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STK35 Gene

protein-coding   GIFtS: 54
GCID: GC20P002082

Serine/Threonine Kinase 35

  Search for STK35
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Serine/Threonine Kinase 351 2     PDLIM1-Interacting Kinase 12 3
CLIK12 3 5     EC 2.7.11.13 8
CLP-36 Interacting Kinase1 2     Serine Threonine Kinase 35 Long Form2
Serine/Threonine-Protein Kinase 35 L12 3     Serine/Threonine-Protein Kinase 352
CLIK-12 3     PDIK13
STK35L12 3     EC 2.7.118
CLP-36-Interacting Kinase 12 3     

External Ids:    HGNC: 162541   Entrez Gene: 1409012   Ensembl: ENSG000001258347   OMIM: 6093705   UniProtKB: Q8TDR23   

Export aliases for STK35 gene to outside databases

Previous GC identifers: GC20P002070 GC20P002078 GC20P002031 GC20P002030


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for STK35 Gene:
The protein encoded by this gene is a kinase that is predominantly found in the nucleus. However, it can interact
with PDLIM1/CLP-36 in the cytoplasm and localize to actin stress fibers. The encoded protein may be a regulator
of actin stress fibers in nonmuscle cells. (provided by RefSeq, Jul 2008)

GeneCards Summary for STK35 Gene:
STK35 (serine/threonine kinase 35) is a protein-coding gene. GO annotations related to this gene include protein serine/threonine kinase activity. An important paralog of this gene is PDIK1L.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000020.10  NC_018931.2  NT_011387.9  
Regulatory elements:
   Regulatory transcription factor binding sites in the STK35 gene promoter:
         Spz1   Elk-1   Pax-5   Olf-1   PPAR-gamma1   E2F   E2F-1   HSF2   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSTK35 promoter sequence
   Search Chromatin IP Primers for STK35

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat STK35


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p13   Ensembl cytogenetic band:  20p13   HGNC cytogenetic band: 20p13

STK35 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STK35 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P002082:  view genomic region     (about GC identifiers)

Start:
2,082,257 bp from pter      End:
2,157,684 bp from pter
Size:
75,428 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: STK35_HUMAN, Q8TDR2 (See protein sequence)
Recommended Name: Serine/threonine-protein kinase 35  
Size: 534 amino acids; 58051 Da
Subunit: Interacts with PDLIM1/CLP-36
Miscellaneous: Association with PDLIM1 is controversial (PubMed:11973348)
Sequence caution: Sequence=AAI40884.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAI40885.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAG37270.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAI15590.1; Type=Erroneous gene model
prediction;
Secondary accessions: B2RBM3 C7ENV8 Q2NKW6 Q5T3R1 Q5T3R2 Q96AB4 Q9BZ06

Explore the universe of human proteins at neXtProt for STK35: NX_Q8TDR2

Explore proteomics data for STK35 at MOPED

Post-translational modifications: 

  • Autophosphorylated1
  • Ubiquitination2 at Lys503
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for STK35 (Q8TDR2) (see all 8)
     VHRDLKP  ERITFID  IVHRDLK  DLKPDNIL 


    See STK35 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_543026.2  
    ENSEMBL proteins: 
     ENSP00000370891   ENSP00000426612   ENSP00000246032   ENSP00000382937  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    IUPHAR Guide to PHARMACOLOGY protein family classification: serine/threonine kinase 35
    NKF4 family

    4 InterPro protein domains:
     IPR017441 Protein_kinase_ATP_BS
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_kinase_AS
     IPR000719 Prot_kinase_dom

    Graphical View of Domain Structure for InterPro Entry Q8TDR2

    ProtoNet protein and cluster: Q8TDR2

    UniProtKB/Swiss-Prot: STK35_HUMAN, Q8TDR2
    Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family
    Similarity: Contains 1 protein kinase domain


    Find genes that share domains with STK35           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: STK35_HUMAN, Q8TDR2
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein

         Enzyme Numbers (IUBMB): EC 2.7.11.11 2 EC 2.7.112

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity ----
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0004713protein tyrosine kinase activity ----
    GO:0005524ATP binding IEA--
    GO:0016772transferase activity, transferring phosphorus-containing groups ----
         
