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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

STK35 Gene

protein-coding   GIFtS: 50
GCID: GC20P002082

serine/threonine kinase 35
  Search for STK35
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for STK35    

Aliases
for STK35 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Serine/Threonine Kinase 351 2     EC 2.7.11.13 8
CLIK11 2 3 5     BA550O8.21
Serine/Threonine-Protein Kinase 35 L12 3     CLP-36 Interacting Kinase2
CLIK-12 3     Serine Threonine Kinase 35 Long Form2
STK35L12 3     Serine/Threonine-Protein Kinase 352
CLP-36-Interacting Kinase 12 3     PDIK13
PDLIM1-Interacting Kinase 12 3     EC 2.7.118

External Ids:    HGNC: 162541   Entrez Gene: 1409012   Ensembl: ENSG000001258347   OMIM: 6093705   UniProtKB: Q8TDR23   

Export aliases for STK35 gene to outside databases

Previous GC identifers: GC20P002070 GC20P002078 GC20P002031 GC20P002030


Summaries
for STK35 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for STK35:
The protein encoded by this gene is a kinase that is predominantly found in the nucleus. However, it can interact with
PDLIM1/CLP-36 in the cytoplasm and localize to actin stress fibers. The encoded protein may be a regulator of actin
stress fibers in nonmuscle cells. (provided by RefSeq, Jul 2008)




Genomic Views
for STK35 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011387.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the STK35 gene promoter:
         Spz1   Elk-1   Pax-5   Olf-1   PPAR-gamma1   E2F   E2F-1   HSF2   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: STK35 promoter sequence
   Search SABiosciences Chromatin IP Primers for STK35

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat STK35


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p13   Ensembl cytogenetic band:  20p13   HGNC cytogenetic band: 20p13

STK35 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
STK35 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P002082:  view genomic region     (about GC identifiers)

Start:
 2,082,257 bp from pter      End:
 2,157,684 bp from pter
Size:
 75,428 bases      Orientation:
 plus strand

Proteins
for STK35 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: STK35_HUMAN, Q8TDR2 (See protein sequence)
Recommended Name: Serine/threonine-protein kinase 35  
Size: 534 amino acids; 58051 Da
Subunit: Interacts with PDLIM1/CLP-36
Subcellular location: Nucleus. Nucleus, nucleolus. Cytoplasm. Note=When associated with PDLIM1, it is mostly found in
cytoplasm, localized to actin stress fibers (PubMed:11973348). However, PubMed:19756140 detected STK35 only in the
nucleus, and the presence of PDLIM1 had no influence on its location
Miscellaneous: Association with PDLIM1 is controversial (PubMed:11973348)
Sequence caution: Sequence=AAI40884.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAI40885.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAG37270.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAI15590.1; Type=Erroneous gene model
prediction;
Secondary accessions: B2RBM3 C7ENV8 Q2NKW6 Q5T3R1 Q5T3R2 Q96AB4 Q9BZ06

Explore the universe of human proteins at neXtProt for STK35: NX_Q8TDR2

Post-translational modifications:

  • Autophosphorylated1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8TDR2

    • 4/8 DME Specific Peptides for STK35 (Q8TDR2) (see all 8)
     VHRDLKP  ERITFID  IVHRDLK  DLKPDNIL 

    STK35 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_543026.2  
    ENSEMBL proteins: 
     ENSP00000370891   ENSP00000426612   ENSP00000246032   ENSP00000382937  

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    Uscn Proteins for STK35

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IEA--
    GO:0005737cytoplasm IEA--


    STK35 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for STK35

    Protein Domains /
    Families
    for STK35 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    STK35 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR017441 Protein_kinase_ATP_BS
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_kinase_AS
     IPR000719 Prot_kinase_cat_dom

    Graphical View of Domain Structure for InterPro Entry Q8TDR2

    ProtoNet protein and cluster: Q8TDR2

    UniProtKB/Swiss-Prot: STK35_HUMAN, Q8TDR2
    Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family
    Similarity: Contains 1 protein kinase domain


    Function
    for STK35 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: STK35_HUMAN, Q8TDR2
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein

