disorders
/ Diseasesfor STK36 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
STK36 for disorders About GeneDecksing
OMIM gene information: 607652
OMIM disorders : --7 diseases for STK36 : About MalaCards hydrocephalus primary ciliary dyskinesia ciliary dyskinesia basal cell carcinoma cerebritis immunodeficiency carcinoma 1 disease from the University of Copenhagen DISEASES database for STK36 :Primary ciliary dyskinesia Human Genome Epidemiology (HuGE) Navigator: STK36 (1 document)Export disorders for STK36 gene to outside databases
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Publicationsfor STK36 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for STK36 gene, integrated from 9 sources (see all 23 ): (articles sorted by number of sources associating them with STK36) Utopia : connect your pdf to the dynamic world of online information
Gli regulation by the opposing activities of fused and suppressor of fused. (PubMed id 10806483) 1 , 2 , 3 Murone M.... de Sauvage F.J. (2000) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462) 1 , 2 Nagase T.... Ohara O. (1999) The FU gene and its possible protein isoforms. (PubMed id 15268766) 1 , 9 Osterlund T....Toftgard R. (2004) Fused kinase is stabilized by Cdc37/Hsp90 and enhances Gli protein levels. (PubMed id 17054904) 1 , 9 Kise Y....Miki H. (2006) A possible role of mouse Fused (STK36) in Hedgehog si gnaling and Gli transcription factor regulation. (PubMed id 18600476) 1 , 9 Maloveryan A....Kogerman P. (2007) Comparative sequence analysis of the PRKAG3 region between human and pig: evolution of repetitive sequences and potential new exons. (PubMed id 14970697) 1 , 9 Amarger V....Andersson L. (2003) Congenital hydrocephalus in genetically engineered mi ce. (PubMed id 21746835) 1 Vogel P....Zambrowicz B.P. (2012) A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor. (PubMed id 18388863) 1 Turner N.C....Ashworth A. (2008)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
External Searches for STK36 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genome Databases showing STK36 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Other Databases showing STK36 gene
(According to HUGE )
About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Specialized Databases showing STK36 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for STK36 Pharmacogenomics, SNPs, Pathways
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
About This Section Patent Information for STK36 gene: Search GeneIP for patents involving STK36 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Productsfor STK36 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for STK36 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for STK36 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for STK36 Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for STK36 OriGene 3'-UTR Clone for STK36 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for STK36 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for STK36 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for STK36 OriGene Custom Protein Services for STK36 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat STK36 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing STK36 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat STK36 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat STK36 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STK36 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat STK36
Search Tocris compounds for STK36
STK36 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STK36
Search ThermoFisher Antibodies for STK36
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat STK36
Jump to Section...
Aliases for STK36
Databases for STK36
Disorders / Diseases for STK36
Domains / Families for STK36
Drugs / Compounds for STK36
Expression for STK36
Function for STK36
Genomic Views for STK36
Intellectual Property for STK36
Orthologs for STK36
Paralogs for STK36
Pathways / Interactions for STK36
Products for STK36
Proteins for STK36
Publications for STK36
Search Box for STK36
Summaries for STK36
Transcripts for STK36
Variants for STK36
TOP
BOTTOM