    Find genes that share ontologies with STK35           About GenesLikeMe


    Phenotypes:
         7 GenomeRNAi human phenotypes for STK35:
     Decreased Salmonella enterica   Decreased focal adhesion (FA)   Decreased mitotic index  Decreased substrate adherent c 
     Increased cell number in G1, s  PARP inhibitor sensitization  Paclitaxel antagonistic effect 

    Animal Models:
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    miRNA
    Products:
        
    miRTarBase miRNAs that target STK35:
    hsa-mir-185-5p (MIRT045324), hsa-mir-24-3p (MIRT030512), hsa-mir-186-5p (MIRT021181), hsa-mir-331-3p (MIRT043454), hsa-mir-128-3p (MIRT045860), hsa-mir-615-3p (MIRT040192)

    Block miRNA regulation of human, mouse, rat STK35 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate STK35 (see all 98):
    hsa-miR-124* hsa-miR-607 hsa-miR-3607-3p hsa-miR-485-3p hsa-miR-128 hsa-miR-1260b hsa-miR-200a hsa-miR-30d
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat STK35

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STK35


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    STK35_HUMAN, Q8TDR2: Nucleus. Nucleus, nucleolus. Cytoplasm. Note=When associated with PDLIM1, it is mostly found
    in cytoplasm, localized to actin stress fibers (PubMed:11973348). However, PubMed:19756140 detected STK35 only in
    the nucleus, and the presence of PDLIM1 had no influence on its location
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    extracellular1
    mitochondrion1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IEA--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with STK35           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for STK35 About    
    See pathways by source

    SuperPathContained pathways About
    1Sweet Taste Signaling
    Sperm Motility0.37

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for STK35
        Sperm Motility


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for STK35
    Interactions:

        GeneGlobe Interaction Network for STK35

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for STK35 (Q8TDR23 ENSP000002460324) via UniProtKB, MINT, STRING, and/or I2D (see all 43)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PDLIM1O001513, ENSP000003603054I2D: score=3 STRING: ENSP00000360305
    SMURF1Q9HCE73, ENSP000003546214I2D: score=2 STRING: ENSP00000354621
    BMPR1BO002383, ENSP000002645684I2D: score=3 STRING: ENSP00000264568
    SMAD4Q134853, ENSP000003415514I2D: score=3 STRING: ENSP00000341551
    TGFBR1P368973, ENSP000003641334I2D: score=3 STRING: ENSP00000364133
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----

    Find genes that share ontologies with STK35           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for STK35

    2 HMDB Compounds for STK35    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for STK35 gene: 
    NM_080836.3  

    Unigene Cluster for STK35:

    Serine/threonine kinase 35
    Hs.100057  [show with all ESTs]
    Unigene Representative Sequence: NM_080836
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000381482(uc002wfw.4 uc010zpu.2) ENST00000493263 ENST00000246032
    ENST00000400064
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate STK35 (see all 98):
    hsa-miR-124* hsa-miR-607 hsa-miR-3607-3p hsa-miR-485-3p hsa-miR-128 hsa-miR-1260b hsa-miR-200a hsa-miR-30d
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    Additional mRNA sequence: 

    AF195026.1 AK024394.1 AK026555.1 AK302629.1 AK314728.1 BC017340.2 BC111573.1 BC140883.1 
    BC140884.1 GQ281297.1 

    6 DOTS entries:

    DT.100022116  DT.308718  DT.97796291  DT.120831047  DT.95363167  DT.91865557 

    Selected AceView cDNA sequences (see all 57):

    AL040176 NM_080836 BF725825 BM561409 CR606731 CN479109 BF725826 AF195026 
    AW027332 BC017340 AW027321 AI538521 CR599328 BU729972 CK818948 BG766602 
    BF058110 AI744745 CD366998 AL844413 AU140841 BG252979 H29974 AL844417 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    STK35 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTTCTTTCT
    STK35 Expression
    About this image


    STK35 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Bone (Muscoskeletal System)
             Stylopod Long Bone
     
     Cartilage (Muscoskeletal System)
             Meckel's Cartilage
     
     Thymus (Hematopoietic System)
    STK35 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    STK35 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.100057

    UniProtKB/Swiss-Prot: STK35_HUMAN, Q8TDR2
    Tissue specificity: Expressed in testis