    Enzyme Numbers (IUBMB): EC 2.7.11.11 2 EC 2.7.112

    miRNA
    Products:            		 OriGene 3'-UTR Clone: STK35
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat STK35
    8/98 QIAGEN miScript miRNA Assays for microRNAs that regulate STK35 (see all 98):
    hsa-miR-124* hsa-miR-607 hsa-miR-3607-3p hsa-miR-485-3p hsa-miR-128 hsa-miR-1260b hsa-miR-200a hsa-miR-30d
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STK35 (see all 7)
    OriGene shRNA RFP: STK35
    OriGene siRNA: STK35
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat STK35

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for STK35

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for STK35 (see all 5)
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    Cell Line
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    Search LifeMap BioReagents cell lines for STK35

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for STK35

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity ----
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0005524ATP binding IEA--


    STK35 for ontologies           About GeneDecksing


    7 GenomeRNAi human phenotypes for STK35:
     Decreased Salmonella enterica   Decreased focal adhesion (FA)   Decreased mitotic index  Decreased substrate adherent c 
     Increased cell number in G1, s  PARP inhibitor sensitization  Paclitaxel antagonistic effect 


    Pathways & Interactions
    for STK35 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Sweet Taste Signaling
    		Sperm Motility0.36

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for STK35
        Sperm Motility


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for STK35

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    5/19 Interacting proteins for STK35 (Q8TDR23 ENSP000002460324) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PDLIM1O001513, ENSP000003603054I2D: score=3 STRING: ENSP00000360305
    SMURF1Q9HCE73, ENSP000003546214I2D: score=2 STRING: ENSP00000354621
    BMPR1BO002383, ENSP000002645684I2D: score=3 STRING: ENSP00000264568
    SMAD4Q134853, ENSP000003415514I2D: score=3 STRING: ENSP00000341551
    TGFBR1P368973, ENSP000003641334I2D: score=3 STRING: ENSP00000364133
    About this table

    Drugs & Compounds
    for STK35 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for STK35

    2 HMDB Compounds for STK35    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Search CenterWatch for drugs/clinical trials and news about STK35 

    Transcripts
    for STK35 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for STK35 gene: 
    NM_080836.3  

    Unigene Cluster for STK35:

    Serine/threonine kinase 35
    Hs.100057  [show with all ESTs]
    Unigene Representative Sequence: NM_080836
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000381482(uc002wfw.4 uc010zpu.2) ENST00000493263 ENST00000246032
    ENST00000400064

    miRNA
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    8/98 QIAGEN miScript miRNA Assays for microRNAs that regulate STK35 (see all 98):
    hsa-miR-124* hsa-miR-607 hsa-miR-3607-3p hsa-miR-485-3p hsa-miR-128 hsa-miR-1260b hsa-miR-200a hsa-miR-30d
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for STK35 (see all 7)
    OriGene shRNA RFP: STK35
    OriGene siRNA: STK35
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat STK35
    Clone
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    Primer
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat STK35
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat STK35
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat STK35

    Additional cDNA sequence: 

    AF195026.1 AK024394.1 AK026555.1 AK302629.1 AK314728.1 BC017340.2 BC111573.1 BC140883.1 
    BC140884.1 GQ281297.1 

    6 DOTS entries:

    DT.100022116  DT.308718  DT.97796291  DT.120831047  DT.95363167  DT.91865557 

    24/57 AceView cDNA sequences (see all 57):

    CR599328 BU729972 AW027321 BC017340 AI538521 AW027332 AF195026 BF725826 
    CN479109 CR606731 BF725825 NM_080836 BM561409 AL040176 BM126063 T10477 
    BG875928 BI964761 BM126344 CK818948 BG252979 BG768304 BU732122 CK818947 

    GeneLoc Exon Structure


    Expression
    for STK35 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    STK35 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCTTCTTTCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    STK35 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BoneStylopod Long BoneBone
    CartilageMeckel's CartilageCartilage
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See STK35 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for STK35

    SOURCE GeneReport for Unigene cluster: Hs.100057

    UniProtKB/Swiss-Prot: STK35_HUMAN, Q8TDR2
    Tissue specificity: Expressed in testis