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for STK35 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Stk351 , 5 serine/threonine kinase 351, 5 88.72(n)1
    87.59(a)1
      2 (63.19 cM)5
    673331  NM_183262.31  NP_899085.31 
     1298005175 
    chicken
    (Gallus gallus)
    Aves STK351 serine/threonine kinase 35 81.1(n)
    86.86(a)
      771724  XM_001234967.3  XP_001234968.2 
    lizard
    (Anolis carolinensis)
    Reptilia STK356
    serine/threonine kinase 35
    91(a)
    1 ↔ 1
    GL343401.1(500630-501640)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.42352 Xenopus laevis transcribed sequence with weak similarity more 78.66(n)    BU900156.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570582392   -- 77.07(n)    57058239 
    worm
    (Caenorhabditis elegans)
    Secernentea zyg-16
    Protein ZYG-1 (zyg-1) mRNA, complete cds
    12(a)
    1 → many
    II(5649737-5654422) WBGene00006988


    ENSEMBL Gene Tree for STK35 (if available)
    TreeFam Gene Tree for STK35 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for STK35 gene
    PDIK1L2  ULK12  STK332  ULK22  ULK32  
    4 SIMAP similar genes for STK35 using alignment to 2 protein entries:     STK35_HUMAN (see all proteins):
    PDIK1L    CDK4    MAPK8    NUAK1

    Find genes that share paralogs with STK35           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for STK35 (see all 1015)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs738920081,2
    C,F--2080864(+) AGCAAG/CGGATG 1 -- us2k12Minor allele frequency- C:0.04WA 120
    rs1864283651,2
    --2081020(+) CTGGAA/TAACTA 1 -- us2k10--------
    rs1446159081,2
    --2081040(+) CCAGAC/TTAAAA 1 -- us2k10--------
    rs3689786331,2
    C--2081059(+) GAGGC-/AATGAC 1 -- us2k10--------
    rs13418081,2
    --2081103(+) ctgggA/Gaatag 1 -- us2k10--------
    rs1837806011,2
    --2081226(+) TTATGC/TCAGAT 1 -- us2k10--------
    rs1478840871,2
    --2081373(+) GATTTA/CCTTTC 1 -- us2k10--------
    rs1862967821,2
    --2081566(+) TAAGAA/GGTTTT 1 -- us2k10--------
    rs61128521,2
    C,F,A,H--2081591(+) ATTATG/AAGAAA 1 -- us2k112Minor allele frequency- A:0.19NA WA CSA EA 374
    rs61369881,2
    C,F,A,H--2081606(+) CTGTAT/CCCAGT 1 -- us2k120Minor allele frequency- C:0.35NS EA NA WA CSA 2344

    HapMap Linkage Disequilibrium report for STK35 (2082257 - 2157684 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for STK35:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv3258CNV Insertion18451855
    dgv4517n71CNV Loss21882294
    nsv470535CNV Gain18288195

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing STK35
    DNA2.0 Custom Variant and Variant Library Synthesis for STK35

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609370    OMIM disorders: --


    Find genes that share disorders with STK35           About GenesLikeMe

    Genetic Association Database (GAD): STK35

    Export disorders for STK35 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for STK35 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with STK35)
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    1. Clik1: a novel kinase targeted to actin stress fibers by the CLP-36 PDZ-LIM protein. (PubMed id 11973348)1, 2, 3 Vallenius T. and Maekelae T.P. (J. Cell Sci. 2002)
    2. Identifying and characterizing a novel protein kinase STK35L1 and deciphering its orthologs and close-homologs in vertebrates. (PubMed id 19756140)1, 2, 9 Goyal P.... Siess W. (PLoS ONE 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    6. Nuclear retention of importin I+ coordinates cell fate through changes in gene expression. (PubMed id 21964068)1 Yasuda Y....Yoneda Y. (EMBO J. 2012)
    7. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. STK35L1 associates with nuclear actin and regulates cell cycle and migration of endothelial cells. (PubMed id 21283756)1 Goyal P....Siess W. (PLoS ONE 2011)
    10. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 140901 HGNC: 16254 AceView: STK35 Ensembl:ENSG00000125834 euGenes: HUgn140901
    ECgene: STK35 H-InvDB: STK35

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for STK35 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for STK35 gene:
    Search GeneIP for patents involving STK35

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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