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    In Situ
    Assay Products:     
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    Orthologs
    for STK35 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for STK35 gene from 5/15 species (see all 15)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Stk351 , 5 serine/threonine kinase 351, 5 89.54(n)1
    88.72(a)1    		   2 (63.19 cM)5
    673331  NM_183262.31  NP_899085.31 
     1298005175 
    chicken
    (Gallus gallus)    		 Aves STK351 serine/threonine kinase 35 81.1(n)
    86.86(a)    		   771724  XM_001234967.2  XP_001234968.2 
    lizard
    (Anolis carolinensis)    		 Reptilia STK356
    		 --
    		 91(a)
    		 1 ↔ 1
    		 GL343401.1(500630-501640)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.42352 Xenopus laevis transcribed sequence with weak similarity more 78.66(n)    BU900156.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii 570582392   -- 77.07(n)    57058239 


    ENSEMBL Gene Tree for STK35 (if available)
    TreeFam Gene Tree for STK35 (if available) 

    Paralogs
    for STK35 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for STK35 gene
    PDIK1L2  ULK12  STK362  STK332  ULK22  ULK32  
    5 SIMAP similar genes for STK35 using alignment to 2 protein entries:     STK35_HUMAN (see all proteins):
    PDIK1L    CDK4    MAPK8    NUAK1    HUNK

    STK35 for paralogs           About GeneDecksing



    Genomic Variants
    for STK35 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/875 NCBI SNPs in STK35 are shown (see all 875)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 20 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs738920081,2
    		C,--2080864(+) AGCAAG/CGGATG 1 -- us2k12Minor allele frequency- C:0.04WA 120
    rs1864283651,2
    		--2081020(+) CTGGAA/TAACTA 1 -- us2k10--------
    rs1446159081,2
    		--2081040(+) CCAGAC/TTAAAA 1 -- us2k10--------
    rs13418081,2
    		--2081103(+) ctgggA/Gaatag 1 -- us2k10--------
    rs1837806011,2
    		--2081226(+) TTATGC/TCAGAT 1 -- us2k10--------
    rs1478840871,2
    		--2081373(+) GATTTA/CCTTTC 1 -- us2k10--------
    rs1862967821,2
    		--2081566(+) TAAGAA/GGTTTT 1 -- us2k10--------
    rs61128521,2
    		C,F,A,H,--2081591(+) ATTATG/AAGAAA 1 -- us2k112Minor allele frequency- A:0.19NA WA CSA EA 374
    rs61369881,2
    		C,F,A,H,--2081606(+) CTGTAT/CCCAGT 1 -- us2k120Minor allele frequency- C:0.35NS EA NA WA CSA 2344
    rs1411532651,2
    		--2081715(+) GTCCT-/AAAAGTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for STK35 (2082257 - 2157684 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for STK35: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing STK35
    DNA2.0 Custom Variant and Variant Library Synthesis for STK35

    Disorders / Diseases
    for STK35 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    STK35 for disorders           About MalaCards

    STK35 for disorders           About GeneDecksing

    OMIM gene information: 609370    OMIM disorders: --


    Export disorders for STK35 gene to outside databases

    Publications
    for STK35 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for STK35 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with STK35)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Clik1: a novel kinase targeted to actin stress fibers by the CLP-36 PDZ-LIM protein. (PubMed id 11973348)1, 2, 3 Vallenius T. and Maekelae T.P. (2002)
    2. Identifying and characterizing a novel protein kinase STK35L1 and deciphering its orthologs and close-homologs in vertebrates. (PubMed id 19756140)1, 2, 9 Goyal P.... Siess W. (2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    6. Nuclear retention of importin a coordinates cell fate through changes in gene expression. (PubMed id 21964068)1 Yasuda Y....Yoneda Y. (2012)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. STK35L1 associates with nuclear actin and regulates c ell cycle and migration of endothelial cells. (PubMed id 21283756)1 Goyal P....Siess W. (2011)
    9. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    10. A germline-specific class of small RNAs binds mammali an Piwi proteins. (PubMed id 16751776)1 Girard A....Carmell M.A. (2006)

    External Searches for STK35 gene

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    Genome Databases showing STK35 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 140901 HGNC: 16254 AceView: STK35 Ensembl:ENSG00000125834 euGenes: HUgn140901
    ECgene: STK35 H-InvDB: STK35

    Other Databases showing STK35 gene

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    Specialized Databases showing STK35 gene

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    PharmGKB entry for STK35 Pharmacogenomics, SNPs, Pathways

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